Skintific and ISDIN are established skincare lines offering effective, thoughtfully balanced formulas across a variety of daily remedies. Skintific is loved for its moisturizers, serums , and sunscreens that suit all skin types best, featuring standouts like the All Day Light Sunscreen Mist for acne-prone skin, the 5X Ceramide Barrier Moisture Gel for skin with dark spots, and the MUGWORT for mature skin. Conversely, the Spanish brand ISDIN is known for its elegant moisturizers, advanced sunscreens, restorative serums, and targeted eye products that suit dry skin and sensitive skin best, with key solutions such as the Fusion Water for acne-prone skin, the Eryfotona Actinica for skin with dark spots, and the K-Ox Eyes for mature skin. While both deliver reliable daily support to maintain a healthy and balanced complexion, they differ primarily in their optimal skin compatibility and foundational origins.
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
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This page compares some of the most popular Skintific and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app .
Popular Skintific vs ISDIN products
People Say
Skintific ISDIN
+ Lightweight and non-greasy texture
Mostly Mentioned Mostly Mentioned
“absorbs instantly — ISDIN Eryfotona Actinica” “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water” “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate” “absorbs instantly — Skintific 5X Ceramide Barrier Moisture Gel”
+ Smoother skin texture
Sometimes Noted Often Mentioned
“skin looks smooth and healthy — ISDIN K-Ox Eyes” “Skin feels intensely hydrated — ISDIN Hyaluronic Concentrate” “I am more on a dehydrated side and this helps me look hydrated and smooth. — ISDIN Flavo-C Serum” “Kulit terasa lebih halus — Skintific AHA BHA PHA LHA Peeling Solution”
+ Calms redness and irritation
Mostly Mentioned Not noted
“calm my acne instantly — Skintific MUGWORT” “redness berkurang — Skintific 5X Ceramide Barrier Moisture Gel” “good for acne prone — Skintific MATE FIT”
+ No white cast
Often Mentioned Sometimes Noted
“invisible, no white cast — Skintific All Day Light Sunscreen Mist” “no white cast — Skintific MATE FIT” “doesn't leave you white as a ghost — ISDIN Fusion Water”
+ Gentle on sensitive skin
Not noted Often Mentioned
“Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture” “no excessive exfoliation — ISDIN Retinal Intense Serum” “doesn't sting eyes — ISDIN Eryfotona Actinica”
+ Brightening and radiance
Sometimes Noted Sometimes Noted
“Tampak lebih cerah — Skintific AHA BHA PHA LHA Peeling Solution” “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum” “skin looks immediately luminous — ISDIN K-Ox Eyes”
– Scent and fragrance dislike
Often Mentioned Often Mentioned
“scent is actually quite strong — Skintific All Day Light Sunscreen Mist” “Bau jamu/rempah — Skintific AHA BHA PHA LHA Peeling Solution” “smell is overpowering — ISDIN Eryfotona Actinica” “lingering headache inducing effect — ISDIN K-Ox Eyes”
– High price point
Not noted Often Mentioned
“very expensive — ISDIN Eryfotona Actinica”
– Strong tingling sensation and irritation
Sometimes Noted Rarely Noted
“mild redness or irritation — ISDIN K-Ox Eyes” “I think the serum is too strong for my face as it has burned and left very rough and a peeling face. — ISDIN Flavo-C Serum” “slight peeling — ISDIN Retinal Intense Serum” “Panas banget di kulit — Skintific AHA BHA PHA LHA Peeling Solution”
Questions and answers
Skintific or ISDIN: which is better?
Both brands have their strengths, as ISDIN is well-regarded for its lightweight and gentle sunscreens while Skintific offers fragrance-free options that reviewers note help calm redness and irritation. Topical hyaluronic acid , featured in ISDIN products, helps improve skin quality and signs of aging.
Dermatologic Therapy, 2022
What is the difference between Skintific and ISDIN?
Skintific is a newer brand founded in 2021 by Guangzhou Feimei Network Technology Co., Ltd., while ISDIN was founded in 1975 in Spain and is owned by Puig. For the products on this page, Skintific lists no fragrance in any of its products, whereas ISDIN includes fragrance in 5 of its 8 products.
Skintific or ISDIN: which moisturizer is better?
ISDIN offers better moisturizer options on this page, such as Hyaluronic Concentrate which Lovi rates as High for sensitive skin. Meanwhile, Skintific features moisturizers like 5X Ceramide Barrier Moisture Gel, which is rated High for dry and dry sensitive skin.
Dermatologic Therapy, 2022
Which is more affordable, Skintific or ISDIN?
Skintific is more affordable, whereas ISDIN is a high price point option.
Which causes fewer breakouts, Skintific or ISDIN?
Both brands offer products that are suitable for breakout-prone skin, with Skintific's All Day Light Sunscreen Mist reaching a High fit level for acne-prone skin and ISDIN featuring options like Eryfotona Actinica that also achieve a High fit level. Topical treatments containing ingredients like hyaluronic acid may help maintain hydration while managing blemishes without clogging pores.
Dermatologic Therapy, 2022
Which brand has more fragrance-free products, Skintific or ISDIN?
Skintific has more fragrance-free products, as every product on its page lists no fragrance in its ingredients. In contrast, only 3 of 8 ISDIN products on this page are fragrance-free.
Which brand was founded earlier, Skintific or ISDIN?
ISDIN was founded earlier in 1975 in Spain, whereas Skintific was founded more recently in 2021.
Which brand is better for calming redness and irritation?
Skintific does better for calming redness and irritation. According to review themes, Skintific excels in calming redness and irritation.
Skintific or ISDIN: which sunscreen is better?
ISDIN offers sunscreens like Eryfotona Actinica that achieve a Superior Lovi fit level for mature and sensitive skin, whereas Skintific products on this page list no fragrance. Both brands provide options that help protect the skin with lightweight textures.
4 more questions
Research behind their key ingredients
Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage
Antioxidants · Drug Delivery, 2017 Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence
Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022 Topical use of dexpanthenol in skin disorders
Panthenol · American Journal of Clinical Dermatology, 2002 Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020 Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing
Bakuchiol · The British Journal of Dermatology, 2019
49 more studies
Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract
Centella asiatica extract · Indian Journal of Pharmaceutical Sciences, 2016 Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
Centella asiatica extract · Pharmaceutics, 2024 Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin
Ceramide · Scientific Reports, 2022 Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial
Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018 Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin
Ceramide np, Ceramide eop · International Journal of Dermatology, 2008 Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation
Ascorbic acid · Journal of Cosmetic Dermatology, 2020 The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021 A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Panthenol · The Journal of Dermatological Treatment, 2017 A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population
Salicylic acid · BioMed Research International, 2020 Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
Glycolic acid · Journal of Cosmetic Dermatology, 2019 Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation
Tocopheryl acetate · Urologia Internationalis, 2019 Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Niacinamide · Scientific Reports, 2024 High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin
Witch hazel extract · Phytochemistry, 2001 Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial
Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020 The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019 Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy
Centella asiatica extract · Molecules, 2023 The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro
Bifida ferment filtrate, Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023 Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study
Salicylic acid · Journal of Cosmetic Dermatology, 2024 Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach
Zinc oxide · Journal of Controlled Release, 2025 A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid
Ceramide np · Skin Pharmacology and Physiology, 2022 Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications
Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015 A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide
Salicylic acid · Journal of Drugs in Dermatology, 2023 Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial
Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020 Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial
Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022 In vivo and in vitro evaluation of octyl methoxycinnamate liposomes
Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013 Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987 Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters
Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019 Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid
Lactobionic acid · Journal of Cosmetic Dermatology, 2010 Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence
Zinc oxide · Biomedicines, 2025 Influence of vitamin E acetate on stratum corneum hydration
Tocopheryl acetate · Arzneimittel-Forschung, 1998 Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters
Octocrylene · Antioxidants, 2025 Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Panthenol · Journal of Cosmetic Dermatology, 2025 A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study
Lactobionic acid · Journal of Cosmetic Dermatology, 2019 TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection
Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023 Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study
Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026 Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation
Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023 Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy
Tocopheryl acetate · Scientific Reports, 2025 Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022 Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum
Caprylic capric triglyceride · Life, 2023 Facial disbiosis and UV filters
Ethylhexyl salicylate · Archives of Dermatological Research, 2024 Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial
Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021 The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024 Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial
Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026 Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin
Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025 Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025 Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026 Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking
Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026 Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population
Bakuchiol · Health Science Reports, 2025
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Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
Nadia Kapleva, MS
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
Alexey Shagraev, PhD
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
Aishani Shah, MD
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
Asya Zubkova, MS
Medical Board
Cosmetic chemist, SCS, IFSCC member
Hanna Kurets, MD
Medical Board, Medical Advisor
Dermatology MD
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist