# Sesderma vs Deconstruct Page: https://lovi.care/skincare/it/compare/sesderma-vs-deconstruct The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy. Sesderma and Deconstruct are two distinct skincare lines known for distinct formulations and heritages. The Spanish enterprise established in 1989 features advanced [serums](https://lovi.care/skincare/it/ingredients/serum) and meticulously engineered formulas with botanical [extracts](https://lovi.care/skincare/it/ingredients/extract) and active compounds that suit sensitive, hyperpigmented, and aging skin types best. Meanwhile, the Indian maker founded in 2020 offers reliable sunscreens and scientifically sound formulas with lightweight textures that suit balanced, oily, and acne-prone skin best. While both brands refine skin texture and promote a radiant complexion, they differ through targeted solutions such as the Azelac RU Serum and the Gel Sunscreen. Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026. [skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html) Deconstruct is an Indian skincare brand founded in 2020 and owned by Baypure Lifestyle Private Limited. [pitchbook.com](https://pitchbook.com/profiles/company/471592-90) [tracxn.com](https://tracxn.com/d/companies/deconstruct/__PiBQwt0O1m7tQKw7GJJTTNu8kfLoy_-Czaz7v2StPU0) [beautymatter.com](https://beautymatter.com/articles/dtc-indian-skincare-start-up-deconstruct-raises-7-7-million) This page compares some of the most popular Sesderma and Deconstruct products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg91d4609949). ### Popular Sesderma vs Deconstruct products #### Sesderma - [Azelac RU Serum](https://lovi.care/skincare/it/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€46.00 at Notino](https://www.notino.it/sesderma/azelac-ru-siero-depigmentante/p-514983/) #### Deconstruct - [Gel Sunscreen](https://lovi.care/skincare/it/p/deconstruct/gel-sunscreen/for/dark-spots) — High fit ## Questions and answers ### Sesderma or Deconstruct: which is better? Deconstruct has a High Lovi fit for sensitive skin and every product on this page lists no fragrance, whereas Sesderma has an Average Lovi fit for sensitive skin and includes fragrance in its [serum](https://lovi.care/skincare/it/ingredients/serum). ### What is the difference between Sesderma and Deconstruct? Sesderma and Deconstruct differ in their product selection and fragrance content on this page, as Sesderma features a scented Azelac RU Serum with High Lovi fit for acne-prone and dark spot skin, while Deconstruct offers an unscented Gel Sunscreen that achieves a High Lovi fit across acne-prone, dark spot, sensitive, and mature skin types. ### Which is more affordable, Sesderma or Deconstruct? The page facts do not mention pricing or affordability for either Sesderma or Deconstruct. ### Which causes fewer breakouts, Sesderma or Deconstruct? Deconstruct Gel Sunscreen has a High Lovi fit for acne-prone skin, whereas Sesderma Azelac RU Serum has an Average fit, making Deconstruct more likely to help prevent breakouts. Additionally, every product from Deconstruct on this page lists no fragrance, while the Sesderma product contains fragrance. ### Where were Sesderma and Deconstruct founded and in what years? Sesderma was founded in Spain in 1989, while Deconstruct was founded in India in 2020. ### How does the Lovi fit level of Sesderma's Azelac RU Serum compare to Deconstruct's Gel Sunscreen for dry sensitive skin? For dry sensitive skin, Lovi rates Sesderma's Azelac RU Serum as Low, while Deconstruct's Gel Sunscreen receives a higher fit level of Average. ### Which of the two brands has fragrance listed in its products on this page? Sesderma has fragrance listed in its products on this page, as its Azelac RU Serum includes fragrance. In contrast, every Deconstruct product on this page lists no fragrance. ## Research behind their key ingredients - [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000 - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007 - [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004 - [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017 - [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013 - [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987 - [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998 - [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025 - [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021 - [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024 - [Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin](https://pubmed.ncbi.nlm.nih.gov/39138602/) Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025 - [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate · Archives of Dermatological Research, 2024 ## The brands - Spanish skincare: [Sesderma](https://lovi.care/skincare/it/brands/sesderma) - Indian skincare: [Deconstruct](https://lovi.care/skincare/it/brands/deconstruct) ## More comparisons - [SKIN1004 vs Sesderma](https://lovi.care/skincare/it/compare/skin1004-vs-sesderma) - [SKIN1004 vs Deconstruct](https://lovi.care/skincare/it/compare/skin1004-vs-deconstruct) - [Anua vs Sesderma](https://lovi.care/skincare/it/compare/anua-vs-sesderma) - [Anua vs Deconstruct](https://lovi.care/skincare/it/compare/anua-vs-deconstruct) - [Medicube vs Sesderma](https://lovi.care/skincare/it/compare/medicube-vs-sesderma) - [Medicube vs Deconstruct](https://lovi.care/skincare/it/compare/medicube-vs-deconstruct) - [The Ordinary vs Sesderma](https://lovi.care/skincare/it/compare/the-ordinary-vs-sesderma) - [The Ordinary vs Deconstruct](https://lovi.care/skincare/it/compare/the-ordinary-vs-deconstruct) - [Beauty of Joseon vs Sesderma](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-sesderma) - [Beauty of Joseon vs Deconstruct](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-deconstruct) - [COSRX vs Sesderma](https://lovi.care/skincare/it/compare/cosrx-vs-sesderma) - [COSRX vs Deconstruct](https://lovi.care/skincare/it/compare/cosrx-vs-deconstruct) - [CeraVe vs Sesderma](https://lovi.care/skincare/it/compare/cerave-vs-sesderma) - [CeraVe vs Deconstruct](https://lovi.care/skincare/it/compare/cerave-vs-deconstruct) - [La Roche-Posay vs Sesderma](https://lovi.care/skincare/it/compare/la-roche-posay-vs-sesderma) - [La Roche-Posay vs Deconstruct](https://lovi.care/skincare/it/compare/la-roche-posay-vs-deconstruct) - [Dr. Althea vs Sesderma](https://lovi.care/skincare/it/compare/dr-althea-vs-sesderma) - [Dr. Althea vs Deconstruct](https://lovi.care/skincare/it/compare/dr-althea-vs-deconstruct) - [Some By Mi vs Sesderma](https://lovi.care/skincare/it/compare/some-by-mi-vs-sesderma) - [Some By Mi vs Deconstruct](https://lovi.care/skincare/it/compare/some-by-mi-vs-deconstruct) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/sesderma-vs-deconstruct - United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-deconstruct - Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-deconstruct - Germany: https://lovi.care/skincare/de/compare/sesderma-vs-deconstruct - France: https://lovi.care/skincare/fr/compare/sesderma-vs-deconstruct - Italy: https://lovi.care/skincare/it/compare/sesderma-vs-deconstruct (this page) - Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-deconstruct - Spain: https://lovi.care/skincare/es/compare/sesderma-vs-deconstruct - Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-deconstruct - Australia: https://lovi.care/skincare/au/compare/sesderma-vs-deconstruct - Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-deconstruct - Saudi Arabia: https://lovi.care/skincare/sa/compare/sesderma-vs-deconstruct - United Arab Emirates: https://lovi.care/skincare/ae/compare/sesderma-vs-deconstruct