# Advanced Clinicals HYALURONIC SERUM for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Advanced Clinicals](https://lovi.care/skincare/it/brands/advanced-clinicals)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/it/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your combination skin, as hyaluronic acid and glycerin provide hydration without exacerbating oily shine.
- The inclusion of Pyrus Malus Fruit Extract and Camellia Sinensis Leaf Extract offers antioxidant benefits, supporting overall skin health.
- The product is safe for your combination skin, with no harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Hyaluronic Acid, Glycerin, Aloe Barbadensis Leaf Juice

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- A cosmetic cream with 6% standardized wild apple fruit extract and a conventional emulsifier demonstrated stable antioxidant activity of 19.25 %RSC, increased skin moisturization, and a decreased melanin index by -31.40 without causing skin irritation. ([International Journal of Cosmetic Science, 2019](https://pubmed.ncbi.nlm.nih.gov/31050807/))
- Topical formulations containing 1.25% Malus sp. extract or 0.75% rutin protected against UVB-induced sunburn cells, caspase-3 activation, cyclobutane pyrimidine dimers, lipid peroxidation, and metalloproteinase formation in ex vivo skin explants and 3D tissue-engineered skin. ([Rejuvenation Research, 2020](https://pubmed.ncbi.nlm.nih.gov/32242497/))
- Dermocosmetic creams containing 6%, 12%, and 15% of standardized wild apple fruit ultrasonic extract increased skin hydration proportionally to extract concentration after 28 days of application on healthy volunteers without altering transepidermal water loss or skin pH. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35048513/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))

## What reviewers say

This serum is highly effective for providing instant and deep hydration, improving skin texture, and reducing the appearance of fine lines, making it a popular choice for dry, dehydrated, and aging skin types. Users frequently experience a plumper complexion and diminished fine lines. Some users note a slightly sticky finish or a strong fragrance.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Great value (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Liked: Absorbs quickly (sometimes noted)
- Disliked: Noticeable fragrance (sometimes noted)
- Disliked: Slightly sticky finish (sometimes noted)
- Disliked: Potential ingredient concerns (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Advanced Clinicals Hyaluronic Serum work for combination skin?

Advanced Clinicals Hyaluronic Serum works moderately well for combination skin by providing hydration without adding oily shine, though other options fit this skin type better. To achieve an ideal fit for combination skin, a moisturizing treatment needs ingredients like ceramides, niacinamide, or peptides alongside effective hydrators and skin-repairing extracts to keep moisture balanced and skin radiant without irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [International Journal of Cosmetic Science, 2019](https://pubmed.ncbi.nlm.nih.gov/31050807/)

### Which ingredients make this serum a good fit for combination skin?

Hyaluronic acid and glycerin make this serum a good fit for combination skin by providing hydration without adding oily shine. This product of this type needs effective hydrating and skin-repairing ingredients, such as ceramides, peptides, or niacinamide, to balance moisture and manage oil without irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for combination skin?

Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in the evening routine after cleansing and before moisturizing, though some serums can also be used in the morning or twice a day. Combination skin works best with hydrating ingredients like hyaluronic acid and glycerin alongside soothing plant extracts that provide moisture without adding oily shine.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to give your combination skin hydration without extra shine, followed by your retinol. This combination is generally safe and unlikely to cause irritation.

### How often should I use this serum?

You can use this serum in your evening routine, as treatments fit best there for simplicity and extra safety around sun exposure. If your skin tolerates it well and you want to use it more often, you may also use it in the morning or twice a day.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on your combination skin because it avoids heavy ingredients, though you might notice a slightly sticky finish. Combination skin generally needs lightweight hydrators like hyaluronic acid and glycerin along with soothing plant extracts to keep the face smooth and balanced without feeling greasy.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

You can safely use this serum around the eyes and on the body because its gentle formula is well tolerated by sensitive areas. Hyaluronic acid and glycerin help hydrate delicate skin without causing irritation.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene, geraniol, hexyl cinnamal, and linalool).

## Alternatives for combination skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/it/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/combination-skin) — High fit — €21.00 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/it/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/combination-skin) — High fit — €29.69 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/it/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/combination-skin) — High fit — €17.99 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €13.50 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — €103.91 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — €40.49 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethoxydiglycol, Glycerin, Pyrus Malus Fruit Extract, Peg-12 Dimethicone, Hyaluronic Acid, Chondrus Crispus Extract, Camellia Sinensis Leaf Extract, Aloe Barbadensis Leaf Juice, Sodium Carboxymethyl Beta-Glucan, Epilobium Angustifolium Stem Extract Flower Leaf, Tocopheryl Acetate, Xanthan Gum, Phenoxyethanol, Maltodextrin, Tetrasodium Glutamate Diacetate, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Citric Acid, Limonene, Geraniol, Hexyl Cinnamal, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/advanced-clinicals/hyaluronic-serum/for/combination-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/advanced-clinicals/hyaluronic-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/advanced-clinicals/hyaluronic-serum/for/combination-skin