# celimax The Real Cica Calming Ampoule for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [celimax](https://lovi.care/skincare/it/brands/celimax)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for dry skin.

## Why this fit

- Excellent suitability for your dry skin is provided by Centella Asiatica Extract and Madecassoside, which offer superb barrier repair and humectant action to combat dryness and flakiness.
- Panthenol and Hydroxyethyl Urea further enhance hydration and soothe irritation, supporting overall skin comfort.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/oily-acne-prone-skin): Superior

## Key ingredients

Centella Asiatica Extract, Madecassoside, Sodium Hyaluronate, Allantoin, Beta-Glucan

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))

## What reviewers say

This ampoule is highly regarded for its ability to calm sensitive and acne-prone skin, effectively reducing redness and irritation. Its lightweight, non-sticky texture is particularly favored by those with oily and combination skin, providing fresh hydration. However, individuals with dry skin may find it necessary to layer with a richer moisturizer for adequate hydration, especially in colder months.

- Liked: Soothing and calming (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Sensitive skin friendly (often mentioned)
- Liked: Acne and blemish care (sometimes noted)
- Disliked: Dry skin hydration (sometimes noted)
- Disliked: Mild stickiness (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Small size (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes celimax The Real Cica Calming Ampoule a great fit for dry skin?

This product is a great fit because Centella Asiatica Extract and Madecassoside help repair your skin barrier and hold onto moisture to fight off dryness and flakiness. Panthenol and Hydroxyethyl Urea further boost hydration and calm irritation, making it very comfortable for dry skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this serum a good fit for dry skin?

Centella Asiatica Extract and Madecassoside are a great fit for your dry skin because they repair the skin barrier and draw in moisture to fight flakiness. Panthenol and Sodium Hyaluronate further boost hydration and soothe irritation to keep your skin soft and comfortable.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Centella Asiatica Extract do for dry skin?

Centella asiatica extract helps dry skin by boosting moisture and reducing water loss while calming irritation. It supports barrier repair to keep the skin feeling soft and smooth.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Madecassoside do for dry skin?

Madecassoside helps dry skin by boosting moisture and supporting the skin barrier so it holds onto water better. It also calms irritation and protects skin cells from everyday damage.
Sources: [Bioscience, Biotechnology, and Biochemistry, 2019](https://pubmed.ncbi.nlm.nih.gov/30452312/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Putting it in the evening helps keep things simple and gives extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying it right before your moisturizer in your evening routine. This helps soothe the skin and keeps it hydrated while using active ingredients, and it is unlikely to cause irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

This serum is used in your evening routine, applying it after cleansing and before moisturizing. You may use it every evening to help soothe dryness and boost skin comfort.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is a great fit for your dry skin and is unlikely to clog pores or cause breakouts because it leaves out harsh ingredients and includes soothing components. It helps combat dryness and flakiness while keeping your skin calm.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [SKIN1004 Madagascar Centella Asiatica Ampoule](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-asiatica-ampoule/for/dry-skin) — High fit — €18.99 at Amazon
- [Purito Galacto Niacin 97 Power Essence](https://lovi.care/skincare/it/p/purito/galacto-niacin-97-power-essence/for/dry-skin) — High fit — €18.95 at Amazon
- [Clarins Double Serum](https://lovi.care/skincare/it/p/clarins/double-serum/for/dry-skin) — Average fit — €109.25 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €9.19 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — €15.16 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/it/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-skin) — Superior fit — €53.50 at Amazon

## Where to buy

- Notino: €24.20 (https://www.notino.it/celimax/the-real-cica-niacinamide-ac-calming-serum-siero-lenitivo-per-pelli-sensibili-con-tendenza-allacne/p-16281157/)
Prices checked 10 Oct 2026.

## Ingredients

Centella Asiatica Extract, Water, Dipropylene Glycol, 1,2-Hexanediol, Butylene Glycol, Hydroxyethyl Urea, Glycerin, Polyglyceryl-10 Myristate, Carbomer, Tromethamine, Hydroxyacetophenone, Caprylyl Glycol, Ethylhexylglycerin, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Allantoin, Disodium Edta, Madecassoside, Portulaca Oleracea Extract, Glyceryl Acrylate Acrylic Acid Copolymer, Trehalose, Panthenol, Pvm Ma Copolymer, Beta-Glucan, Biosaccharide Gum-1, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Asiaticoside, Asiatic Acid, Madecassic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- France: https://lovi.care/skincare/fr/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/celimax/the-real-cica-calming-ampoule/for/dry-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/celimax/the-real-cica-calming-ampoule/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/celimax/the-real-cica-calming-ampoule/for/dry-skin