# Panthenol and lactic acid

Page: https://lovi.care/skincare/it/ingredients/panthenol-and-lactic-acid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Work well together

Use [lactic acid](https://lovi.care/skincare/it/ingredients/lactic-acid) first, then [panthenol](https://lovi.care/skincare/it/ingredients/panthenol), because panthenol soothes the skin and calms redness caused by the acid. Lactic acid smooths and exfoliates the skin, while panthenol adds moisture and stops irritation. You can use them together, but try a lower acid strength if your skin feels sensitive.

- [All about panthenol](https://lovi.care/skincare/it/ingredients/panthenol)
- [All about lactic acid](https://lovi.care/skincare/it/ingredients/lactic-acid)

### [Panthenol](https://lovi.care/skincare/it/ingredients/panthenol) products

- [Cetaphil Gentle Skin Cleanser](https://lovi.care/skincare/it/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [€12.34 at Amazon](https://www.amazon.it/dp/B0CDXXGBK4?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/it/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [€17.59 at Amazon](https://www.amazon.it/dp/B01N7T7JKJ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/dry-skin) — Superior fit — [€12.09 at Amazon](https://www.amazon.it/dp/B00PBX3L7K?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [CeraVe Healing Ointment](https://lovi.care/skincare/it/p/cerave/healing-ointment/for/dry-skin) — High fit
- [La Roche-Posay Cicaplast Baume B5+](https://lovi.care/skincare/it/p/la-roche-posay/cicaplast-baume-b5/for/sensitive-skin) — Superior fit — [€10.39 at Amazon](https://www.amazon.it/dp/B00ST2GSRK?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Mederma Advanced Scar Gel](https://lovi.care/skincare/it/p/mederma/advanced-scar-gel/for/sensitive-skin) — High fit
- [The Ordinary Hyaluronic Acid 2% + B5](https://lovi.care/skincare/it/p/the-ordinary/hyaluronic-acid-2-b5/for/acne-prone-skin) — High fit — [€9.80 at Amazon](https://www.amazon.it/dp/B01MYEZPC8?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [NIVEA Creme](https://lovi.care/skincare/it/p/nivea/creme/for/dry-skin) — High fit — [€5.28 at Amazon](https://www.amazon.it/dp/B00DT3QNKQ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Aquaphor Lip Repair](https://lovi.care/skincare/it/p/aquaphor/lip-repair/for/dry-skin) — Superior fit
- [Torriden Dive In Serum](https://lovi.care/skincare/it/p/torriden/dive-in-serum/for/acne-prone-skin) — Superior fit — [€31.37 at Amazon](https://www.amazon.it/dp/B07WZ2YTDP?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [RoC Retinol Correxion Line Smoothing Eye Cream](https://lovi.care/skincare/it/p/roc/retinol-correxion-line-smoothing-eye-cream/for/mature-skin) — High fit — [€20.99 at Amazon](https://www.amazon.it/dp/B08GGD7NRN?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Daily Facial Cleanser](https://lovi.care/skincare/it/p/cetaphil/daily-facial-cleanser/for/oily-skin) — Superior fit — [€12.34 at Amazon](https://www.amazon.it/dp/B0CDXXGBK4?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

