# Shiseido vs ISDIN

Page: https://lovi.care/skincare/it/compare/shiseido-vs-isdin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Shiseido and ISDIN are distinguished skincare brands that offer thoughtful selections of moisturizers, cleansers, sunscreens, and [serums](https://lovi.care/skincare/it/ingredients/serum). The Japanese brand is beloved for nourishing [glycerin](https://lovi.care/skincare/it/ingredients/glycerin) formulations that suit mature skin and skin with dark spots best, whereas the Spanish brand provides elegant, balanced products that suit dry skin and sensitive skin best. While both deliver reliable daily support, they differ in their heritage and targeted ingredients, with Shiseido focusing on stratum corneum hydration and ISDIN emphasizing gentle daily comfort.

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

[corp.shiseido.com](https://corp.shiseido.com/en/company/info/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Shiseido) [marketscreener.com](https://www.marketscreener.com/quote/stock/SHISEIDO-COMPANY-LIMITED-6492328/news/Shiseido-Company-Limited-Announces-CEO-Changes-Effective-January-1-2025-47501230/)

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

This page compares some of the most popular Shiseido and ISDIN products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg6b4e58f55e).

### Popular Shiseido vs ISDIN products

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/it/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [€75.20 at Amazon](https://www.amazon.it/dp/B0H6FCL372?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/it/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [€23.99 at Amazon](https://www.amazon.it/dp/B00Z72U6JQ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/it/p/isdin/k-ox-eyes/for/dry-skin) — High fit — [€41.50 at Amazon](https://www.amazon.it/dp/B01BMLQ4JQ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Concentrate](https://lovi.care/skincare/it/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/it/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/it/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [€48.88 at Amazon](https://www.amazon.it/dp/B01BMLQ086?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/it/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/it/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [€69.00 at Amazon](https://www.amazon.it/dp/B0BD9DK6SC?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

#### Shiseido

- [Benefiance Wrinkle Smoothing Eye Cream](https://lovi.care/skincare/it/p/shiseido/benefiance-wrinkle-smoothing-eye-cream/for/mature-skin) — High fit — [€59.95 at Amazon](https://www.amazon.it/dp/B0C9RXV1VY?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/it/p/shiseido/ultimune-power-infusing-concentrate/for/sensitive-skin) — Average fit — [€140.71 at Amazon](https://www.amazon.it/dp/B09MKR9HXR?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [VITAL PERFECTION](https://lovi.care/skincare/it/p/shiseido/vital-perfection/for/mature-skin) — Average fit — [€55.99 at Amazon](https://www.amazon.it/dp/B0FFNGPX46?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Clarifying Cleansing Foam](https://lovi.care/skincare/it/p/shiseido/clarifying-cleansing-foam/for/mature-skin) — Average fit — [€39.99 at Amazon](https://www.amazon.it/dp/B0H4NPLD9T?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Essential Energy Hydrating Cream](https://lovi.care/skincare/it/p/shiseido/essential-energy-hydrating-cream/for/mature-skin) — Superior fit — [€44.82 at Amazon](https://www.amazon.it/dp/B09SBSPXTY?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Activating Essence](https://lovi.care/skincare/it/p/shiseido/activating-essence/for/dry-skin) — High fit
- [FUTURE SOLUTION LX](https://lovi.care/skincare/it/p/shiseido/future-solution-lx/for/sensitive-skin) — High fit
- [Bio-Performance Advanced Super Revitalizing Cream](https://lovi.care/skincare/it/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/dry-skin) — Warning fit — [€99.99 at Amazon](https://www.amazon.it/dp/B0H275MK21?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

## People Say

Shiseido

ISDIN

- Luxurious and lightweight textures Mostly Mentioned Mostly Mentioned “silky smooth, rich but non-greasy, absorbs quickly, melts into skin — Shiseido VITAL PERFECTION” “Airy-soft texture — Shiseido Essential Energy Hydrating Cream” “absorbs instantly — ISDIN Eryfotona Actinica” “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- Deep hydration and moisture Mostly Mentioned Sometimes Noted “Immediate sensation of comfort — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Lightweight, silky, non-sticky, sinks in instantly. — Shiseido Ultimune Power Infusing Concentrate” “skin feels plump, soft and nourished, eliminates dryness, bouncy feel — Shiseido VITAL PERFECTION” “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- Anti-aging and skin smoothing Often Mentioned Often Mentioned “Smoothed out crow's feet — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Skin looks brighter, more radiant, and "glowy." — Shiseido Ultimune Power Infusing Concentrate” “skin looks smooth and healthy — ISDIN K-Ox Eyes” “helps reduce swelling in the area of my under-eye bags — ISDIN K-Ox Eyes”
- Brightening and radiant glow Often Mentioned Often Mentioned “faded pimple marks — Shiseido White Lucent Brightening Gel Cream” “Eyes look more awake — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum” “fades dark spots — ISDIN Eryfotona Actinica”
- Sensitive skin friendly Not noted Often Mentioned “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture” “no excessive exfoliation — ISDIN Retinal Intense Serum” “doesn't sting eyes — ISDIN Eryfotona Actinica”
- Makeup compatibility Rarely Noted Often Mentioned “acts like a primer — ISDIN Eryfotona Actinica” “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water” “Great under makeup — ISDIN Hyaluronic Concentrate” “Great base for makeup — Shiseido Essential Energy Hydrating Cream”
- High price point Mostly Mentioned Often Mentioned “very expensive — ISDIN Eryfotona Actinica” “My only wish is that ISDIN would make this product in a bigger size bottle. — ISDIN Fusion Water” “high cost — ISDIN K-Ox Eyes” “Very expensive for the size — Shiseido Benefiance Wrinkle Smoothing Eye Cream”
- Strong fragrance and scent concerns Often Mentioned Often Mentioned “smell is overpowering — ISDIN Eryfotona Actinica” “lingering headache inducing effect — ISDIN K-Ox Eyes” “it does have a smell it does have fragrance. and it's not necessarily a pleasant one. — ISDIN Fusion Water” “old lady smell — Shiseido Eudermine Revitalizing Essence”
- Skin irritation and reactions Sometimes Noted Sometimes Noted “Caused some irritation — Shiseido Bio-Performance Advanced Super Revitalizing Cream” “Caused burning and redness — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “this did make my eyes water water in the sun. — ISDIN Fusion Water” “mild redness or irritation — ISDIN K-Ox Eyes”

### Shiseido vs ISDIN routines for dry skin

#### ISDIN-focused routine

- Cleanser: [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [€9.19 at Amazon](https://www.amazon.it/dp/B07C5R51Q9?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [€15.16 at Amazon](https://www.amazon.it/dp/B08Q6WZ6J1?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Elizabeth Arden Advanced Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/it/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/dry-skin) — Superior fit — [€53.50 at Amazon](https://www.amazon.it/dp/B09D2F2YF6?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Fusion Water](https://lovi.care/skincare/it/p/isdin/fusion-water/for/dry-skin) — Superior fit — [€23.99 at Amazon](https://www.amazon.it/dp/B00Z72U6JQ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/it/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€15.90 at Amazon](https://www.amazon.it/dp/B084Q16G8D?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/it/p/isdin/flavo-c-serum/for/dry-skin) — Average fit — [€48.88 at Amazon](https://www.amazon.it/dp/B01BMLQ086?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/it/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [€31.93 at Amazon](https://www.amazon.it/dp/B0BLXHYKTX?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Clarifying Cleansing Foam](https://lovi.care/skincare/it/p/shiseido/clarifying-cleansing-foam/for/dry-skin) — Caution fit — [€39.99 at Amazon](https://www.amazon.it/dp/B0H4NPLD9T?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [€15.16 at Amazon](https://www.amazon.it/dp/B08Q6WZ6J1?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/it/p/shiseido/essential-energy-hydrating-cream/for/dry-skin) — High fit — [€44.82 at Amazon](https://www.amazon.it/dp/B09SBSPXTY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [€37.19 at Amazon](https://www.amazon.it/dp/B00JJZN1HG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/it/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€15.90 at Amazon](https://www.amazon.it/dp/B084Q16G8D?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/it/p/shiseido/ultimune-power-infusing-concentrate/for/dry-skin) — Low fit — [€140.71 at Amazon](https://www.amazon.it/dp/B09MKR9HXR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/it/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [€31.93 at Amazon](https://www.amazon.it/dp/B0BLXHYKTX?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 99% fit](https://lovi.care/skincare/it/skin/dry-skin)

### Shiseido vs ISDIN routines for oily skin

#### ISDIN-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€24.75 at Amazon](https://www.amazon.it/dp/B0CRSJ46YD?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — [€18.47 at Amazon](https://www.amazon.it/dp/B01CLTKI4A?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/it/p/isdin/eryfotona-actinica/for/oily-skin) — High fit — [€75.20 at Amazon](https://www.amazon.it/dp/B0H6FCL372?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/it/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€19.50 at Amazon](https://www.amazon.it/dp/B09SN5B88W?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/it/p/isdin/flavo-c-serum/for/oily-skin) — High fit — [€48.88 at Amazon](https://www.amazon.it/dp/B01BMLQ086?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Deep Cleansing Foam](https://lovi.care/skincare/it/p/shiseido/deep-cleansing-foam/for/oily-skin) — High fit — [€49.95 at Amazon](https://www.amazon.it/dp/B0HD8DFZ9M?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/it/p/shiseido/essential-energy-hydrating-cream/for/oily-skin) — Average fit — [€44.82 at Amazon](https://www.amazon.it/dp/B09SBSPXTY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/it/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€19.50 at Amazon](https://www.amazon.it/dp/B09SN5B88W?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/it/p/shiseido/ultimune-power-infusing-concentrate/for/oily-skin) — Average fit — [€140.71 at Amazon](https://www.amazon.it/dp/B09MKR9HXR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/it/skin/oily-skin)

### Shiseido vs ISDIN routines for combination skin

#### ISDIN-focused routine

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — [€13.50 at Amazon](https://www.amazon.it/dp/B07RY6Q6QM?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/it/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — [€18.47 at Amazon](https://www.amazon.it/dp/B01CLTKI4A?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/it/p/isdin/eryfotona-actinica/for/combination-skin) — High fit — [€75.20 at Amazon](https://www.amazon.it/dp/B0H6FCL372?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/it/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€17.15 at Amazon](https://www.amazon.it/dp/B09V7Z4TJG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/it/p/isdin/flavo-c-serum/for/combination-skin) — High fit — [€48.88 at Amazon](https://www.amazon.it/dp/B01BMLQ086?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Deep Cleansing Foam](https://lovi.care/skincare/it/p/shiseido/deep-cleansing-foam/for/combination-skin) — High fit — [€49.95 at Amazon](https://www.amazon.it/dp/B0HD8DFZ9M?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/it/p/shiseido/essential-energy-hydrating-cream/for/combination-skin) — Average fit — [€44.82 at Amazon](https://www.amazon.it/dp/B09SBSPXTY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/it/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€17.15 at Amazon](https://www.amazon.it/dp/B09V7Z4TJG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/it/p/shiseido/ultimune-power-infusing-concentrate/for/combination-skin) — Average fit — [€140.71 at Amazon](https://www.amazon.it/dp/B09MKR9HXR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/it/skin/combination-skin)

## Questions and answers

### Shiseido or ISDIN: which is better?

Both brands are great choices depending on your priorities, as Shiseido stands out for deep hydration and luxurious textures, while ISDIN is recognized for its ultralight, sensitive skin friendly sunscreens. Lovi fit ratings show that ISDIN has superior routine fit for dry skin, while Shiseido also offers high fit for dry skin.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between Shiseido and ISDIN?

Shiseido and ISDIN are both skin care brands, but Shiseido is known for deep hydration and luxurious textures across the products on this page, while ISDIN is recognized for ultralight, makeup-friendly, and sensitive-skin-friendly sunscreens.

### Shiseido or ISDIN for dry skin?

Both Shiseido and ISDIN are great for dry skin, with Lovi fit levels of High and Superior respectively for the products on this page. [Hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) helps provide deep hydration across both brands.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Shiseido or ISDIN: which moisturizer is better?

ISDIN is the better choice for moisturizers because its products on this page achieve a Superior Lovi fit level for dry and sensitive skin compared to Shiseido's High fit.

### Which is more affordable, Shiseido or ISDIN?

Both Shiseido and ISDIN have a high price point according to reviewers on this page.

### Shiseido or ISDIN for fading dark spots?

Both brands help with dark spots, with Shiseido earning a High Lovi fit for products like White Lucent Brightening Gel Cream and ISDIN earning a Superior fit for sunscreens like Eryfotona Actinica. Topical hyaluronic acid, found in the products on this page, helps improve skin quality and signs of skin aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Shiseido or ISDIN: which has better sunscreens for sensitive skin?

ISDIN sunscreens are better for sensitive skin on this page, as ISDIN is noted for being sensitive skin friendly and offers sunscreens with a Superior fit level for sensitive skin, compared to Shiseido's Average fit level.

### Shiseido or ISDIN for oily skin?

For oily skin, Lovi finds that both Shiseido and ISDIN do well with a Superior routine fit. Shiseido features deep-cleansing and efficient cleansers like Deep Cleansing Foam which has a High fit for oily skin, whereas ISDIN is noted for its ultralight sunscreens.

### Shiseido or ISDIN: which sunscreen is better?

ISDIN sunscreen is better, as the products on this page achieve a Superior Lovi fit level for dry and sensitive skin. Hyaluronic acid helps maintain hydration and improves skin quality.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Shiseido or ISDIN for sensitive skin?

Both Shiseido and ISDIN are great for sensitive skin, but ISDIN is noted as more sensitive skin friendly overall. Lovi rates Shiseido's routine for sensitive skin as High and ISDIN's as Superior.

### Shiseido or ISDIN for acne-prone skin?

Both Shiseido and ISDIN are good options for acne-prone skin, with the products on this page offering high or superior routine fit. Shiseido provides options like Essential Energy Hydrating Cream, while ISDIN features sunscreens like Fusion [Water](https://lovi.care/skincare/it/ingredients/water) that help with lightweight protection.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Shiseido or ISDIN for mature skin?

Both brands are great for mature skin, with Lovi giving Shiseido a High fit and ISDIN a Superior fit. Topical hyaluronic acid helps hydrate mature skin and improve signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/16778793/) Squalane · The Journal of Investigative Dermatology, 2006
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Psychophysical study of the effects of topical application of menthol in healthy volunteers](https://pubmed.ncbi.nlm.nih.gov/16527405/) Menthol · Pain, 2006
- [Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/25607790/) Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014
- [Ethanol extracts of Sanguisorba officinalis L. suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells](https://pubmed.ncbi.nlm.nih.gov/26655409/) Sanguisorba officinalis root extract · Phytomedicine, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Skin barrier disruption by sodium lauryl sulfate-exposure alters the expressions of involucrin, transglutaminase 1, profilaggrin, and kallikreins during the repair phase in human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/18007579/) Sodium lauryl sulfate · The Journal of Investigative Dermatology, 2008
- [Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling](https://pubmed.ncbi.nlm.nih.gov/16890388/) Panax ginseng root extract · Journal of Ethnopharmacology, 2007
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia](https://pubmed.ncbi.nlm.nih.gov/23963768/) Menthol · European Journal of Pain, 2014
- [Design, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies](https://pubmed.ncbi.nlm.nih.gov/30442066/) Lauric acid · Drug Development and Industrial Pharmacy, 2019
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract](https://pubmed.ncbi.nlm.nih.gov/26203268/) Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf extract · Phytochemistry, 2001
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Changes in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy](https://pubmed.ncbi.nlm.nih.gov/33804924/) Sodium lauryl sulfate · Pharmaceutics, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [A novel model of inflammatory pain in human skin involving topical application of sodium lauryl sulfate](https://pubmed.ncbi.nlm.nih.gov/20358390/) Sodium lauryl sulfate · Inflammation Research, 2010
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry](https://pubmed.ncbi.nlm.nih.gov/16013388/) Myristic acid · Journal of Food Protection, 2005
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 2-o-ethyl ascorbic acid · Polymers, 2023
- [Synergistic approach for acne vulgaris treatment using glycerosomes loaded with lincomycin and lauric acid: Formulation, in silico, in vitro, LC-MS/MS skin deposition assay and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/37805147/) Lauric acid · International Journal of Pharmaceutics, 2023
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Anatomical site differences of sodium lauryl sulfate-induced irritation: randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/30637727/) Sodium lauryl sulfate · The British Journal of Dermatology, 2019
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling](https://pubmed.ncbi.nlm.nih.gov/40345503/) Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/36431167/) Theanine · Journal of Clinical Medicine, 2022
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 2-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Transdermal Delivery of Baicalin Based on Bio-Vesicles and Its Efficacy in Antiaging of the Skin](https://pubmed.ncbi.nlm.nih.gov/39946269/) Scutellaria baicalensis root extract · Journal of Cosmetic Dermatology, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes](https://pubmed.ncbi.nlm.nih.gov/28447741/) Artemisia princeps leaf extract · Molecular Medicine Reports, 2017
- [Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability](https://pubmed.ncbi.nlm.nih.gov/39985147/) 2-o-ethyl ascorbic acid · Journal of Liposome Research, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 2-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Potassium 4-Methoxysalicylate (4MSK) Exerts a Skin Lightening Effect by Acting on Melanocytes and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/40071590/) Potassium methoxysalicylate · Journal of Cosmetic Dermatology, 2025
- [New Chalcone-Derived Molecule for the Topical Regulation of Hyperpigmentation and Skin Aging](https://pubmed.ncbi.nlm.nih.gov/39598529/) Angelica keiskei leaf extract · Pharmaceutics, 2024
- [Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin](https://pubmed.ncbi.nlm.nih.gov/39138602/) Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026
- [Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/37194909/) Uji green tea extract · Journal of Cosmetic Dermatology, 2023
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025

