Cetaphil Rich Hydrating Night Cream for mature skin
Sodium Hyaluronate
Glycerin
Tocopheryl Acetate Vitamin E
Ascorbyl Palmitate Ascorbic Acid
Olea Europaea Oil Fruit Olive Oil FruitHigh
- HighNormal Skin Fit
- HighEffectiveness
- ExcellentSafety
A great choice for mature skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your normal skin due to the presence of glycerin and hydrolyzed hyaluronic acid, which provide excellent humectant action to hydrate and plump the skin.
- The inclusion of retinyl palmitate offers moderate benefits for wrinkles and fine lines by promoting cell turnover, while vitamin E and ascorbic acid provide antioxidant protection.
- The product is safe for your skin, as it contains no harsh ingredients and includes soothing components like vitamin E.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
People Say
★4.6Overall rating based on 2.5k+ reviewsBased on a very large amount of data, this cream is highly effective for dry, sensitive, and acne-prone skin, providing deep hydration and improving skin texture without irritation or clogging pores. Users frequently praise its non-greasy, fragrance-free formula that absorbs quickly. A common concern is the small quantity relative to the price, with a few users experiencing breakouts or finding it too heavy or insufficient for extremely dry skin.
Highlights
Intense hydration Mostly Mentioned
- “leaves skin soft”
- “deeply hydrates”
- “restores moisture”
- “plump skin”
Fragrance-free Often Mentioned
- “no scent”
- “odorless”
- “great for sensitivity”
- “no added fragrance”
Gentle on sensitivity Often Mentioned
- “good for sensitive skin”
- “no redness”
- “soothing”
- “doesn't burn”
Non-greasy texture Often Mentioned
- “absorbs quickly”
- “lightweight feel”
- “no sticky residue”
- “melts into skin”
Small quantity Often Mentioned
- “small jar”
- “wish it was bigger”
- “expensive for size”
- “runs out fast”
Improves skin texture Sometimes Noted
- “smooths fine lines”
- “skin feels bouncier”
- “dewy look”
- “eliminates flakes”
Caused breakouts Rarely Noted
- “caused cystic acne”
- “closed comedones”
- “tiny spots”
- “reaction spots”
Not enough moisture Rarely Noted
- “still dry”
- “need more layers”
- “not for very dry skin”
- “absorbed too fast”
Too heavy Rarely Noted
- “too thick”
- “feels heavy”
- “sits on top”
- “greasy for oily skin”
Sources: lovi.care, walmart.com, target.com, kroger.com, hollandandbarrett.com, influenster.com, and more
Questions and answers
What makes Cetaphil Rich Hydrating Night Cream a great fit for mature skin?
Cetaphil Rich Hydrating Night Cream is a great fit for mature skin because it uses glycerin and hyaluronic acid to hydrate and plump the skin, while vitamin A helps smooth fine lines and wrinkles. Vitamins E and C also provide antioxidant protection with a safe formula that is unlikely to irritate your skin.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2013
Which ingredients make this cream a good fit for mature skin?
This cream is a great fit for mature skin because it contains glycerin and hydrolyzed hyaluronic acid to deeply hydrate and plump, along with retinyl palmitate to help smooth fine lines and wrinkles. It also includes vitamin E and ascorbic acid to provide helpful antioxidant protection while keeping the skin calm.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2013
What does Hyaluronic Acid do for mature skin?
Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Journal of Drugs in Dermatology, 2011Skin Research and Technology, 2024
What does Glycerin do for mature skin?
Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
The British Journal of Dermatology, 2008Clinical, Cosmetic and Investigational Dermatology, 2017
Where does this cream go in a skincare routine for mature skin?
This cream goes last in your evening routine and before your sunscreen in the morning. It helps keep your skin hydrated and smooth while providing gentle antioxidant protection.
The Journal of Dermatological Treatment, 2022Journal of Drugs in Dermatology, 2023
Can I use this cream with niacinamide, and in what order?
You can use this cream with niacinamide by applying your niacinamide serum first and following with this moisturizer. This combination is generally safe and helps hydrate and smooth mature skin while protecting it from irritation.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2013
How often should I use this cream?
You can use this cream twice a day as part of your morning and evening routine to keep mature skin hydrated and smooth. Regular daily application helps improve fine lines, wrinkles, and overall skin texture.
Journal of Cosmetic Dermatology, 2020Journal of Drugs in Dermatology, 2015
Can this cream clog pores, cause breakouts or purging for mature skin?
This cream is unlikely to clog pores or cause breakouts, as it is free of harsh ingredients and features soothing components that are safe for your skin. Reviewers rarely complain about breakouts, and the vitamin E it contains is unlikely to clog pores.
Can I use this cream around the eyes or on my body?
This cream is generally safe to apply around the eyes and on the body because it features a gentle formula without harsh ingredients. However, because the skin around the eyes and on certain body areas is much thinner than facial skin, you should watch for any sensitivity when trying it on new areas.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability.
Aesthetic Plastic Surgery, 2026A vitamin A palmitate and antioxidant-containing oil-based moisturizer improved fine lines, wrinkles, pigmentation, tone, texture, dryness, firmness, and clarity across various body sites compared to a no-treatment group over 12 weeks.
Journal of Cosmetic Dermatology, 2013Retinyl palmitate-loaded non-ionic lamellar liquid crystalline systems provided a significant reduction of orbicular wrinkles in human volunteers compared to systems without retinyl palmitate.
Colloids and Surfaces. B, Biointerfaces, 2011Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use.
Journal of Cosmetic Dermatology, 2022Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022
Ingredients
Water, Hydrogenated Polydecene, Caprylic Capric Triglyceride, Dimethicone, Glycerin, Butylene Glycol, Cetearyl Olivate, Sorbitan Olivate, Cyclopentasiloxane, Marrubium Vulgare Extract, Hydrolyzed Hyaluronic Acid, Olea Europaea Oil Fruit Olive Oil Fruit, Tocopheryl Acetate Vitamin E, Ascorbyl Palmitate Ascorbic Acid, Leuconostoc Radish Root Ferment Filtrate, Isopropyl Lauroyl Sarcosinate, Cetearyl Alcohol, Sodium Polyacrylate, 1,2-Hexanediol, Caprylyl Glycol, Polymethylsilsesquioxane, Isohexadecane, Glyceryl Stearate, Peg-100 Stearate, Cetearyl Methicone, Phenoxyethanol, Peg-40 Stearate, Steareth-2, Steareth-21, Retinyl Palmitate, Linoleic Acid, Lycopene
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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