# Medicube vs Grown Alchemist

Page: https://lovi.care/skincare/it/compare/medicube-vs-grown-alchemist

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Medicube and Grown Alchemist are distinct skincare brands offering thoughtfully formulated products for varied skin needs. The Korean brand founded in 2016 features moisturizers, [serums](https://lovi.care/skincare/it/ingredients/serum), toners, and masks with [niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide), [collagen](https://lovi.care/skincare/it/ingredients/collagen), and [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) to suit dry and oily acne-prone skin. Meanwhile, the other brand is beloved for cleansers and serums that suit sensitive, dry, and combination skin. While both deliver targeted care for concerns like acne, dark spots, and aging, they differ through distinct active ingredients and formulation traditions.

Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..

[medicubereviews.co.uk](https://medicubereviews.co.uk/medicube/story/) [glossy.co](https://www.glossy.co/beauty/medicubes-founder-on-the-products-and-people-that-fueled-the-k-beauty-brands-booming-year/)

This page compares some of the most popular Medicube and Grown Alchemist products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg6280dc9911).

### Popular Medicube vs Grown Alchemist products

#### Medicube

- [Zero Pore Pad](https://lovi.care/skincare/it/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [€17.15 at Amazon](https://www.amazon.it/dp/B09V7Z4TJG?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [PDRN Pink Peptide Serum](https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [€16.60 at Amazon](https://www.amazon.it/dp/B0DBF65JYY?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Collagen Jelly Cream](https://lovi.care/skincare/it/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [€19.12 at Amazon](https://www.amazon.it/dp/B0CM2PPNMW?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Collagen Night Wrapping Mask](https://lovi.care/skincare/it/p/medicube/collagen-night-wrapping-mask/for/dry-skin) — High fit — [€17.15 at Amazon](https://www.amazon.it/dp/B0BRMYHMS5?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [PDRN Pink Collagen Gel Mask](https://lovi.care/skincare/it/p/medicube/pdrn-pink-collagen-gel-mask/for/dry-sensitive-skin) — High fit — [€16.08 at Amazon](https://www.amazon.it/dp/B0DGTMR754?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [DEEP VITA-C CAPSULE CREAM](https://lovi.care/skincare/it/p/medicube/deep-vita-c-capsule-cream/for/sensitive-skin) — Average fit — [€17.49 at Amazon](https://www.amazon.it/dp/B0D2Z3GGCY?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [TRIPLE COLLAGEN CREAM](https://lovi.care/skincare/it/p/medicube/triple-collagen-cream/for/mature-skin) — Average fit — [€28.99 at Amazon](https://www.amazon.it/dp/B0DLG3S62C?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Zero Foam Cleanser](https://lovi.care/skincare/it/p/medicube/zero-foam-cleanser/for/dry-skin) — Superior fit — [€14.50 at Amazon](https://www.amazon.it/dp/B09C1B7BH5?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

#### Grown Alchemist

- [Gentle Gel Facial Cleanser](https://lovi.care/skincare/it/p/grown-alchemist/gentle-gel-facial-cleanser/for/dry-sensitive-skin) — Average fit
- [Hydra-Restore Cream Cleanser](https://lovi.care/skincare/it/p/grown-alchemist/hydra-restore-cream-cleanser/for/sensitive-skin) — High fit — [€44.00 at Amazon](https://www.amazon.it/dp/B00G3J8ISI?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Instant Smoothing Serum](https://lovi.care/skincare/it/p/grown-alchemist/instant-smoothing-serum/for/dry-sensitive-skin) — Average fit

## People Say

Medicube

Grown Alchemist

- Hydration, Moisture, and Plumping Mostly Mentioned Often Mentioned “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum” “glass skin — Medicube PDRN Pink Collagen Gel Mask” “woke up with baby soft skin — Medicube Collagen Jelly Cream” “Skin version of chugging water — Grown Alchemist Instant Smoothing Serum”
- Soothing and Gentle Formulas Often Mentioned Mostly Mentioned “Perfect for sensitive skin — Grown Alchemist Gentle Gel Facial Cleanser” “calms my skin down — Grown Alchemist Hydra-Restore Cream Cleanser” “refreshing sensation — Medicube PDRN Pink Collagen Gel Mask”
- Non-Stripping Formula Not noted Mostly Mentioned “Doesn't dry out my skin — Grown Alchemist Gentle Gel Facial Cleanser” “doesn't strip at all — Grown Alchemist Hydra-Restore Cream Cleanser”
- Luxurious Texture and Feel Rarely Noted Mostly Mentioned “silkiest cleanser — Grown Alchemist Hydra-Restore Cream Cleanser” “Very light weight — Grown Alchemist Instant Smoothing Serum” “Rich but absorbs well — Medicube TRIPLE COLLAGEN CREAM”
- Pleasant Scent Not noted Mostly Mentioned “Smells amazing — Grown Alchemist Gentle Gel Facial Cleanser” “smell is divine — Grown Alchemist Hydra-Restore Cream Cleanser”
- Deep Cleansing and Lather Sometimes Noted Often Mentioned “Gets everything nice and clean — Grown Alchemist Gentle Gel Facial Cleanser” “Pores drastically reduced — Medicube Zero Foam Cleanser”
- High Price and Cost Sometimes Noted Often Mentioned “tube is tiny for the price — Medicube Collagen Night Wrapping Mask” “price is steep — Medicube PDRN Pink Collagen Gel Mask” “price is a bit steep — Medicube Red Succinic Acid Peeling Pad” “expensive for what it is — Grown Alchemist Hydra-Restore Cream Cleanser”
- Removal and Application Issues Sometimes Noted Often Mentioned “messy — Medicube PDRN Pink Collagen Gel Mask” “lifted around the nose/eyes — Medicube PDRN Pink Collagen Gel Mask” “didn't remove deep blackheads — Medicube Zero Pore Blackhead Mud Mask” “Isn't going to be your makeup remover — Grown Alchemist Gentle Gel Facial Cleanser”
- Strong or Unpleasant Fragrance and Scent Often Mentioned Often Mentioned “slightly fishy smell — Medicube PDRN Pink Peptide Serum” “smells like old lady perfume — Medicube Collagen Jelly Cream” “Too perfumy notes — Grown Alchemist Gentle Gel Facial Cleanser” “smells medicinal — Grown Alchemist Hydra-Restore Cream Cleanser”

## Questions and answers

### Medicube or Grown Alchemist: which is better?

Medicube offers superior hydration and plumping for the products on this page, whereas Grown Alchemist provides gentler formulas. [Niacinamide](https://lovi.care/skincare/it/ingredients/niacinamide) helps control skin aging and pigmentation.

[Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/) [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What is the difference between Medicube and Grown Alchemist?

Medicube offers a wider selection of products focused on hydration and plumping with ingredients like niacinamide and [collagen](https://lovi.care/skincare/it/ingredients/collagen), whereas Grown Alchemist specializes in gentle, non-stripping cleansers with completely fragrance-free formulas. Medicube achieves a Superior fit level for dry skin and oily acne-prone skin, while Grown Alchemist products generally reach an Average or High fit across skin types.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/)

### Medicube or Grown Alchemist: which cleanser is better?

Medicube offers cleansers like the Zero Foam Cleanser with a Superior Lovi fit for dry skin, while Grown Alchemist features the Hydra-Restore Cream Cleanser with a High Lovi fit for sensitive skin.

### Which is more affordable, Medicube or Grown Alchemist?

Grown Alchemist is more affordable, whereas high price and cost are drawbacks frequently noted for Medicube.

### Which causes fewer breakouts, Medicube or Grown Alchemist?

Grown Alchemist is generally known for soothing and gentle formulas, whereas Medicube has products that are reported to sometimes cause irritation and breakouts.

### Which brand has more products containing fragrance, Medicube or Grown Alchemist?

Medicube has more products containing fragrance, as 23 of its 25 products on this page list no fragrance while 2 products do, whereas every product on the Grown Alchemist page lists no fragrance in its ingredients.

### Which products from Medicube achieve a Superior Lovi fit level for mature skin?

Medicube products achieving a Superior Lovi fit level for mature skin include the Collagen Jelly Cream, AGE-R Booster Gel, and Deep Lifting Peptide Eye Cream.

### How do the founding years and countries of origin compare between Medicube and Grown Alchemist?

Medicube was founded in 2016 in South Korea, while Grown Alchemist was founded in 2008.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate](https://pubmed.ncbi.nlm.nih.gov/11766131/) Benzyl alcohol · International Journal of Toxicology, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate molecule · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study](https://pubmed.ncbi.nlm.nih.gov/37377400/) Exosome cica · Journal of Cosmetic Dermatology, 2023
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Vitamin c derivatives · Experimental Dermatology, 2003
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Aha · Journal of Dermatological Science, 2017
- [Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics](https://pubmed.ncbi.nlm.nih.gov/35223163/) Collagen, Water-soluble collagen · Dermatology Practical & Conceptual, 2022
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005
- [Tea tree oil reduces histamine-induced skin inflammation](https://pubmed.ncbi.nlm.nih.gov/12452873/) Tree · The British Journal of Dermatology, 2002
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract, Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Use of Collagen in Cosmetic Products](https://pubmed.ncbi.nlm.nih.gov/38534748/) Collagen, Water-soluble collagen · Current Issues in Molecular Biology, 2024
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica flower extract · Journal of Ethnopharmacology, 2007
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Protective effects of Camellia japonica flower extract against urban air pollutants](https://pubmed.ncbi.nlm.nih.gov/30691451/) Camellia japonica flower extract · BMC Complementary and Alternative Medicine, 2019
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Development and photoprotective effect of a sunscreen containing the antioxidants Spirulina and dimethylmethoxy chromanol on sun-induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28341613/) Dimethylmethoxy chromanol · European Journal of Pharmaceutical Sciences, 2017
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Hydrolyzed Collagen Induces an Anti-Inflammatory Response That Induces Proliferation of Skin Fibroblast and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/36501011/) Collagen extract · Nutrients, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Vitamin c derivatives · Photochemistry and Photobiology, 2021
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid, Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract, Madecassoside, Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of olive leaf extract-containing cream for facial rejuvenation: A pilot study](https://pubmed.ncbi.nlm.nih.gov/32333467/) Olive leaf extract · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine](https://pubmed.ncbi.nlm.nih.gov/34284096/) Sophora angustifolia root extract, Sophora flavescens root extract · European Journal of Pharmaceutical Sciences, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Lifting peptide · Journal of the European Academy of Dermatology and Venereology, 2016
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis flower extract · Biomaterials Advances, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors](https://pubmed.ncbi.nlm.nih.gov/33081083/) Rose bud · Molecules, 2020
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [New clinical approach in facial mild-moderate acne: Re-stabilization of skin microbiota balance with a topical biotechnological phytocomplex](https://pubmed.ncbi.nlm.nih.gov/39205505/) Succinic acid · Journal of Cosmetic Dermatology, 2024
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging](https://pubmed.ncbi.nlm.nih.gov/20883292/) Willow bark extract · Journal of Cosmetic Dermatology, 2010
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Noninvasive evaluation of the influence of aucubin-containing cosmetic macroemulsion on selected skin parameters](https://pubmed.ncbi.nlm.nih.gov/32750209/) Plantago extract · Journal of Cosmetic Dermatology, 2021
- [Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract](https://pubmed.ncbi.nlm.nih.gov/33410284/) Camellia japonica flower extract · FEBS Open Bio, 2021
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial](https://pubmed.ncbi.nlm.nih.gov/37726676/) Portulaca oleracea extract · BMC Oral Health, 2023
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e · Arzneimittel-Forschung, 1998
- [Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins](https://pubmed.ncbi.nlm.nih.gov/17035721/) Grape seed extract · Skin Pharmacology and Physiology, 2007
- [Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract](https://pubmed.ncbi.nlm.nih.gov/35403355/) Grape seed extract · Journal of Cosmetic Dermatology, 2022
- [Rosa gallica and its active compound, cyanidin-3,5-O-diglucoside, improve skin hydration via the GLK signaling pathway](https://pubmed.ncbi.nlm.nih.gov/36573713/) Rose bud · BioFactors, 2023
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Clinical efficacy of herbal extract cream on the skin hydration, elasticity, thickness, and dermis density for aged skin: A randomized controlled double-blind study](https://pubmed.ncbi.nlm.nih.gov/30636339/) Botanical extracts · Journal of Cosmetic Dermatology, 2019
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Composition characterization and clinical efficacy study of a salmon egg extract](https://pubmed.ncbi.nlm.nih.gov/23738607/) Salmon egg extract · International Journal of Cosmetic Science, 2013
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate vitamin e · Scientific Reports, 2025
- [Ethanolamines permeate slowly across human skin ex vivo, but cause severe skin irritation at low concentrations](https://pubmed.ncbi.nlm.nih.gov/31435711/) Ethanolamine · Archives of Toxicology, 2019
- [Influence of the emulsifier on nanostructure and clinical application of liquid crystalline emulsions](https://pubmed.ncbi.nlm.nih.gov/36918671/) Camellia seed oil · Scientific Reports, 2023
- [Development and efficacy assessments of tea seed oil makeup remover](https://pubmed.ncbi.nlm.nih.gov/27988044/) Camellia seed oil · Annales Pharmaceutiques Francaises, 2017
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022
- [Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora](https://pubmed.ncbi.nlm.nih.gov/41516097/) Sodium dna, Pdrn polydeoxyribonucleotide · International Journal of Molecular Sciences, 2025
- [Polydeoxyribonucleotide-spermidine nanoparticles: Preparation, characterization, and verification of skin anti-aging efficacy](https://pubmed.ncbi.nlm.nih.gov/40840755/) Sodium dna · International Journal of Biological Macromolecules, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41319188/) Camellia seed oil · International Journal of Cosmetic Science, 2026
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026

