# Hexapeptide Page: https://lovi.care/skincare/it/ingredients/hexapeptide The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy. Hexapeptide visibly softens wrinkles, smooths skin roughness, eases post-treatment tenderness, and boosts skin hydration. It suits most skin types best and is commonly found in nourishing [serums](https://lovi.care/skincare/it/ingredients/serum). It fits smoothly into a routine alongside [panthenol](https://lovi.care/skincare/it/ingredients/panthenol), [green tea](https://lovi.care/skincare/it/ingredients/green-tea), and ceramide-building complexes, while remaining separate from [adapalene](https://lovi.care/skincare/it/ingredients/adapalene), [glycolic acid](https://lovi.care/skincare/it/ingredients/glycolic-acid), and [benzoyl peroxide](https://lovi.care/skincare/it/ingredients/benzoyl-peroxide). [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/) [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28371204/) [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/) This page shows hexapeptide products with a Lovi page. For every product, and a routine built for your skin, use the Lovi app. ### Popular hexapeptide products - [SkinCeuticals P-TOX](https://lovi.care/skincare/it/p/skinceuticals/p-tox/for/mature-skin) — High fit — [€155.25 at Lookfantastic](https://www.lookfantastic.it/p/skinceuticals-p-tiox-neuro-peptide-serum-30ml/15456548/) ## What to combine hexapeptide with Ingredient Together How to use them [Panthenol](https://lovi.care/skincare/it/ingredients/panthenol) Works well Use them together in the same routine, applying [panthenol](https://lovi.care/skincare/it/ingredients/panthenol) first to calm the skin and hexapeptide second to firm it. [Hexapeptide and panthenol](https://lovi.care/skincare/it/ingredients/panthenol-and-hexapeptide) [Green tea](https://lovi.care/skincare/it/ingredients/green-tea) Works well Use [green tea](https://lovi.care/skincare/it/ingredients/green-tea) and hexapeptide together in the same routine, applying green tea first and hexapeptide right after, because they help each other work better. [Hexapeptide and green tea](https://lovi.care/skincare/it/ingredients/green-tea-and-hexapeptide) [Ceramide-building complex](https://lovi.care/skincare/it/ingredients/ceramide-building-complex) Works well Use them together in the same routine, applying the ceramide [complex](https://lovi.care/skincare/it/ingredients/complex) first and the hexapeptide right after, because the lipids help your skin absorb the peptide better. [Hexapeptide and ceramide-building complex](https://lovi.care/skincare/it/ingredients/ceramide-building-complex-and-hexapeptide) [Glycerin](https://lovi.care/skincare/it/ingredients/glycerin) Works well Use them together by applying your [glycerin](https://lovi.care/skincare/it/ingredients/glycerin) hydrating [serum](https://lovi.care/skincare/it/ingredients/serum) first, followed by your hexapeptide product, because hydration helps the peptides absorb better. [Hexapeptide and glycerin](https://lovi.care/skincare/it/ingredients/glycerin-and-hexapeptide) [Coenzyme Q10](https://lovi.care/skincare/it/ingredients/coenzyme-q10) Works well Use them together by applying [coenzyme Q10](https://lovi.care/skincare/it/ingredients/coenzyme-q10) first and hexapeptide second, because they work well as a team. [Hexapeptide and coenzyme q10](https://lovi.care/skincare/it/ingredients/coenzyme-q10-and-hexapeptide) [Vitamin E](https://lovi.care/skincare/it/ingredients/vitamin-e) Works well Use them together in the same routine, applying the [vitamin E](https://lovi.care/skincare/it/ingredients/vitamin-e) product first and the hexapeptide product second, because they help each other work better. [Hexapeptide and vitamin E](https://lovi.care/skincare/it/ingredients/vitamin-e-and-hexapeptide) [Bakuchiol](https://lovi.care/skincare/it/ingredients/bakuchiol) Works well Use them together in the same routine, applying your [bakuchiol](https://lovi.care/skincare/it/ingredients/bakuchiol) product first and then your hexapeptide cream. [Hexapeptide and bakuchiol](https://lovi.care/skincare/it/ingredients/bakuchiol-and-hexapeptide) [Silk amino acids](https://lovi.care/skincare/it/ingredients/silk-amino-acids) Works well Use them together in the same routine, applying the [silk amino acids](https://lovi.care/skincare/it/ingredients/silk-amino-acids) first and the hexapeptide right after, because they boost each other. [Hexapeptide and silk amino acids](https://lovi.care/skincare/it/ingredients/hexapeptide-and-silk-amino-acids) [Arginine](https://lovi.care/skincare/it/ingredients/arginine) Works well Use them together, applying the peptide first and the amino acid right after, because they help each other repair the skin barrier. [Hexapeptide and arginine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-arginine) [Liposome](https://lovi.care/skincare/it/ingredients/liposome) Works well Use them together in the same routine, applying the [liposome](https://lovi.care/skincare/it/ingredients/liposome) product first and the hexapeptide product right after. [Hexapeptide and liposome](https://lovi.care/skincare/it/ingredients/hexapeptide-and-liposome) [Taurine](https://lovi.care/skincare/it/ingredients/taurine) Works well Use them together in the same routine, because they support healthy skin and moisture balance. [Hexapeptide and taurine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-taurine) [Hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) Works well Apply the [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) first to hydrate the skin, and then follow with the hexapeptide. [Hexapeptide and hyaluronic acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-hyaluronic-acid) [Microcapsule](https://lovi.care/skincare/it/ingredients/microcapsule) Works well Use them together in the same routine, applying the [microcapsules](https://lovi.care/skincare/it/ingredients/microcapsule) before the hexapeptide to help it absorb better. [Hexapeptide and microcapsule](https://lovi.care/skincare/it/ingredients/hexapeptide-and-microcapsule) [Cholesterol](https://lovi.care/skincare/it/ingredients/cholesterol) Works well Use them together in the same routine, applying the peptide product first and the [cholesterol](https://lovi.care/skincare/it/ingredients/cholesterol) cream right after, because lipids help peptides soak in better. [Hexapeptide and cholesterol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-cholesterol) [Phytosphingosine](https://lovi.care/skincare/it/ingredients/phytosphingosine) Works well Use them together by applying the hexapeptide first and the [phytosphingosine](https://lovi.care/skincare/it/ingredients/phytosphingosine) right after, because lipids help the peptide absorb better. [Hexapeptide and phytosphingosine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-phytosphingosine) [Betaine](https://lovi.care/skincare/it/ingredients/betaine) Works well Use them together by applying the [betaine](https://lovi.care/skincare/it/ingredients/betaine) hydrating serum first, followed by the hexapeptide, because moisture helps peptides work better. [Hexapeptide and betaine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-betaine) [Phytosterol](https://lovi.care/skincare/it/ingredients/phytosterol) Works well Use them together in the same routine, applying the peptide serum first and following it with the [phytosterol](https://lovi.care/skincare/it/ingredients/phytosterol) cream. [Hexapeptide and phytosterol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-phytosterol) [Beta-sitosterol](https://lovi.care/skincare/it/ingredients/beta-sitosterol) Works well Use them together in the same routine, applying the hexapeptide first and the [beta-sitosterol](https://lovi.care/skincare/it/ingredients/beta-sitosterol) right after to lock it in. [Hexapeptide and beta-sitosterol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-beta-sitosterol) [Squalene](https://lovi.care/skincare/it/ingredients/squalene) Works well Use them together by applying the peptide serum first, because the [squalene oil](https://lovi.care/skincare/it/ingredients/squalene) helps it sink in and locks in moisture. [Hexapeptide and squalene](https://lovi.care/skincare/it/ingredients/hexapeptide-and-squalene) [Tri-ceramide complex](https://lovi.care/skincare/it/ingredients/tri-ceramide-complex) Works well Use them together in the same routine, applying the [tri-ceramide complex](https://lovi.care/skincare/it/ingredients/tri-ceramide-complex) first and the hexapeptide right after, because the lipids help the peptides absorb better. [Hexapeptide and tri-ceramide complex](https://lovi.care/skincare/it/ingredients/hexapeptide-and-tri-ceramide-complex) [GABA](https://lovi.care/skincare/it/ingredients/gaba) Works well Use them together in the same routine, because they team up to hydrate and repair your skin. [Hexapeptide and GABA](https://lovi.care/skincare/it/ingredients/hexapeptide-and-gaba) [Theanine](https://lovi.care/skincare/it/ingredients/theanine) Works well Use them together in the same routine, because they help each other keep your skin hydrated and firm. [Hexapeptide and theanine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-theanine) [Vitamin C](https://lovi.care/skincare/it/ingredients/vitamin-c) Depends Apply [vitamin C](https://lovi.care/skincare/it/ingredients/vitamin-c) in the morning and hexapeptide at night because mixing them reduces their effectiveness. [Hexapeptide and vitamin C](https://lovi.care/skincare/it/ingredients/vitamin-c-and-hexapeptide) [Retinol](https://lovi.care/skincare/it/ingredients/retinol) Depends Use them at different times of day with peptides in the morning and [retinol](https://lovi.care/skincare/it/ingredients/retinol) at night, because combining them all at once can irritate skin. [Hexapeptide and retinol](https://lovi.care/skincare/it/ingredients/retinol-and-hexapeptide) [Niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide) Depends Use them together in the same routine, because [niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide) helps strengthen the skin while the peptide supports anti-aging and firmness. [Hexapeptide and niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide-and-hexapeptide) [Adapalene](https://lovi.care/skincare/it/ingredients/adapalene) Keep apart Use them at different times of day by applying your peptide product in the morning and [adapalene](https://lovi.care/skincare/it/ingredients/adapalene) at night to avoid skin irritation. [Hexapeptide and adapalene](https://lovi.care/skincare/it/ingredients/adapalene-and-hexapeptide) [Glycolic acid](https://lovi.care/skincare/it/ingredients/glycolic-acid) Keep apart Use them at different times of day, applying [glycolic acid](https://lovi.care/skincare/it/ingredients/glycolic-acid) in the morning and hexapeptide at night, because acid ruins peptide strength. [Hexapeptide and glycolic acid](https://lovi.care/skincare/it/ingredients/glycolic-acid-and-hexapeptide) [Benzoyl peroxide](https://lovi.care/skincare/it/ingredients/benzoyl-peroxide) Keep apart Apply them at different times of day, using [benzoyl peroxide](https://lovi.care/skincare/it/ingredients/benzoyl-peroxide) in the morning and hexapeptide at night, because heat and certain harsh conditions can break down the peptide. [Hexapeptide and benzoyl peroxide](https://lovi.care/skincare/it/ingredients/benzoyl-peroxide-and-hexapeptide) [Azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid) Keep apart Use [azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid) and hexapeptide at different times of day, applying the acid in the morning and the peptide at night, because mixing them together makes the peptide lose its power. [Hexapeptide and azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-hexapeptide) [AHA blend glycolic and citric acids](https://lovi.care/skincare/it/ingredients/aha-blend-glycolic-and-citric-acids) Keep apart Use them at different times of day by applying the acid in the morning and the hexapeptide at night, because the acid breaks down the peptide. [Hexapeptide and aha blend glycolic and citric acids](https://lovi.care/skincare/it/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide) [Salicylic acid](https://lovi.care/skincare/it/ingredients/salicylic-acid) Keep apart Use them at different times of day, applying [salicylic acid](https://lovi.care/skincare/it/ingredients/salicylic-acid) first and hexapeptide later, because acid destroys peptide power. [Hexapeptide and salicylic acid](https://lovi.care/skincare/it/ingredients/salicylic-acid-and-hexapeptide) [Tretinoin](https://lovi.care/skincare/it/ingredients/tretinoin) Keep apart Use them at different times of day by applying your peptide product in the morning and [tretinoin](https://lovi.care/skincare/it/ingredients/tretinoin) at night to prevent skin irritation. [Hexapeptide and tretinoin](https://lovi.care/skincare/it/ingredients/tretinoin-and-hexapeptide) [Vitamin A](https://lovi.care/skincare/it/ingredients/vitamin-a) Keep apart Use them at different times of day, applying [vitamin A](https://lovi.care/skincare/it/ingredients/vitamin-a) at night and hexapeptide in the morning, to prevent skin irritation. [Hexapeptide and vitamin A](https://lovi.care/skincare/it/ingredients/hexapeptide-and-vitamin-a) [Pro-retinol](https://lovi.care/skincare/it/ingredients/pro-retinol) Keep apart Use them at different times of day by applying your pro-retinol at night and your hexapeptide in the morning to avoid extra skin irritation. [Hexapeptide and pro-retinol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-pro-retinol) [Retinal](https://lovi.care/skincare/it/ingredients/retinal) Keep apart Use them at different times of day, applying [retinal](https://lovi.care/skincare/it/ingredients/retinal) at night and hexapeptide in the morning, to prevent skin irritation. [Hexapeptide and retinal](https://lovi.care/skincare/it/ingredients/hexapeptide-and-retinal) [Copper](https://lovi.care/skincare/it/ingredients/copper) Keep apart Use them on alternate nights, applying [copper](https://lovi.care/skincare/it/ingredients/copper) first and hexapeptide later, because they can cancel each other out. [Hexapeptide and copper](https://lovi.care/skincare/it/ingredients/hexapeptide-and-copper) [Magnesium](https://lovi.care/skincare/it/ingredients/magnesium) Keep apart Use them at different times of day, applying the peptide serum in the morning and the [magnesium](https://lovi.care/skincare/it/ingredients/magnesium) at night, because they cancel each other out. [Hexapeptide and magnesium](https://lovi.care/skincare/it/ingredients/hexapeptide-and-magnesium) [Lactic acid](https://lovi.care/skincare/it/ingredients/lactic-acid) Keep apart Apply [lactic acid](https://lovi.care/skincare/it/ingredients/lactic-acid) and hexapeptide at different times of day because acids break down peptides and ruin their anti-aging power. [Hexapeptide and lactic acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-lactic-acid) [Mandelic acid](https://lovi.care/skincare/it/ingredients/mandelic-acid) Keep apart Use them at different times of day by applying [mandelic acid](https://lovi.care/skincare/it/ingredients/mandelic-acid) in the morning and hexapeptide at night, because acid breaks down the peptide. [Hexapeptide and mandelic acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-mandelic-acid) [Retinoid blend](https://lovi.care/skincare/it/ingredients/retinoid-blend) Keep apart Use them at different times of day, applying the retinoid at night and the hexapeptide in the morning. [Hexapeptide and retinoid blend](https://lovi.care/skincare/it/ingredients/hexapeptide-and-retinoid-blend) [Superoxide dismutase](https://lovi.care/skincare/it/ingredients/superoxide-dismutase) Keep apart Use them at different times of day, applying hexapeptide in the morning and [superoxide dismutase](https://lovi.care/skincare/it/ingredients/superoxide-dismutase) at night, because their active structures clash. [Hexapeptide and superoxide dismutase](https://lovi.care/skincare/it/ingredients/hexapeptide-and-superoxide-dismutase) [Polyvinyl alcohol](https://lovi.care/skincare/it/ingredients/polyvinyl-alcohol) Keep apart Use them at different times of day, applying the peptide first, because they clash and cancel each other out. [Hexapeptide and polyvinyl alcohol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-polyvinyl-alcohol) [Zinc](https://lovi.care/skincare/it/ingredients/zinc) Keep apart Use them at different times of day, applying the peptide first and the [zinc](https://lovi.care/skincare/it/ingredients/zinc) later, because mixing them makes the peptide less effective. [Hexapeptide and zinc](https://lovi.care/skincare/it/ingredients/hexapeptide-and-zinc) [Zinc sulfate](https://lovi.care/skincare/it/ingredients/zinc-sulfate) Keep apart Use them at different times of day, applying the peptide first and the zinc later, because they cancel each other out when mixed. [Hexapeptide and zinc sulfate](https://lovi.care/skincare/it/ingredients/hexapeptide-and-zinc-sulfate) [Bleach](https://lovi.care/skincare/it/ingredients/bleach) Keep apart Use them at different times of day, applying