## The brands

- Japanese skincare: [Shiseido](https://lovi.care/skincare/it/brands/shiseido)
- Spanish skincare: [ISDIN](https://lovi.care/skincare/it/brands/isdin)

## More comparisons

- [SKIN1004 vs Shiseido](https://lovi.care/skincare/it/compare/skin1004-vs-shiseido)
- [SKIN1004 vs ISDIN](https://lovi.care/skincare/it/compare/skin1004-vs-isdin)
- [Anua vs Shiseido](https://lovi.care/skincare/it/compare/anua-vs-shiseido)
- [Anua vs ISDIN](https://lovi.care/skincare/it/compare/anua-vs-isdin)
- [Medicube vs Shiseido](https://lovi.care/skincare/it/compare/medicube-vs-shiseido)
- [Medicube vs ISDIN](https://lovi.care/skincare/it/compare/medicube-vs-isdin)
- [The Ordinary vs Shiseido](https://lovi.care/skincare/it/compare/the-ordinary-vs-shiseido)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/it/compare/the-ordinary-vs-isdin)
- [Beauty of Joseon vs Shiseido](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-shiseido)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-isdin)
- [COSRX vs Shiseido](https://lovi.care/skincare/it/compare/cosrx-vs-shiseido)
- [COSRX vs ISDIN](https://lovi.care/skincare/it/compare/cosrx-vs-isdin)
- [CeraVe vs Shiseido](https://lovi.care/skincare/it/compare/cerave-vs-shiseido)
- [CeraVe vs ISDIN](https://lovi.care/skincare/it/compare/cerave-vs-isdin)
- [La Roche-Posay vs Shiseido](https://lovi.care/skincare/it/compare/la-roche-posay-vs-shiseido)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/it/compare/la-roche-posay-vs-isdin)
- [Dr. Althea vs Shiseido](https://lovi.care/skincare/it/compare/dr-althea-vs-shiseido)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/it/compare/dr-althea-vs-isdin)
- [Some By Mi vs Shiseido](https://lovi.care/skincare/it/compare/some-by-mi-vs-shiseido)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/it/compare/some-by-mi-vs-isdin)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/shiseido-vs-isdin
- United Kingdom: https://lovi.care/skincare/uk/compare/shiseido-vs-isdin
- Ireland: https://lovi.care/skincare/ie/compare/shiseido-vs-isdin
- Germany: https://lovi.care/skincare/de/compare/shiseido-vs-isdin
- France: https://lovi.care/skincare/fr/compare/shiseido-vs-isdin
- Italy: https://lovi.care/skincare/it/compare/shiseido-vs-isdin (this page)
- Netherlands: https://lovi.care/skincare/nl/compare/shiseido-vs-isdin
- Spain: https://lovi.care/skincare/es/compare/shiseido-vs-isdin
- Canada: https://lovi.care/skincare/ca/compare/shiseido-vs-isdin
- Australia: https://lovi.care/skincare/au/compare/shiseido-vs-isdin
- Singapore: https://lovi.care/skincare/sg/compare/shiseido-vs-isdin
- Saudi Arabia: https://lovi.care/skincare/sa/compare/shiseido-vs-isdin
- United Arab Emirates: https://lovi.care/skincare/ae/compare/shiseido-vs-isdin