# The Ordinary vs Medik8

Page: https://lovi.care/skincare/it/compare/the-ordinary-vs-medik8

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

The Ordinary and Medik8 are skincare brands founded in Canada in 2016 and Britain in 2009, respectively. The Canadian brand offers [serums](https://lovi.care/skincare/it/ingredients/serum), moisturizers, cleansers, and toners built around [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid), [glycerin](https://lovi.care/skincare/it/ingredients/glycerin), and squalane, while the British brand provides serums, moisturizers, eye products, and toners built around hyaluronic acid. Both suit dry skin and sensitive skin best, but they differ in their specific formulations and targeted treatments for acne-prone skin, dark spots, and mature skin.

The Ordinary is a Canadian skincare brand founded in 2016 and owned by The Estée Lauder Companies Inc. since 2021.

[glossy.co](https://www.glossy.co/beauty/estee-lauder-companies-completes-acquisition-of-deciem-the-ordinary-niod-for-1-7-billion/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Brandon_Truaxe)

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular The Ordinary and Medik8 products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg8d7bf36ede).

### Popular The Ordinary vs Medik8 products

#### The Ordinary

- [Azelaic Acid Suspension 10%](https://lovi.care/skincare/it/p/the-ordinary/azelaic-acid-suspension-10/for/acne-prone-skin) — High fit — [€12.77 at Amazon](https://www.amazon.it/dp/B0BBLZ2YBP?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Acid 2% + B5](https://lovi.care/skincare/it/p/the-ordinary/hyaluronic-acid-2-b5/for/acne-prone-skin) — High fit — [€9.80 at Amazon](https://www.amazon.it/dp/B01MYEZPC8?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Glycolic Acid 7% Toning Solution](https://lovi.care/skincare/it/p/the-ordinary/glycolic-acid-7-toning-solution/for/combination-skin) — Superior fit — [€13.30 at Amazon](https://www.amazon.it/dp/B071914GGL?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Salicylic Acid 2% Solution](https://lovi.care/skincare/it/p/the-ordinary/salicylic-acid-2-solution/for/dry-skin) — Average fit — [€7.02 at Lookfantastic](https://www.lookfantastic.it/p/the-ordinary-salicylic-acid-2-solution-30ml/13754943/)
- [Multi-Peptide + Copper Peptides 1% Serum](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin) — High fit — [€30.99 at Amazon](https://www.amazon.it/dp/B0C9DXGXZ3?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/it/p/the-ordinary/niacinamide-10-zinc-1/for/oily-skin) — Superior fit — [€5.75 at Lookfantastic](https://www.lookfantastic.it/p/the-ordinary-niacinamide-10-zinc-1-serum-30ml/13187076/)
- [Mandelic Acid 10% + HA](https://lovi.care/skincare/it/p/the-ordinary/mandelic-acid-10-ha/for/acne-prone-skin) — Superior fit — [€9.00 at Notino](https://www.notino.it/the-ordinary/mandelic-acid-10-ha-siero-esfoliante-levigante/p-16204765/)
- [AHA 30% + BHA 2% Peeling Solution](https://lovi.care/skincare/it/p/the-ordinary/aha-30-bha-2-peeling-solution/for/oily-acne-prone-skin) — Superior fit — [€10.24 at Lookfantastic](https://www.lookfantastic.it/p/the-ordinary-aha-30-bha-2-peeling-solution-30ml/11429304/)

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/it/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [€109.17 at Amazon](https://www.amazon.it/dp/B0DSJNWVV6?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/it/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [€89.00 at Amazon](https://www.amazon.it/dp/B07Y5P314G?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/it/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [€65.67 at Amazon](https://www.amazon.it/dp/B094GHRY9B?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/it/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [€94.58 at Amazon](https://www.amazon.it/dp/B0DWMZCJSW?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/it/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [€53.00 at Lookfantastic](https://www.lookfantastic.it/p/medik8-crystal-retinal-ceramide-eye-3-15ml/14271143/)
- [Oxy-R Peptides](https://lovi.care/skincare/it/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [€75.90 at Notino](https://www.notino.it/medik8/oxy-r-peptides-siero-intenso/p-16151739/)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/it/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [€63.24 at Amazon](https://www.amazon.it/dp/B0CVBM45QZ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Hydr8 B5 Intense](https://lovi.care/skincare/it/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [€58.00 at Amazon](https://www.amazon.it/dp/B0BRQGHCYJ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