the peptide first and the [bleach](https://lovi.care/skincare/it/ingredients/bleach) later, because mixing them destroys the peptide benefits. [Hexapeptide and bleach](https://lovi.care/skincare/it/ingredients/hexapeptide-and-bleach) [Granactive retinoid](https://lovi.care/skincare/it/ingredients/granactive-retinoid) Keep apart Use them at different times of day, applying the peptide serum in the morning and the retinoid at night, to avoid extra skin irritation. [Hexapeptide and granactive retinoid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-granactive-retinoid) [Hydroxypinacolone retinoate](https://lovi.care/skincare/it/ingredients/hydroxypinacolone-retinoate) Keep apart Use them at different times of day by applying your peptide product in the morning and your [hydroxypinacolone retinoate](https://lovi.care/skincare/it/ingredients/hydroxypinacolone-retinoate) at night. [Hexapeptide and hydroxypinacolone retinoate](https://lovi.care/skincare/it/ingredients/hexapeptide-and-hydroxypinacolone-retinoate) [Potassium hydroxide](https://lovi.care/skincare/it/ingredients/potassium-hydroxide) Keep apart Use them at different times of day, applying the peptide first and the [potassium hydroxide](https://lovi.care/skincare/it/ingredients/potassium-hydroxide) later, because they clash in chemical balance. [Hexapeptide and potassium hydroxide](https://lovi.care/skincare/it/ingredients/hexapeptide-and-potassium-hydroxide) [Citric acid](https://lovi.care/skincare/it/ingredients/citric-acid) Keep apart Use them at different times of day, applying the acid first and the peptide later, because mixing them makes the peptide lose its power. [Hexapeptide and citric acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-citric-acid) [Isopropyl alcohol](https://lovi.care/skincare/it/ingredients/isopropyl-alcohol) Keep apart Use them at different times of day, applying the hexapeptide first, because alcohol damages the peptide. [Hexapeptide and isopropyl alcohol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-isopropyl-alcohol) [Behenyl alcohol](https://lovi.care/skincare/it/ingredients/behenyl-alcohol) Keep apart Use them at different times of day, applying the peptide first, because alcohol makes the peptide less effective. [Hexapeptide and behenyl alcohol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-behenyl-alcohol) [Protease](https://lovi.care/skincare/it/ingredients/protease) Keep apart Use them at different times of day, applying the peptide product in the morning and the [protease](https://lovi.care/skincare/it/ingredients/protease) at night, because they cancel each other out. [Hexapeptide and protease](https://lovi.care/skincare/it/ingredients/hexapeptide-and-protease) [Baking soda](https://lovi.care/skincare/it/ingredients/baking-soda) Keep apart Use them at different times of day by applying your peptide product first, because [baking soda](https://lovi.care/skincare/it/ingredients/baking-soda) stops peptides from working properly. [Hexapeptide and baking soda](https://lovi.care/skincare/it/ingredients/hexapeptide-and-baking-soda) From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app. ## Questions and answers ### What does hexapeptide do for the skin? Hexapeptide helps decrease skin roughness and improves wrinkles when used consistently. Studies show it can produce significant anti-wrinkle effects and improve skin hydration over several weeks of treatment. [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/) [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/) ### How do you use hexapeptide? You can use hexapeptide twice daily to help reduce wrinkles and smooth the skin. Applying it regularly supports anti-aging benefits and improves overall skin firmness. [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/) ### Should you use hexapeptide in the morning or at night? You can use hexapeptide twice daily as it helps produce an anti-wrinkle effect and decreases skin roughness. [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/) ### Can you use hexapeptide every day? Yes, you can use hexapeptide twice daily for effective anti-wrinkle care and reduced skin roughness. [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/) ### Does hexapeptide cause purging or irritation? Hexapeptide is unlikely to