### [Lactic acid](https://lovi.care/skincare/it/ingredients/lactic-acid) products

- [Medicube Zero Pore Pad](https://lovi.care/skincare/it/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [€17.15 at Amazon](https://www.amazon.it/dp/B09V7Z4TJG?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [First Aid Beauty KP Bump Eraser Body Scrub](https://lovi.care/skincare/it/p/first-aid-beauty/kp-bump-eraser-body-scrub/for/dark-spots) — Average fit — [€29.60 at Amazon](https://www.amazon.it/dp/B08GNS58PQ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [EltaMD UV Clear Broad-Spectrum SPF 46](https://lovi.care/skincare/it/p/eltamd/uv-clear-broad-spectrum-spf-46/for/oily-acne-prone-skin) — Superior fit — [€73.90 at Amazon](https://www.amazon.it/dp/B00ZPWR0N8?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [First Aid Beauty Facial Radiance Pads](https://lovi.care/skincare/it/p/first-aid-beauty/facial-radiance-pads/for/sensitive-skin) — Superior fit — [€17.25 at Lookfantastic](https://www.lookfantastic.it/p/first-aid-beauty-brighten-glow-pads-28-ct./17716506/)
- [CeraVe SA Lotion for Rough & Bumpy Skin](https://lovi.care/skincare/it/p/cerave/sa-lotion-for-rough-and-bumpy-skin/for/oily-skin) — Average fit — [€13.29 at Amazon](https://www.amazon.it/dp/B07WL7WV52?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [CeraVe Renewing SA Cream](https://lovi.care/skincare/it/p/cerave/renewing-sa-cream/for/oily-acne-prone-skin) — High fit
- [The Ordinary Alpha Arbutin 2% + HA](https://lovi.care/skincare/it/p/the-ordinary/alpha-arbutin-2-ha/for/dark-spots) — Superior fit — [€12.08 at Amazon](https://www.amazon.it/dp/B06XCZFCFZ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Retinal 0.2% Emulsion](https://lovi.care/skincare/it/p/the-ordinary/retinal-0-2-emulsion/for/oily-acne-prone-skin) — High fit — [€17.48 at Amazon](https://www.amazon.it/dp/B0CZ5VG3L1?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Kate Somerville ExfoliKate Intensive Exfoliating Treatment](https://lovi.care/skincare/it/p/kate-somerville/exfolikate-intensive-exfoliating-treatment/for/mature-skin) — Superior fit — [€56.90 at Amazon](https://www.amazon.it/dp/B0753531MB?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Dr. Dennis Gross Alpha Beta Universal Daily Peel](https://lovi.care/skincare/it/p/dr-dennis-gross/alpha-beta-universal-daily-peel/for/acne-prone-skin) — Superior fit — [€122.45 at Amazon](https://www.amazon.it/dp/B009QZ595Q?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Lactic Acid 5% + HA](https://lovi.care/skincare/it/p/the-ordinary/lactic-acid-5-ha/for/dry-skin) — Superior fit
- [Good Molecules Overnight Exfoliating Treatment](https://lovi.care/skincare/it/p/good-molecules/overnight-exfoliating-treatment/for/oily-skin) — Superior fit — [€22.99 at Amazon](https://www.amazon.it/dp/B08TMDRF1L?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use panthenol and lactic acid together?

[Panthenol](https://lovi.care/skincare/it/ingredients/panthenol) and [lactic acid](https://lovi.care/skincare/it/ingredients/lactic-acid) work well together because panthenol helps support barrier recovery and may reduce irritation risks from lactic acid. You can find both ingredients in products like Eucerin Anti-Pigment Body Cream and Geek & Gorgeous Liquid Hydration.

[American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/) [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which goes first, panthenol or lactic acid?

Panthenol and lactic acid work well together, with panthenol helping to reduce irritation and support barrier recovery when paired with lactic acid. You can find both ingredients in products like Eucerin Anti-Pigment Body Cream and Geek & Gorgeous Liquid Hydration.

[American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/) [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Are panthenol and lactic acid good for sensitive skin?

Panthenol and lactic acid work well together to support barrier recovery and help reduce the irritation risk from acids. Products like Eucerin Anti-Pigment Body Cream and Geek & Gorgeous Liquid Hydration combine these ingredients.

[American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/) [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

## Research on panthenol and lactic acid

- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Lactate triggers KAT8-mediated LTBP1 lactylation at lysine 752 to promote skin rejuvenation by inducing collagen synthesis in fibroblasts](https://pubmed.ncbi.nlm.nih.gov/39102921/) Lactic acid · International Journal of Biological Macromolecules, 2024
- [Poly-L-Lactic acid increases collagen gene expression and synthesis in cultured dermal fibroblast (Hs68) through the TGF-β/Smad pathway](https://pubmed.ncbi.nlm.nih.gov/36575891/) Lactic acid · Journal of Cosmetic Dermatology, 2023
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Do urea/ammonium lactate combinations achieve better skin protection and hydration than either component alone?](https://pubmed.ncbi.nlm.nih.gov/11803256/) Lactic acid · Skin Pharmacology and Applied Skin Physiology, 2002
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025

## Other combinations

- Work well together: [Panthenol and salicylic acid](https://lovi.care/skincare/it/ingredients/panthenol-and-salicylic-acid)
- Keep them apart: [Benzoyl peroxide and lactic acid](https://lovi.care/skincare/it/ingredients/benzoyl-peroxide-and-lactic-acid)
- Keep them apart: [Retinol and lactic acid](https://lovi.care/skincare/it/ingredients/retinol-and-lactic-acid)
- Depends on the strength: [Niacinamide and lactic acid](https://lovi.care/skincare/it/ingredients/niacinamide-and-lactic-acid)
- Work well together: [Lactic acid and sodium lactate](https://lovi.care/skincare/it/ingredients/lactic-acid-and-sodium-lactate)
- Work well together: [Lactic acid and tromethamine](https://lovi.care/skincare/it/ingredients/lactic-acid-and-tromethamine)
- Work well together: [Lactic acid and betaine](https://lovi.care/skincare/it/ingredients/lactic-acid-and-betaine)
- Work well together: [Glycerin and lactic acid](https://lovi.care/skincare/it/ingredients/glycerin-and-lactic-acid)
- Depends on the strength: [Lactic acid and hyaluronic acid](https://lovi.care/skincare/it/ingredients/lactic-acid-and-hyaluronic-acid)
- Work well together: [Panthenol and acetyl hexapeptide-3](https://lovi.care/skincare/it/ingredients/panthenol-and-acetyl-hexapeptide-3)
- Work well together: [Panthenol and bio-placenta peptides](https://lovi.care/skincare/it/ingredients/panthenol-and-bio-placenta-peptides)
- Work well together: [Panthenol and collagen peptide](https://lovi.care/skincare/it/ingredients/panthenol-and-collagen-peptide)
- Work well together: [Panthenol and copper peptide](https://lovi.care/skincare/it/ingredients/panthenol-and-copper-peptide)
- Work well together: [Panthenol and hexapeptide](https://lovi.care/skincare/it/ingredients/panthenol-and-hexapeptide)
- Work well together: [Panthenol and hexapeptide-9](https://lovi.care/skincare/it/ingredients/panthenol-and-hexapeptide-9)
- Work well together: [Panthenol and palmitoyl pentapeptide-4](https://lovi.care/skincare/it/ingredients/panthenol-and-palmitoyl-pentapeptide-4)
- Work well together: [Panthenol and palmitoyl tripeptide-1](https://lovi.care/skincare/it/ingredients/panthenol-and-palmitoyl-tripeptide-1)
- Work well together: [Panthenol and peptide-rich plasma](https://lovi.care/skincare/it/ingredients/panthenol-and-peptide-rich-plasma)
- Work well together: [Panthenol and triple peptide blend](https://lovi.care/skincare/it/ingredients/panthenol-and-triple-peptide-blend)
- Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/it/ingredients/lactic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Bio-placenta peptides and lactic acid](https://lovi.care/skincare/it/ingredients/bio-placenta-peptides-and-lactic-acid)
- Keep them apart: [Carnosine and lactic acid](https://lovi.care/skincare/it/ingredients/carnosine-and-lactic-acid)
- Keep them apart: [Lactic acid and collagen peptide](https://lovi.care/skincare/it/ingredients/lactic-acid-and-collagen-peptide)
- Keep them apart: [Lactic acid and copper peptide](https://lovi.care/skincare/it/ingredients/lactic-acid-and-copper-peptide)
- Keep them apart: [Hexapeptide and lactic acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-lactic-acid)
- Keep them apart: [Lactic acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/lactic-acid-and-hexapeptide-9)
- Keep them apart: [Lactic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/it/ingredients/lactic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Lactic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/it/ingredients/lactic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Lactic acid and peptide-rich plasma](https://lovi.care/skincare/it/ingredients/lactic-acid-and-peptide-rich-plasma)
- Keep them apart: [Lactic acid and triple peptide blend](https://lovi.care/skincare/it/ingredients/lactic-acid-and-triple-peptide-blend)
- Keep them apart: [Adapalene and lactic acid](https://lovi.care/skincare/it/ingredients/adapalene-and-lactic-acid)
- Keep them apart: [Lactic acid and granactive retinoid](https://lovi.care/skincare/it/ingredients/lactic-acid-and-granactive-retinoid)
- Keep them apart: [Lactic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/it/ingredients/lactic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and lactic acid](https://lovi.care/skincare/it/ingredients/pro-retinol-and-lactic-acid)
