# Cetaphil Ceramide Serum for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Cetaphil](https://lovi.care/skincare/it/brands/cetaphil)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for dry sensitive skin.

## Why this fit

- Excellent suitability for your dry and sensitive skin as ceramides, hyaluronic acid, and panthenol deeply hydrate and support barrier repair, effectively addressing dryness and flakiness.
- Allantoin and glycerin further enhance the moisturizing and soothing effects, providing comprehensive comfort for your skin.
- The product is safe for your skin, containing no harsh ingredients and featuring a blend of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/oily-acne-prone-skin): High

## Key ingredients

Ceramides, Hyaluronic Acid, Glycerin, Phytosphingosine, Cholesterol

## What the research says

- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Application of Body Lotion for 5 weeks on cosmetic dry skin improved barrier properties, increased levels of cholesterol, ceramides, and long-chain fatty acids, increased beneficial skin bacteria, and enhanced microbiome functional potential compared to baseline. ([Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of an emulsion containing a complete mixture of ceramides III, IIIB, VI, phytosphingosine, cholesterol, and linoleic acid significantly accelerated barrier recovery after SLS damage and improved skin hydration after acetone treatment in human volunteers compared to an emulsion containing only two types of ceramides. ([Journal of the European Academy of Dermatology and Venereology, 2002](https://pubmed.ncbi.nlm.nih.gov/12482041/))
- Phytosphingosine demonstrates anti-microbial and anti-inflammatory activity with excellent clinical results in acne vulgaris. ([International Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/18489348/))
- Phytosphingosine increased filaggrin metabolism and skin hydration in human skin by stimulating filaggrin biosynthesis and degradation leading to natural moisturizing factor formation. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28936777/))
- Botulinum toxin-A encapsulated in phosphatidylcholine/cholesterol nanoliposomes delivered transdermally achieved a diffusion depth of 380 μm and showed a nonsignificant advantage in relieving post-acne scarring compared to hyaluronic acid hydrogel treatment in 12 facial patients. ([Journal of Materials Science. Materials in Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/39073502/))
- Topical application of cholesterol sulfate increases stratum corneum thickness and inhibits protease-induced cell dissociation by competitively inhibiting serine proteases in mice and human stratum corneum. ([The Journal of Investigative Dermatology, 1998](https://pubmed.ncbi.nlm.nih.gov/9699715/))
- Topical lovastatin treatment impairs the recovery of cutaneous permeability barrier function and stratum corneum cholesterol levels after acetone disruption in mice, an effect normalized by simultaneous treatment with mevalonate or cholesterol. ([The Journal of Clinical Investigation, 1990](https://pubmed.ncbi.nlm.nih.gov/2243142/))

## What reviewers say

Users with dry, sensitive, and combination skin praise this serum for its ability to repair the moisture barrier and calm redness without causing irritation. The lightweight, fragrance-free formula is frequently noted for improving skin texture and providing long-lasting hydration, though some users with oily skin find it leaves a slight tackiness.

- Liked: Lightweight & non-greasy (mostly mentioned)
- Liked: Effective hydration (often mentioned)
- Liked: Soothing & gentle (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Disliked: Price vs. size (sometimes noted)
- Disliked: Insufficient for very dry (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Slight tackiness (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Cetaphil Ceramide Serum a great fit for dry sensitive skin?

Cetaphil Ceramide Serum is a great fit because its ceramides, hyaluronic acid, and panthenol deeply hydrate and support barrier repair to tackle dryness and flakiness. Allantoin and glycerin add extra soothing comfort, and the gentle formula contains no harsh ingredients to keep sensitive skin safe.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Ceramides, hyaluronic acid, and panthenol make this serum a great fit because they deeply hydrate your skin and repair its natural barrier, while glycerin and allantoin soothe dryness and flakiness.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What do Ceramides do for dry sensitive skin?

Ceramides help strengthen dry, sensitive skin by locking in moisture and repairing the outer barrier, which makes skin feel softer and less irritated. This type of care helps prevent dryness and keeps skin calm and comfortable.
Sources: [The British Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34921679/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39492723/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in the evening routine after cleansing and toning, and before moisturizing. Putting it in the evening helps keep things simple and safe around sun exposure while providing deep hydration and barrier repair.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to help calm and hydrate your skin before applying retinol. Using a barrier-supporting product helps reduce dryness and irritation while you use retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

You can use this serum in your evening routine as part of your daily skincare steps. Daily application helps keep your dry and sensitive skin deeply hydrated and supports your skin barrier.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts on dry sensitive skin, as it contains no harsh ingredients and features a blend of gentle, soothing components that help keep skin calm and smooth.

### Can I use this serum around the eyes or on my body?

Yes, you can use this serum around the eyes and on your body because its gentle blend of ceramides, hyaluronic acid, and panthenol deeply hydrates and repairs the skin barrier. These ingredients are well-suited to help relieve dryness and flakiness on thinner areas like the eyelids as well as larger areas of the body.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €9.19 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/dry-sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/it/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €20.40 at Amazon

## Where to buy

- Amazon.it: €35.67 (https://www.amazon.it/dp/B0CZD72G5W?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Cetearyl Alcohol, Ceteareth-20, Ceramide Np, Ceramide Ap, Ceramide Eop, Phytosphingosine, Cholesterol, Hyaluronic Acid, Tocopheryl Acetate, Panthenol, Allantoin, Xanthan Gum, Carbomer, Disodium Edta, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/cetaphil/ceramide-serum/for/dry-sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cetaphil/ceramide-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cetaphil/ceramide-serum/for/dry-sensitive-skin