Cetaphil Daily Facial Moisturizer for acne-prone skin
Avobenzone
Octocrylene
Glycerin
Niacinamide
Tocopheryl Acetate Vitamin EHigh
- HighCombination Skin Fit
- HighEffectiveness
- HighSafety
A great choice for acne-prone skin; a few sunscreens fit it even better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent sun protection for your combination skin due to avobenzone and octocrylene, while niacinamide and panthenol help soothe inflammation and reduce breakouts.
- Glycerin and niacinamide work synergistically to balance oil production and hydration, making it highly suitable for combination skin.
- The product is safe for your acne-prone skin, as it contains no harsh or prohibited ingredients that could cause irritation.
How to apply
- Apply this moisturizing sunscreen AM every morning as the final step of your daily routine.
- Layer the moisturizing sunscreen after your moisturizer has fully absorbed, right before heading out into the sun .
- Smooth a nickel-sized amount of the moisturizing sunscreen evenly over your face, avoiding harsh rubbing.
- Apply the moisturizing sunscreen onto clean, dry skin to ensure even coverage and protection.
- Perform a patch test before first use and avoid direct contact with the eyes.
People Say
★4.3Overall rating based on 3.5k+ reviewsBased on a very large amount of data, users with sensitive and combination skin frequently praise this moisturizer for being lightweight and non-irritating, often noting it provides effective hydration without clogging pores or causing acne breakouts. A notable subset of users experiences a burning or stinging sensation upon application, and those with darker skin tones often report a visible white cast, particularly with the SPF 35 and SPF 50 versions.
Highlights
Gentle for sensitive skin Often Mentioned
- “Great for my acne-prone skin, doesn't cause breakouts.”
Lightweight & non-greasy Often Mentioned
- “Glides on smoothly and absorbs quickly without leaving residue.”
- “Feels light on the skin, not heavy or sticky like other sunscreens.”
- “Perfect for under makeup because it isn't oily.”
Effective hydration Sometimes Noted
- “Keeps my dry patches moisturized all day.”
- “Leaves my skin feeling soft and plump.”
- “Good balance of moisture for my combination skin.”
Fragrance-free Sometimes Noted
- “Love that it has no strong perfume smell.”
- “Great for people sensitive to scents.”
- “Doesn't clash with my perfume.”
Burning sensation Sometimes Noted
- “Stings my face immediately after applying.”
- “Causes a burning feeling around my eyes.”
- “Had to wash it off because the burning wouldn't stop.”
White cast Sometimes Noted
- “Leaves a purple/white film on my dark skin.”
- “Takes a long time to rub in so I don't look pale.”
- “The SPF 50 version makes me look like a ghost.”
Eye irritation Rarely Noted
- “Makes my eyes water if I get it anywhere near them.”
- “Migrates into my eyes and stings badly.”
- “Can't use it on my forehead because it runs into my eyes.”
Greasy finish Rarely Noted
- “Left my face looking shiny and oily by midday.”
- “Felt like a layer of grease sitting on top of my skin.”
- “Too heavy for my very oily skin type.”
Sources: lovi.care, walmart.com, ulta.com, cetaphil.com, amazon.com, and more
Questions and answers
What makes Cetaphil Daily Facial Moisturizer a great fit for acne-prone skin?
Cetaphil Daily Facial Moisturizer is a great fit for acne-prone skin because it offers sun protection while niacinamide and panthenol help soothe inflammation and reduce breakouts. Glycerin and niacinamide also work together to balance oil and hydration without causing irritation.
Archives of Dermatological Research, 2024Contemporary Clinical Trials Communications, 2021
Which ingredients make this moisturizer a good fit for acne-prone skin?
Niacinamide and panthenol help soothe inflammation and reduce breakouts, while glycerin helps balance oil and hydration. It is safe for acne-prone skin because it contains no harsh or prohibited ingredients that could cause irritation.
What does Avobenzone do for acne-prone skin?
Avobenzone protects acne-prone skin from UV rays that can worsen dark spots and inflammation, though it does not directly treat breakouts. To properly care for acne-prone skin, sunscreens should also feel light, clog-free, and non-greasy.
What does Octocrylene do for acne-prone skin?
Octocrylene is a sunscreen ingredient that protects acne-prone skin from UV rays without disturbing the balance of bacteria living on the face. It is unlikely to trigger breakouts, but a sunscreen for this skin type still needs a lightweight, non-greasy texture and ingredients that do not clog pores.
Where does this moisturizer go in a skincare routine for acne-prone skin?
This moisturizer goes in the morning step of your routine right after your hydrating toner and before your sunscreen. It is a great fit for your acne-prone skin because ingredients like glycerin and niacinamide balance oil and hydration while soothing inflammation.
Can I use this moisturizer with retinol, and in what order?
You can use this moisturizer with retinol by applying your retinol first and following it with this product to keep your skin calm and hydrated. Using a moisturizing cream with active ingredients like niacinamide and panthenol helps soothe inflammation and supports your skin barrier while you use retinoids.
How often should I use this moisturizer?
You can use this moisturizer every morning as part of your daily routine to protect your skin and keep it hydrated. Its formula helps calm breakouts and balance oil production safely without causing irritation.
Health Science Reports, 2021Archives of Dermatological Research, 2024
Can this moisturizer clog pores, cause breakouts or purging for acne-prone skin?
This moisturizer is a great fit for acne-prone skin because it contains no harsh or prohibited ingredients that are likely to cause irritation or breakouts. Glycerin and niacinamide work together to balance oil and hydration, while vitamin E has been shown in studies to have a safe, non-comedogenic profile.
Is this moisturizer fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.
What the research says
Incorporating rosmarinic acid into sunscreens enhanced the in vivo SPF of octocrylene by over 157% and reduced lipid peroxidation in the human stratum corneum.
Antioxidants, 2025Encapsulating avobenzone in low-porosity TiO2-embedded mesoporous silica (TiO2/SBA-S) reduced cutaneous avobenzone absorption from 0.76 to 0.50 nmol/mg while providing effective pollutant adsorbability, UVA protection, and a two- to three-fold reduction in photoaged skin cytokines/chemokines compared to the non-treatment control.
European Journal of Pharmaceutical Sciences, 2023A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017The application of a sunscreen formulation containing ethylhexyl methoxycinnamate, ethylhexyl salicylate, methyl anthranilate, and octocrylene does not significantly affect critical acne-related species such as Cutibacterium acnes and Staphylococcus epidermidis, refuting the induction of facial dysbiosis in men.
Archives of Dermatological Research, 2024Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.
Skin Pharmacology and Physiology, 2011Microencapsulation of the BMDBM/HP-beta-CD complex in lipid microparticles significantly decreased the percutaneous penetration of the UV filter into the stratum corneum of human volunteers compared to the non-encapsulated sunscreen agent.
Journal of Pharmaceutical and Biomedical Analysis, 2011Following human skin application of an O/W emulsion containing 2% BMDBM loaded in lipospheres, 15% of the sunscreen accumulated in the uppermost layers of the stratum corneum without remarkably modifying skin permeation compared to unencapsulated sunscreen.
Skin Pharmacology and Physiology, 2008Early application of sunscreen after ablative fractional skin resurfacing significantly increased the sensitization rate of the UV-filter, octocrylene, and the sunscreen compared to intact skin.
The Journal of Dermatological Treatment, 2015Dermal sunscreen exposure in 20 healthy volunteers led to plasma concentrations of avobenzone, octocrylene, and its metabolite CDAA reaching up to 11 μg/L, 25 μg/L, and 1352 μg/L, respectively.
Environment International, 2019Chemical sunscreens containing avobenzone, octocrylene, homosalate, and octisalate showed no to minimal risks of dermal irritation, sensitization, photo-allergy, and photo-irritation in human subjects.
Journal of Drugs in Dermatology, 2025The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use.
Journal of Cosmetic Dermatology, 2022
Ingredients
Water, Glycerin, Dipropylene Glycol, Panthenol Vitamin B5, Ethylhexyl Methoxycrylene, Isopropyl Palmitate, Silica, Niacinamide, Cetearyl Olivate, Cetearyl Alcohol, Glyceryl Stearate, Potassium Cetyl Phosphate, Sorbitan Olivate, Tocopheryl Acetate Vitamin E Acetate, Caprylyl Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Palmitic Acid, Ethylhexylglycerin, Leontopodium Extract Leontopodium Alpinum Extract, Stearic Acid, 1,2-Hexanediol, Rice Extract Lees Extract, Propanediol, Sodium Hydroxide, Adenosine, Potassium Sorbate, Sodium Benzoate, Citric Acid, Myristic Acid, Buddleja Davidii Leaf Extract, Thymus Vulgaris Leaf Extract, Tocopherol Vitamin E, Avobenzone, Octocrylene
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Dermatology and diagnostic consultant
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Victoria Derkova, MS
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Cosmetic chemist, cosmetic development technologist
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