# APLB Glutathione Niacinamide Facial Cream for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [APLB](https://lovi.care/skincare/it/brands/aplb)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your dry and sensitive skin, this cream effectively hydrates and soothes with sodium hyaluronate and Centella Asiatica Extract, which replenish moisture and calm irritation.
- Glycerin and shea butter further enhance its emollient properties, providing lasting comfort and smoothness for dry or flaky skin.
- The formulation is safe for your skin, containing no harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/oily-acne-prone-skin): High

## Key ingredients

Glutathione, Niacinamide, Centella Asiatica Extract, Sodium Hyaluronate, Shea Butter

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))

## What reviewers say

Based on a very large amount of data, this lightweight, gel-like cream is highly favored by users with oily, combination, and sensitive skin for its fast absorption and soothing properties without leaving a sticky residue. Many appreciate its ability to calm redness and improve skin texture. However, users with dry skin often find it insufficiently moisturizing on its own, and brightening effects tend to be gradual or subtle.

- Liked: Affordable value (often mentioned)
- Liked: Fragrance-free (often mentioned)
- Liked: Lightweight & fast (often mentioned)
- Liked: Soothing & calming (often mentioned)
- Disliked: Not for dry skin (often mentioned)
- Disliked: No spatula (rarely noted)
- Disliked: Packaging concerns (rarely noted)
- Disliked: Slow brightening (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes APLB Glutathione Niacinamide Facial Cream a great fit for dry sensitive skin?

This cream is a great fit because it uses sodium hyaluronate and Centella Asiatica Extract to replenish moisture and calm irritation. Glycerin and shea butter further provide lasting comfort and smoothness for dry skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for dry sensitive skin?

This cream is a great fit because sodium hyaluronate and Centella Asiatica Extract replenish lost moisture and calm irritation. Glycerin and shea butter further enhance comfort by leaving dry and flaky skin soft and smooth.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glutathione do for dry sensitive skin?

Glutathione helps improve moisture content and smoothness while reducing oxidative stress, making it a helpful option for dry sensitive skin. This ingredient may enhance hydration and elasticity while maintaining a gentle profile. To properly care for dry sensitive skin, a product of this type needs soothing and hydrating ingredients that support the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This moisturizing treatment goes in your evening routine as a treatment step before your moisturizer, or you can use it in your morning routine if your skin needs extra comfort. It is a great fit for your dry sensitive skin because it helps replenish moisture and calm irritation with sodium hyaluronate and Centella Asiatica Extract.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying it after your retinol treatment to help calm the skin and lock in moisture. Using a gentle moisturizer alongside retinol is unlikely to cause irritation and helps keep dry skin smooth and comfortable.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

This cream is a great fit for your dry sensitive skin and can be used daily in your evening routine. Daily application helps boost skin moisture, calm irritation, and keep flaky skin feeling soft and smooth.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to clog pores or cause breakouts on dry sensitive skin because it is free of harsh ingredients and uses calming components like Centella Asiatica Extract to keep skin comfortable without heavy residue.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream around the eyes or on my body?

Yes, you can use this moisturizing treatment around the eyes and on the body because its gentle formula provides safe and lasting comfort for dry or flaky skin. Clinical studies show that regular application of creams with hydrating and botanical ingredients improves skin moisture and reduces fine lines around the eyes without causing irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/it/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-sensitive-skin) — Superior fit — €13.11 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/dry-sensitive-skin) — Superior fit — €18.06 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/it/p/l-occitane/immortelle-divine-cream/for/dry-sensitive-skin) — Superior fit — €82.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €9.19 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/dry-sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/it/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €20.40 at Amazon

## Where to buy

- Amazon.it: €8.24 (https://www.amazon.it/dp/B0C2P3N623?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Centella Asiatica Extract, Glycerin, Cetyl Ethylhexanoate, Butylene Glycol, Polyglyceryl-3 Methylglucose Distearate, Stearic Acid, Sodium Polyacryloyldimethyl Taurate, Silica, Sodium Hyaluronate, Glyceryl Stearate, Beeswax, Butyrospermum Parkii Butter Shea Butter, Macadamia Ternifolia Seed Oil, Hydrogenated Polydecene, Betaine, Trehalose, Adenosine, Citric Acid, Trideceth-10, Disodium Edta, Sodium Citrate, Caprylic Capric Triglyceride, Hydrogenated Lecithin, Cholesterol, Xanthan Gum, Nelumbo Nucifera Extract, Artemisia Annua Extract, Rice Extract, Saccharomyces Ferment, Solanum Melongena Fruit Extract, Melaleuca Alternifolia Tree Leaf Extract, Hydrolyzed Collagen, Squalane, Beta-Glucan, Ascorbic Acid, Dipropylene Glycol, Hippophae Rhamnoides Fruit Extract, Madecassic Acid, Asiaticoside, Asiatic Acid, Propanediol, Hydroxyacetophenone, 1,2-Hexanediol, Ethylhexylglycerin, Dipotassium Glycyrrhizate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/aplb/glutathione-niacinamide-facial-cream/for/dry-sensitive-skin