- Keep them apart: [Retinal and lactic acid](https://lovi.care/skincare/it/ingredients/retinal-and-lactic-acid)
- Keep them apart: [Lactic acid and retinoid blend](https://lovi.care/skincare/it/ingredients/lactic-acid-and-retinoid-blend)
- Keep them apart: [Tretinoin and lactic acid](https://lovi.care/skincare/it/ingredients/tretinoin-and-lactic-acid)
- Work well together: [Lactic acid and gluconolactone](https://lovi.care/skincare/it/ingredients/lactic-acid-and-gluconolactone)
- Work well together: [Lactic acid and lactobionic acid](https://lovi.care/skincare/it/ingredients/lactic-acid-and-lactobionic-acid)
- Work well together: [Lactic acid and cholesterol](https://lovi.care/skincare/it/ingredients/lactic-acid-and-cholesterol)
- Work well together: [Lactic acid and lauric acid](https://lovi.care/skincare/it/ingredients/lactic-acid-and-lauric-acid)
- Work well together: [Linoleic acid and lactic acid](https://lovi.care/skincare/it/ingredients/linoleic-acid-and-lactic-acid)
- Keep them apart: [Lactic acid and tri-ceramide complex](https://lovi.care/skincare/it/ingredients/lactic-acid-and-tri-ceramide-complex)
- Work well together: [Arginine and lactic acid](https://lovi.care/skincare/it/ingredients/arginine-and-lactic-acid)
- Work well together: [Lactic acid and GABA](https://lovi.care/skincare/it/ingredients/lactic-acid-and-gaba)
- Work well together: [Silk amino acids and lactic acid](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-lactic-acid)
- Work well together: [Lactic acid and taurine](https://lovi.care/skincare/it/ingredients/lactic-acid-and-taurine)
- Work well together: [Lactic acid and theanine](https://lovi.care/skincare/it/ingredients/lactic-acid-and-theanine)
- Work well together: [Ferulic acid and lactic acid](https://lovi.care/skincare/it/ingredients/ferulic-acid-and-lactic-acid)
- Work well together: [Vitamin E and lactic acid](https://lovi.care/skincare/it/ingredients/vitamin-e-and-lactic-acid)
- Keep them apart: [Azelaic acid and lactic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-lactic-acid)
- Keep them apart: [Salicylic acid and lactic acid](https://lovi.care/skincare/it/ingredients/salicylic-acid-and-lactic-acid)
- Work well together: [Panthenol and aha blend glycolic and citric acids](https://lovi.care/skincare/it/ingredients/panthenol-and-aha-blend-glycolic-and-citric-acids)
- Work well together: [Panthenol and citric acid](https://lovi.care/skincare/it/ingredients/panthenol-and-citric-acid)
- Work well together: [Glycolic acid and panthenol](https://lovi.care/skincare/it/ingredients/glycolic-acid-and-panthenol)
- Work well together: [Allantoin and lactic acid](https://lovi.care/skincare/it/ingredients/allantoin-and-lactic-acid)
- Work well together: [Lactic acid and bisabolol](https://lovi.care/skincare/it/ingredients/lactic-acid-and-bisabolol)
- Work well together: [Panthenol and mandelic acid](https://lovi.care/skincare/it/ingredients/panthenol-and-mandelic-acid)
- Work well together: [Panthenol and hyaluronic acid](https://lovi.care/skincare/it/ingredients/panthenol-and-hyaluronic-acid)
- Work well together: [Panthenol and tri-ceramide complex](https://lovi.care/skincare/it/ingredients/panthenol-and-tri-ceramide-complex)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/panthenol-and-lactic-acid
- United Kingdom: https://lovi.care/skincare/uk/ingredients/panthenol-and-lactic-acid
- Ireland: https://lovi.care/skincare/ie/ingredients/panthenol-and-lactic-acid
- Germany: https://lovi.care/skincare/de/ingredients/panthenol-and-lactic-acid
- France: https://lovi.care/skincare/fr/ingredients/panthenol-and-lactic-acid
- Italy: https://lovi.care/skincare/it/ingredients/panthenol-and-lactic-acid (this page)
- Netherlands: https://lovi.care/skincare/nl/ingredients/panthenol-and-lactic-acid
- Spain: https://lovi.care/skincare/es/ingredients/panthenol-and-lactic-acid
- Canada: https://lovi.care/skincare/ca/ingredients/panthenol-and-lactic-acid
- Australia: https://lovi.care/skincare/au/ingredients/panthenol-and-lactic-acid
- Singapore: https://lovi.care/skincare/sg/ingredients/panthenol-and-lactic-acid
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/panthenol-and-lactic-acid
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/panthenol-and-lactic-acid
