# Clinique vs SK-II

Page: https://lovi.care/skincare/it/compare/clinique-vs-sk-ii

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Clinique and SK-II are established skincare houses that offer distinct approaches to complexion care through targeted moisturizers, [serums](https://lovi.care/skincare/it/ingredients/serum), and specialized treatments. The American brand, founded in 1968, relies on [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid), [glycerin](https://lovi.care/skincare/it/ingredients/glycerin), and [caffeine](https://lovi.care/skincare/it/ingredients/caffeine) to comfort dry sensitive skin and oily skin, whereas the Japanese counterpart, founded in 1980, anchors its luxurious formulations in pitera to balance dry skin and acne-prone skin. While both labels address specific concerns like dark spots and aging, they differ fundamentally in their heritage and signature ingredients.

Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Clinique) [elcompanies.com](https://www.elcompanies.com/en/who-we-are/our-heritage) [businesswire.com](https://www.businesswire.com/news/home/20261019083802/en/The-Este-Lauder-Companies-Appoints-Krista-Lee-Berger-Senior-Vice-President-Global-Marketing-Clinique) [glossy.co](https://www.glossy.co/beauty/glossy-pop-newsletter-clinique-launches-first-ever-creator-led-campaign/)

SK-II is a Japanese skincare brand founded in 1980 and owned by The Procter & Gamble Company since 1991.

[en.wikipedia.org](https://en.wikipedia.org/wiki/SK-II) [discoversk-ii.wixsite.com](https://discoversk-ii.wixsite.com/home/brand-history) [glossy.co](https://www.glossy.co/beauty/despite-strong-results-in-beauty-in-the-first-quarter-pg-will-eliminate-thousands-of-jobs/)

This page compares some of the most popular Clinique and SK-II products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg8180ea711a).

### Popular Clinique vs SK-II products

#### SK-II

- [Facial Treatment Essence](https://lovi.care/skincare/it/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [€173.08 at Amazon](https://www.amazon.it/dp/B000H723LU?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Facial Treatment Mask](https://lovi.care/skincare/it/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [€440.61 at Amazon](https://www.amazon.it/dp/B07C3QF2RQ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Facial Treatment Clear Lotion](https://lovi.care/skincare/it/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit
- [Skinpower Advanced Cream](https://lovi.care/skincare/it/p/sk-ii/skinpower-advanced-cream/for/mature-skin) — High fit — [€455.63 at Amazon](https://www.amazon.it/dp/B0CFW488TZ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Genoptics Ultraura Essence](https://lovi.care/skincare/it/p/sk-ii/genoptics-ultraura-essence/for/acne-prone-skin) — Superior fit
- [Facial Treatment Cleansing Oil](https://lovi.care/skincare/it/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit
- [Genoptics Spot Essence](https://lovi.care/skincare/it/p/sk-ii/genoptics-spot-essence/for/dark-spots) — Average fit

#### Clinique

- [moisture surge](https://lovi.care/skincare/it/p/clinique/moisture-surge/for/sensitive-skin) — High fit
- [Take The Day Off Cleansing Balm](https://lovi.care/skincare/it/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [€27.37 at Amazon](https://www.amazon.it/dp/B07D5C86RX?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Lotion+](https://lovi.care/skincare/it/p/clinique/dramatically-different-moisturizing-lotion/for/dry-skin) — Average fit — [€31.36 at Amazon](https://www.amazon.it/dp/B00CVZ3NJ2?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [All About Eyes](https://lovi.care/skincare/it/p/clinique/all-about-eyes/for/dry-skin) — High fit — [€35.99 at Amazon](https://www.amazon.it/dp/B001IZ0ZFQ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/it/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [€32.99 at Amazon](https://www.amazon.it/dp/B003JRI3OG?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/it/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [€88.99 at Amazon](https://www.amazon.it/dp/B09FG8TJDD?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Moisture Surge Overnight Mask](https://lovi.care/skincare/it/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [€29.39 at Amazon](https://www.amazon.it/dp/B00HSZRQQQ?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Clarifying Lotion 2](https://lovi.care/skincare/it/p/clinique/clarifying-lotion-2/for/oily-acne-prone-skin) — Average fit — [€32.00 at Amazon](https://www.amazon.it/dp/B000H74MNW?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

