# Clé de Peau Beauté La Crème for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Clé de Peau Beauté](https://lovi.care/skincare/it/brands/cle-de-peau-beaute)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration for your combination skin due to glycerin and squalane, which support barrier function but do not specifically target acne or breakouts.
- While the formula is safe and free of irritants for your combination skin, it lacks key ingredients like salicylic acid for effective acne treatment.
- The product is safe for your combination skin as it contains no harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/oily-acne-prone-skin): Average

## Key ingredients

Squalane, Glycerin, Licorice Root Extract, Retinyl Acetate, Shea Butter

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))

## Why other moisturizers fit acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

Users consistently describe this cream as the "gold standard" of luxury moisturizers, praising its ability to transform dry, dull, and mature skin into a plump, "baby-soft" complexion overnight. While the exorbitant price point is a universal point of contention, the majority of reviewers report visible improvements in radiance, texture, and hydration that justify the investment.

- Liked: Radiant glow (mostly mentioned)
- Disliked: Exorbitant price (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Luxurious texture (often mentioned)
- Liked: Anti-aging results (sometimes noted)
- Liked: Exquisite packaging (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)
- Disliked: Diminishing returns (rarely noted)
- Disliked: Too rich for oily skin (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Clé de Peau La Crème work for acne-prone skin?

This moisturizing treatment works for acne-prone skin by offering moderate hydration and keeping skin soft, though other products fit this skin type better. Skincare for this skin needs effective ingredients that target breakouts and blemishes, along with soothing agents that hydrate without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for acne-prone skin?

Glycerin and squalane help make this cream a moderate fit by supporting skin hydration, though an acne-prone skin type needs targeted blemish-fighting ingredients like salicylic acid and soothing extracts to care for breakouts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Squalane do for acne-prone skin?

Squalane may help keep acne-prone skin soft and smooth, but peroxidated forms can trigger inflammation in skin cells. For a better fit on acne-prone skin, products need non-clogging, soothing ingredients that balance oil without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### What does Glycerin do for acne-prone skin?

Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### Where does it go in a skincare routine for acne-prone skin?

This moisturizer works as the final step of your evening routine, after your treatment and cleanser. While it is safe for acne-prone skin, a product of this type needs acne-fighting ingredients like salicylic acid to properly care for breakouts.

### Can I use this cream with retinol, and in what order?

Yes, you can use this cream alongside retinol by applying the retinol first and following it with this moisturizer. This order helps keep your skin soft and calm while reducing dryness and irritation when using retinoids. To get the best results for acne-prone skin, a product of this type needs acne-fighting ingredients like salicylic acid or soothing botanical extracts to help clear breakouts.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use it?

You can use this moisturizing treatment twice daily to help keep your skin soft and hydrated. Daily application of this type of product is unlikely to cause irritation and supports your skin barrier, though acne-prone skin also needs targeted ingredients like salicylic acid to effectively manage breakouts.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to cause purging, but it may feel too rich and potentially clog pores for acne-prone skin because it focuses on general moisture rather than treating breakouts. A product for this skin needs targeted ingredients like salicylic acid to help clear and prevent blemishes.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use it around the eyes or on my body?

You can use this moisturizing treatment on both the body and the thin skin around the eyes, as it has a very safe formula with good skin tolerance. Moisturizers of this type used in these areas need rich hydrators like glycerin and squalane to keep the skin soft and smooth, along with botanical extracts to help calm it.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

It contains fragrance (parfum, hexyl cinnamal, citronellol, limonene, linalool, geraniol, and zingiber aromaticus extract) and drying alcohol (alcohol).

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €18.06 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — €12.09 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/it/p/drunk-elephant/protini-polypeptide-cream/for/acne-prone-skin) — Superior fit — €92.92 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/it/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.43 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/acne-prone-skin) — Superior fit — €103.91 at Amazon
- SPF: [SKIN1004 Madagascar Centella Air-Fit Suncream Plus](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-air-fit-suncream-plus/for/acne-prone-skin) — Superior fit — €16.03 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Pentaerythrityl Tetraethylhexanoate, Glycerin, Butylene Glycol, Triisostearin, Squalane, Behenyl Alcohol, Trehalose, Isodecyl Neopentanoate, Petrolatum, Dimethicone, Maltitol, Potassium Methoxysalicylate, Hydrogenated Polyisobutene, Stearyl Alcohol, Myristyl Myristate, Beheneth-20, Phenoxyethanol, Butyrospermum Parkii Butter Shea Butter, Silica, Theanine, Dimethylacrylamide Sodium Acryloyldimethyltaurate Crosspolymer, Microcrystalline Wax Cera Microcristallina Cire Microcristalline Wax Cera, Caprylic Capric Triglyceride, Phytosteryl Macadamiate, Trisodium Edta, Polyvinyl Alcohol, Peg Ppg-14 7 Dimethyl Ether, Peg Ppg-17 4 Dimethyl Ether, Tocopheryl Acetate, Retinyl Acetate, Parfum, Sodium Citrate, Helianthus Annuus Seed Oil Sunflower Seed Oil, Alcohol, Bht, Hydrogenated Oil, Citric Acid, Sodium Metabisulfite, Sodium Metaphosphate, Ectoin, Dipotassium Glycyrrhizate, Iron Oxides Ci 77492, Hexyl Cinnamal, Citronellol, Alpha-Isomethyl Ionone, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Limonene, Linalool, Lilium Candidum Bulb Extract, Geraniol, Angelica Acutiloba Root Extract, Benzyl Benzoate, Hydrolyzed Silk, Olea Europaea Leaf Extract Olive Leaf Extract, Iris Florentina Root Extract, Paeonia Albiflora Root Extract, Sanguisorba Officinalis Root Extract, Crataegus Monogyna Flower Extract, Fagus Sylvatica Bud Extract, Panax Ginseng Root Extract, Glycine, Rubus Suavissimus Leaf Extract Raspberry Leaf Extract, Inositol, Tocopherol, Pinus Sylvestris Cone Extract, Camellia Sinensis Leaf Extract, Rosamarinus Officinalis Leaf Extract Rosemary Leaf Extract, Iron Oxides Ci 77491, Rosa Canina Fruit Extract, Perilla Ocymoides Leaf Extract, Serine, Zingiber Aromaticus Extract, Sodium Acetylated Hyaluronate, Isostearic Acid, Hydrolyzed Yeast, Benzoic Acid, Hydrolyzed Conchiolin Protein, Lauryl Betaine, Potentilla Erecta Root Extract, Polysorbate 20, Uncaria Gambir Extract, Sodium Carboxymethyl Beta-Glucan, Centaurea Cyanus Flower Extract, Bupleurum Falcatum Root Extract, Sodium Benzoate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cle-de-peau-beaute/la-creme/for/acne-prone-skin