# Sebamed vs Trilogy

Page: https://lovi.care/skincare/it/compare/sebamed-vs-trilogy

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Sebamed and Trilogy are thoughtful skincare brands celebrated for their gentle cleansers and nourishing moisturizers built on reliable, high-performing formulas. The German enterprise relies on scientifically balanced, skin-neutral pH compositions that suit sensitive, reactive, and problematic skin, whereas the other line suits dry, balanced, and sensitive skin types best. While both brands champion barrier health, they differ in their specific targeted concerns and ingredient philosophies, with the former featuring standout solutions like the Facial Cleanser and Clear Face Care Gel, and the latter offering distinct options such as the [Vitamin C](https://lovi.care/skincare/it/ingredients/vitamin-c) Ceramide Night Cream, [Rosehip](https://lovi.care/skincare/it/ingredients/rosehip-oil) Cream Cleanser, and Line Smoothing Day Cream.

Sebamed is a German skincare brand founded in 1967 and owned by Sebapharma GmbH & Co. KG.

[sebamed.ae](https://sebamed.ae/en/article/2/Sebapharma) [sebamed.com](https://sebamed.com/en/info/company/about-us/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Sebamed) [de.wikipedia.org](https://de.wikipedia.org/wiki/Sebamed)

This page compares some of the most popular Sebamed and Trilogy products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg37251304be).

### Popular Sebamed vs Trilogy products

#### Sebamed

- [Clear Face Care Gel](https://lovi.care/skincare/it/p/sebamed/clear-face-care-gel/for/oily-acne-prone-skin) — High fit — [€8.40 at Amazon](https://www.amazon.it/dp/B0GWMZBMSY?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Facial Cleanser](https://lovi.care/skincare/it/p/sebamed/facial-cleanser/for/combination-skin) — High fit

#### Trilogy

- [Rosehip Cream Cleanser](https://lovi.care/skincare/it/p/trilogy/rosehip-cream-cleanser/for/sensitive-skin) — High fit
- [Line Smoothing Day Cream](https://lovi.care/skincare/it/p/trilogy/line-smoothing-day-cream/for/dry-skin) — High fit
- [Vitamin C Ceramide Night Cream](https://lovi.care/skincare/it/p/trilogy/vitamin-c-ceramide-night-cream/for/mature-skin) — High fit

## Questions and answers

### Sebamed or Trilogy: which is better?

Sebamed offers fragrance-free choices across all the products on this page, while Trilogy includes fragrance in some of its formulas. Lovi rates Sebamed as having High fit for oily acne-prone skin, and Trilogy as having High fit for dry and mature skin types.

### What is the difference between Sebamed and Trilogy?

Sebamed has a High Lovi fit for oily and acne-prone skin with fragrance-free products on this page, whereas Trilogy features hydrating and brightening moisturizers with some scented formulas.

### Sebamed or Trilogy: which cleanser is better?

For sensitive skin, Trilogy [Rosehip](https://lovi.care/skincare/it/ingredients/rosehip-oil) Cream Cleanser and Sebamed Facial Cleanser both receive a High Lovi fit. However, Sebamed has the advantage that every product on this page lists no fragrance in its ingredients.

### Which is more affordable, Sebamed or Trilogy?

The page does not provide pricing information for either Sebamed or Trilogy, so it is not possible to say which brand is more affordable.

### Which causes fewer breakouts, Sebamed or Trilogy?

Sebamed has a High Lovi fit for oily acne-prone and acne-prone skin across the products on this page, while Trilogy has only Average fits for those skin types.

### Between Sebamed and Trilogy, which brand offers fragrance-free products?

Every product from Sebamed on this page lists no fragrance in its ingredients, whereas only one of the three Trilogy products does. Therefore, Sebamed is the more reliable choice if you want to avoid added scents across the entire page.

