# Biossance Squalane + Probiotic Gel Moisturizer for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Biossance](https://lovi.care/skincare/it/brands/biossance)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few moisturizers fit it even better.

## Why this fit

- Offers excellent moisturizing for your combination skin, as squalane and glycerin hydrate and enhance barrier resilience without overwhelming oily areas.
- Lactococcus lysate ferment and squalane provide moderate benefits for oily shine by supporting skin barrier function.
- The formulation is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/oily-acne-prone-skin): High

## Key ingredients

Squalane, Probiotics, Glycerin, Lactococcus Lysate Ferment, Zingiber Officinale Root Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- A 1-year clinical study on human facial skin demonstrated that Zingiber officinale (L.) Rose extract inhibits the UV-induced decrease in skin elasticity and prevents or improves wrinkle formation around the eye. ([Archives of Dermatological Research, 2008](https://pubmed.ncbi.nlm.nih.gov/17968573/))
- Ginger extract transethosomal hydrogel improved skin permeability, sustained drug release, and exhibited significant inhibition of edema swelling along with reduced reactive oxygen species and prostaglandin E2 compared to free ginger extract hydrogel and ketoprofen gel in a rat-paw edema model. ([International Journal of Nanomedicine, 2023](https://pubmed.ncbi.nlm.nih.gov/36945254/))
- Topical delivery of ginger extract-loaded nanoemulsions significantly reduced arthritic symptoms, paw edema inhibition by 27.7%, and inflammatory cytokines in RA-induced rats compared to the negative control. ([Journal of Pharmaceutical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/36773928/))

## What reviewers say

Based on a very large amount of data, this lightweight gel moisturizer is highly recommended for oily, combination, and sensitive skin types, effectively hydrating without pore clogging and visibly reducing redness. However, a significant number of recent reviews indicate dissatisfaction with a formula change, noting a stickier texture and less pleasant scent compared to the original. Dry skin types may find it insufficient for hydration, and some users express concerns about the price point. A small number of users have reported irritation or breakouts.

- Liked: Lightweight & fast absorbing (mostly mentioned)
- Liked: Balances oily skin (often mentioned)
- Liked: Calms redness & irritation (often mentioned)
- Disliked: Reformulation complaints (often mentioned)
- Liked: Excellent makeup base (sometimes noted)
- Disliked: Not hydrating enough (sometimes noted)
- Disliked: Price point (sometimes noted)
- Disliked: Irritation and breakouts (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Biossance Squalane + Probiotic Gel Moisturizer a great fit for combination skin?

Biossance Squalane + Probiotic Gel Moisturizer is a great fit because squalane and glycerin hydrate dry patches and strengthen your barrier without overwhelming oily areas. Lactococcus lysate ferment and squalane also help manage oily shine by supporting overall skin health, and the gentle formula is very unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this moisturizer a good fit for combination skin?

Squalane and glycerin make this moisturizer a great fit for combination skin because they hydrate and strengthen the skin barrier without feeling too heavy on oily areas. Lactococcus lysate ferment and squalane also help manage oily shine by supporting the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Squalane do for combination skin?

Squalane helps keep combination skin soft and smooth by locking in moisture without feeling heavy or greasy. It supports the skin barrier and provides lightweight hydration that works well for both dry and oily areas.
Sources: [Skin Health and Disease, 2024](https://pubmed.ncbi.nlm.nih.gov/39355739/), [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/)

### What do Probiotics do for combination skin?

Probiotics help keep combination skin calm and balanced by supporting the skin barrier and reducing irritation across oily and dry areas. They may also improve skin moisture while helping to keep pores clear and skin smooth.
Sources: [International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/), [Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31021014/)

### Where does this moisturizer go in a skincare routine for combination skin?

This moisturizer goes as the last step of your morning routine before sunscreen and after your treatment in the evening routine. Applying it then helps lock in hydration and support your skin barrier without feeling too heavy on oily areas.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this moisturizer with retinol, and in what order?

You can use this moisturizer with retinol by applying the retinol first, letting it absorb, and then following with the moisturizer. This routine helps keep your combination skin calm and hydrated while reducing the dryness and irritation often caused by retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this moisturizer?

This moisturizer is a great fit for your combination skin and can be used daily as part of your morning and evening routine. Squalane and glycerin hydrate your skin while helping control oily shine without feeling heavy.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this moisturizer clog pores, cause breakouts or purging for combination skin?

This moisturizer is a great fit for your combination skin and is unlikely to cause irritation or breakouts because it is free of harsh ingredients. Squalane and glycerin hydrate dry patches while keeping oily areas clear, and the safe formula minimizes the risk of clogged pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this moisturizer around the eyes or on my body?

You can use this moisturizing treatment on the thin skin around the eyes and on your body, as its gentle ingredients are well tolerated by delicate areas. Clinical studies show that applying nourishing creams to periorbital and body regions is safe and helps improve skin texture without irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [European Journal of Pharmaceutics and Biopharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/24056055/)

### Is this moisturizer fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — €18.06 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/it/p/drunk-elephant/protini-polypeptide-cream/for/combination-skin) — Superior fit — €92.92 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/it/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — €13.11 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €13.50 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — €103.91 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — €40.49 at Amazon

## Where to buy

- Lookfantastic: €31.05 (https://www.lookfantastic.it/p/biossance-probiotic-bottle-pump-50ml-fs-fg/17625977/)
Prices checked 17 Oct 2026.

## Ingredients

Water, Squalane, Glycerin, Dimethicone, Pentylene Glycol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Lactococcus Lysate Ferment, Caprylic Capric Triglyceride, Phenoxyethanol, Caprylyl Glycol, Dimethiconol, Chondrus Crispus Extract, Allantoin, Bisabolol, Glycine Soja Soybean Sterols, Linoleic Acid, Sodium Phytate, Lecithin, Sodium Hydroxide, Sodium Hyaluronate, Lactic Acid, Lepidium Sativum Extract Sprout, Sodium Chloride, Sodium Benzoate, Citric Acid, Zingiber Officinale Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- France: https://lovi.care/skincare/fr/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/biossance/squalane-probiotic-gel-moisturizer/for/combination-skin