## People Say

Clinique

SK-II

- Hydration and Plumping Often Mentioned Mostly Mentioned “flooded my skin with moisture — SK-II Facial Treatment Mask” “skin feels deeply hydrated, plump, and smoother — SK-II Skinpower Advanced Cream” “Leaves skin soft, feels moisturized, does not dry out skin. — SK-II Facial Treatment Cleansing Oil” “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
- Lightweight and Fast Absorbing Often Mentioned Often Mentioned “sinks in immediately — Clinique moisture surge” “sinks in instantly — Clinique Dramatically Different Moisturizing Gel” “drinks right into the skin — SK-II Facial Treatment Essence” “Absorbs into the skin quickly. — SK-II Genoptics Ultraura Essence”
- Gentle for Sensitive Skin Mostly Mentioned Sometimes Noted “never irritated my eyes — Clinique All About Eyes” “No stinging eyes — Clinique Take The Day Off Cleansing Balm” “doesn't dry out — Clinique all about clean” “Watery consistency — SK-II Facial Treatment Clear Lotion”
- Smoother Skin and Texture Sometimes Noted Often Mentioned “skin feels soft as butter — SK-II Facial Treatment Essence” “pores became miraculously invisible — SK-II Facial Treatment Mask” “Smoother skin — SK-II Facial Treatment Clear Lotion” “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- Radiance and Glow Not noted Mostly Mentioned “gives a glass skin look — SK-II Facial Treatment Essence” “leaves me with a red carpet glow — SK-II Facial Treatment Mask” “My skin is glowing now. — SK-II Genoptics Ultraura Essence”
- Makeup Base Compatibility Often Mentioned Rarely Noted “Melts waterproof mascara — Clinique Take The Day Off Cleansing Balm” “foundation glides on — Clinique moisture surge” “holds concealer in place — Clinique All About Eyes” “Dissolves waterproof mascara, melts stubborn makeup, removes sunscreen easily. — SK-II Facial Treatment Cleansing Oil”
- High Price Often Mentioned Mostly Mentioned “jar is too small for the cost — Clinique moisture surge” “quite pricey — Clinique Smart Clinical Repair Wrinkle Correcting Serum” “Expensive for cleanser — Clinique Take The Day Off Cleansing Balm” “way too expensive — SK-II Facial Treatment Essence”
- Causes Breakouts Sometimes Noted Rarely Noted “caused tiny red bumps — SK-II Facial Treatment Essence” “Small bumps — SK-II Facial Treatment Clear Lotion” “did break out some while adjusting — SK-II Skinpower Advanced Cream” “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+”
- Lack of Results Not noted Often Mentioned “did absolutely nothing — SK-II Facial Treatment Essence”

### Clinique vs SK-II routines for dry skin

#### SK-II-focused routine

- Cleanser: [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [€9.19 at Amazon](https://www.amazon.it/dp/B07C5R51Q9?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [€15.16 at Amazon](https://www.amazon.it/dp/B08Q6WZ6J1?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/it/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [€173.08 at Amazon](https://www.amazon.it/dp/B000H723LU?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [€37.19 at Amazon](https://www.amazon.it/dp/B00JJZN1HG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/it/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€15.90 at Amazon](https://www.amazon.it/dp/B084Q16G8D?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [SKIN1004 Madagascar Centella Poremizing Fresh Ampoule](https://lovi.care/skincare/it/p/skin1004/madagascar-centella-poremizing-fresh-ampoule/for/dry-skin) — Superior fit — [€16.60 at Amazon](https://www.amazon.it/dp/B0B1JRGGLF?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Facial Treatment Mask](https://lovi.care/skincare/it/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [€440.61 at Amazon](https://www.amazon.it/dp/B07C3QF2RQ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [all about clean](https://lovi.care/skincare/it/p/clinique/all-about-clean/for/dry-skin) — Warning fit — [€34.00 at Amazon](https://www.amazon.it/dp/B002RBTB8C?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/it/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — [€15.16 at Amazon](https://www.amazon.it/dp/B08Q6WZ6J1?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Smart Clinical Repair Lifting Face + Neck Cream](https://lovi.care/skincare/it/p/clinique/smart-clinical-repair-lifting-face-neck-cream/for/dry-skin) — High fit — [€77.00 at Amazon](https://www.amazon.it/dp/B0CHXGY211?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/it/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [€37.19 at Amazon](https://www.amazon.it/dp/B00JJZN1HG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/it/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [€27.37 at Amazon](https://www.amazon.it/dp/B07D5C86RX?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/it/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/dry-skin) — Average fit — [€88.99 at Amazon](https://www.amazon.it/dp/B09FG8TJDD?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Moisture Surge Overnight Mask](https://lovi.care/skincare/it/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [€29.39 at Amazon](https://www.amazon.it/dp/B00HSZRQQQ?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 99% fit](https://lovi.care/skincare/it/skin/dry-skin)

