# COSRX The Niacinamide 15 Serum for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [COSRX](https://lovi.care/skincare/it/brands/cosrx)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this serum effectively addresses redness and irritation with niacinamide and zinc pca, which help regulate sebum and reduce inflammation.
- Allantoin further soothes your sensitive skin, enhancing overall comfort and hydration.
- The safety profile is excellent, with no harsh ingredients and a focus on calming components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Acetyl Glucosamine, Zinc Pca, Trehalose, Allantoin

## What the research says

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Zinc PCA inhibits UVA-induced matrix metalloproteinase-1 production through suppressed AP-1 activation and enhances type I collagen synthesis by increasing SVCT2 mRNA expression in cultured normal human dermal fibroblasts. ([International Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/21834944/))
- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Topical treatment with Thealoz Duo significantly improved dry eye disease symptoms, tear break-up time, and restored tear lipid layer functionality by reducing inflammatory response proteins in moderate to severe dry eye patients over 56 days. ([Journal of Clinical Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/40807147/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

This serum is widely praised by users with oily and acne-prone skin for its ability to significantly control sebum and refine pore texture, often delivering a smoother, "glass skin" finish. The high 15% concentration is effective for many, but frequently causes irritation, stinging, or barrier damage for those with sensitive or dry skin types. This summary is based on a very large amount of data and should be definitely taken into account.

- Liked: Controls excess oil (mostly mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Reduces pore visibility (often mentioned)
- Liked: Smoothes skin texture (often mentioned)
- Liked: Fades acne marks (sometimes noted)
- Disliked: Causes irritation (sometimes noted)
- Disliked: Too strong (sometimes noted)
- Disliked: Drying effect (rarely noted)
- Disliked: Induces breakouts (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes COSRX The Niacinamide 15 Serum a great fit for sensitive skin?

This serum is a great fit because it uses niacinamide and zinc pca to calm redness and irritation, while allantoin and trehalose soothe the skin and boost hydration. Its gentle formula avoids harsh ingredients to keep your skin comfortable.
Sources: [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it contains niacinamide and zinc pca, which help reduce inflammation and calm redness. Allantoin further soothes the skin and enhances overall comfort.
Sources: [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Acetyl Glucosamine do for sensitive skin?

Acetyl glucosamine helps keep skin hydrated and smooth while fading dark spots. It is generally gentle and unlikely to irritate dry or sensitive skin types.
Sources: [Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/), [The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19845667/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine after your toner and before your moisturizer. Putting it in the evening keeps things simple and adds extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to help calm and hydrate your skin before your retinol step. This product is a great fit for sensitive skin because it focuses on soothing components with an excellent safety profile and no harsh ingredients.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use this serum in the evening as part of your routine, and some treatments can also be used in the morning or twice a day. It has a very safe profile with calming ingredients that make it comfortable for regular use.
Sources: [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is a great fit for sensitive skin and is unlikely to cause breakouts, as it features soothing ingredients like allantoin and niacinamide that help calm redness and irritation. Reviewers rarely report breakouts from this product, though a few find it too strong, so you may want to start slowly if your skin is easily upset.
Sources: [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €129.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.10 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/it/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €17.59 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/it/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €19.21 at Amazon

## Where to buy

- Amazon.it: €22.00 (https://www.amazon.it/dp/B0BFWPQRM7?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 31 Oct 2026.

## Ingredients

Water, Pentylene Glycol, Niacinamide, Butylene Glycol, Acetyl Glucosamine, 1,2-Hexanediol, Zinc Pca, Trehalose, Hydrolyzed Sclerotium Gum, Pullulan, Allantoin, Ethylhexylglycerin, Sodium Phytate, Tocopherol, Xanthan Gum, Citric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin
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