# Simple vs Shiseido

Page: https://lovi.care/skincare/it/compare/simple-vs-shiseido

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Simple and Shiseido are distinct skincare lines originating from the United Kingdom and Japan, respectively. Simple is beloved for its gentle moisturizers, makeup removers, cleansers, and toners that thoughtfully incorporate [niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide) and [glycerin](https://lovi.care/skincare/it/ingredients/glycerin), while the Japanese brand is known for its thoughtful array of moisturizers, cleansers, sunscreens, [serums](https://lovi.care/skincare/it/ingredients/serum), and more, all formulated with nourishing glycerin. The British brand suits acne-prone skin and mature skin best, whereas its counterpart suits mature skin and skin with dark spots best, owing to their targeted formulations. Ultimately, they differ in their heritage and specific ingredient profiles, with the former offering a nurturing approach to daily care through niacinamide and glycerin, and the latter providing targeted hydration and anti-aging benefits.

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

[corp.shiseido.com](https://corp.shiseido.com/en/company/info/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Shiseido) [marketscreener.com](https://www.marketscreener.com/quote/stock/SHISEIDO-COMPANY-LIMITED-6492328/news/Shiseido-Company-Limited-Announces-CEO-Changes-Effective-January-1-2025-47501230/)

This page compares some of the most popular Simple and Shiseido products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg85dba86392).

### Popular Simple vs Shiseido products

#### Simple

- [Micellar Water](https://lovi.care/skincare/it/p/simple/micellar-water/for/mature-skin) — Average fit — [€8.67 at Amazon](https://www.amazon.it/dp/B00X3OQ6N0?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/it/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit
- [Hydrating Light Moisturiser](https://lovi.care/skincare/it/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [€9.90 at Amazon](https://www.amazon.it/dp/B000LQX6XG?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/it/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [€37.56 at Amazon](https://www.amazon.it/dp/B07QFYSBZQ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/it/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [€17.05 at Amazon](https://www.amazon.it/dp/B014G4ZW1M?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/it/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit — [€19.99 at Amazon](https://www.amazon.it/dp/B0787G22XC?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/it/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [€7.99 at Amazon](https://www.amazon.it/dp/B076V2D94Y?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

#### Shiseido

- [Benefiance Wrinkle Smoothing Eye Cream](https://lovi.care/skincare/it/p/shiseido/benefiance-wrinkle-smoothing-eye-cream/for/mature-skin) — High fit — [€59.95 at Amazon](https://www.amazon.it/dp/B0C9RXV1VY?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/it/p/shiseido/ultimune-power-infusing-concentrate/for/sensitive-skin) — Average fit — [€140.71 at Amazon](https://www.amazon.it/dp/B09MKR9HXR?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [VITAL PERFECTION](https://lovi.care/skincare/it/p/shiseido/vital-perfection/for/mature-skin) — Average fit — [€55.99 at Amazon](https://www.amazon.it/dp/B0FFNGPX46?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Clarifying Cleansing Foam](https://lovi.care/skincare/it/p/shiseido/clarifying-cleansing-foam/for/mature-skin) — Average fit — [€39.99 at Amazon](https://www.amazon.it/dp/B0H4NPLD9T?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Essential Energy Hydrating Cream](https://lovi.care/skincare/it/p/shiseido/essential-energy-hydrating-cream/for/mature-skin) — Superior fit — [€44.82 at Amazon](https://www.amazon.it/dp/B09SBSPXTY?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Activating Essence](https://lovi.care/skincare/it/p/shiseido/activating-essence/for/dry-skin) — High fit
- [FUTURE SOLUTION LX](https://lovi.care/skincare/it/p/shiseido/future-solution-lx/for/sensitive-skin) — High fit
- [Bio-Performance Advanced Super Revitalizing Cream](https://lovi.care/skincare/it/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/dry-skin) — Warning fit — [€99.99 at Amazon](https://www.amazon.it/dp/B0H275MK21?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

## People Say

Simple

Shiseido

- Hydration and moisture Mostly Mentioned Mostly Mentioned “Immediate sensation of comfort — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “skin feels plump, soft and nourished, eliminates dryness, bouncy feel — Shiseido VITAL PERFECTION” “Skin feels more hydrated — Shiseido Activating Essence” “banished dryness within days — Simple Replenishing Rich Moisturiser”
- Gentle on sensitive skin Mostly Mentioned Rarely Noted “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water” “The only cleanser that doesn't turn my face red. — Simple Micellar Water” “no artificial perfume — Simple Hydrating Light Moisturiser” “No irritation — Shiseido Essential Energy Hydrating Cream”
- Lightweight and non-greasy Often Mentioned Sometimes Noted “sinks in instantly — Simple Water Boost Hydrating Gel Cream” “absorbs very quickly — Simple Hydrating Light Moisturiser” “absorbs really well — Simple Replenishing Rich Moisturiser” “Airy-soft texture — Shiseido Essential Energy Hydrating Cream”
- Luxurious texture and feel Not noted Mostly Mentioned “silky smooth, rich but non-greasy, absorbs quickly, melts into skin — Shiseido VITAL PERFECTION” “Velvety, rich cream texture — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Velvety texture — Shiseido FUTURE SOLUTION LX”
- Effective cleansing Often Mentioned Rarely Noted “Takes off any makeup residue and makes my face feel refreshed. — Simple Micellar Cleansing Water” “Best morning cleanser — Simple Refreshing Facial Wash” “removes last traces of makeup — Simple Kind to Skin Soothing Facial Toner” “face feels squeaky clean — Shiseido Clarifying Cleansing Foam”
- Affordable value Often Mentioned Not noted “great value for money — Simple Kind to Skin Soothing Facial Toner” “super affordable — Simple Hydrating Light Moisturiser” “Can't beat the price for the quality. — Simple Micellar Water”
- High price point Not noted Mostly Mentioned “Very expensive for the size — Shiseido Benefiance Wrinkle Smoothing Eye Cream”
- Strong fragrance and scent Not noted Often Mentioned “old lady smell — Shiseido Eudermine Revitalizing Essence”
- Not enough moisture Often Mentioned Rarely Noted “Not enough for winter — Shiseido Essential Energy Hydrating Cream” “feels a bit oily — Shiseido Benefiance Wrinkle Smoothing Cream Enriched” “not moisturizing enough — Simple Hydrating Light Moisturiser”

### Simple vs Shiseido routines for dry skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/it/p/simple/refreshing-facial-wash/for/dry-skin) — Low fit — [€37.56 at Amazon](https://www.amazon.it/dp/B07QFYSBZQ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [€15.16 at Amazon](https://www.amazon.it/dp/B08Q6WZ6J1?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/it/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [€17.05 at Amazon](https://www.amazon.it/dp/B014G4ZW1M?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [€37.19 at Amazon](https://www.amazon.it/dp/B00JJZN1HG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Water](https://lovi.care/skincare/it/p/simple/micellar-water/for/dry-skin) — Average fit — [€8.67 at Amazon](https://www.amazon.it/dp/B00X3OQ6N0?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [SKIN1004 Madagascar Centella Poremizing Fresh Ampoule](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-poremizing-fresh-ampoule/for/dry-skin) — Superior fit — [€16.60 at Amazon](https://www.amazon.it/dp/B0B1JRGGLF?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/it/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [€31.93 at Amazon](https://www.amazon.it/dp/B0BLXHYKTX?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Clarifying Cleansing Foam](https://lovi.care/skincare/it/p/shiseido/clarifying-cleansing-foam/for/dry-skin) — Caution fit — [€39.99 at Amazon](https://www.amazon.it/dp/B0H4NPLD9T?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [€15.16 at Amazon](https://www.amazon.it/dp/B08Q6WZ6J1?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/it/p/shiseido/essential-energy-hydrating-cream/for/dry-skin) — High fit — [€44.82 at Amazon](https://www.amazon.it/dp/B09SBSPXTY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [€37.19 at Amazon](https://www.amazon.it/dp/B00JJZN1HG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/it/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€15.90 at Amazon](https://www.amazon.it/dp/B084Q16G8D?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/it/p/shiseido/ultimune-power-infusing-concentrate/for/dry-skin) — Low fit — [€140.71 at Amazon](https://www.amazon.it/dp/B09MKR9HXR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/it/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [€31.93 at Amazon](https://www.amazon.it/dp/B0BLXHYKTX?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 99% fit](https://lovi.care/skincare/it/skin/dry-skin)

### Simple vs Shiseido routines for oily skin

#### Shiseido-focused routine

- Cleanser: [Deep Cleansing Foam](https://lovi.care/skincare/it/p/shiseido/deep-cleansing-foam/for/oily-skin) — High fit — [€49.95 at Amazon](https://www.amazon.it/dp/B0HD8DFZ9M?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/it/p/shiseido/essential-energy-hydrating-cream/for/oily-skin) — Average fit — [€44.82 at Amazon](https://www.amazon.it/dp/B09SBSPXTY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/it/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€19.50 at Amazon](https://www.amazon.it/dp/B09SN5B88W?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/it/p/shiseido/ultimune-power-infusing-concentrate/for/oily-skin) — Average fit — [€140.71 at Amazon](https://www.amazon.it/dp/B09MKR9HXR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/it/p/simple/refreshing-facial-wash/for/oily-skin) — Average fit — [€37.56 at Amazon](https://www.amazon.it/dp/B07QFYSBZQ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/it/p/simple/replenishing-rich-moisturiser/for/oily-skin) — Average fit — [€17.05 at Amazon](https://www.amazon.it/dp/B014G4ZW1M?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Water](https://lovi.care/skincare/it/p/simple/micellar-water/for/oily-skin) — Average fit — [€8.67 at Amazon](https://www.amazon.it/dp/B00X3OQ6N0?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/it/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€19.50 at Amazon](https://www.amazon.it/dp/B09SN5B88W?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [L'Oreal Paris Revitalift 12% Vitamin C + E + Salicylic Serum](https://lovi.care/skincare/it/p/l-oreal-paris/revitalift-12-vitamin-c-e-salicylic-serum/for/oily-skin) — Superior fit — [€14.21 at Amazon](https://www.amazon.it/dp/B0BKLWC84G?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/it/skin/oily-skin)

### Simple vs Shiseido routines for combination skin

#### Shiseido-focused routine

- Cleanser: [Deep Cleansing Foam](https://lovi.care/skincare/it/p/shiseido/deep-cleansing-foam/for/combination-skin) — High fit — [€49.95 at Amazon](https://www.amazon.it/dp/B0HD8DFZ9M?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/it/p/shiseido/essential-energy-hydrating-cream/for/combination-skin) — Average fit — [€44.82 at Amazon](https://www.amazon.it/dp/B09SBSPXTY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/it/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€17.15 at Amazon](https://www.amazon.it/dp/B09V7Z4TJG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/it/p/shiseido/ultimune-power-infusing-concentrate/for/combination-skin) — Average fit — [€140.71 at Amazon](https://www.amazon.it/dp/B09MKR9HXR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/it/p/simple/refreshing-facial-wash/for/combination-skin) — Average fit — [€37.56 at Amazon](https://www.amazon.it/dp/B07QFYSBZQ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/it/p/simple/replenishing-rich-moisturiser/for/combination-skin) — Average fit — [€17.05 at Amazon](https://www.amazon.it/dp/B014G4ZW1M?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Water](https://lovi.care/skincare/it/p/simple/micellar-water/for/combination-skin) — Average fit — [€8.67 at Amazon](https://www.amazon.it/dp/B00X3OQ6N0?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/it/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€17.15 at Amazon](https://www.amazon.it/dp/B09V7Z4TJG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [NEOGEN Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — [€37.99 at Amazon](https://www.amazon.it/dp/B0B8MVX1PS?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/it/skin/combination-skin)

## Questions and answers

### Simple or Shiseido: which is better?

Simple is better for value-friendly pricing and sensitive skin, while Shiseido is better for luxurious textures and deep hydration. [Niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide) helps control skin aging and pigmentation, and [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) supports skin quality and signs of aging.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What is the difference between Simple and Shiseido?

Simple offers affordable value and is gentle on sensitive skin, while Shiseido provides deep hydration and luxurious textures. Niacinamide helps reduce pigmentation, and hyaluronic acid helps improve skin quality and signs of aging.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Simple or Shiseido for dry skin?

For dry skin, both Simple and Shiseido provide an equal High routine fit level on this page. Shiseido features [glycerin](https://lovi.care/skincare/it/ingredients/glycerin) and hyaluronic acid, where topical hyaluronic acid helps improve skin quality and signs of aging. Simple features niacinamide and glycerin, and niacinamide may help reduce cutaneous pigmentation.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Simple or Shiseido: which cleanser is better?

Simple features effective cleansing, while Shiseido offers deep-cleansing and efficient cleansers with luxurious textures. Simple is more affordable, whereas Shiseido products often come with a high price point and strong fragrance.

### Which is more affordable, Simple or Shiseido?

Simple is more affordable, as reviewers on this page mostly mention its affordable value and high price point for Shiseido.

### Simple or Shiseido: which brand is better for mature skin?

Both Simple and Shiseido provide High routine fit levels for mature skin on the products on this page. Shiseido features formulations that may help with firming and line-reducing benefits, whereas Simple offers value-friendly, lightweight moisturizers.

### Simple or Shiseido: which products contain fragrance?

Shiseido includes products with fragrance, as 15 of 20 Shiseido products on this page list fragrance in their ingredients. In contrast, every product from Simple on this page lists no fragrance.

### Simple or Shiseido: which brand offers better hydration?

Shiseido does better for hydration and moisture according to the review themes on this page. Topical hyaluronic acid, a key ingredient across Shiseido products, helps improve skin quality and signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Simple or Shiseido for oily skin?

Both Simple and Shiseido offer a High routine fit for oily skin on the products on this page. Shiseido features glycerin and hyaluronic acid across its products, while Simple includes niacinamide, which may help regulate oil production.

[Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Simple or Shiseido: which moisturizer is better?

Simple features value-friendly moisturizers that are mostly mentioned by reviewers as lightweight, while Shiseido provides moisturizers known for deep hydration and luxurious textures. Topical hyaluronic acid, a key ingredient found across Shiseido's products on this page, helps improve skin quality and signs of skin aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Simple or Shiseido for sensitive skin?

Simple is better for sensitive skin because the products on this page are rated gentle and sensitive-skin-friendly and list no fragrance, whereas Shiseido features many fragranced formulas.

### Simple or Shiseido for acne-prone skin?

Both Simple and Shiseido provide high routine fit for acne-prone skin on this page. Niacinamide in Simple products may help control skin issues, while Shiseido offers specialized moisturizers and cleansers that help manage acne-prone skin effectively.

[Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/) [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/16778793/) Squalane · The Journal of Investigative Dermatology, 2006
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Psychophysical study of the effects of topical application of menthol in healthy volunteers](https://pubmed.ncbi.nlm.nih.gov/16527405/) Menthol · Pain, 2006
- [Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/25607790/) Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014
- [Ethanol extracts of Sanguisorba officinalis L. suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells](https://pubmed.ncbi.nlm.nih.gov/26655409/) Sanguisorba officinalis root extract · Phytomedicine, 2015
- [Skin barrier disruption by sodium lauryl sulfate-exposure alters the expressions of involucrin, transglutaminase 1, profilaggrin, and kallikreins during the repair phase in human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/18007579/) Sodium lauryl sulfate · The Journal of Investigative Dermatology, 2008
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling](https://pubmed.ncbi.nlm.nih.gov/16890388/) Panax ginseng root extract · Journal of Ethnopharmacology, 2007
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia](https://pubmed.ncbi.nlm.nih.gov/23963768/) Menthol · European Journal of Pain, 2014
- [Design, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies](https://pubmed.ncbi.nlm.nih.gov/30442066/) Lauric acid · Drug Development and Industrial Pharmacy, 2019
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract](https://pubmed.ncbi.nlm.nih.gov/26203268/) Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf extract · Phytochemistry, 2001
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015
- [Changes in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy](https://pubmed.ncbi.nlm.nih.gov/33804924/) Sodium lauryl sulfate · Pharmaceutics, 2021
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [A novel model of inflammatory pain in human skin involving topical application of sodium lauryl sulfate](https://pubmed.ncbi.nlm.nih.gov/20358390/) Sodium lauryl sulfate · Inflammation Research, 2010
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry](https://pubmed.ncbi.nlm.nih.gov/16013388/) Myristic acid · Journal of Food Protection, 2005
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 2-o-ethyl ascorbic acid · Polymers, 2023
- [Synergistic approach for acne vulgaris treatment using glycerosomes loaded with lincomycin and lauric acid: Formulation, in silico, in vitro, LC-MS/MS skin deposition assay and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/37805147/) Lauric acid · International Journal of Pharmaceutics, 2023
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Anatomical site differences of sodium lauryl sulfate-induced irritation: randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/30637727/) Sodium lauryl sulfate · The British Journal of Dermatology, 2019
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling](https://pubmed.ncbi.nlm.nih.gov/40345503/) Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/36431167/) Theanine · Journal of Clinical Medicine, 2022
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 2-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Transdermal Delivery of Baicalin Based on Bio-Vesicles and Its Efficacy in Antiaging of the Skin](https://pubmed.ncbi.nlm.nih.gov/39946269/) Scutellaria baicalensis root extract · Journal of Cosmetic Dermatology, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes](https://pubmed.ncbi.nlm.nih.gov/28447741/) Artemisia princeps leaf extract · Molecular Medicine Reports, 2017
- [Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability](https://pubmed.ncbi.nlm.nih.gov/39985147/) 2-o-ethyl ascorbic acid · Journal of Liposome Research, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 2-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Potassium 4-Methoxysalicylate (4MSK) Exerts a Skin Lightening Effect by Acting on Melanocytes and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/40071590/) Potassium methoxysalicylate · Journal of Cosmetic Dermatology, 2025
- [New Chalcone-Derived Molecule for the Topical Regulation of Hyperpigmentation and Skin Aging](https://pubmed.ncbi.nlm.nih.gov/39598529/) Angelica keiskei leaf extract · Pharmaceutics, 2024
- [Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin](https://pubmed.ncbi.nlm.nih.gov/39138602/) Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate, Octocrylene · Archives of Dermatological Research, 2024
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Saccharide isomerate · Lasers in Medical Science, 2025
- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026
- [Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/37194909/) Uji green tea extract · Journal of Cosmetic Dermatology, 2023
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate · Journal of Drugs in Dermatology, 2025