### Clinique vs SK-II routines for oily skin

#### SK-II-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€24.75 at Amazon](https://www.amazon.it/dp/B0CRSJ46YD?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/it/p/sk-ii/facial-treatment-essence/for/oily-skin) — Average fit — [€173.08 at Amazon](https://www.amazon.it/dp/B000H723LU?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/it/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€19.50 at Amazon](https://www.amazon.it/dp/B09SN5B88W?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [L'Oreal Paris Revitalift 12% Vitamin C + E + Salicylic Serum](https://lovi.care/skincare/it/p/l-oreal-paris/revitalift-12-vitamin-c-e-salicylic-serum/for/oily-skin) — Superior fit — [€14.21 at Amazon](https://www.amazon.it/dp/B0BKLWC84G?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [Redness Solutions Soothing Cleanser](https://lovi.care/skincare/it/p/clinique/redness-solutions-soothing-cleanser/for/oily-skin) — Average fit — [€31.05 at Lookfantastic](https://www.lookfantastic.it/p/clinique-clinique-redness-solutionssoothing-cleanser-for-unisex-0/11144770/) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/oily-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/it/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [€32.99 at Amazon](https://www.amazon.it/dp/B003JRI3OG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/it/p/clinique/take-the-day-off-cleansing-balm/for/oily-skin) — Low fit — [€27.37 at Amazon](https://www.amazon.it/dp/B07D5C86RX?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Clarifying Lotion 2](https://lovi.care/skincare/it/p/clinique/clarifying-lotion-2/for/oily-skin) — Average fit — [€32.00 at Amazon](https://www.amazon.it/dp/B000H74MNW?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/it/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-skin) — Average fit — [€88.99 at Amazon](https://www.amazon.it/dp/B09FG8TJDD?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/it/skin/oily-skin)

### Clinique vs SK-II routines for combination skin

#### SK-II-focused routine

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/it/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — [€13.50 at Amazon](https://www.amazon.it/dp/B07RY6Q6QM?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/it/p/sk-ii/facial-treatment-essence/for/combination-skin) — High fit — [€173.08 at Amazon](https://www.amazon.it/dp/B000H723LU?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/it/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [€40.00 at Amazon](https://www.amazon.it/dp/B0DNJKPSB8?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/it/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€17.15 at Amazon](https://www.amazon.it/dp/B09V7Z4TJG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [NEOGEN Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — [€37.99 at Amazon](https://www.amazon.it/dp/B0B8MVX1PS?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

#### Clinique-focused routine

- Cleanser: [all about clean](https://lovi.care/skincare/it/p/clinique/all-about-clean/for/combination-skin) — Low fit — [€34.00 at Amazon](https://www.amazon.it/dp/B002RBTB8C?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/it/p/la-mer/the-tonic/for/combination-skin) — Superior fit — [€103.91 at Amazon](https://www.amazon.it/dp/B0CY5LW9DY?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/it/p/clinique/dramatically-different-moisturizing-gel/for/combination-skin) — Average fit — [€32.99 at Amazon](https://www.amazon.it/dp/B003JRI3OG?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/it/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€40.49 at Amazon](https://www.amazon.it/dp/B094QD62C2?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Take The Day Off Cleansing Balm](https://lovi.care/skincare/it/p/clinique/take-the-day-off-cleansing-balm/for/combination-skin) — Low fit — [€27.37 at Amazon](https://www.amazon.it/dp/B07D5C86RX?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Clarifying Lotion 2](https://lovi.care/skincare/it/p/clinique/clarifying-lotion-2/for/combination-skin) — Average fit — [€32.00 at Amazon](https://www.amazon.it/dp/B000H74MNW?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/it/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/combination-skin) — Average fit — [€88.99 at Amazon](https://www.amazon.it/dp/B09FG8TJDD?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/it/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€49.00 at Amazon](https://www.amazon.it/dp/B0D1YJN279?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/it/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€19.79 at Amazon](https://www.amazon.it/dp/B083X5R6VR?tag=lovi-care-web-routine0a-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/it/skin/combination-skin)

## Questions and answers

### Clinique or SK-II: which is better?

SK-II helps provide superior results across multiple skin types on the products on this page compared to Clinique. Topical [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) helps improve skin quality and hydration.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between Clinique and SK-II?

Clinique is better for sensitive skin, whereas SK-II offers superior routine fit for dry, oily, combination, acne-prone, mature, and dark spot skin types. Reviewers find that SK-II delivers better hydration, plumping, smoother skin, texture, and radiance, while Clinique is often noted for a high price point and lack of results.

### Clinique or SK-II for dry skin?

SK-II is the better choice for dry skin, offering a Superior routine fit compared to Clinique's Average fit.

### Clinique or SK-II: which moisturizer is better?

SK-II delivers Superior routine fit for moisturizers across multiple skin types on the products on this page, while Clinique offers High fit for dry sensitive skin and oily skin. Reviewers indicate that SK-II provides better hydration and plumping benefits.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, Clinique or SK-II?

Reviewers on this page frequently note a high price point for Clinique products, while SK-II reviewers do not mention price issues in the provided data. Lovi shows both brands offer extensive luxury ranges, but shoppers often discuss Clinique's cost.

### Between Clinique and SK-II, which brand performs better for mature skin?

Clinique and SK-II both have products that are a High fit for mature skin, but SK-II has a Superior routine fit for this skin type.

### Which skincare brand is gentler for sensitive skin, Clinique or SK-II?

Clinique is gentler for sensitive skin compared to SK-II. Lovi rates Clinique as having higher suitability for sensitive skin needs with gentle and effective cleansers, while review themes also show that Clinique does better for being gentle on sensitive skin.

### Clinique or SK-II: which brand provides better radiance and glow?

SK-II provides better radiance and glow than Clinique. Lovi rates SK-II as having a Superior routine fit for skin with dark spots, and reviewers highlight SK-II as doing better for radiance and glow.

### Clinique or SK-II for oily skin?

Both Clinique and SK-II are good options for oily skin, with Lovi giving SK-II a Superior fit and Clinique a High fit. The products on this page from Clinique feature oil-controlling and smoothing moisturizers, while SK-II offers hydration and plumping benefits.

[Skin Pharmacology and Physiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23075568/)

### Clinique or SK-II for sensitive skin?

Clinique is a better fit for sensitive skin, as Lovi rates its targeted products as High compared to SK-II's Average ratings. Reviewers also note that Clinique is more gentle for sensitive skin.

### Clinique or SK-II for acne-prone skin?

SK-II is a better fit for acne-prone skin, holding a Superior routine fit compared to Clinique's Average fit on this page. SK-II's products on this page help provide targeted care, while Clinique's options may be less specialized for this skin type.

