# Simple vs Natura Bissé

Page: https://lovi.care/skincare/it/compare/simple-vs-natura-bisse

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Simple and Natura Bissé are distinct skincare brands founded in Britain and Spain respectively, offering tailored approaches to daily care. Simple is a British brand known for its gentle moisturizers, makeup removers, cleansers, and toners featuring [niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide) and [glycerin](https://lovi.care/skincare/it/ingredients/glycerin), which suit acne-prone skin and mature skin best. Meanwhile, the Spanish brand is loved for its luxurious moisturizers and advanced formulas that cater ideally to mature, dry, and sensitive skin. While both brands restore balance and vitality to the complexion, they differ significantly in their ingredient profiles, product textures, and overall positioning.

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

Natura Bissé is a Spanish skincare brand founded in 1979 and owned by Natura Bissé International, S.A..

[naturabisse.com](https://www.naturabisse.com/int/en/our-story.html) [tracxn.com](https://tracxn.com/d/accelerator-incubator/ushopal/__yjGH7DKhQGNWnINKarEuFce6tilrPzGJv0PnASFLfpg)

This page compares some of the most popular Simple and Natura Bissé products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgea284af400).

### Popular Simple vs Natura Bissé products

#### Natura Bissé

- [Diamond Extreme](https://lovi.care/skincare/it/p/natura-bisse/diamond-extreme/for/mature-skin) — Superior fit — [€266.80 at Amazon](https://www.amazon.it/dp/B0BKLRMKZV?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

#### Simple

- [Micellar Water](https://lovi.care/skincare/it/p/simple/micellar-water/for/mature-skin) — Average fit — [€8.67 at Amazon](https://www.amazon.it/dp/B00X3OQ6N0?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/it/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit
- [Hydrating Light Moisturiser](https://lovi.care/skincare/it/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [€9.90 at Amazon](https://www.amazon.it/dp/B000LQX6XG?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/it/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [€37.56 at Amazon](https://www.amazon.it/dp/B07QFYSBZQ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/it/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [€17.05 at Amazon](https://www.amazon.it/dp/B014G4ZW1M?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/it/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit — [€19.99 at Amazon](https://www.amazon.it/dp/B0787G22XC?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/it/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [€7.99 at Amazon](https://www.amazon.it/dp/B076V2D94Y?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Simple or Natura Bissé: which is better?

Simple offers budget-friendly, fragrance-free products on this page that Lovi rates as high for sensitive skin, while Natura Bissé provides a luxury [moisturizing cream](https://lovi.care/skincare/it/ingredients/moisturizing-cream) with fragrance that Lovi rates as superior for mature skin. [Glycerin](https://lovi.care/skincare/it/ingredients/glycerin) helps provide hydration across the products.

[Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What is the difference between Simple and Natura Bissé?

Simple features fragrance-free products on the page that include key ingredients like [niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide) and glycerin, and Lovi rates the brand best for acne-prone skin, mature skin, and skin with dark spots. In contrast, Natura Bissé features a single luxury moisturizer on the page that contains fragrance, with Diamond Extreme rated by Lovi as a Superior fit for mature skin.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Simple or Natura Bissé: which moisturizer is better?

Simple offers lightweight, value-friendly moisturizers with fragrance-free formulas, while Natura Bissé provides the rich Diamond Extreme cream which contains fragrance. Lovi rates Simple moisturizers mostly at an Average fit across skin types, whereas Natura Bissé's Diamond Extreme achieves a Superior fit for mature skin and High fits for dry and dry sensitive skin.

### Which is more affordable, Simple or Natura Bissé?

Simple offers more affordable options, with reviewers frequently mentioning its lightweight and value-friendly moisturizers. Natura Bissé features higher-end pricing, represented by a luxury moisturizer on this page.

### Which causes fewer breakouts, Simple or Natura Bissé?

Simple features gentle, sensitive-skin-friendly makeup removers, but reviewers note that it sometimes causes breakouts or irritations, while Natura Bissé has no specific consumer reviews about breakouts on this page.

### Which brand has been around longer, Simple or Natura Bissé?

Simple has been around longer, having been founded in the United Kingdom in 1960 compared to Natura Bissé, which was founded in Spain in 1979.

### Do any products from Simple contain fragrance compared to Natura Bissé?

Simple products are fragrance-free, whereas Natura Bissé includes fragrance in its products on this page.