cause purging or irritation when used properly. According to Lovi fit ratings, it is often paired carefully with other ingredients to maintain skin comfort. ### Which skin types is hexapeptide best for? Hexapeptide is suitable for various skin types when used with compatible ingredients like [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) or [panthenol](https://lovi.care/skincare/it/ingredients/panthenol) to help firm and hydrate the skin. [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/) ### Can you use hexapeptide with panthenol? Yes, you can use hexapeptide and panthenol together in the same routine, applying panthenol first to calm the skin and hexapeptide second to firm it. ### Can you use hexapeptide with adapalene? You should keep hexapeptide and [adapalene](https://lovi.care/skincare/it/ingredients/adapalene) apart. Use them at different times of day by applying your peptide product in the morning and adapalene at night to avoid skin irritation. ## Research on hexapeptide - [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Hexapeptide · American Journal of Clinical Dermatology, 2013 - [A randomized, single-blinded trial of a tripeptide/hexapeptide healing regimen following laser resurfacing of the face](https://pubmed.ncbi.nlm.nih.gov/28371204/) Hexapeptide · Journal of Cosmetic Dermatology, 2017 - [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Hexapeptide · Annals of Dermatology, 2019 ## Combining hexapeptide - Keep them apart: [Adapalene and hexapeptide](https://lovi.care/skincare/it/ingredients/adapalene-and-hexapeptide) - Keep them apart: [Hexapeptide and granactive retinoid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-granactive-retinoid) - Keep them apart: [Hexapeptide and hydroxypinacolone retinoate](https://lovi.care/skincare/it/ingredients/hexapeptide-and-hydroxypinacolone-retinoate) - Keep them apart: [Hexapeptide and pro-retinol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-pro-retinol) - Keep them apart: [Hexapeptide and retinal](https://lovi.care/skincare/it/ingredients/hexapeptide-and-retinal) - Keep them apart: [Hexapeptide and retinoid blend](https://lovi.care/skincare/it/ingredients/hexapeptide-and-retinoid-blend) - Depends on the strength: [Retinol and hexapeptide](https://lovi.care/skincare/it/ingredients/retinol-and-hexapeptide) - Keep them apart: [Tretinoin and hexapeptide](https://lovi.care/skincare/it/ingredients/tretinoin-and-hexapeptide) - Keep them apart: [Hexapeptide and vitamin A](https://lovi.care/skincare/it/ingredients/hexapeptide-and-vitamin-a) - Work well together: [Hexapeptide and liposome](https://lovi.care/skincare/it/ingredients/hexapeptide-and-liposome) - Work well together: [Hexapeptide and microcapsule](https://lovi.care/skincare/it/ingredients/hexapeptide-and-microcapsule) - Depends on the strength: [Vitamin C and hexapeptide](https://lovi.care/skincare/it/ingredients/vitamin-c-and-hexapeptide) - Work well together: [Hexapeptide and betaine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-betaine) - Work well together: [Glycerin and hexapeptide](https://lovi.care/skincare/it/ingredients/glycerin-and-hexapeptide) - Work well together: [Hexapeptide and hyaluronic acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-hyaluronic-acid) - Depends on the strength: [Niacinamide and hexapeptide](https://lovi.care/skincare/it/ingredients/niacinamide-and-hexapeptide) - Work well together: [Panthenol and hexapeptide](https://lovi.care/skincare/it/ingredients/panthenol-and-hexapeptide) - Work well together: [Bakuchiol and hexapeptide](https://lovi.care/skincare/it/ingredients/bakuchiol-and-hexapeptide) - Work well together: [Hexapeptide and arginine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-arginine) - Work well together: [Hexapeptide and GABA](https://lovi.care/skincare/it/ingredients/hexapeptide-and-gaba) - Work well together: [Hexapeptide and silk amino acids](https://lovi.care/skincare/it/ingredients/hexapeptide-and-silk-amino-acids) - Work well together: [Hexapeptide and taurine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-taurine) - Work well together: [Hexapeptide and theanine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-theanine) - Keep them apart: [AHA blend glycolic and citric acids and