### How do the founding years and corporate ownership of Sebamed and Trilogy compare?

Sebamed was founded in 1967 in Germany and is owned by Sebapharma GmbH & Co. KG, while Trilogy was founded in 2002 and has been owned by CITIC Capital Holdings Limited since 2018.

### What are the main review highlights regarding Trilogy skincare products?

Reviewers mostly mention hydrating and brightening moisturizers as a highlight of the Trilogy products on this page. However, they also frequently note complaints about product performance and formulation.

### Sebamed or Trilogy: which moisturizer is better?

Both brands offer solid options, but Sebamed's Clear Face Care Gel gives a High fit for oily acne-prone skin while Trilogy's [Vitamin C](https://lovi.care/skincare/it/ingredients/vitamin-c) Ceramide Night Cream and Line Smoothing Day Cream provide High fits for dry and mature skin. Trilogy reviewers frequently mention hydrating and brightening benefits alongside some product performance complaints.

[Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/) [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

## Research behind their key ingredients

- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel bark extract · Phytochemistry, 2001
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Topical Almond Oil for Prevention of Pressure Injuries: A Single-Blinded Comparison Study](https://pubmed.ncbi.nlm.nih.gov/32379165/) Prunus amygdalus dulcis oil · Journal of Wound, Ostomy, and Continence Nursing, 2020
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Monocentric, Vehicle-Controlled, Double-Blind Study to Assess the Short- and Long-Term Effects of a Ceramide NP C15-Containing Emollient on the Skin Microbiome and the Skin Barrier Function in Sensitive Skin](https://pubmed.ncbi.nlm.nih.gov/41758783/) Ceramide iii · Skin Pharmacology and Physiology, 2026

## The brands

- German skincare: [Sebamed](https://lovi.care/skincare/it/brands/sebamed)
- Skincare: [Trilogy](https://lovi.care/skincare/it/brands/trilogy)

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- [The Ordinary vs Sebamed](https://lovi.care/skincare/it/compare/the-ordinary-vs-sebamed)
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- [CeraVe vs Sebamed](https://lovi.care/skincare/it/compare/cerave-vs-sebamed)
- [CeraVe vs Trilogy](https://lovi.care/skincare/it/compare/cerave-vs-trilogy)
- [La Roche-Posay vs Sebamed](https://lovi.care/skincare/it/compare/la-roche-posay-vs-sebamed)
- [La Roche-Posay vs Trilogy](https://lovi.care/skincare/it/compare/la-roche-posay-vs-trilogy)
- [Dr. Althea vs Sebamed](https://lovi.care/skincare/it/compare/dr-althea-vs-sebamed)
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- [Some By Mi vs Sebamed](https://lovi.care/skincare/it/compare/some-by-mi-vs-sebamed)
- [Some By Mi vs Trilogy](https://lovi.care/skincare/it/compare/some-by-mi-vs-trilogy)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/sebamed-vs-trilogy
- United Kingdom: https://lovi.care/skincare/uk/compare/sebamed-vs-trilogy
- Ireland: https://lovi.care/skincare/ie/compare/sebamed-vs-trilogy
- Germany: https://lovi.care/skincare/de/compare/sebamed-vs-trilogy
- France: https://lovi.care/skincare/fr/compare/sebamed-vs-trilogy
- Italy: https://lovi.care/skincare/it/compare/sebamed-vs-trilogy (this page)
- Netherlands: https://lovi.care/skincare/nl/compare/sebamed-vs-trilogy
- Spain: https://lovi.care/skincare/es/compare/sebamed-vs-trilogy
- Canada: https://lovi.care/skincare/ca/compare/sebamed-vs-trilogy
- Australia: https://lovi.care/skincare/au/compare/sebamed-vs-trilogy
- Singapore: https://lovi.care/skincare/sg/compare/sebamed-vs-trilogy
- Saudi Arabia: https://lovi.care/skincare/sa/compare/sebamed-vs-trilogy
- United Arab Emirates: https://lovi.care/skincare/ae/compare/sebamed-vs-trilogy