# Galderma vs ISDIN Isdinceutics Page: https://lovi.care/skincare/it/compare/galderma-vs-isdin-isdinceutics The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy. Galderma and ISDIN Isdinceutics are two established dermatological houses, originating from Switzerland and Spain respectively, that offer targeted [serums](https://lovi.care/skincare/it/ingredients/serum) and specialized treatments. The Swiss brand is recognized for its focused acne-fighting topicals featuring ingredients like [benzoyl peroxide](https://lovi.care/skincare/it/ingredients/benzoyl-peroxide), while the Spanish house is revered for advanced formulas and eye care. Both brands cater effectively to distinct profiles, with the Swiss formulas suiting acne-prone skin best and the Spanish compositions favoring mature, dry, and sensitive skin. Ultimately, they differ in their core therapeutic approaches, balancing clinical acne management with restorative anti-aging care. Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG. [en.wikipedia.org](https://en.wikipedia.org/wiki/Galderma) ISDIN Isdinceutics is a Spanish skincare brand founded in 1975 and owned by Puig since 2027. [puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) This page compares some of the most popular Galderma and ISDIN Isdinceutics products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg974514c7bc). ### Popular Galderma vs ISDIN Isdinceutics products #### Galderma - [Epiduo Gel](https://lovi.care/skincare/it/p/galderma/epiduo-gel/for/acne-prone-skin) — High fit - [Benzac AC 5](https://lovi.care/skincare/it/p/galderma/benzac-ac-5/for/oily-acne-prone-skin) — High fit - [Benzac AC Mild Strength 2.5% Acne Gel](https://lovi.care/skincare/it/p/galderma/benzac-ac-mild-strength-2-5-acne-gel/for/oily-acne-prone-skin) — High fit #### ISDIN Isdinceutics - [K-Ox Eyes](https://lovi.care/skincare/it/p/isdin-isdinceutics/k-ox-eyes/for/dry-skin) — High fit ## Questions and answers ### Galderma or ISDIN Isdinceutics: which is better? Galderma is better for clearing acne since the products on this page help reduce breakouts, though they may cause dryness and irritation. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) ### What is the difference between Galderma and ISDIN Isdinceutics? Galderma is a Swiss brand offering effective fragrance-free acne-clearing [serums](https://lovi.care/skincare/it/ingredients/serum) that have a High Lovi fit for oily and acne-prone skin, though they may cause severe dryness and irritation. In contrast, the Spanish brand ISDIN Isdinceutics offers an eye product with fragrance that has a High Lovi fit for dry, sensitive, and mature skin. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) ### Which is more affordable, Galderma or ISDIN Isdinceutics? The provided page facts do not contain pricing information for either Galderma or ISDIN Isdinceutics, so it is not possible to determine which brand is more affordable. ### Which causes fewer breakouts, Galderma or ISDIN Isdinceutics? Galderma has High Lovi fit levels for acne-prone skin with the products on this page, whereas ISDIN Isdinceutics has an Average fit level. Galderma's products help clear acne, though reviewers note they may cause severe dryness or irritation. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) ### Which brand has products formulated without fragrance, Galderma or ISDIN Isdinceutics? Galderma has products formulated without fragrance, as every product on its page lists no fragrance in its ingredients, whereas the ISDIN Isdinceutics eye product includes fragrance. ### How do the founding countries and years of Galderma and ISDIN Isdinceutics compare? Galderma was founded in Switzerland in 1981, whereas ISDIN Isdinceutics was founded in Spain in 1975. ### What are the main negative side effects reported by reviewers for Galderma serums? Reviewers mostly mention that Galderma serums can cause severe dryness, peeling, irritation, and discomfort. ## Research behind their key ingredients - [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020 - [Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage](https://pubmed.ncbi.nlm.nih.gov/21699266/) Chrysin · Journal of Agricultural and Food Chemistry, 2011 - [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide, Benzoyl peroxide 25mg g · The Cochrane Database of Systematic Reviews, 2020 - [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020 - [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene · American Journal of Clinical Dermatology, 2018 - [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of Shoulder and Elbow Surgery, 2021 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide, Benzoyl peroxide 25mg g · American Journal of Clinical Dermatology, 2022 - [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene · Archives of Dermatological Research, 2022 - [Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15](https://pubmed.ncbi.nlm.nih.gov/32224894/) Silicon dioxide · Antioxidants, 2020 - [Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection](https://pubmed.ncbi.nlm.nih.gov/32395645/) Silicon dioxide · Heliyon, 2020 - [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023 - [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of the American Academy of Dermatology, 2023 - [Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/37367119/) Carbomer 940 · Gels, 2023 - [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022 - [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026 - [Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation](https://pubmed.ncbi.nlm.nih.gov/19566395/) Ascorbyl palmitate · Journal of Microencapsulation, 2010 - [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022 - [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026 ## The brands - Swiss skincare: [Galderma](https://lovi.care/skincare/it/brands/galderma) - Spanish skincare: [ISDIN Isdinceutics](https://lovi.care/skincare/it/brands/isdin-isdinceutics) ## More comparisons - [SKIN1004 vs Galderma](https://lovi.care/skincare/it/compare/skin1004-vs-galderma) - [SKIN1004 vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/skin1004-vs-isdin-isdinceutics) - [Anua vs Galderma](https://lovi.care/skincare/it/compare/anua-vs-galderma) - [Anua vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/anua-vs-isdin-isdinceutics) - [Medicube vs Galderma](https://lovi.care/skincare/it/compare/medicube-vs-galderma) - [Medicube vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/medicube-vs-isdin-isdinceutics) - [The Ordinary vs Galderma](https://lovi.care/skincare/it/compare/the-ordinary-vs-galderma) - [The Ordinary vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/the-ordinary-vs-isdin-isdinceutics) - [Beauty of Joseon vs Galderma](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-galderma) - [Beauty of Joseon vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-isdin-isdinceutics) - [COSRX vs Galderma](https://lovi.care/skincare/it/compare/cosrx-vs-galderma) - [COSRX vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/cosrx-vs-isdin-isdinceutics) - [CeraVe vs Galderma](https://lovi.care/skincare/it/compare/cerave-vs-galderma) - [CeraVe vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/cerave-vs-isdin-isdinceutics) - [La Roche-Posay vs Galderma](https://lovi.care/skincare/it/compare/la-roche-posay-vs-galderma) - [La Roche-Posay vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/la-roche-posay-vs-isdin-isdinceutics) - [Dr. Althea vs Galderma](https://lovi.care/skincare/it/compare/dr-althea-vs-galderma) - [Dr. Althea vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/dr-althea-vs-isdin-isdinceutics) - [Some By Mi vs Galderma](https://lovi.care/skincare/it/compare/some-by-mi-vs-galderma) - [Some By Mi vs ISDIN Isdinceutics](https://lovi.care/skincare/it/compare/some-by-mi-vs-isdin-isdinceutics) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/galderma-vs-isdin-isdinceutics - United Kingdom: https://lovi.care/skincare/uk/compare/galderma-vs-isdin-isdinceutics - Ireland: https://lovi.care/skincare/ie/compare/galderma-vs-isdin-isdinceutics - Germany: https://lovi.care/skincare/de/compare/galderma-vs-isdin-isdinceutics - France: https://lovi.care/skincare/fr/compare/galderma-vs-isdin-isdinceutics - Italy: https://lovi.care/skincare/it/compare/galderma-vs-isdin-isdinceutics (this page) - Netherlands: https://lovi.care/skincare/nl/compare/galderma-vs-isdin-isdinceutics - Spain: https://lovi.care/skincare/es/compare/galderma-vs-isdin-isdinceutics - Canada: https://lovi.care/skincare/ca/compare/galderma-vs-isdin-isdinceutics - Australia: https://lovi.care/skincare/au/compare/galderma-vs-isdin-isdinceutics - Singapore: https://lovi.care/skincare/sg/compare/galderma-vs-isdin-isdinceutics - Saudi Arabia: https://lovi.care/skincare/sa/compare/galderma-vs-isdin-isdinceutics - United Arab Emirates: https://lovi.care/skincare/ae/compare/galderma-vs-isdin-isdinceutics