## The brands

- British skincare: [Simple](https://lovi.care/skincare/it/brands/simple)
- Japanese skincare: [Shiseido](https://lovi.care/skincare/it/brands/shiseido)

## More comparisons

- [SKIN1004 vs Simple](https://lovi.care/skincare/it/compare/skin1004-vs-simple)
- [SKIN1004 vs Shiseido](https://lovi.care/skincare/it/compare/skin1004-vs-shiseido)
- [Anua vs Simple](https://lovi.care/skincare/it/compare/anua-vs-simple)
- [Anua vs Shiseido](https://lovi.care/skincare/it/compare/anua-vs-shiseido)
- [Medicube vs Simple](https://lovi.care/skincare/it/compare/medicube-vs-simple)
- [Medicube vs Shiseido](https://lovi.care/skincare/it/compare/medicube-vs-shiseido)
- [The Ordinary vs Simple](https://lovi.care/skincare/it/compare/the-ordinary-vs-simple)
- [The Ordinary vs Shiseido](https://lovi.care/skincare/it/compare/the-ordinary-vs-shiseido)
- [Beauty of Joseon vs Simple](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-simple)
- [Beauty of Joseon vs Shiseido](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-shiseido)
- [COSRX vs Simple](https://lovi.care/skincare/it/compare/cosrx-vs-simple)
- [COSRX vs Shiseido](https://lovi.care/skincare/it/compare/cosrx-vs-shiseido)
- [CeraVe vs Simple](https://lovi.care/skincare/it/compare/cerave-vs-simple)
- [CeraVe vs Shiseido](https://lovi.care/skincare/it/compare/cerave-vs-shiseido)
- [La Roche-Posay vs Simple](https://lovi.care/skincare/it/compare/la-roche-posay-vs-simple)
- [La Roche-Posay vs Shiseido](https://lovi.care/skincare/it/compare/la-roche-posay-vs-shiseido)
- [Dr. Althea vs Simple](https://lovi.care/skincare/it/compare/dr-althea-vs-simple)
- [Dr. Althea vs Shiseido](https://lovi.care/skincare/it/compare/dr-althea-vs-shiseido)
- [Some By Mi vs Simple](https://lovi.care/skincare/it/compare/some-by-mi-vs-simple)
- [Some By Mi vs Shiseido](https://lovi.care/skincare/it/compare/some-by-mi-vs-shiseido)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/simple-vs-shiseido
- United Kingdom: https://lovi.care/skincare/uk/compare/simple-vs-shiseido
- Ireland: https://lovi.care/skincare/ie/compare/simple-vs-shiseido
- Germany: https://lovi.care/skincare/de/compare/simple-vs-shiseido
- France: https://lovi.care/skincare/fr/compare/simple-vs-shiseido
- Italy: https://lovi.care/skincare/it/compare/simple-vs-shiseido (this page)
- Netherlands: https://lovi.care/skincare/nl/compare/simple-vs-shiseido
- Spain: https://lovi.care/skincare/es/compare/simple-vs-shiseido
- Canada: https://lovi.care/skincare/ca/compare/simple-vs-shiseido
- Australia: https://lovi.care/skincare/au/compare/simple-vs-shiseido
- Singapore: https://lovi.care/skincare/sg/compare/simple-vs-shiseido
- Saudi Arabia: https://lovi.care/skincare/sa/compare/simple-vs-shiseido
- United Arab Emirates: https://lovi.care/skincare/ae/compare/simple-vs-shiseido