Dermalogica Stabilizing Repair Cream for mature skin

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Questions and answers

What the research says

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• Moisturisers containing ceramide significantly improve SCORAD (mean difference: -0.98) compared to other moisturisers, while trans-epidermal water loss does not show a statistically significant difference.

  Indian Journal of Dermatology, 2023

• A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.

  Skin Pharmacology and Physiology, 2022

• Topical application of a pseudo-ceramide-containing spray improved stratum corneum water content, transepidermal water loss, cell area, and scaling score, and normalized the ceramide profile in patients with dry and sensitive skin compared to a control spray.

  Journal of Cosmetic Dermatology, 2025

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

Ingredients

Water, Butylene Glycol, Glycerin, Squalane, Butyrospermum Parkii Butter Shea Butter, Caprylic Capric Triglyceride, Palmitic Acid, Jojoba Seed Oil, Glyceryl Stearate Se, Propanediol, Hexyldecanol, Polyglyceryl-3 Methylglucose Distearate, Hydroxyacetophenone, Dipotassium Glycyrrhizate, Centella Asiatica Extract, Boerhavia Diffusa Root Extract, Myrothamnus Flabellifolia Stem Extract Leaf, Tasmannia Lanceolata Leaf Extract, Brassica Campestris Sterols, Zingiber Officinale Root Extract, Tocopherol, Lactobacillus Ferment, Cetylhydroxyproline Palmitamide, Caprylyl Glycol, Triolein, Maltodextrin, Bisabolol, Xanthan Gum, Cetearyl Alcohol, Myristic Acid, Tetrasodium Glutamate Diacetate, Hydroxystearic Acid, 1,2-Hexanediol, Sodium Hydroxide, Citric Acid, Sodium Polyacryloyldimethyl Taurate, Ammonium Acryloyldimethyltaurate Vp Copolymer, Stearic Acid, Acacia Senegal Gum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.