## People Say

The Ordinary

Medik8

- Texture and Pores Mostly Mentioned Often Mentioned “glass skin effect — The Ordinary Glycolic Acid 7% Toning Solution” “pores look significantly smaller — The Ordinary Niacinamide 10% + Zinc 1%” “smoother skin — Medik8 Surface Radiance Cleanse” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic”
- Gentle and Non-Irritating Formula Sometimes Noted Mostly Mentioned “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “never had any reaction to it with my sensitive skin — The Ordinary Mandelic Acid 10% + HA”
- Texture and Absorption (Lightweight/Elegant) Often Mentioned Often Mentioned “Sinks in immediately — The Ordinary Natural Moisturizing Factors + HA” “Sinks in immediately — The Ordinary Multi-Peptide + Copper Peptides 1% Serum” “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream” “Absorbs fast — Medik8 Liquid Peptides”
- Hydration and Moisture Often Mentioned Often Mentioned “Restores moisture — Medik8 Liquid Peptides” “Instantly quenched the skin — Medik8 Hydr8 B5 Intense” “Plumps skin with moisture — Medik8 Bakuchiol Peptides” “skin feels immediately hydrated — The Ordinary Hyaluronic Acid 2% + B5”
- Value and Pricing Mostly Mentioned Rarely Noted “lasts forever — The Ordinary Glycolic Acid 7% Toning Solution” “can't beat the price — The Ordinary Salicylic Acid 2% Solution” “extremely affordable — The Ordinary Niacinamide 10% + Zinc 1%” “better value than Skinceuticals — Medik8 Super C Ferulic”
- Brightening and Dark Spots Sometimes Noted Often Mentioned “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum” “pigmentation lightened slightly — Medik8 Oxy-R Peptides” “Dark spots have faded noticeably — The Ordinary Alpha Arbutin 2% + HA”
- Other Minor Complaints and Performance Issues Mostly Mentioned Often Mentioned “too oily for my combination skin — Medik8 C-Tetra Serum” “Not as effective as retinol — Medik8 Bakuchiol Peptides” “no difference — Medik8 Oxy-R Peptides” “foams up like soap — The Ordinary Salicylic Acid 2% Solution”
- Pilling and Makeup Compatibility Often Mentioned Rarely Noted “Didn't mix well with my foundation — Medik8 Hydr8 B5 Intense” “crumbles and piles under moisturizer — The Ordinary Azelaic Acid Suspension 10%”
- Skin Irritation and Burning Often Mentioned Sometimes Noted “stinging sensation — Medik8 Super C Ferulic” “caused slight redness — Medik8 Crystal Retinal Ceramide Eye 3” “Caused stinging and redness — Medik8 Press & Glow” “irritated AF the next day — The Ordinary AHA 30% + BHA 2% Peeling Solution”

### The Ordinary vs Medik8 routines for dry skin

#### Medik8-focused routine

- Cleanser: [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [€9.19 at Amazon](https://www.amazon.it/dp/B07C5R51Q9?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [€15.16 at Amazon](https://www.amazon.it/dp/B08Q6WZ6J1?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/it/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [€58.00 at Amazon](https://www.amazon.it/dp/B0BRQGHCYJ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [€37.19 at Amazon](https://www.amazon.it/dp/B00JJZN1HG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/it/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€15.90 at Amazon](https://www.amazon.it/dp/B084Q16G8D?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Bakuchiol Peptides](https://lovi.care/skincare/it/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [€94.58 at Amazon](https://www.amazon.it/dp/B0DWMZCJSW?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/it/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [€31.93 at Amazon](https://www.amazon.it/dp/B0BLXHYKTX?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### The Ordinary-focused routine