### Which brand offers more product options on this page?

Simple offers more product options on this page with seven items listed, whereas Natura Bissé features only one product. Reviewers note that the products on this page from Simple are mostly lightweight, value-friendly moisturizers and gentle, sensitive-skin-friendly makeup removers.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum leaf extract flower · Genes, 2020
- [Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells](https://pubmed.ncbi.nlm.nih.gov/23093820/) Leontopodium alpinum leaf extract flower · Mediators of Inflammation, 2012
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function](https://pubmed.ncbi.nlm.nih.gov/35409270/) Rosamarinus officinalis leaf extract rosemary leaf extract · International Journal of Molecular Sciences, 2022
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Formulation and evaluation of exotic fat based cosmeceuticals for skin repair](https://pubmed.ncbi.nlm.nih.gov/20046792/) Mangifera indica seed butter · Indian Journal of Pharmaceutical Sciences, 2008
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- British skincare: [Simple](https://lovi.care/skincare/it/brands/simple)
- Spanish skincare: [Natura Bissé](https://lovi.care/skincare/it/brands/natura-bisse)

## More comparisons

- [SKIN1004 vs Simple](https://lovi.care/skincare/it/compare/skin1004-vs-simple)
- [SKIN1004 vs Natura Bissé](https://lovi.care/skincare/it/compare/skin1004-vs-natura-bisse)
- [Anua vs Simple](https://lovi.care/skincare/it/compare/anua-vs-simple)
- [Anua vs Natura Bissé](https://lovi.care/skincare/it/compare/anua-vs-natura-bisse)
- [Medicube vs Simple](https://lovi.care/skincare/it/compare/medicube-vs-simple)
- [Medicube vs Natura Bissé](https://lovi.care/skincare/it/compare/medicube-vs-natura-bisse)
- [The Ordinary vs Simple](https://lovi.care/skincare/it/compare/the-ordinary-vs-simple)
- [The Ordinary vs Natura Bissé](https://lovi.care/skincare/it/compare/the-ordinary-vs-natura-bisse)
- [Beauty of Joseon vs Simple](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-simple)
- [Beauty of Joseon vs Natura Bissé](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-natura-bisse)
- [COSRX vs Simple](https://lovi.care/skincare/it/compare/cosrx-vs-simple)
- [COSRX vs Natura Bissé](https://lovi.care/skincare/it/compare/cosrx-vs-natura-bisse)
- [CeraVe vs Simple](https://lovi.care/skincare/it/compare/cerave-vs-simple)
- [CeraVe vs Natura Bissé](https://lovi.care/skincare/it/compare/cerave-vs-natura-bisse)
- [La Roche-Posay vs Simple](https://lovi.care/skincare/it/compare/la-roche-posay-vs-simple)
- [La Roche-Posay vs Natura Bissé](https://lovi.care/skincare/it/compare/la-roche-posay-vs-natura-bisse)
- [Dr. Althea vs Simple](https://lovi.care/skincare/it/compare/dr-althea-vs-simple)
- [Dr. Althea vs Natura Bissé](https://lovi.care/skincare/it/compare/dr-althea-vs-natura-bisse)
- [Some By Mi vs Simple](https://lovi.care/skincare/it/compare/some-by-mi-vs-simple)
- [Some By Mi vs Natura Bissé](https://lovi.care/skincare/it/compare/some-by-mi-vs-natura-bisse)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/simple-vs-natura-bisse
- United Kingdom: https://lovi.care/skincare/uk/compare/simple-vs-natura-bisse
- Ireland: https://lovi.care/skincare/ie/compare/simple-vs-natura-bisse
- Germany: https://lovi.care/skincare/de/compare/simple-vs-natura-bisse
- France: https://lovi.care/skincare/fr/compare/simple-vs-natura-bisse
- Italy: https://lovi.care/skincare/it/compare/simple-vs-natura-bisse (this page)
- Netherlands: https://lovi.care/skincare/nl/compare/simple-vs-natura-bisse
- Spain: https://lovi.care/skincare/es/compare/simple-vs-natura-bisse
- Canada: https://lovi.care/skincare/ca/compare/simple-vs-natura-bisse
- Australia: https://lovi.care/skincare/au/compare/simple-vs-natura-bisse
- Singapore: https://lovi.care/skincare/sg/compare/simple-vs-natura-bisse
- Saudi Arabia: https://lovi.care/skincare/sa/compare/simple-vs-natura-bisse
- United Arab Emirates: https://lovi.care/skincare/ae/compare/simple-vs-natura-bisse