# Derma E Vitamin C Concentrated Serum for mature skin

**Lovi Fit: Superior fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Derma E](https://lovi.care/skincare/it/brands/derma-e)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for mature skin.

## Why this fit

- Excellent for your normal skin, this serum effectively targets wrinkles and fine lines with Vitamin E and Sodium Hyaluronate to hydrate and promote collagen production, while Glycerin and Rosa Canina Seed Oil provide humectant and emollient actions.
- The inclusion of Camellia Sinensis Leaf Extract and Allantoin further supports skin health by offering antioxidant and soothing benefits.
- This formula is safe for your skin, as it contains soothing ingredients like Aloe Barbadensis Leaf Juice and Vitamin E, and lacks any harsh or prohibited components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin): Superior (this page)
- [Dry sensitive skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid, Sodium Hyaluronate, Probiotics, Camellia Sinensis Extract, Rosehip Seed Oil

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of (-)-epigallocatechin-3-gallate (EGCG) to human skin before UV irradiation decreases UV-induced production of hydrogen peroxide by 68-90% and nitric oxide by 30-100%, inhibits leukocyte infiltration and lipid peroxidation by 41-84%, and restores glutathione levels and glutathione peroxidase activity compared to UV exposure alone. ([Carcinogenesis, 2001](https://pubmed.ncbi.nlm.nih.gov/11181450/))
- Application of green tea extracts on normal human skin resulted in dose-dependent inhibition of UV-evoked erythema, reduced sunburn cells, protected Langerhans cells, and decreased UV-induced DNA damage compared to untreated UV-exposed skin. ([Journal of the American Academy of Dermatology, 2001](https://pubmed.ncbi.nlm.nih.gov/11209110/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- Topical treatments containing rosehip extract may reduce the size and erythema of postsurgical scars through macrophage polarization and inflammatory cytokine inhibition, though current clinical evidence remains insufficient to recommend its routine use. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37605366/))
- Sunflower and rosehip oil nanoemulsions prepared with a mix of phospholipids and synthetic emulsifiers permeated intact skin to the dermis and showed a more prominent healing effect in a human organotypic skin explant culture wound model compared to nanoemulsions prepared only with phospholipids. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36986857/))
- A nanoemulsion containing 1 mg/mL kojic dipalmitate and 5% rosehip oil demonstrated high incorporation efficiency, suitable physicochemical stability, antioxidant and depigmenting efficacy close to 1 mM ascorbic acid, and no cytotoxicity at concentrations from 0.06% to 1% in vitro. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36839792/))

## What reviewers say

Based on a very large amount of data, users frequently praise this serum for its ability to brighten dull complexions and provide lightweight hydration without irritating sensitive skin. A minority of users report no visible changes in hyperpigmentation or fine lines, and some experience a tacky residue or breakouts.

- Liked: Brightens skin tone (mostly mentioned)
- Liked: Gentle for sensitive skin (often mentioned)
- Liked: Lightweight and absorbs (often mentioned)
- Liked: Hydrating and softening (sometimes noted)
- Liked: Pleasant scent (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Scent dislike (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Derma E Vitamin C Concentrated Serum one of the best fits for mature skin?

This serum is one of the best fits for mature skin because it effectively targets wrinkles and fine lines with vitamin E and sodium hyaluronate to hydrate and smooth the skin. Glycerin and rosehip seed oil help lock in moisture, while green tea extract and allantoin calm the skin and provide antioxidant support.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Carcinogenesis, 2001](https://pubmed.ncbi.nlm.nih.gov/11181450/)

### Which ingredients make this serum a good fit for mature skin?

This serum is a great fit for mature skin because Ascorbic Acid, Sodium Hyaluronate, and Vitamin E hydrate and help smooth out wrinkles and fine lines, while glycerin and rosehip seed oil keep skin soft and plump. Green tea extract and allantoin further support skin health by providing soothing antioxidant benefits.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Carcinogenesis, 2001](https://pubmed.ncbi.nlm.nih.gov/11181450/)

### What does Vitamin C do for mature skin?

Vitamin C helps mature skin by smoothing out wrinkles, brightening dark spots, and boosting firmness. It works by encouraging collagen production to keep skin looking youthful and radiant.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in the evening routine after cleansing and toning, and before moisturizing. Putting it on at night helps keep things simple and keeps your skin safe from the sun.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate your skin and then following with your retinol. This approach helps minimize dryness and irritation while still targeting fine lines effectively.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. Some serums can also be used in the morning or twice a day.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to cause breakouts for mature skin, as it has a very low risk of clogged pores based on user feedback and lacks harsh components. Its soothing ingredients help keep skin calm while hydrating and smoothing fine lines.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €129.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €34.95 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/it/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €24.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/it/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €16.03 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/it/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €53.50 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Aloe Barbadensis Leaf Juice, Glycerin, Camellia Sinensis Leaf Extract, Sodium Hyaluronate, Tocopheryl Acetate Vitamin E, Polymnia Sonchifolia Root Juice, Rosa Canina Seed Oil, Lactobacillus, Citric Acid, Alpha-Glucan Oligosaccharide, Allantoin, Panthenol Vitamin B5, Cellulose Gum, Microcrystalline Cellulose, Caprylic Capric Triglyceride, Ethylhexyl Palmitate, Xanthan Gum, Maltodextrin, Sodium Citrate, Ethylhexylglycerin, Phenoxyethanol, Oil
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
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- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin