# Silk amino acids and hexapeptide-9 Page: https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-hexapeptide-9 The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy. Work well together Use them together by applying the [silk amino acids](https://lovi.care/skincare/it/ingredients/silk-amino-acids) first and the [hexapeptide-9](https://lovi.care/skincare/it/ingredients/hexapeptide-9) right after, because they help each other boost skin firmness and moisture. The silk amino acids give your skin the building blocks it needs while the hexapeptide-9 supports firming proteins for a smoother, well-hydrated look. You can keep using them both together, but if your skin feels sensitive, just apply them on alternate days instead. - [All about silk amino acids](https://lovi.care/skincare/it/ingredients/silk-amino-acids) - [All about hexapeptide-9](https://lovi.care/skincare/it/ingredients/hexapeptide-9) ### [Silk amino acids](https://lovi.care/skincare/it/ingredients/silk-amino-acids) products - [Dermalogica Active Moist](https://lovi.care/skincare/it/p/dermalogica/active-moist/for/oily-skin) — High fit — [€55.00 at Amazon](https://www.amazon.it/dp/B000PKYC68?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1) - [Allies of Skin Molecular Silk Amino Hydrating Cleanser](https://lovi.care/skincare/it/p/allies-of-skin/molecular-silk-amino-hydrating-cleanser/for/sensitive-skin) — High fit — [€38.33 at Amazon](https://www.amazon.it/dp/B0BXB76WMB?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1) ### [Hexapeptide-9](https://lovi.care/skincare/it/ingredients/hexapeptide-9) products - [Elemis Pro-Collagen Night Cream](https://lovi.care/skincare/it/p/elemis/pro-collagen-night-cream/for/dry-sensitive-skin) — Superior fit — [€82.90 at Notino](https://www.notino.it/elemis/pro-collagen-oxygenating-night-cream-crema-notte-rassodante-antirughe/p-16125564/) - [Murad Cellular Hydration Repair Serum](https://lovi.care/skincare/it/p/murad/cellular-hydration-repair-serum/for/acne-prone-skin) — High fit - [MARY & MAY 6 Peptide Complex Serum](https://lovi.care/skincare/it/p/mary-and-may/6-peptide-complex-serum/for/mature-skin) — High fit — [€13.08 at Amazon](https://www.amazon.it/dp/B095YHYF33?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1) ## Questions and answers ### Can you use silk amino acids and hexapeptide-9 together? Yes, you can use [silk amino acids](https://lovi.care/skincare/it/ingredients/silk-amino-acids) and [hexapeptide-9](https://lovi.care/skincare/it/ingredients/hexapeptide-9) together because they support structural protein synthesis and moisture balance. This pairing helps improve hydration and repair, making it beneficial for all skin types. [Archives of Dermatological Research, 2016](https://pubmed.ncbi.nlm.nih.gov/26796543/) [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40586182/) ### Which goes first, silk amino acids or hexapeptide-9? Silk amino acids and hexapeptide-9 work well together, and either can be applied first since both support moisture balance and structural proteins. You can easily layer them in your routine to help improve hydration and target skin aging. [Archives of Dermatological Research, 2016](https://pubmed.ncbi.nlm.nih.gov/26796543/) [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40586182/) ### Are silk amino acids and hexapeptide-9 good for sensitive skin? Silk amino acids and hexapeptide-9 work well together to support structural protein synthesis and moisture balance for all skin types. They help hydrate and repair the skin. [Archives of Dermatological Research, 2016](https://pubmed.ncbi.nlm.nih.gov/26796543/) [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40586182/) ## Research on silk amino acids and hexapeptide-9 - [The safety and efficacy of bacterial nanocellulose wound dressing incorporating sericin and polyhexamethylene biguanide: in vitro, in vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/26796543/) Silk amino acids · Archives of Dermatological Research, 2016 - [Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/40586182/) Hexapeptide-9 · Journal of Cosmetic Dermatology, 2025 ## Other combinations - Keep them apart: [Adapalene and hexapeptide-9](https://lovi.care/skincare/it/ingredients/adapalene-and-hexapeptide-9) - Keep them apart: [Granactive retinoid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/granactive-retinoid-and-hexapeptide-9) - Keep them apart: [Hydroxypinacolone retinoate and hexapeptide-9](https://lovi.care/skincare/it/ingredients/hydroxypinacolone-retinoate-and-hexapeptide-9) - Keep them apart: [Pro-retinol and hexapeptide-9](https://lovi.care/skincare/it/ingredients/pro-retinol-and-hexapeptide-9) - Keep them apart: [Retinal and hexapeptide-9](https://lovi.care/skincare/it/ingredients/retinal-and-hexapeptide-9) - Keep them apart: [Retinoid blend and hexapeptide-9](https://lovi.care/skincare/it/ingredients/retinoid-blend-and-hexapeptide-9) - Depends on the strength: [Retinol and hexapeptide-9](https://lovi.care/skincare/it/ingredients/retinol-and-hexapeptide-9) - Keep them apart: [Tretinoin and hexapeptide-9](https://lovi.care/skincare/it/ingredients/tretinoin-and-hexapeptide-9) - Keep them apart: [Vitamin A and hexapeptide-9](https://lovi.care/skincare/it/ingredients/vitamin-a-and-hexapeptide-9) - Work well together: [Liposome and hexapeptide-9](https://lovi.care/skincare/it/ingredients/liposome-and-hexapeptide-9) - Work well together: [Microcapsule and hexapeptide-9](https://lovi.care/skincare/it/ingredients/microcapsule-and-hexapeptide-9) - Depends on the strength: [Vitamin C and hexapeptide-9](https://lovi.care/skincare/it/ingredients/vitamin-c-and-hexapeptide-9) - Work well together: [Betaine and hexapeptide-9](https://lovi.care/skincare/it/ingredients/betaine-and-hexapeptide-9) - Work well together: [Glycerin and hexapeptide-9](https://lovi.care/skincare/it/ingredients/glycerin-and-hexapeptide-9) - Work well together: [Hyaluronic acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-hexapeptide-9) - Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/it/ingredients/niacinamide-and-hexapeptide-9) - Work well together: [Panthenol and hexapeptide-9](https://lovi.care/skincare/it/ingredients/panthenol-and-hexapeptide-9) - Work well together: [Bakuchiol and hexapeptide-9](https://lovi.care/skincare/it/ingredients/bakuchiol-and-hexapeptide-9) - Work well together: [Silk amino acids and acetyl hexapeptide-3](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-acetyl-hexapeptide-3) - Work well together: [Bio-placenta peptides and silk amino acids](https://lovi.care/skincare/it/ingredients/bio-placenta-peptides-and-silk-amino-acids) - Work well together: [Silk amino acids and collagen peptide](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-collagen-peptide) - Work well together: [Silk amino acids and copper peptide](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-copper-peptide) - Work well together: [Hexapeptide and silk amino acids](https://lovi.care/skincare/it/ingredients/hexapeptide-and-silk-amino-acids) - Work well together: [Arginine and hexapeptide-9](https://lovi.care/skincare/it/ingredients/arginine-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and GABA](https://lovi.care/skincare/it/ingredients/hexapeptide-9-and-gaba) - Work well together: [Taurine and hexapeptide-9](https://lovi.care/skincare/it/ingredients/taurine-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and theanine](https://lovi.care/skincare/it/ingredients/hexapeptide-9-and-theanine) - Work well together: [Silk amino acids and palmitoyl pentapeptide-4](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-palmitoyl-pentapeptide-4) - Work well together: [Silk amino acids and palmitoyl tripeptide-1](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-palmitoyl-tripeptide-1) - Work well together: [Silk amino acids and peptide-rich plasma](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-peptide-rich-plasma) - Work well together: [Silk amino acids and triple peptide blend](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-triple-peptide-blend) - Keep them apart: [AHA blend glycolic and citric acids and hexapeptide-9](https://lovi.care/skincare/it/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide-9) - Keep them apart: [Citric acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/citric-acid-and-hexapeptide-9) - Keep them apart: [Glycolic acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/glycolic-acid-and-hexapeptide-9) - Keep them apart: [Lactic acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/lactic-acid-and-hexapeptide-9) - Keep them apart: [Mandelic acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/mandelic-acid-and-hexapeptide-9) - Work well together: [Coenzyme Q10 and hexapeptide-9](https://lovi.care/skincare/it/ingredients/coenzyme-q10-and-hexapeptide-9) - Work well together: [Green tea and hexapeptide-9](https://lovi.care/skincare/it/ingredients/green-tea-and-hexapeptide-9) - Work well together: [Vitamin E and hexapeptide-9](https://lovi.care/skincare/it/ingredients/vitamin-e-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and beta-sitosterol](https://lovi.care/skincare/it/ingredients/hexapeptide-9-and-beta-sitosterol) - Work well together: [Ceramide-building complex and hexapeptide-9](https://lovi.care/skincare/it/ingredients/ceramide-building-complex-and-hexapeptide-9) - Work well together: [Cholesterol and hexapeptide-9](https://lovi.care/skincare/it/ingredients/cholesterol-and-hexapeptide-9) - Work well together: [Phytosphingosine and hexapeptide-9](https://lovi.care/skincare/it/ingredients/phytosphingosine-and-hexapeptide-9) - Work well together: [Phytosterol and hexapeptide-9](https://lovi.care/skincare/it/ingredients/phytosterol-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and squalene](https://lovi.care/skincare/it/ingredients/hexapeptide-9-and-squalene) - Work well together: [Hexapeptide-9 and tri-ceramide complex](https://lovi.care/skincare/it/ingredients/hexapeptide-9-and-tri-ceramide-complex) - Keep them apart: [Salicylic acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/salicylic-acid-and-hexapeptide-9) - Work well together: [AHA blend glycolic and citric acids and silk amino acids](https://lovi.care/skincare/it/ingredients/aha-blend-glycolic-and-citric-acids-and-silk-amino-acids) - Work well together: [Silk amino acids and citric acid](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-citric-acid) - Work well together: [Glycolic acid and silk amino acids](https://lovi.care/skincare/it/ingredients/glycolic-acid-and-silk-amino-acids) - Work well together: [Silk amino acids and lactic acid](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-lactic-acid) - Work well together: [Silk amino acids and mandelic acid](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-mandelic-acid) - Keep them apart: [Hexapeptide-9 and baking soda](https://lovi.care/skincare/it/ingredients/hexapeptide-9-and-baking-soda) - Keep them apart: [Bleach and hexapeptide-9](https://lovi.care/skincare/it/ingredients/bleach-and-hexapeptide-9) - Keep them apart: [Potassium hydroxide and hexapeptide-9](https://lovi.care/skincare/it/ingredients/potassium-hydroxide-and-hexapeptide-9) - Keep them apart: [Hexapeptide-9 and behenyl alcohol](https://lovi.care/skincare/it/ingredients/hexapeptide-9-and-behenyl-alcohol) - Keep them apart: [Hexapeptide-9 and isopropyl alcohol](https://lovi.care/skincare/it/ingredients/hexapeptide-9-and-isopropyl-alcohol) - Keep them apart: [Polyvinyl alcohol and hexapeptide-9](https://lovi.care/skincare/it/ingredients/polyvinyl-alcohol-and-hexapeptide-9) - Keep them apart: [Copper and hexapeptide-9](https://lovi.care/skincare/it/ingredients/copper-and-hexapeptide-9) - Work well together: [Silk amino acids and hyaluronic acid](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-hyaluronic-acid) - Keep them apart: [Benzoyl peroxide and hexapeptide-9](https://lovi.care/skincare/it/ingredients/benzoyl-peroxide-and-hexapeptide-9) - Keep them apart: [Magnesium and hexapeptide-9](https://lovi.care/skincare/it/ingredients/magnesium-and-hexapeptide-9) - Keep them apart: [Zinc and hexapeptide-9](https://lovi.care/skincare/it/ingredients/zinc-and-hexapeptide-9) - Keep them apart: [Zinc sulfate and hexapeptide-9](https://lovi.care/skincare/it/ingredients/zinc-sulfate-and-hexapeptide-9) - Keep them apart: [Azelaic acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-hexapeptide-9) - Keep them apart: [Hexapeptide-9 and protease](https://lovi.care/skincare/it/ingredients/hexapeptide-9-and-protease) - Keep them apart: [Superoxide dismutase and hexapeptide-9](https://lovi.care/skincare/it/ingredients/superoxide-dismutase-and-hexapeptide-9) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/silk-amino-acids-and-hexapeptide-9 - United Kingdom: https://lovi.care/skincare/uk/ingredients/silk-amino-acids-and-hexapeptide-9 - Ireland: https://lovi.care/skincare/ie/ingredients/silk-amino-acids-and-hexapeptide-9 - Germany: https://lovi.care/skincare/de/ingredients/silk-amino-acids-and-hexapeptide-9 - France: https://lovi.care/skincare/fr/ingredients/silk-amino-acids-and-hexapeptide-9 - Italy: https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-hexapeptide-9 (this page) - Netherlands: https://lovi.care/skincare/nl/ingredients/silk-amino-acids-and-hexapeptide-9 - Spain: https://lovi.care/skincare/es/ingredients/silk-amino-acids-and-hexapeptide-9 - Canada: https://lovi.care/skincare/ca/ingredients/silk-amino-acids-and-hexapeptide-9 - Australia: https://lovi.care/skincare/au/ingredients/silk-amino-acids-and-hexapeptide-9 - Singapore: https://lovi.care/skincare/sg/ingredients/silk-amino-acids-and-hexapeptide-9 - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/silk-amino-acids-and-hexapeptide-9 - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/silk-amino-acids-and-hexapeptide-9