hexapeptide](https://lovi.care/skincare/it/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide) - Keep them apart: [Hexapeptide and citric acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-citric-acid) - Keep them apart: [Glycolic acid and hexapeptide](https://lovi.care/skincare/it/ingredients/glycolic-acid-and-hexapeptide) - Keep them apart: [Hexapeptide and lactic acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-lactic-acid) - Keep them apart: [Hexapeptide and mandelic acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-mandelic-acid) - Work well together: [Coenzyme Q10 and hexapeptide](https://lovi.care/skincare/it/ingredients/coenzyme-q10-and-hexapeptide) - Work well together: [Green tea and hexapeptide](https://lovi.care/skincare/it/ingredients/green-tea-and-hexapeptide) - Work well together: [Vitamin E and hexapeptide](https://lovi.care/skincare/it/ingredients/vitamin-e-and-hexapeptide) - Work well together: [Hexapeptide and beta-sitosterol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-beta-sitosterol) - Work well together: [Ceramide-building complex and hexapeptide](https://lovi.care/skincare/it/ingredients/ceramide-building-complex-and-hexapeptide) - Work well together: [Hexapeptide and cholesterol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-cholesterol) - Work well together: [Hexapeptide and phytosphingosine](https://lovi.care/skincare/it/ingredients/hexapeptide-and-phytosphingosine) - Work well together: [Hexapeptide and phytosterol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-phytosterol) - Work well together: [Hexapeptide and squalene](https://lovi.care/skincare/it/ingredients/hexapeptide-and-squalene) - Work well together: [Hexapeptide and tri-ceramide complex](https://lovi.care/skincare/it/ingredients/hexapeptide-and-tri-ceramide-complex) - Keep them apart: [Salicylic acid and hexapeptide](https://lovi.care/skincare/it/ingredients/salicylic-acid-and-hexapeptide) - Keep them apart: [Hexapeptide and baking soda](https://lovi.care/skincare/it/ingredients/hexapeptide-and-baking-soda) - Keep them apart: [Hexapeptide and bleach](https://lovi.care/skincare/it/ingredients/hexapeptide-and-bleach) - Keep them apart: [Hexapeptide and potassium hydroxide](https://lovi.care/skincare/it/ingredients/hexapeptide-and-potassium-hydroxide) - Keep them apart: [Hexapeptide and behenyl alcohol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-behenyl-alcohol) - Keep them apart: [Hexapeptide and isopropyl alcohol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-isopropyl-alcohol) - Keep them apart: [Hexapeptide and polyvinyl alcohol](https://lovi.care/skincare/it/ingredients/hexapeptide-and-polyvinyl-alcohol) - Keep them apart: [Hexapeptide and copper](https://lovi.care/skincare/it/ingredients/hexapeptide-and-copper) - Keep them apart: [Hexapeptide and magnesium](https://lovi.care/skincare/it/ingredients/hexapeptide-and-magnesium) - Keep them apart: [Hexapeptide and zinc](https://lovi.care/skincare/it/ingredients/hexapeptide-and-zinc) - Keep them apart: [Hexapeptide and zinc sulfate](https://lovi.care/skincare/it/ingredients/hexapeptide-and-zinc-sulfate) - Keep them apart: [Benzoyl peroxide and hexapeptide](https://lovi.care/skincare/it/ingredients/benzoyl-peroxide-and-hexapeptide) - Keep them apart: [Azelaic acid and hexapeptide](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-hexapeptide) - Keep them apart: [Hexapeptide and protease](https://lovi.care/skincare/it/ingredients/hexapeptide-and-protease) - Keep them apart: [Hexapeptide and superoxide dismutase](https://lovi.care/skincare/it/ingredients/hexapeptide-and-superoxide-dismutase) ## Brands with hexapeptide - American skincare: [SkinCeuticals](https://lovi.care/skincare/it/brands/skinceuticals) ## Related ingredients - [Adapalene](https://lovi.care/skincare/it/ingredients/adapalene) - [Glycolic acid](https://lovi.care/skincare/it/ingredients/glycolic-acid) - [Benzoyl peroxide](https://lovi.care/skincare/it/ingredients/benzoyl-peroxide) - [Vitamin C](https://lovi.care/skincare/it/ingredients/vitamin-c) - [Retinol](https://lovi.care/skincare/it/ingredients/retinol) - [Azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid) - [Panthenol](https://lovi.care/skincare/it/ingredients/panthenol) - [AHA blend glycolic and citric acids](https://lovi.care/skincare/it/ingredients/aha-blend-glycolic-and-citric-acids) - [Green tea](https://lovi.care/skincare/it/ingredients/green-tea) - [Niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide) - [Salicylic acid](https://lovi.care/skincare/it/ingredients/salicylic-acid) - [Ceramide-building complex](https://lovi.care/skincare/it/ingredients/ceramide-building-complex) - [Tretinoin](https://lovi.care/skincare/it/ingredients/tretinoin) - [Glycerin](https://lovi.care/skincare/it/ingredients/glycerin) - [Coenzyme Q10](https://lovi.care/skincare/it/ingredients/coenzyme-q10) - [Vitamin E](https://lovi.care/skincare/it/ingredients/vitamin-e) - [Bakuchiol](https://lovi.care/skincare/it/ingredients/bakuchiol) - [Silk amino acids](https://lovi.care/skincare/it/ingredients/silk-amino-acids) - [Vitamin A](https://lovi.care/skincare/it/ingredients/vitamin-a) - [Arginine](https://lovi.care/skincare/it/ingredients/arginine) - [Liposome](https://lovi.care/skincare/it/ingredients/liposome) - [Pro-retinol](https://lovi.care/skincare/it/ingredients/pro-retinol) - [Retinal](https://lovi.care/skincare/it/ingredients/retinal) - [Copper](https://lovi.care/skincare/it/ingredients/copper) - [Magnesium](https://lovi.care/skincare/it/ingredients/magnesium) - [Lactic acid](https://lovi.care/skincare/it/ingredients/lactic-acid) - [Taurine](https://lovi.care/skincare/it/ingredients/taurine) - [Mandelic acid](https://lovi.care/skincare/it/ingredients/mandelic-acid) - [Retinoid blend](https://lovi.care/skincare/it/ingredients/retinoid-blend) - [Superoxide dismutase](https://lovi.care/skincare/it/ingredients/superoxide-dismutase) - [Hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) - [Polyvinyl alcohol](https://lovi.care/skincare/it/ingredients/polyvinyl-alcohol) - [Zinc](https://lovi.care/skincare/it/ingredients/zinc) - [Zinc sulfate](https://lovi.care/skincare/it/ingredients/zinc-sulfate) - [Bleach](https://lovi.care/skincare/it/ingredients/bleach) - [Granactive retinoid](https://lovi.care/skincare/it/ingredients/granactive-retinoid) - [Hydroxypinacolone retinoate](https://lovi.care/skincare/it/ingredients/hydroxypinacolone-retinoate) - [Microcapsule](https://lovi.care/skincare/it/ingredients/microcapsule) - [Potassium hydroxide](https://lovi.care/skincare/it/ingredients/potassium-hydroxide) - [Cholesterol](https://lovi.care/skincare/it/ingredients/cholesterol) - [Phytosphingosine](https://lovi.care/skincare/it/ingredients/phytosphingosine) - [Betaine](https://lovi.care/skincare/it/ingredients/betaine) - [Phytosterol](https://lovi.care/skincare/it/ingredients/phytosterol) - [Citric acid](https://lovi.care/skincare/it/ingredients/citric-acid) - [Isopropyl alcohol](https://lovi.care/skincare/it/ingredients/isopropyl-alcohol) - [Beta-sitosterol](https://lovi.care/skincare/it/ingredients/beta-sitosterol) - [Behenyl alcohol](https://lovi.care/skincare/it/ingredients/behenyl-alcohol) - [Protease](https://lovi.care/skincare/it/ingredients/protease) - [Squalene](https://lovi.care/skincare/it/ingredients/squalene) - [Tri-ceramide complex](https://lovi.care/skincare/it/ingredients/tri-ceramide-complex) - [Baking soda](https://lovi.care/skincare/it/ingredients/baking-soda) - [GABA](https://lovi.care/skincare/it/ingredients/gaba) - [Theanine](https://lovi.care/skincare/it/ingredients/theanine) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every ingredient with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this ingredient guide: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/hexapeptide - United Kingdom: https://lovi.care/skincare/uk/ingredients/hexapeptide - Ireland: https://lovi.care/skincare/ie/ingredients/hexapeptide - Germany: https://lovi.care/skincare/de/ingredients/hexapeptide - France: https://lovi.care/skincare/fr/ingredients/hexapeptide - Italy: https://lovi.care/skincare/it/ingredients/hexapeptide (this page) - Netherlands: https://lovi.care/skincare/nl/ingredients/hexapeptide - Spain: https://lovi.care/skincare/es/ingredients/hexapeptide - Canada: https://lovi.care/skincare/ca/ingredients/hexapeptide - Australia: https://lovi.care/skincare/au/ingredients/hexapeptide - Singapore: https://lovi.care/skincare/sg/ingredients/hexapeptide - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/hexapeptide - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/hexapeptide