# Anua PDRN Hyaluronic Acid Capsule 100 Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Anua](https://lovi.care/skincare/it/brands/anua)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your oily skin due to the presence of niacinamide, which offers seboregulation and barrier repair benefits, while multiple forms of hyaluronic acid provide excellent deep hydration and improve skin elasticity.
- It offers general hydration benefits for your oily skin, but lacks targeted ingredients like salicylic acid or retinoids to effectively address your concerns of acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Hydrolyzed Hyaluronic Acid, Niacinamide, Glutathione

## What the research says

- Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35775872/))
- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))

## What reviewers say

Users consistently praise this serum for delivering the coveted "glass skin" look, offering deep hydration that plumps the skin without feeling heavy or greasy. While most find it excellent for barrier repair and instant glow, a minority feel it is simply a good hydrator rather than a "life-changing" treatment for the price.

- Liked: Deep hydration (mostly mentioned)
- Liked: Glass skin glow (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Makeup compatibility (sometimes noted)
- Liked: Soothing & repair (sometimes noted)
- Disliked: Price vs volume (sometimes noted)
- Disliked: Breakouts (rarely noted)
- Disliked: Runny consistency (rarely noted)
- Disliked: Subtle results (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Anua PDRN Hyaluronic Acid Capsule 100 Serum a great fit for oily acne-prone skin?

This serum is a great fit for your oily skin because niacinamide helps balance oil and repair your skin barrier, while multiple forms of hyaluronic acid provide deep hydration without feeling heavy. It is also very safe and unlikely to cause irritation.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide makes this serum a great fit for your oily skin because it helps balance oil and repair your skin barrier, while multiple forms of hyaluronic acid provide deep hydration without feeling heavy. It is unlikely to cause irritation since it leaves out harsh ingredients, though it lacks targeted acne fighters like salicylic acid.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### What does Hydrolyzed Hyaluronic Acid do for oily acne-prone skin?

Hydrolyzed Hyaluronic Acid helps hydrate oily acne-prone skin without clogging pores, keeping it soft and smooth. It is generally well tolerated and unlikely to cause irritation when used daily.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### Where does it go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing, which keeps the routine simple and safe around sun exposure. Its niacinamide helps balance oil and repair the skin barrier, while multiple forms of hyaluronic acid give your oily skin deep hydration without irritation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35775872/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, applying the serum before your retinol product to help keep your oily skin hydrated and calm. It has an excellent safety profile with no harsh ingredients, making it unlikely to cause irritation when paired with stronger treatments.

### How often should I use it?

You can use this treatment in the evening as part of your routine. It provides great deep hydration without irritation, but a routine for your skin also needs targeted ingredients like salicylic acid or retinoids to effectively address breakouts.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can it clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to cause irritation or clog pores on oily acne-prone skin because it has an excellent safety profile without harsh ingredients. However, it lacks targeted ingredients like salicylic acid or retinoids to actively prevent blemishes and breakouts.

### Can I use this serum around the eyes or on my body?

This serum is a great fit for your oily skin, but it is not specifically formulated for the delicate skin around the eyes or the body. You can use it safely on the face, though an eye-specific cream or a richer body lotion is generally needed to properly care for those areas.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/it/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — €21.00 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/it/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-acne-prone-skin) — High fit — €17.99 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/it/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/oily-acne-prone-skin) — High fit — €29.69 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/it/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/it/p/dear-klairs/supple-preparation-unscented-toner/for/oily-acne-prone-skin) — Superior fit — €18.16 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — €40.49 at Amazon

## Where to buy

- Amazon.it: €25.79 (https://www.amazon.it/dp/B0DSVF8HGZ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €18.40 (https://www.lookfantastic.it/p/anua-pdrn-hyaluronic-acid-capsule-100-serum-30ml/16674990/)
- Notino: €24.90 (https://www.notino.it/anua/pdrn-hyaluronic-acid-capsule-100-serum-siero-idratante-e-nutriente-con-collagene/p-16313399/)
Prices checked 10 Oct – 5 Nov 2026.

## Ingredients

Water, Butylene Glycol, Propanediol, Glycerin, Hydrolyzed Hyaluronic Acid, 1,2-Hexanediol, Niacinamide, Glyceryl Oleate, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Hydrogenated Lecithin, Glutathione, Hydrolyzed Collagen, Hyaluronic Acid, Coptis Japonica Root Extract, Adenosine, Sodium Dna, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Ocimum Sanctum Leaf Extract, Citric Acid, Curcuma Longa Root Extract, Corallina Officinalis Extract, Sodium Citrate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-acne-prone-skin
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