# Derma E Vitamin C Intense Night Cream for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Derma E](https://lovi.care/skincare/it/brands/derma-e)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your normal skin, this product effectively addresses wrinkles and fine lines with sodium hyaluronate and retinyl palmitate, which hydrate and promote skin rejuvenation. Tocopheryl acetate further enhances antioxidant protection, complementing your skin's needs.
- Glycerin and panthenol provide additional humectant and soothing benefits, supporting overall skin health and comfort.
- The safety profile is excellent, with no reported risks of irritation for normal skin due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Ascorbic Acid, Sodium Hyaluronate, Probiotics, Aspalathus Linearis, Retinol

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Ginkgo formulation increased skin moisturization by 27.88% and smoothness by 4.32% while reducing roughness by 0.4% and wrinkles by 4.63%, and significantly improved skin moisturization compared to the tea and rooibos formula. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20412217/))
- The addition of Aspalathus linearis extracts to topical sunscreen formulas containing OMC and BMDBM increased protection factors by up to 50% and protected the filters against photodegradation under radiation doses up to 14.4 standard erythemal doses. ([Photochemical & Photobiological Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/41591727/))
- The combination of fermented and unfermented Aspalathus linearis extracts showed a synergistic photoprotective effect on Normal Human Dermal Fibroblast survival after UVB radiation, which further improved when combined with Polypodium leucotomos extract. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40076948/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))

## What reviewers say

Based on a very large amount of data, users consistently praise this cream for its ability to brighten dull complexions and fade hyperpigmentation while providing deep hydration without a greasy residue. A significant number of recent reviews highlight irritation and redness attributed to a formula change, making it potentially unsuitable for very sensitive skin.

- Liked: Brightens and evens tone (mostly mentioned)
- Liked: Excellent hydration (often mentioned)
- Liked: Pleasant scent (often mentioned)
- Liked: Good value (sometimes noted)
- Disliked: Irritation from new formula (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Thick texture (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Derma E Vitamin C Intense Night Cream a great fit for mature skin?

Derma E Vitamin C Intense Night Cream is a great fit for mature skin because sodium hyaluronate and retinyl palmitate help smooth wrinkles and fine lines while keeping skin hydrated. Tocopheryl acetate, glycerin, and panthenol provide antioxidant protection and keep skin soft and comfortable with an excellent safety profile.
Sources: [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for mature skin?

This cream is a great fit for mature skin because it contains sodium hyaluronate and retinyl palmitate, which hydrate and help smooth out fine lines and wrinkles. Tocopheryl acetate adds antioxidant protection, while glycerin and panthenol keep the skin calm and comfortable.
Sources: [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Vitamin C do for mature skin?

Vitamin C helps mature skin by smoothing out wrinkles, brightening dark spots, and boosting firmness. It works by encouraging collagen production to keep skin looking youthful and radiant.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this cream go in a skincare routine for mature skin?

This cream is used in the evening as a treatment step after cleansing and toning, followed by a moisturizer. It helps smooth fine lines and hydrates the skin while offering strong antioxidant protection, with little likelihood of irritation.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with niacinamide, and in what order?

You can use this cream alongside niacinamide by applying niacinamide first, letting it sink in, and then smoothing on this moisturizing treatment. This combination helps keep mature skin feeling soft and comfortable while smoothing the look of fine lines.

### How often should I use this cream?

This cream is designed for evening use as part of your nighttime routine. Applying it daily helps hydrate mature skin and visibly smooth fine lines and wrinkles while protecting against irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to cause breakouts for mature skin, as it has a low risk of doing so according to reviews. However, because it features retinol, you may experience mild purging or new sensitivity as your skin adjusts to it.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment on your body, but the thin skin around the eyes needs extra care and is best suited for products with very gentle ingredients and light textures to avoid irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol and cetearyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for mature skin

- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/it/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — €82.99 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/mature-skin) — Superior fit — €12.09 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/mature-skin) — Superior fit — €18.06 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/it/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €24.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/it/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €16.03 at Amazon
- SPF: [SKIN1004 MADAGASCAR CENTELLA AIR-FIT SUNCREAM PLUS](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/mature-skin) — Superior fit — €16.03 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Caprylic Capric Triglyceride, Glycerin, Sodium Hyaluronate, Cetyl Alcohol, Ethylhexyl Palmitate, Cetearyl Alcohol, Cetearyl Glucoside, Cetyl Palmitate, Sorbitan Palmitate, Sorbitan Oleate, Diheptyl Succinate, Capryloyl Glycerin Sebacic Acid Copolymer, Pseudozyma Epicola, Prunus Armeniaca Kernel Oil Apricot Kernel Oil, Helianthus Annuus Seed Oil Sunflower Seed Oil, Prunus Amygdalus Dulcis Oil, Saururus Chinensis Extract Ferment Filtrate, Aspalathus Linearis Leaf Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Rosa Canina Oil Fruit Rosehip Oil Fruit, Camellia Sinensis Leaf Extract, Olea Europaea Oil Fruit Olive Oil Fruit, Retinyl Vitamin A Palmitate, Panthenol Vitamin B5, Tocopheryl Acetate Vitamin E, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin, Oils
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- France: https://lovi.care/skincare/fr/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin