# APLB Collagen EGF Peptide Ampoule Serum for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [APLB](https://lovi.care/skincare/it/brands/aplb)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this serum effectively addresses redness and irritation with niacinamide and beta-glucan, which offer soothing and anti-inflammatory benefits.
- The inclusion of hydrolyzed collagen, Rh-Oligopeptide-1, and Palmitoyl Pentapeptide-4 provides excellent skin firming and wrinkle reduction, further enhancing your skin's overall health.
- The product is safe for your sensitive skin, as it lacks harsh ingredients and contains soothing components like niacinamide and beta-glucan.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/oily-acne-prone-skin): High

## Key ingredients

Collagen, Rh-Oligopeptide-1, Peptides

## What the research says

- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Topical palmitoyl pentapeptide (pal-KTTKS) provided significant improvement versus placebo control in the reduction of wrinkles and fine lines in Caucasian female subjects. ([International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/))
- Combined therapy using a topical hyaluronic acid-niacinamide-Matrixyl serum and a multimodal facial device decreased TruSkin age by five years and reduced wrinkles more effectively than the serum alone in a 41-year-old woman with moderate facial aging over 12 weeks. ([Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42500768/))
- A functionalized dendrimer nanocarrier delivers active ingredients into the dermis and enhances collagen production in human dermal fibroblasts by co-delivering all-trans retinol and palmitoyl pentapeptide-4. ([Acta Biomaterialia, 2025](https://pubmed.ncbi.nlm.nih.gov/39694719/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone. ([The New England Journal of Medicine, 1989](https://pubmed.ncbi.nlm.nih.gov/2659995/))
- Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba. ([Lasers in Surgery and Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/30614013/))
- Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars. ([The Journal of Clinical and Aesthetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35942017/))

## What reviewers say

Based on limited data, users with dry, sensitive, and aging skin frequently report noticeable improvements in hydration and skin plumpness, often describing a "bouncy" or firming effect. The fragrance-free formula is widely praised for being gentle and absorbing well, though a minority of users find the texture slightly tacky or report that anti-aging results are subtle.

- Liked: Fast absorption (often mentioned)
- Liked: Hydration & Plumping (often mentioned)
- Liked: Excellent value (sometimes noted)
- Liked: Fragrance-free (sometimes noted)
- Liked: Soothing & Gentle (sometimes noted)
- Disliked: Average results (rarely noted)
- Disliked: Tacky finish (rarely noted)
- Disliked: Thick consistency (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes APLB Collagen EGF Peptide Ampoule Serum a great fit for sensitive skin?

APLB Collagen EGF Peptide Ampoule Serum is a great fit because it lacks harsh ingredients and uses soothing components like niacinamide and beta-glucan to calm redness and irritation. It also includes collagen and peptides that firm the skin and reduce wrinkles while keeping your sensitive skin safe and comfortable.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it contains niacinamide and beta-glucan, which help calm redness and irritation without harsh ingredients. It is also packed with collagen and peptides that firm the skin and smooth out fine lines.
Sources: [Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42500768/)

### What does Collagen do for sensitive skin?

Collagen helps soothe sensitive skin by reducing dryness, redness, and rough patches while keeping moisture locked in. It improves the skin barrier so it is less easily irritated, and studies show it is well tolerated and safe for sensitive skin types.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19496838/), [Pharmaceutical Development and Technology, 2014](https://pubmed.ncbi.nlm.nih.gov/23675949/)

### What does EGF do for sensitive skin?

EGF helps calm sensitive skin by supporting barrier recovery and reducing moisture loss after irritation. It also helps protect skin cells from environmental damage and lowers inflammation to keep your face feeling soft and smooth.
Sources: [Skin Pharmacology and Physiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23108135/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine after your toner and before your moisturizer. Placing treatments in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to calm your skin, and following with retinol once it absorbs. This helps keep your skin comfortable while you use both active products.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

This serum is a great fit for your sensitive skin and is meant to be used in the evening routine. It lacks harsh ingredients and includes soothing components like niacinamide and beta-glucan, making it safe for regular evening use.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts on sensitive skin. It leaves out harsh ingredients and includes soothing components like niacinamide and beta-glucan to keep the skin calm.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €129.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.10 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/it/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €17.59 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/it/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €19.21 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Butylene Glycol, Niacinamide, Hydrolyzed Collagen, Rh-Oligopeptide-1, Palmitoyl Pentapeptide-4, Sodium Hyaluronate, Beta-Glucan, Adenosine, Allantoin, Panthenol, Tocopheryl Acetate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
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- Saudi Arabia: https://lovi.care/skincare/sa/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin