# Rilastil vs ISDIN Isdinceutics

Page: https://lovi.care/skincare/it/compare/rilastil-vs-isdin-isdinceutics

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Rilastil and ISDIN Isdinceutics are respected European skincare lines known for gentle yet effective compositions. The Italian brand is warmly loved for its targeted [serums](https://lovi.care/skincare/it/ingredients/serum) and meticulously balanced formulas, while the Spanish brand, founded in 1975 and owned by Puig since 2027, is revered for its targeted eye products and advanced formulas. Both suit mature, dry, and sensitive skin best due to their gentle yet deeply nourishing approach. They differ primarily in their specialized problem solvers, where the standout choice for acne-prone skin from the first is the Acnestil, and the standout K-Ox Eyes from the second offers noticeable relief for acne-prone skin.

ISDIN Isdinceutics is a Spanish skincare brand founded in 1975 and owned by Puig since 2027.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/)

This page compares some of the most popular Rilastil and ISDIN Isdinceutics products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg86f813dc40).

### Popular Rilastil vs ISDIN Isdinceutics products

#### ISDIN Isdinceutics

- [K-Ox Eyes](https://lovi.care/skincare/it/p/isdin-isdinceutics/k-ox-eyes/for/dry-skin) — High fit

#### Rilastil

- [Acnestil](https://lovi.care/skincare/it/p/rilastil/acnestil/for/oily-skin) — Average fit

## Questions and answers

### Rilastil or ISDIN Isdinceutics: which is better?

ISDIN Isdinceutics fits dry, sensitive, and mature skin at a High level with its K-Ox Eyes product, whereas the products on this page from Rilastil achieve only Average or lower fits across skin types. ISDIN Isdinceutics includes fragrance in its formulation, while every Rilastil product on this page lists no fragrance.

### What is the difference between Rilastil and ISDIN Isdinceutics?

Rilastil has an average fit for oily and acne-prone skin with its fragrance-free [serum](https://lovi.care/skincare/it/ingredients/serum), whereas ISDIN Isdinceutics achieves a high fit for dry, sensitive, and mature skin with its scented eye product.

### Which is more affordable, Rilastil or ISDIN Isdinceutics?

Neither Rilastil nor ISDIN Isdinceutics can be compared for affordability because the provided page facts do not include price information for either brand.

### Which causes fewer breakouts, Rilastil or ISDIN Isdinceutics?

Rilastil and ISDIN Isdinceutics both have an average Lovi fit for acne-prone skin on this page, but every product on the Rilastil page lists no fragrance, whereas the ISDIN Isdinceutics eye product on this page includes fragrance that may irritate sensitive skin.

### Which brand was founded earlier, Rilastil or ISDIN Isdinceutics?

Rilastil was founded earlier, in 1972, while ISDIN Isdinceutics was founded in 1975 in Spain.

### Do either Rilastil or ISDIN Isdinceutics products contain fragrance?

ISDIN Isdinceutics contains fragrance in its products on this page, as K-Ox Eyes lists fragrance in its ingredients. In contrast, Rilastil has no fragrance listed in the ingredients of every product on this page.

### Which company owns Rilastil?

Istituto Ganassini owns Rilastil.

## Research behind their key ingredients

- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage](https://pubmed.ncbi.nlm.nih.gov/21699266/) Chrysin · Journal of Agricultural and Food Chemistry, 2011
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation](https://pubmed.ncbi.nlm.nih.gov/19566395/) Ascorbyl palmitate · Journal of Microencapsulation, 2010
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- Skincare: [Rilastil](https://lovi.care/skincare/it/brands/rilastil)
- Spanish skincare: [ISDIN Isdinceutics](https://lovi.care/skincare/it/brands/isdin-isdinceutics)

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- [La Roche-Posay vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/la-roche-posay-vs-isdin-isdinceutics)
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- [Some By Mi vs Rilastil](https://lovi.care/skincare/it/compare/some-by-mi-vs-rilastil)
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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/rilastil-vs-isdin-isdinceutics
- United Kingdom: https://lovi.care/skincare/uk/compare/rilastil-vs-isdin-isdinceutics
- Ireland: https://lovi.care/skincare/ie/compare/rilastil-vs-isdin-isdinceutics
- Germany: https://lovi.care/skincare/de/compare/rilastil-vs-isdin-isdinceutics
- France: https://lovi.care/skincare/fr/compare/rilastil-vs-isdin-isdinceutics
- Italy: https://lovi.care/skincare/it/compare/rilastil-vs-isdin-isdinceutics (this page)
- Netherlands: https://lovi.care/skincare/nl/compare/rilastil-vs-isdin-isdinceutics
- Spain: https://lovi.care/skincare/es/compare/rilastil-vs-isdin-isdinceutics
- Canada: https://lovi.care/skincare/ca/compare/rilastil-vs-isdin-isdinceutics
- Australia: https://lovi.care/skincare/au/compare/rilastil-vs-isdin-isdinceutics
- Singapore: https://lovi.care/skincare/sg/compare/rilastil-vs-isdin-isdinceutics
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