- Cleanser: [Glycolipid Cream Cleanser](https://lovi.care/skincare/it/p/the-ordinary/glycolipid-cream-cleanser/for/dry-skin) — Superior fit — [€12.77 at Lookfantastic](https://www.lookfantastic.it/p/the-ordinary-glycolipid-cream-cleanser-150ml/14293489/) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [€15.16 at Amazon](https://www.amazon.it/dp/B08Q6WZ6J1?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Natural Moisturizing Factors + HA](https://lovi.care/skincare/it/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-skin) — Superior fit — [€13.11 at Amazon](https://www.amazon.it/dp/B07N74F8NP?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [€37.19 at Amazon](https://www.amazon.it/dp/B00JJZN1HG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/it/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€15.90 at Amazon](https://www.amazon.it/dp/B084Q16G8D?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Mandelic Acid 10% + HA](https://lovi.care/skincare/it/p/the-ordinary/mandelic-acid-10-ha/for/dry-skin) — Superior fit — [€9.00 at Notino](https://www.notino.it/the-ordinary/mandelic-acid-10-ha-siero-esfoliante-levigante/p-16204765/) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/it/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [€31.93 at Amazon](https://www.amazon.it/dp/B0BLXHYKTX?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 99% fit](https://lovi.care/skincare/it/skin/dry-skin)

### The Ordinary vs Medik8 routines for oily skin

#### The Ordinary-focused routine

- Cleanser: [Glucoside Foaming Cleanser](https://lovi.care/skincare/it/p/the-ordinary/glucoside-foaming-cleanser/for/oily-skin) — High fit — [€12.77 at Amazon](https://www.amazon.it/dp/B0BYQ45N7W?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Natural Moisturizing Factors + HA](https://lovi.care/skincare/it/p/the-ordinary/natural-moisturizing-factors-ha/for/oily-skin) — High fit — [€13.11 at Amazon](https://www.amazon.it/dp/B07N74F8NP?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Glycolic Acid 7% Toning Solution](https://lovi.care/skincare/it/p/the-ordinary/glycolic-acid-7-toning-solution/for/oily-skin) — High fit — [€13.30 at Amazon](https://www.amazon.it/dp/B071914GGL?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/it/p/the-ordinary/niacinamide-10-zinc-1/for/oily-skin) — Superior fit — [€5.75 at Lookfantastic](https://www.lookfantastic.it/p/the-ordinary-niacinamide-10-zinc-1-serum-30ml/13187076/) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Salicylic Acid 2% Masque](https://lovi.care/skincare/it/p/the-ordinary/salicylic-acid-2-masque/for/oily-skin) — High fit — [€15.00 at Amazon](https://www.amazon.it/dp/B0BSSCJMF2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Medik8-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€24.75 at Amazon](https://www.amazon.it/dp/B0CRSJ46YD?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/it/p/medik8/hydr8-b5-intense/for/oily-skin) — High fit — [€58.00 at Amazon](https://www.amazon.it/dp/B0BRQGHCYJ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/it/p/medik8/press-and-glow/for/oily-skin) — Average fit — [€83.00 at Amazon](https://www.amazon.it/dp/B0BHX9PXBQ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/it/p/medik8/oxy-r-peptides/for/oily-skin) — High fit — [€75.90 at Notino](https://www.notino.it/medik8/oxy-r-peptides-siero-intenso/p-16151739/) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/it/skin/oily-skin)

### The Ordinary vs Medik8 routines for combination skin

#### The Ordinary-focused routine

- Cleanser: [Glucoside Foaming Cleanser](https://lovi.care/skincare/it/p/the-ordinary/glucoside-foaming-cleanser/for/combination-skin) — High fit — [€12.77 at Amazon](https://www.amazon.it/dp/B0BYQ45N7W?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Natural Moisturizing Factors + HA](https://lovi.care/skincare/it/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — [€13.11 at Amazon](https://www.amazon.it/dp/B07N74F8NP?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Glycolic Acid 7% Toning Solution](https://lovi.care/skincare/it/p/the-ordinary/glycolic-acid-7-toning-solution/for/combination-skin) — Superior fit — [€13.30 at Amazon](https://www.amazon.it/dp/B071914GGL?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Mandelic Acid 10% + HA](https://lovi.care/skincare/it/p/the-ordinary/mandelic-acid-10-ha/for/combination-skin) — Superior fit — [€9.00 at Notino](https://www.notino.it/the-ordinary/mandelic-acid-10-ha-siero-esfoliante-levigante/p-16204765/) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Salicylic Acid 2% Masque](https://lovi.care/skincare/it/p/the-ordinary/salicylic-acid-2-masque/for/combination-skin) — High fit — [€15.00 at Amazon](https://www.amazon.it/dp/B0BSSCJMF2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Medik8-focused routine

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — [€13.50 at Amazon](https://www.amazon.it/dp/B07RY6Q6QM?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/it/p/medik8/hydr8-b5-intense/for/combination-skin) — High fit — [€58.00 at Amazon](https://www.amazon.it/dp/B0BRQGHCYJ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/it/p/medik8/press-and-glow/for/combination-skin) — High fit — [€83.00 at Amazon](https://www.amazon.it/dp/B0BHX9PXBQ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/it/p/medik8/oxy-r-peptides/for/combination-skin) — High fit — [€75.90 at Notino](https://www.notino.it/medik8/oxy-r-peptides-siero-intenso/p-16151739/) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/it/skin/combination-skin)

## Questions and answers

### The Ordinary or Medik8: which is better?

Both The Ordinary and Medik8 are great choices, but The Ordinary offers better value, while Medik8 provides more luxurious hydration and brightening. [Hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) helps maintain skin moisture.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between The Ordinary and Medik8?

The Ordinary offers better value and pricing, whereas Medik8 is noted for providing superior hydration, brightening, and gentle formulas. Both brands feature products that help improve skin texture and maintain moisture.

### The Ordinary or Medik8 for dry skin?

Both The Ordinary and Medik8 have a Superior routine fit for dry skin. The Ordinary products on this page help deliver great value and deep hydration.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### The Ordinary or Medik8: which cleanser is better?

Both The Ordinary and Medik8 offer great cleansers, with The Ordinary focusing on budget-friendly value and Medik8 providing targeted results like the acne-clearing Surface Radiance Cleanse. The products on this page show that both brands cater well to various skin types through gentle formulations.

### Which is more affordable, The Ordinary or Medik8?

The Ordinary is more affordable, offering affordable and great value [serums](https://lovi.care/skincare/it/ingredients/serum) on the products on this page.

### Which brand has more fragrance-free products, The Ordinary or Medik8?

The Ordinary has more fragrance-free products than Medik8, as every product on The Ordinary page lists no fragrance in its ingredients while Medik8 has 11 of 12 fragrance-free products.

### How do the ownership and founding dates of The Ordinary and Medik8 compare?

The Ordinary was founded in Canada in 2016 and is owned by The Estée Lauder Companies Inc. In contrast, Medik8 was founded in the United Kingdom in 2009 and is owned by L'Oréal Groupe.

### Which brand performs better for brightening and dark spots according to reviewers?

Medik8 performs better for brightening and dark spots according to reviewers. The Ordinary products on this page also offer dark spot fading serums.

### The Ordinary or Medik8 for oily skin?

For oily skin, The Ordinary has a Superior routine fit while Medik8 has a High routine fit. The Ordinary offers better value and pricing, whereas Medik8 provides stronger hydration and moisture.

### The Ordinary or Medik8: which moisturizer is better?

Both The Ordinary and Medik8 offer great moisturizers, with The Ordinary providing better value and Medik8 delivering superior hydration. Hyaluronic acid helps maintain skin moisture across the products on this page.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### The Ordinary or Medik8 for sensitive skin?

Both The Ordinary and Medik8 provide a Superior routine fit for sensitive skin. The products on this page for both brands help provide gentle care, though Medik8 is specifically noted by reviewers for having a gentle and non-irritating formula.

### The Ordinary or Medik8 for acne-prone skin?

The Ordinary is a better fit for acne-prone skin, offering a Superior routine compared to Medik8's High level. The Ordinary products on this page help with acne-clearing serums and provide a more affordable value.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress](https://pubmed.ncbi.nlm.nih.gov/11181450/) Egcg epigallocatechin gallate · Carcinogenesis, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf water · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Vitamin c derivative · Experimental Dermatology, 2003
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside, Vitamin c derivative · Journal of Periodontology, 2009
- [Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin](https://pubmed.ncbi.nlm.nih.gov/28123324/) Panax ginseng root extract · Journal of Ginseng Research, 2017
- [Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women](https://pubmed.ncbi.nlm.nih.gov/25378941/) Oxidized glutathione · Clinical, Cosmetic and Investigational Dermatology, 2014
- [Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling](https://pubmed.ncbi.nlm.nih.gov/16890388/) Panax ginseng root extract · Journal of Ethnopharmacology, 2007
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Asiaticoside, Madecassic acid · Indian Journal of Pharmaceutical Sciences, 2016
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Sphingolipids, Phytoceramides · Scientific Reports, 2022
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Glycolipid biosurfactants, mannosylerythritol lipids, show antioxidant and protective effects against H(2)O(2)-induced oxidative stress in cultured human skin fibroblasts](https://pubmed.ncbi.nlm.nih.gov/22864517/) Glycolipids · Journal of Oleo Science, 2012
- [Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin](https://pubmed.ncbi.nlm.nih.gov/27349297/) Xylitol, Xylitylglucoside · Acta Dermato-venereologica, 2017
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Characterisation of cytotoxicity and immunomodulatory effects of glycolipid biosurfactants on human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/36441210/) Glycolipids · Applied Microbiology and Biotechnology, 2023
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration](https://pubmed.ncbi.nlm.nih.gov/25143733/) Argania spinosa kernel oil · International Journal of Nanomedicine, 2014
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The moisturizing effects of glycolipid biosurfactants, mannosylerythritol lipids, on human skin](https://pubmed.ncbi.nlm.nih.gov/22790172/) Glycolipids · Journal of Oleo Science, 2012
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassic acid · Journal of Alternative and Complementary Medicine, 2020
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine · The British Journal of Dermatology, 2010
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Double-blind, randomized, placebo-controlled study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/17635508/) Ethyl linoleate · The British Journal of Dermatology, 2007
- [Characterization of Acne-Prone Skin with Reflectance Confocal Microscopy and Optical Coherence Tomography and Modifications Induced by Topical Treatment and Probiotic Supplementation](https://pubmed.ncbi.nlm.nih.gov/37510902/) Hydroxypinacolone retinoate · Journal of Clinical Medicine, 2023
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2021
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [High-Payload Nanosuspension of Centella asiatica Extract for Improved Skin Delivery with No Irritation](https://pubmed.ncbi.nlm.nih.gov/34764648/) Asiaticoside · International Journal of Nanomedicine, 2021
- [Comparative Study of 35% Glycolic Acid, 20% Salicylic-10% Mandelic Acid, and Phytic Acid Combination Peels in the Treatment of Active Acne and Postacne Pigmentation](https://pubmed.ncbi.nlm.nih.gov/31619887/) Phytic acid · Journal of Cutaneous and Aesthetic Surgery, 2019
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes: Invitro and invivo human studies](https://pubmed.ncbi.nlm.nih.gov/37681127/) Alpha-arbutin, Alpha arbutin · Heliyon, 2023
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Evaluating the Safety and Efficacy of a Topical Formulation Containing Epidermal Growth Factor, Tranexamic Acid, Vitamin C, Arbutin, Niacinamide and Other Ingredients as Hydroquinone 4% Alternatives to Improve Hyperpigmentation: A Prospective, Randomized, Controlled Split Face Study](https://pubmed.ncbi.nlm.nih.gov/33022197/) Alpha arbutin · Journal of Cosmetic Science, 2020
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Lycopene and Melatonin: Antioxidant Compounds in Cosmetic Formulations](https://pubmed.ncbi.nlm.nih.gov/33070140/) Solanum lycopersicum fruit extract tomato fruit extract · Skin Pharmacology and Physiology, 2020
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary results of a 2-month prospective study](https://pubmed.ncbi.nlm.nih.gov/32869963/) Granactive retinoid · Giornale Italiano Di Dermatologia E Venereologia, 2020
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Efficacy of ceramides and niacinamide-containing moisturizer versus hydrophilic cream in combination with topical anti-acne treatment in mild to moderate acne vulgaris: A split face, double-blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/38299457/) Phytoceramides · Journal of Cosmetic Dermatology, 2024
- [Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging](https://pubmed.ncbi.nlm.nih.gov/30373163/) Pentylene glycol · International Journal of Molecular Sciences, 2018
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Permeation, metabolism and site of action concentration of nicotinic acid derivatives in human skin. Correlation with topical pharmacological effect](https://pubmed.ncbi.nlm.nih.gov/14550884/) Hexyl nicotinate · European Journal of Pharmaceutical Sciences, 2003
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Panthenyl triacetate transformation, stimulation of metabolic pathways, and wound-healing properties in the human skin](https://pubmed.ncbi.nlm.nih.gov/22487447/) Panthenyl triacetate · Journal of Cosmetic Science, 2012
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Evaluation of wound healing potential of new composite liposomal films containing coenzyme Q10 and d-panthenyl triacetate as combinational treatment](https://pubmed.ncbi.nlm.nih.gov/33583320/) Panthenyl triacetate · Pharmaceutical Development and Technology, 2021
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Topical lycopene emulgel significantly improves biophysical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/36283632/) Solanum lycopersicum fruit extract tomato fruit extract · European Journal of Pharmaceutics and Biopharmaceutics, 2022
- [A randomized controlled study to evaluate the depigmenting activity of L-ascorbic acid plus phytic acid-serum vs. placebo on solar lentigines](https://pubmed.ncbi.nlm.nih.gov/22151934/) Phytic acid · Journal of Cosmetic Dermatology, 2011
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid, Hydrolyzed sodium hyaluronate · Aesthetic Plastic Surgery, 2026
- [Hexyl-nicotinate-induced vasodilation in normal human skin](https://pubmed.ncbi.nlm.nih.gov/3582710/) Hexyl nicotinate · Dermatologica, 1987
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol, Xylitol · Molecules, 2021
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2022
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Tasmannia lanceolata leaf extract alleviates stretch mark appearance in a randomized, placebo-controlled clinical trial in women and stimulates extracellular matrix synthesis in ex vivo human skin explants](https://pubmed.ncbi.nlm.nih.gov/33048421/) Tasmannia lanceolata leaf extract fruit · Journal of Cosmetic Dermatology, 2021
- [The effects of topically applied hexyl nicotinate lotion on the cutaneous blood flow in patients with Raynaud's phenomenon](https://pubmed.ncbi.nlm.nih.gov/3203071/) Hexyl nicotinate · The British Journal of Dermatology, 1988
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties](https://pubmed.ncbi.nlm.nih.gov/39617635/) Glycolipids · International Journal of Cosmetic Science, 2025
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [A bioactive complex to protect proteins from UV-induced oxidation in human epidermis](https://pubmed.ncbi.nlm.nih.gov/19818086/) Panthenyl triacetate · International Journal of Cosmetic Science, 2010
- [Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs](https://pubmed.ncbi.nlm.nih.gov/36992949/) Ethyl linoleate · JID Innovations, 2023
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study](https://pubmed.ncbi.nlm.nih.gov/36769815/) Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2023
- [Preliminary evaluation of a comprehensive skincare regimen for enhancing skin health following advanced optimal pulse technology (AOPT) treatment](https://pubmed.ncbi.nlm.nih.gov/40497421/) Ergothioneine · International Journal of Cosmetic Science, 2025
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects](https://pubmed.ncbi.nlm.nih.gov/31347768/) Arginine · Journal of Cosmetic Dermatology, 2020
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream](https://pubmed.ncbi.nlm.nih.gov/38443132/) Moisturizing factors · Journal of Drugs in Dermatology, 2024
- [Salicylic acid peel incorporating triethyl citrate and ethyl linoleate in the treatment of moderate acne: a new therapeutic approach](https://pubmed.ncbi.nlm.nih.gov/23627892/) Ethyl linoleate · Dermatologic Surgery, 2013
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Saccharomyces ferment filtrate · Skinmed, 2021
- [Ergothioneine, collagen peptides, and sodium hyaluronate ameliorate facial skin aging via modulating oxidative stress, inflammation, and extracellular matrix homeostasis](https://pubmed.ncbi.nlm.nih.gov/42698538/) Ergothioneine · Frontiers in Nutrition, 2026
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Preclinical Safety Evaluation of Dual Drug-Loaded Nanolipidic Carriers of Dissolvable Patches: In-Vitro and In-Vivo Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/41186117/) Tetrahydrodiferuloylmethane · Molecular Pharmaceutics, 2025
- [Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment](https://pubmed.ncbi.nlm.nih.gov/39339231/) Euterpe oleracea fruit extract · Pharmaceutics, 2024

## The brands

- Canadian skincare: [The Ordinary](https://lovi.care/skincare/it/brands/the-ordinary)
- British skincare: [Medik8](https://lovi.care/skincare/it/brands/medik8)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- Spain: https://lovi.care/skincare/es/compare/the-ordinary-vs-medik8
- Canada: https://lovi.care/skincare/ca/compare/the-ordinary-vs-medik8
- Australia: https://lovi.care/skincare/au/compare/the-ordinary-vs-medik8
- Singapore: https://lovi.care/skincare/sg/compare/the-ordinary-vs-medik8
- Saudi Arabia: https://lovi.care/skincare/sa/compare/the-ordinary-vs-medik8
- United Arab Emirates: https://lovi.care/skincare/ae/compare/the-ordinary-vs-medik8