# cocokind Resurrection Polypeptide Cream for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [cocokind](https://lovi.care/skincare/it/brands/cocokind)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Excellent for your normal skin, this cream effectively targets wrinkles and fine lines with Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 to boost collagen production and skin regeneration.
- Squalane and glycerin provide excellent moisturizing benefits, enhancing barrier resilience and hydration for your normal skin type.
- The product is safe for your skin, featuring soothing ingredients like watermelon seed oil and shea butter with no harsh components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/oily-acne-prone-skin): High

## Key ingredients

Watermelon Seed Oil, Squalane, Butyrospermum Parkii Butter Shea Butter, Glycerin, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone. ([The New England Journal of Medicine, 1989](https://pubmed.ncbi.nlm.nih.gov/2659995/))
- Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba. ([Lasers in Surgery and Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/30614013/))
- Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars. ([The Journal of Clinical and Aesthetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35942017/))

## What reviewers say

Based on a very large amount of data, this rich cream is highly praised for its ability to deeply hydrate and plump dry, dehydrated skin, leaving a unique velvety, non-greasy finish. Many users find it to be a great value and suitable for sensitive skin. Some users with acne-prone skin reported congestion, and others found the texture difficult to spread or prone to pilling.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Velvety finish (often mentioned)
- Liked: Great value (sometimes noted)
- Liked: Soothing for sensitive skin (sometimes noted)
- Disliked: Pills under makeup (sometimes noted)
- Disliked: Thick texture (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes cocokind Resurrection Polypeptide Cream a great fit for mature skin?

This cream is a great fit because it targets wrinkles and fine lines with peptides that boost collagen and skin renewal. Squalane and glycerin also provide deep moisture to help keep your skin feeling soft and smooth.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for mature skin?

This cream is a great fit because Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 helps boost collagen production and smooth out wrinkles and fine lines. Squalane and glycerin also provide great moisture to keep your skin hydrated, while watermelon seed oil and shea butter soothe your skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Watermelon Seed Oil do for mature skin?

Watermelon Seed Oil helps keep mature skin feeling soft and smooth while providing extra moisture. It is light and absorbs easily, making dry skin feel comfortable without a heavy or greasy layer.

### What does Squalane do for mature skin?

Squalane helps keep mature skin feeling soft and smooth by boosting moisture and protecting the skin barrier. It also provides antioxidant support that helps improve the look of fine lines and wrinkles over time.
Sources: [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/), [Journal of Nanoscience and Nanotechnology, 2010](https://pubmed.ncbi.nlm.nih.gov/21137794/)

### Where does this cream go in a skincare routine for mature skin?

This moisturizing treatment goes near the end of your morning and evening routines, right before sunscreen in the morning and as the final step at night. Using a moisturizer helps lock in hydration and supports your skin barrier.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it first helps prepare your skin and may reduce dryness or irritation. Barrier-enhancing moisturizers like this one support your skin during strong treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice a day as part of your morning and evening routine to keep your skin hydrated and smooth. Regular daily application helps improve fine lines, wrinkles, and overall skin barrier strength.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to cause breakouts for mature skin because it features soothing ingredients like watermelon seed oil and shea butter with no harsh components, and user complaints about breakouts are low.
Sources: [Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/)

### Can I use this cream around the eyes or on my body?

You can use this cream around your eyes to help smooth fine lines, and it is also gentle enough to use on your body. The skin in these areas can be quite thin and delicate, but this formula's soothing squalane and glycerin help keep it hydrated without irritation.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/24056055/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/it/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — €82.99 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/mature-skin) — Superior fit — €12.09 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/mature-skin) — Superior fit — €18.06 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/it/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €24.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/it/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €16.03 at Amazon
- SPF: [SKIN1004 MADAGASCAR CENTELLA AIR-FIT SUNCREAM PLUS](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/mature-skin) — Superior fit — €16.03 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Watermelon Seed Oil, Squalane, Triolein, Musa Sapientum Leaf Extract, Glycerin, Betaine, Cetearyl Olivate, Butyrospermum Parkii Butter Shea Butter, Crambe Abyssinica Seed Oil, Phytosterol Esters, Glyceryl Stearate Se, Jojoba Esters, Selaginella Lepidophylla Extract, Cetearyl Alcohol, Sorbitan Olivate, Cetyl Palmitate, Butylene Glycol, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, Citric Acid, Willow Bark Extract, Genipa Americana Fruit Extract, Sorbitan Palmitate, Sorbitan Oleate, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cocokind/resurrection-polypeptide-cream/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cocokind/resurrection-polypeptide-cream/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/cocokind/resurrection-polypeptide-cream/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/cocokind/resurrection-polypeptide-cream/for/mature-skin
- France: https://lovi.care/skincare/fr/p/cocokind/resurrection-polypeptide-cream/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/cocokind/resurrection-polypeptide-cream/for/mature-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/cocokind/resurrection-polypeptide-cream/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/cocokind/resurrection-polypeptide-cream/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/cocokind/resurrection-polypeptide-cream/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/cocokind/resurrection-polypeptide-cream/for/mature-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/cocokind/resurrection-polypeptide-cream/for/mature-skin