Biossance Squalane + Lactic Acid Resurfacing Night Serum for mature skin
Squalane
Lactic Acid
Glycerin
Lavender Oil
Acacia Senegal GumAverage
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for mature skin; other products fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate exfoliation for your normal skin due to lactic acid, which helps regulate desquamation and smooth texture, while squalane provides emollient action.
- While the formula is safe and hydrating for your normal skin, the concentration of lactic acid is not significant enough to provide substantial resurfacing for your wrinkles and fine lines.
- The product is safe for your normal skin, with squalane offering soothing benefits and no harsh ingredients present.
How to apply
- Use this exfoliant product in your PM routine once a week to start, increasing frequency only if your skin tolerates it well. Always apply SPF the next morning to protect your skin.
- Apply this exfoliant product after cleansing and toner, but before your moisturizer. This ensures the best absorption into your skin.
- Gently press 2-3 drops of the exfoliant product into your face, avoiding any rubbing. Let it absorb for a minute before moving to the next step.
- Apply this exfoliant product on completely dry skin to get the best results. This helps your normal skin accept the product smoothly.
- Avoid the sensitive eye area while using this exfoliant product. Do a patch test before your first use and avoid mixing it with strong acids.
People Say
★4.6Overall rating based on 2.8k+ reviewsBased on a very large amount of data, this serum is highly effective at smoothing rough texture and brightening dull skin, often overnight, without causing dryness. Most users, including those with sensitive skin, find it gentle and hydrating. A moderate number of users dislike the herbal scent and find the product expensive, while a low number report experiencing irritation or breakouts.
Highlights
Smoothes skin texture Mostly Mentioned
- “smooths out rough skin”
- “baby soft results”
- “bumps are gone”
- “refined my texture”
Brightens complexion Often Mentioned
- “woke up glowing”
- “skin looks luminous”
- “radiant next morning”
- “removed dullness”
Gentle and hydrating Often Mentioned
- “no irritation at all”
- “didn't dry me out”
- “great for sensitive skin”
- “moisturizing feel”
Fades dark spots Sometimes Noted
- “acne scars faded”
- “helped with pigmentation”
- “evened skin tone”
- “spots look lighter”
Herbal scent disliked Sometimes Noted
- “smells a bit funny”
- “strong lavender scent”
- “off-putting smell”
- “scent is weird”
High price point Sometimes Noted
- “very expensive”
- “pricey for the size”
- “wish it was cheaper”
- “investment product”
Caused breakouts Rarely Noted
- “broke me out”
- “caused tiny bumps”
- “purging period”
- “woke up with zits”
Causes irritation Rarely Noted
- “burned my face”
- “caused red blotches”
- “stings upon application”
- “too strong for me”
Sources: lovi.care, biossance.com, sephora.com, influenster.com, cultbeauty.co.uk, makeupalley.com, and more
Questions and answers
How well does Biossance Squalane + Lactic Acid Resurfacing Night Serum work for mature skin?
Biossance Squalane + Lactic Acid Resurfacing Night Serum works moderately well for mature skin, providing gentle smoothing and hydration, but the lactic acid concentration is not significant enough to substantially target fine lines and wrinkles. Mature skin needs an exceptionally safe product that effectively targets wrinkles with high-quality anti-aging ingredients, rich in antioxidants, peptides, and humectants to improve elasticity and moisture retention.
Which ingredients make this serum a good fit for mature skin?
Lactic acid and squalane make this serum a fit for mature skin by helping smooth texture and keep it soft with moisture. Because this product is an average fit, an exfoliant treatment for mature skin needs powerful anti-aging ingredients like high-quality antioxidants, peptides, and humectants to effectively target fine lines and improve elasticity.
What does Squalane do for mature skin?
Squalane helps keep mature skin feeling soft and smooth by boosting moisture and protecting the skin barrier. It also provides antioxidant support that helps improve the look of fine lines and wrinkles over time.
Journal of Nanobiotechnology, 2025Journal of Nanoscience and Nanotechnology, 2010
What does Lactic Acid do for mature skin?
Lactic acid helps mature skin by boosting firmness and smoothing out rough texture through increased collagen production. It also helps lock in moisture and brightens dark spots for a more youthful appearance.
International Journal of Biological Macromolecules, 2024Frontiers in Medicine, 2021
Where does this serum go in a skincare routine for mature skin?
This serum goes in the evening routine after cleansing and before moisturizing, starting once a week and using it more often if tolerated well. Mature skin needs stronger treatments with higher concentrations of active ingredients like lactic acid to effectively smooth fine lines and wrinkles.
Can I use this serum with retinol, and in what order?
This serum is safe to use on your mature skin, but layering it with a strong retinol may easily cause irritation. When using both in the evening, apply this lactic acid treatment first, let it absorb, and follow with your moisturizer before adding a retinol on alternate nights.
How often should I use this serum?
Start by using this treatment once a week in your evening routine, and carefully increase the frequency if your skin tolerates it well and sees good results.
Can this serum clog pores, cause breakouts or purging for mature skin?
This serum is unlikely to cause breakouts or clog pores on mature skin since it has a safe formula with low user complaints and soothing squalane. However, because it contains lactic acid, it may cause mild skin clearing or irritation when you first start using it.
Is this serum fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.
What the research says
Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate.
Scientific Reports, 2020Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Application of squalene/phosphotungstate calcium nanowires (Sql/PWC) oleogel on UVB-irradiated skin decreased epidermal thickness, increased dermal thickness, and promoted the expression of elastin, collagen, and skin barrier markers through antioxidant and anti-inflammatory activities.
Journal of Nanobiotechnology, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin.
Cutis, 2004Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties.
Journal of the American Academy of Dermatology, 1992A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins.
The Journal of Clinical and Aesthetic Dermatology, 2020A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Polysaccharide-based O/W emulsions incorporated with lavender essential oil applied to cellulosic support are non-irritating, provide softness and moisturizing effects, and are safe for topical patch applications.
International Journal of Biological Macromolecules, 2021Gellan gum hydrogel films co-encapsulating ofloxacin with tea tree or lavender oil achieved 98% wound contraction and completely healed epidermis in rats after ten days of treatment compared to baseline.
International Journal of Biological Macromolecules, 2021Topical application of lavender oil significantly promoted wound contraction, collagen synthesis, and fibroblast differentiation with up-regulation of TGF-beta in a rat model compared to control.
BMC Complementary and Alternative Medicine, 2016Acacia gum and carbopol hydrogel wound dressings containing gentamicin showed faster wound healing, well-developed fibroblasts, and blood capillaries compared to open wounds in swiss albino mice.
International Journal of Pharmaceutics, 2013Barley beta-glucan films formulated with sorbitol and acacia gum demonstrated suitable mechanical properties and stimulated in vitro keratinocytes growth.
International Journal of Pharmaceutics, 2023Gum arabic and beta-cyclodextrin microencapsulated peony seed oil emulsion protected against ultraviolet radiation by inhibiting reactive oxygen species generation, increasing cell viability from 54.75% to 92.69% in UVB-damaged HaCaT cells, and repairing 95.56% of UVB-damaged skin within 7 days in animal experiments through regulation of the NF-kappaB signaling pathway.
International Journal of Biological Macromolecules, 2026
Why other products fit mature skin better
Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline.
In Vivo, 2023Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020
Ingredients
Acacia Senegal Gum, Caprylic Capric Triglyceride, Cetearyl Alcohol, Cetearyl Olivate, Ethylhexylglycerin, Glycerin, Lactic Acid, Lavandula Angustifolia Oil Lavender Oil, Lespedeza Capitata Stem Extract Leaf, Linalool, Phenoxyethanol, Polyacrylate Crosspolymer-6, Propanediol, Sodium Gluconate, Sodium Hydroxide, Sorbitan Olivate, Squalane, Water, Xanthan Gum
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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