Cetaphil Eye Serum for dry skin

Questions and answers

What the research says

• A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin.

  Acta Dermato-venereologica, 2017

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• A Dunaliella salina extract significantly reduced skin glycation scores, histamine sensitivity, wrinkle counts, and spots compared to placebo under intense solar exposure.

  Marine Drugs, 2022

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.

  Colloids and Surfaces. B, Biointerfaces, 2025

Ingredients

Water, Dicaprylyl Carbonate, Glycerin, 1,2-Hexanediol, Polyglyceryl-6 Distearate, Distarch Phosphate, 4-T-Butylcyclohexanol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Anhydroxylitol, Bisabolol, Caprylyl Capryl Glucoside, Cetyl Alcohol, Citric Acid, Dunaliella Salina Extract, Ethylhexylglycerin, Globularia Alypum Leaf Extract, Hydrolyzed Hyaluronic Acid, Jojoba Esters, Palmitoyl Tripeptide-5, Panthenol, Pantolactone, Pentylene Glycol, Phenoxyethanol, Polyglyceryl-3 Beeswax, Polyisobutene, Potassium Sorbate, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Sodium Benzoate, Hyaluronic Acid, Sodium Hydroxide, Sodium Pca, Sorbitan Oleate, Tocopherol, Xylitol, Xylitylglucoside

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.