## The brands

- Korean skincare: [Medicube](https://lovi.care/skincare/it/brands/medicube)
- Skincare: [Grown Alchemist](https://lovi.care/skincare/it/brands/grown-alchemist)

## More comparisons

- [SKIN1004 vs Medicube](https://lovi.care/skincare/it/compare/skin1004-vs-medicube)
- [SKIN1004 vs Grown Alchemist](https://lovi.care/skincare/it/compare/skin1004-vs-grown-alchemist)
- [Anua vs Medicube](https://lovi.care/skincare/it/compare/anua-vs-medicube)
- [Anua vs Grown Alchemist](https://lovi.care/skincare/it/compare/anua-vs-grown-alchemist)
- [Medicube vs The Ordinary](https://lovi.care/skincare/it/compare/medicube-vs-the-ordinary)
- [Medicube vs Beauty of Joseon](https://lovi.care/skincare/it/compare/medicube-vs-beauty-of-joseon)
- [Medicube vs COSRX](https://lovi.care/skincare/it/compare/medicube-vs-cosrx)
- [Medicube vs CeraVe](https://lovi.care/skincare/it/compare/medicube-vs-cerave)
- [Medicube vs La Roche-Posay](https://lovi.care/skincare/it/compare/medicube-vs-la-roche-posay)
- [Medicube vs Dr. Althea](https://lovi.care/skincare/it/compare/medicube-vs-dr-althea)
- [Medicube vs Some By Mi](https://lovi.care/skincare/it/compare/medicube-vs-some-by-mi)
- [Medicube vs Torriden](https://lovi.care/skincare/it/compare/medicube-vs-torriden)
- [Medicube vs celimax](https://lovi.care/skincare/it/compare/medicube-vs-celimax)
- [Medicube vs Purito](https://lovi.care/skincare/it/compare/medicube-vs-purito)
- [Medicube vs Cetaphil](https://lovi.care/skincare/it/compare/medicube-vs-cetaphil)
- [Medicube vs Paula's Choice](https://lovi.care/skincare/it/compare/medicube-vs-paula-s-choice)
- [Medicube vs Neutrogena](https://lovi.care/skincare/it/compare/medicube-vs-neutrogena)
- [Medicube vs Kiehl's](https://lovi.care/skincare/it/compare/medicube-vs-kiehl-s)
- [Medicube vs Caudalie](https://lovi.care/skincare/it/compare/medicube-vs-caudalie)
- [Medicube vs Dermalogica](https://lovi.care/skincare/it/compare/medicube-vs-dermalogica)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medicube-vs-grown-alchemist
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- Ireland: https://lovi.care/skincare/ie/compare/medicube-vs-grown-alchemist
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- Spain: https://lovi.care/skincare/es/compare/medicube-vs-grown-alchemist
- Canada: https://lovi.care/skincare/ca/compare/medicube-vs-grown-alchemist
- Australia: https://lovi.care/skincare/au/compare/medicube-vs-grown-alchemist
- Singapore: https://lovi.care/skincare/sg/compare/medicube-vs-grown-alchemist
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medicube-vs-grown-alchemist
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medicube-vs-grown-alchemist