# Anua Heartleaf 78% Soothing Cream for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Anua](https://lovi.care/skincare/it/brands/anua)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few moisturizers fit it even better.

## Why this fit

- This product is highly suitable for your dry and sensitive skin, as the high concentration of Houttuynia Cordata Extract and Centella Asiatica Extract effectively calms irritation and provides deep hydration. Phytosqualane and Beta-Glucan further support your skin's hydration and barrier function, addressing dryness and flakiness.
- The inclusion of Hydrolyzed Hyaluronic Acid offers targeted moisturization, enhancing the product's benefits for your specific skin concerns.
- The formulation is safe for your skin, with no harsh ingredients and a good balance of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/oily-acne-prone-skin): High

## Key ingredients

Heartleaf Extract, Centella Asiatica Extract, Allantoin, Jojoba Oil, Hydrolyzed Hyaluronic Acid

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Application of fullerene-C60 dissolved in squalane cream twice daily for 8 weeks significantly enhanced skin moisture and reduced wrinkle formation compared to placebo in 23 Japanese women without severe side effects. ([Journal of Nanoscience and Nanotechnology, 2010](https://pubmed.ncbi.nlm.nih.gov/21137794/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Clay jojoba oil facial masks reduced total skin lesions by a mean of 54% after 6 weeks in 133 participants with acne-prone, lesioned skin and mild acne compared to baseline. ([Forschende Komplementarmedizin, 2012](https://pubmed.ncbi.nlm.nih.gov/22585103/))
- Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model. ([Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/))
- Topical jojoba oil application in male mice decreased exercise-induced pro-inflammatory gene expression (Il-1b and Il-6 in soleus, Il-1b in gastrocnemius) compared to untreated exercised mice. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/41154623/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on limited data, users find this cream to be a lightweight, gel-like moisturizer that effectively calms redness and cools the skin, making it suitable for oily, acne-prone, and sensitive skin types. However, individuals with dry or dehydrated skin often report it is not hydrating enough on its own.

- Liked: Soothing & calming (mostly mentioned)
- Liked: Lightweight gel texture (often mentioned)
- Disliked: Insufficient hydration (often mentioned)
- Liked: Cooling effect (sometimes noted)
- Liked: Safe for sensitive/acne skin (sometimes noted)
- Disliked: Cooling discomfort (rarely noted)
- Disliked: Scent/smell (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Anua Heartleaf 78% Soothing Cream a great fit for dry sensitive skin?

Anua Heartleaf 78% Soothing Cream is a great fit because it uses heartleaf and centella asiatica extracts to calm irritation while deeply hydrating dry skin. It also includes phytosqualane, beta-glucan, and hyaluronic acid to help lock in moisture and keep your skin soft and comfortable.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)

### Which ingredients make this cream a good fit for dry sensitive skin?

This cream is a great fit for your dry sensitive skin because heartleaf extract and centella asiatica extract calm irritation while deep hydration ingredients like phytosqualane, beta-glucan, and hydrolyzed hyaluronic acid help ease dryness and flakiness. The formula is safe for your skin with a good balance of soothing components and no harsh ingredients.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Nanoscience and Nanotechnology, 2010](https://pubmed.ncbi.nlm.nih.gov/21137794/)

### What does Heartleaf Extract do for dry sensitive skin?

Heartleaf Extract helps calm dry sensitive skin by reducing irritation and supporting the skin barrier. It is unlikely to cause trouble and may help keep your skin feeling soft and smooth.
Sources: [International Journal of Biological Macromolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40393586/)

### What does Centella Asiatica Extract do for dry sensitive skin?

Centella asiatica extract helps calm dry sensitive skin by reducing irritation and improving moisture while protecting the skin barrier. Clinical studies show that regular use noticeably decreases redness and discomfort while keeping the skin soft and hydrated.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This cream goes in your evening routine as a treatment step before your moisturizer, or you can use it whenever your skin needs extra calming and hydration. Its soothing ingredients help reduce irritation and keep dry skin soft and comfortable.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying it after your retinol treatment to help calm irritation and add moisture. Using a gentle, barrier-supporting moisturizer alongside retinol helps reduce dryness and flakiness while keeping your skin soft.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

This moisturizing treatment is a great fit for your dry sensitive skin and helps keep it soft and calm when used daily in your evening routine. Regular application helps maintain moisture and supports your skin barrier without harsh ingredients.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to clog pores or cause breakouts for your dry sensitive skin, as it features a balanced blend of soothing and hydrating ingredients without heavy, pore-blocking components.

### Can I use this cream around the eyes or on my body?

This cream is well-suited for the thin skin around the eyes and on the body because its soothing and hydrating ingredients calm irritation and relieve dryness across delicate skin areas. Its gentle formula is unlikely to cause irritation and maintains good skin tolerance.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry sensitive skin

- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/it/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-sensitive-skin) — Superior fit — €13.11 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/it/p/l-occitane/immortelle-divine-cream/for/dry-sensitive-skin) — Superior fit — €82.99 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/it/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/dry-sensitive-skin) — Superior fit — €18.06 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €9.19 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/dry-sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/it/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €20.40 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Houttuynia Cordata Extract, Methylpropanediol, Propylheptyl Caprylate, Butylene Glycol, 1,2-Hexanediol, Polyglyceryl-6 Distearate, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Pumpkin Fruit Extract, Acmella Oleracea Extract, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate Vp Copolymer, Jojoba Esters, Xanthan Gum, Cetyl Alcohol, Polyglyceryl-3 Beeswax, Water, Phytosqualane, Panthenol, Menthyl Pca, Ethyl Menthane Carboxamide, Fructooligosaccharides, Beta-Glucan, Allantoin, Hydrolyzed Hyaluronic Acid, Glycine, Ceramide Np, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Valine, Proline, Isoleucine, Histidine, Cysteine, Methionine, Avena Sativa Kernel Flour Oat Kernel Flour, Silica, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin