# COSRX The Niacinamide 15 Serum for skin with dark spots

**Lovi Fit: High fit for skin with dark spots.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/dark-spots

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [COSRX](https://lovi.care/skincare/it/brands/cosrx)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for skin with dark spots; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this serum effectively addresses acne lesions and blemishes with niacinamide and zinc pca, which offer excellent seboregulation and anti-inflammatory action.
- While allantoin and trehalose provide general hydration and soothing benefits, they are not specifically targeted for your main goal of pigmentation.
- The formula is safe for your normal skin, featuring soothing ingredients like niacinamide and allantoin with no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/dark-spots): High (this page)
- [Mature skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Acetyl Glucosamine, Zinc Pca, Trehalose, Allantoin

## What the research says

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Zinc PCA inhibits UVA-induced matrix metalloproteinase-1 production through suppressed AP-1 activation and enhances type I collagen synthesis by increasing SVCT2 mRNA expression in cultured normal human dermal fibroblasts. ([International Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/21834944/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Topical treatment with Thealoz Duo significantly improved dry eye disease symptoms, tear break-up time, and restored tear lipid layer functionality by reducing inflammatory response proteins in moderate to severe dry eye patients over 56 days. ([Journal of Clinical Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/40807147/))
- An injectable product combining different molecular weights of hyaluronic acid and trehalose reduced CML formation by 45% at baseline and 30% under methylglyoxal-induced stress while preserving cell viability in human skin explants compared to untreated controls. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40244036/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24509969/))
- Prophylactic use of a topical gel containing Allium cepa extract, allantoin and heparin significantly reduced vascularity, pigmentation and height of scars compared to an untreated control group and in intra-individual analysis in 120 patients after caesarean section. ([Journal of Wound Care, 2020](https://pubmed.ncbi.nlm.nih.gov/33052789/))

## What reviewers say

This serum is widely praised by users with oily and acne-prone skin for its ability to significantly control sebum and refine pore texture, often delivering a smoother, "glass skin" finish. The high 15% concentration is effective for many, but frequently causes irritation, stinging, or barrier damage for those with sensitive or dry skin types. This summary is based on a very large amount of data and should be definitely taken into account.

- Liked: Controls excess oil (mostly mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Reduces pore visibility (often mentioned)
- Liked: Smoothes skin texture (often mentioned)
- Liked: Fades acne marks (sometimes noted)
- Disliked: Causes irritation (sometimes noted)
- Disliked: Too strong (sometimes noted)
- Disliked: Drying effect (rarely noted)
- Disliked: Induces breakouts (rarely noted)

## How to apply

- Apply this serum as part of your PM routine starting 3x/week and build up to daily use if your skin likes it.
- Place the serum after cleansing and toning, but before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute for it to absorb.
- Apply the serum on dry skin to help fade pigmentation effectively.
- Avoid the eye area and always use SPF 30+ during the day.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes COSRX Niacinamide 15 Serum a great fit for skin with dark spots?

This serum is a great fit because it contains niacinamide, which helps fade dark spots and brighten skin. Additionally, zinc pca and niacinamide help calm acne lesions and blemishes with very little risk of irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/)

### Which ingredients make this serum a good fit for skin with dark spots?

Niacinamide is the key ingredient that makes this serum a great fit for skin with dark spots, as it helps fade dark areas and brighten the skin. The formula is also very safe for your skin, featuring soothing ingredients with no risk of irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Niacinamide do for skin with dark spots?

Niacinamide helps fade dark spots and uneven pigmentation by slowing down the transfer of pigment in the skin. It is generally well tolerated and may improve overall skin brightness with consistent use.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Acetyl Glucosamine do for skin with dark spots?

Acetyl glucosamine helps fade dark spots and makes skin tone more even. Clinical studies show that it visibly reduces facial hyperpigmentation and brightens the skin.
Sources: [The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19845667/), [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/)

### Where does this serum go in a skincare routine for skin with dark spots?

This serum goes in the evening routine after cleansing and before moisturizing, which keeps things simple and safe around sun exposure. Ingredients like niacinamide help balance oil and calm the skin while you address dark spots.

### Can I use this serum with retinol, and in what order?

You can use this serum alongside retinol by applying the serum first to clean skin and following with your retinol after it absorbs. This approach helps keep your skin calm and comfortable while supporting your overall routine.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

Use this serum in the evening as part of your routine. This timing keeps things simple and adds extra safety around sun exposure.

### Can this serum clog pores, cause breakouts or purging for skin with dark spots?

This serum is unlikely to cause breakouts, as reviewers rarely report this issue and the formula features soothing ingredients with a low risk of irritation. However, some users do experience moderate irritation or find the formula too strong.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for skin with dark spots

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dark-spots) — Superior fit — €57.00 at Amazon
- [Guerlain Abeille Royale Double R Renew & Repair Serum](https://lovi.care/skincare/it/p/guerlain/abeille-royale-double-r-renew-and-repair-advanced-serum/for/dark-spots) — High fit — €132.56 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/it/p/la-mer/the-regenerating-serum/for/dark-spots) — High fit — €396.14 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/dark-spots) — Superior fit — €24.75 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dark-spots) — Superior fit — €15.16 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/dark-spots) — Superior fit — €18.06 at Amazon

## Where to buy

- Amazon.it: €22.00 (https://www.amazon.it/dp/B0BFWPQRM7?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 31 Oct 2026.

## Ingredients

Water, Pentylene Glycol, Niacinamide, Butylene Glycol, Acetyl Glucosamine, 1,2-Hexanediol, Zinc Pca, Trehalose, Hydrolyzed Sclerotium Gum, Pullulan, Allantoin, Ethylhexylglycerin, Sodium Phytate, Tocopherol, Xanthan Gum, Citric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cosrx/the-niacinamide-15-serum/for/dark-spots
- United Kingdom: https://lovi.care/skincare/uk/p/cosrx/the-niacinamide-15-serum/for/dark-spots
- Ireland: https://lovi.care/skincare/ie/p/cosrx/the-niacinamide-15-serum/for/dark-spots
- Germany: https://lovi.care/skincare/de/p/cosrx/the-niacinamide-15-serum/for/dark-spots
- France: https://lovi.care/skincare/fr/p/cosrx/the-niacinamide-15-serum/for/dark-spots
- Italy: https://lovi.care/skincare/it/p/cosrx/the-niacinamide-15-serum/for/dark-spots (this page)
- Netherlands: https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/dark-spots
- Spain: https://lovi.care/skincare/es/p/cosrx/the-niacinamide-15-serum/for/dark-spots
- Canada: https://lovi.care/skincare/ca/p/cosrx/the-niacinamide-15-serum/for/dark-spots
- Australia: https://lovi.care/skincare/au/p/cosrx/the-niacinamide-15-serum/for/dark-spots
- Singapore: https://lovi.care/skincare/sg/p/cosrx/the-niacinamide-15-serum/for/dark-spots
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- United Arab Emirates: https://lovi.care/skincare/ae/p/cosrx/the-niacinamide-15-serum/for/dark-spots