# Azelaic acid and hyaluronic acid

Page: https://lovi.care/skincare/it/ingredients/azelaic-acid-and-hyaluronic-acid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Keep them apart

Apply [azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid) first, wait ten to fifteen minutes, and then apply [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid), because the strong acid can break down the hydrating gel. Azelaic acid works as a strong exfoliant that can clash with the soothing moisture of hyaluronic acid and cause extra stinging or redness. The shopper can either switch to a gentler acid strength or wait longer between applying the two products.

- [All about azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid)
- [All about hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid)

### [Azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid) products

- [The Ordinary Azelaic Acid Suspension 10%](https://lovi.care/skincare/it/p/the-ordinary/azelaic-acid-suspension-10/for/acne-prone-skin) — High fit — [€12.77 at Amazon](https://www.amazon.it/dp/B0BBLZ2YBP?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Paula's Choice 10% Azelaic Acid Booster](https://lovi.care/skincare/it/p/paula-s-choice/10-azelaic-acid-booster/for/acne-prone-skin) — High fit — [€49.00 at Amazon](https://www.amazon.it/dp/B09S9R72XB?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Topicals Faded Serum](https://lovi.care/skincare/it/p/topicals/faded-serum/for/oily-acne-prone-skin) — Superior fit — [€10.99 at Amazon](https://www.amazon.it/dp/B0D5YH4XQ5?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Musely The Spot Cream](https://lovi.care/skincare/it/p/musely/the-spot-cream/for/mature-skin) — High fit
- [Topicals Faded Brightening & Clearing Serum](https://lovi.care/skincare/it/p/topicals/faded-brightening-and-clearing-serum/for/acne-prone-skin) — High fit
- [Bioderma Pigmentbio Sensitive Areas](https://lovi.care/skincare/it/p/bioderma/pigmentbio-sensitive-areas/for/oily-acne-prone-skin) — High fit — [€39.70 at Notino](https://www.notino.it/bioderma/pigmentbio-sensitive-areas-crema-sbiancante-per-viso-e-punti-sensibili/p-16277872/)
- [Peach Slices Redness Relief Azelaic Acid Serum](https://lovi.care/skincare/it/p/peach-slices/redness-relief-azelaic-acid-serum/for/sensitive-skin) — High fit
- [Finacea Gel](https://lovi.care/skincare/it/p/finacea/gel/for/oily-acne-prone-skin) — High fit
- [NATURIUM Azelaic Acid Emulsion 10%](https://lovi.care/skincare/it/p/naturium/azelaic-acid-emulsion-10/for/acne-prone-skin) — High fit
- [StriVectin Daily Reveal Exfoliating Pads](https://lovi.care/skincare/it/p/strivectin/daily-reveal-exfoliating-pads/for/oily-skin) — Average fit — [€26.90 at Notino](https://www.notino.it/strivectin/advanced-resurfacing-daily-reveal-exfoliating-pads-dischetti-esfolianti-per-lisciare-la-pelle-e-ridurre-i-pori/p-16092709/)
- [The INKEY List 10% Azelaic Acid Serum](https://lovi.care/skincare/it/p/the-inkey-list/10-azelaic-acid-serum/for/combination-skin) — Superior fit — [€13.99 at Amazon](https://www.amazon.it/dp/B0BW3SWJQK?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Drunk Elephant Bouncy Brightfacial](https://lovi.care/skincare/it/p/drunk-elephant/bouncy-brightfacial/for/oily-acne-prone-skin) — High fit

### [Hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) products

- [CeraVe Moisturising Cream](https://lovi.care/skincare/it/p/cerave/moisturising-cream/for/dry-sensitive-skin) — Superior fit — [€12.89 at Amazon](https://www.amazon.it/dp/B07CH9XWHR?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [€9.19 at Amazon](https://www.amazon.it/dp/B07C5R51Q9?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Rhode Glazing Milk](https://lovi.care/skincare/it/p/rhode/glazing-milk/for/dry-skin) — Superior fit
- [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€24.75 at Amazon](https://www.amazon.it/dp/B0CRSJ46YD?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Vanicream Daily Facial Moisturizer](https://lovi.care/skincare/it/p/vanicream/daily-facial-moisturizer/for/dry-skin) — Superior fit
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/it/p/cosrx/advanced-snail-96-mucin-power-essence/for/dry-skin) — Superior fit — [€12.09 at Amazon](https://www.amazon.it/dp/B00PBX3L7K?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Dr. Althea 345 Relief Cream](https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [€21.80 at Amazon](https://www.amazon.it/dp/B07PK2P2XB?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/it/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.it/dp/B0DT18YRT9?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Neutrogena Hydro Boost Water Gel](https://lovi.care/skincare/it/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [€14.95 at Amazon](https://www.amazon.it/dp/B0CZS2H7LB?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/it/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [€51.95 at Amazon](https://www.amazon.it/dp/B007M81B4M?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [CeraVe Daily Moisturizing Lotion](https://lovi.care/skincare/it/p/cerave/daily-moisturizing-lotion/for/dry-skin) — Superior fit — [€10.19 at Amazon](https://www.amazon.it/dp/B07CG2TD9F?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [CeraVe Healing Ointment](https://lovi.care/skincare/it/p/cerave/healing-ointment/for/dry-skin) — High fit

## Questions and answers

### Can you use azelaic acid and hyaluronic acid together?

Keep [azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid) and [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) apart in your routine, as combining them may increase irritation and disrupt the hydration film. Apply your acid first, and wait 10 to 15 minutes before applying your hyaluronic acid, or use products like Anua Azelacic Acid 10 + Hyaluron separately.

### Which goes first, azelaic acid or hyaluronic acid?

Keep azelaic acid and hyaluronic acid apart in your routine, or apply azelaic acid first and follow with hyaluronic acid after 10 to 15 minutes. Combining them directly may increase irritation and disrupt the hydration film.

### Are azelaic acid and hyaluronic acid good for sensitive skin?

Keep azelaic acid and hyaluronic acid apart because combining them may increase irritation and disrupt the hydration film, especially on sensitive skin. Products like Anua Azelacic Acid 10 + Hyaluron contain both ingredients, but separating them into different routines or waiting 10 to 15 minutes helps prevent sensitivity.

## Research on azelaic acid and hyaluronic acid

- [Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects](https://pubmed.ncbi.nlm.nih.gov/30287361/) Hyaluronic acid · International Journal of Biological Macromolecules, 2018
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Hyaluronic acid · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Liposome, gel and lipogelosome formulations containing sodium hyaluronate](https://pubmed.ncbi.nlm.nih.gov/24724824/) Hyaluronic acid · Journal of Liposome Research, 2014
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hyaluronic acid · Dermatologic Therapy, 2022
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022

## Other combinations

- Work well together: [Acetyl hexapeptide-3 and hyaluronic acid](https://lovi.care/skincare/it/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid)
- Work well together: [Bio-placenta peptides and hyaluronic acid](https://lovi.care/skincare/it/ingredients/bio-placenta-peptides-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and collagen peptide](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-collagen-peptide)
- Work well together: [Hyaluronic acid and copper peptide](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-copper-peptide)
- Work well together: [Hexapeptide and hyaluronic acid](https://lovi.care/skincare/it/ingredients/hexapeptide-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-hexapeptide-9)
- Work well together: [Hyaluronic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-palmitoyl-pentapeptide-4)
- Work well together: [Hyaluronic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-palmitoyl-tripeptide-1)
- Work well together: [Hyaluronic acid and peptide-rich plasma](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-peptide-rich-plasma)
- Work well together: [Hyaluronic acid and triple peptide blend](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-triple-peptide-blend)
- Work well together: [Gluconolactone and hyaluronic acid](https://lovi.care/skincare/it/ingredients/gluconolactone-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and lactobionic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-lactobionic-acid)
- Work well together: [Hyaluronic acid and ascorbyl glucoside](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-ascorbyl-glucoside)
- Work well together: [Coenzyme Q10 and hyaluronic acid](https://lovi.care/skincare/it/ingredients/coenzyme-q10-and-hyaluronic-acid)
- Work well together: [Vitamin E and hyaluronic acid](https://lovi.care/skincare/it/ingredients/vitamin-e-and-hyaluronic-acid)
- Depends on the strength: [AHA blend glycolic and citric acids and hyaluronic acid](https://lovi.care/skincare/it/ingredients/aha-blend-glycolic-and-citric-acids-and-hyaluronic-acid)
- Depends on the strength: [Hyaluronic acid and citric acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-citric-acid)
- Depends on the strength: [Glycolic acid and hyaluronic acid](https://lovi.care/skincare/it/ingredients/glycolic-acid-and-hyaluronic-acid)
- Depends on the strength: [Lactic acid and hyaluronic acid](https://lovi.care/skincare/it/ingredients/lactic-acid-and-hyaluronic-acid)
- Depends on the strength: [Mandelic acid and hyaluronic acid](https://lovi.care/skincare/it/ingredients/mandelic-acid-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and tri-ceramide complex](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and hyaluronic acid](https://lovi.care/skincare/it/ingredients/salicylic-acid-and-hyaluronic-acid)
- Work well together: [Niacinamide and hyaluronic acid](https://lovi.care/skincare/it/ingredients/niacinamide-and-hyaluronic-acid)
- Keep them apart: [Hyaluronic acid and bergamot oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-bergamot-oil)
- Keep them apart: [Hyaluronic acid and camphor oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-camphor-oil)
- Keep them apart: [Hyaluronic acid and chamomile oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-chamomile-oil)
- Keep them apart: [Hyaluronic acid and clove leaf oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-clove-leaf-oil)
- Keep them apart: [Hyaluronic acid and eucalyptus oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-eucalyptus-oil)
- Keep them apart: [Hyaluronic acid and geranium oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-geranium-oil)
- Keep them apart: [Hyaluronic acid and grapefruit peel oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-grapefruit-peel-oil)
- Keep them apart: [Lavender oil and hyaluronic acid](https://lovi.care/skincare/it/ingredients/lavender-oil-and-hyaluronic-acid)
- Keep them apart: [Hyaluronic acid and lemon oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-lemon-oil)
- Keep them apart: [Hyaluronic acid and orange oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-orange-oil)
- Keep them apart: [Hyaluronic acid and palmarosa oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-palmarosa-oil)
- Keep them apart: [Hyaluronic acid and peppermint oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-peppermint-oil)
- Keep them apart: [Hyaluronic acid and rose oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-rose-oil)
- Keep them apart: [Hyaluronic acid and rosewood oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-rosewood-oil)
- Keep them apart: [Hyaluronic acid and sandalwood oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-sandalwood-oil)
- Keep them apart: [Tea tree oil and hyaluronic acid](https://lovi.care/skincare/it/ingredients/tea-tree-oil-and-hyaluronic-acid)
- Keep them apart: [Hyaluronic acid and thyme oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-thyme-oil)
- Keep them apart: [Hyaluronic acid and wild mint oil](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-wild-mint-oil)
- Work well together: [Hyaluronic acid and cholesterol](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-cholesterol)
- Work well together: [Hyaluronic acid and lauric acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-lauric-acid)
- Work well together: [Linoleic acid and hyaluronic acid](https://lovi.care/skincare/it/ingredients/linoleic-acid-and-hyaluronic-acid)
- Keep them apart: [Hyaluronic acid and isopropyl alcohol](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-isopropyl-alcohol)
- Keep them apart: [Azelaic acid and aha blend glycolic and citric acids](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-aha-blend-glycolic-and-citric-acids)
- Keep them apart: [Azelaic acid and citric acid](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-citric-acid)
- Keep them apart: [Glycolic acid and azelaic acid](https://lovi.care/skincare/it/ingredients/glycolic-acid-and-azelaic-acid)
- Keep them apart: [Azelaic acid and lactic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-lactic-acid)
- Keep them apart: [Azelaic acid and mandelic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-mandelic-acid)
- Keep them apart: [Azelaic acid and salicylic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-salicylic-acid)
- Work well together: [Arginine and hyaluronic acid](https://lovi.care/skincare/it/ingredients/arginine-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and GABA](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-gaba)
- Work well together: [Silk amino acids and hyaluronic acid](https://lovi.care/skincare/it/ingredients/silk-amino-acids-and-hyaluronic-acid)
- Work well together: [Taurine and hyaluronic acid](https://lovi.care/skincare/it/ingredients/taurine-and-hyaluronic-acid)
- Work well together: [Hyaluronic acid and theanine](https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-theanine)
- Work well together: [Panthenol and hyaluronic acid](https://lovi.care/skincare/it/ingredients/panthenol-and-hyaluronic-acid)
- Work well together: [Vitamin C and hyaluronic acid](https://lovi.care/skincare/it/ingredients/vitamin-c-and-hyaluronic-acid)
- Keep them apart: [Azelaic acid and acetyl hexapeptide-3](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Azelaic acid and bio-placenta peptides](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-bio-placenta-peptides)
- Keep them apart: [Azelaic acid and collagen peptide](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-collagen-peptide)
- Keep them apart: [Azelaic acid and copper peptide](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-copper-peptide)
- Keep them apart: [Azelaic acid and hexapeptide](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-hexapeptide)
- Keep them apart: [Azelaic acid and hexapeptide-9](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-hexapeptide-9)
- Keep them apart: [Azelaic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Azelaic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Azelaic acid and peptide-rich plasma](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-peptide-rich-plasma)
- Keep them apart: [Azelaic acid and triple peptide blend](https://lovi.care/skincare/it/ingredients/azelaic-acid-and-triple-peptide-blend)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/azelaic-acid-and-hyaluronic-acid
- United Kingdom: https://lovi.care/skincare/uk/ingredients/azelaic-acid-and-hyaluronic-acid
- Ireland: https://lovi.care/skincare/ie/ingredients/azelaic-acid-and-hyaluronic-acid
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