## Research behind their key ingredients

- [Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology](https://pubmed.ncbi.nlm.nih.gov/19169201/) Squalene · Molecules, 2009
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Nicotinamide w, Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, D-pantothenyl alcohol · American Journal of Clinical Dermatology, 2002
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Micro-acid complex · Journal of Dermatological Science, 2017
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Protecting skin photoaging by NF-kappaB inhibitor](https://pubmed.ncbi.nlm.nih.gov/20540695/) Magnolia officinalis bark extract · Current Drug Metabolism, 2010
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Periodontology, 2009
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf water, Aloe barbadensis · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Effect of 30% Supramolecular Salicylic Acid Peel on Skin Microbiota and Inflammation in Patients with Moderate-to-Severe Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/36350527/) Micro-acid complex · Dermatology and Therapy, 2023
- [Systematic Study of Resveratrol Nanoliposomes Transdermal Delivery System for Enhancing Anti-Aging and Skin-Brightening Efficacy](https://pubmed.ncbi.nlm.nih.gov/36985709/) Polygonum cuspidatum root extract · Molecules, 2023
- [Role of Resveratrol in Regulating Cutaneous Functions](https://pubmed.ncbi.nlm.nih.gov/32382280/) Polygonum cuspidatum root extract · Evidence-based Complementary and Alternative Medicine, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Concentrated glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB](https://pubmed.ncbi.nlm.nih.gov/17346696/) Magnolia officinalis bark extract · European Journal of Pharmacology, 2007
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, D-pantothenyl alcohol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) D-pantothenyl alcohol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results](https://pubmed.ncbi.nlm.nih.gov/39810881/) Probiotic technology · Journal of Experimental Pharmacology, 2025
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2021
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide](https://pubmed.ncbi.nlm.nih.gov/19958429/) Undecylenoyl phenylalanine · Journal of Cosmetic Dermatology, 2009
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel extract · Journal of Cosmetic Science, 2018
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Dimethoxytolyl propylresorcinol · Journal of Cosmetic Dermatology, 2021
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Multi-peptides · Journal of Cosmetic Dermatology, 2010
- [Algae extract protection effect on oxidized protein level in human stratum corneum](https://pubmed.ncbi.nlm.nih.gov/15247018/) Algae extract · Annals of the New York Academy of Sciences, 2004
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Amended safety assessment of Sesamum indicum (sesame) seed oil, hydrogenated sesame seed oil, Sesamum indicum (sesame) oil unsaponifiables, and sodium sesameseedate](https://pubmed.ncbi.nlm.nih.gov/21772026/) Sesamum indicum oil · International Journal of Toxicology, 2011
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2022
- [Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin](https://pubmed.ncbi.nlm.nih.gov/20883290/) Sodium salicylate · Journal of Cosmetic Dermatology, 2010
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, D-pantothenyl alcohol · Journal of Cosmetic Dermatology, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride, Capric triglyceride · Life, 2023
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Effects of a Postbiotic Saccharomyces and Lactobacillus Ferment Complex on the Scalp Microbiome of Chinese Women with Sensitive Scalp Syndrome](https://pubmed.ncbi.nlm.nih.gov/37767337/) Lactobacillus ferment · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin](https://pubmed.ncbi.nlm.nih.gov/41224059/) Xanthan gum · International Journal of Biological Macromolecules, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study](https://pubmed.ncbi.nlm.nih.gov/36769815/) Galactomyces ferment filtrate, Pitera essence, Pitera ferment filtrate galactomyces ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate, Pitera · Journal of Clinical Medicine, 2023
- [The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/41668671/) Laminaria digitata extract · International Journal of Cosmetic Science, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter, Shea butter · Lasers in Medical Science, 2025
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Simmondsia chinensis (jojoba) cake fermentation: A new, sustainable technology for advanced skin and scalp care ingredients](https://pubmed.ncbi.nlm.nih.gov/42698229/) Lactobacillus ferment · International Journal of Cosmetic Science, 2026
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Galactomyces ferment filtrate, Sk-ii pitera concentrate, Galactomyces ferment filtrate pitera ferment filtrate · Skinmed, 2021

## The brands

- American skincare: [Clinique](https://lovi.care/skincare/it/brands/clinique)
- Japanese skincare: [SK-II](https://lovi.care/skincare/it/brands/sk-ii)

## More comparisons

- [SKIN1004 vs Clinique](https://lovi.care/skincare/it/compare/skin1004-vs-clinique)
- [SKIN1004 vs SK-II](https://lovi.care/skincare/it/compare/skin1004-vs-sk-ii)
- [Anua vs Clinique](https://lovi.care/skincare/it/compare/anua-vs-clinique)
- [Anua vs SK-II](https://lovi.care/skincare/it/compare/anua-vs-sk-ii)
- [Medicube vs Clinique](https://lovi.care/skincare/it/compare/medicube-vs-clinique)
- [Medicube vs SK-II](https://lovi.care/skincare/it/compare/medicube-vs-sk-ii)
- [The Ordinary vs Clinique](https://lovi.care/skincare/it/compare/the-ordinary-vs-clinique)
- [The Ordinary vs SK-II](https://lovi.care/skincare/it/compare/the-ordinary-vs-sk-ii)
- [Beauty of Joseon vs Clinique](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-clinique)
- [Beauty of Joseon vs SK-II](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-sk-ii)
- [COSRX vs Clinique](https://lovi.care/skincare/it/compare/cosrx-vs-clinique)
- [COSRX vs SK-II](https://lovi.care/skincare/it/compare/cosrx-vs-sk-ii)
- [CeraVe vs Clinique](https://lovi.care/skincare/it/compare/cerave-vs-clinique)
- [CeraVe vs SK-II](https://lovi.care/skincare/it/compare/cerave-vs-sk-ii)
- [La Roche-Posay vs Clinique](https://lovi.care/skincare/it/compare/la-roche-posay-vs-clinique)
- [La Roche-Posay vs SK-II](https://lovi.care/skincare/it/compare/la-roche-posay-vs-sk-ii)
- [Dr. Althea vs Clinique](https://lovi.care/skincare/it/compare/dr-althea-vs-clinique)
- [Dr. Althea vs SK-II](https://lovi.care/skincare/it/compare/dr-althea-vs-sk-ii)
- [Some By Mi vs Clinique](https://lovi.care/skincare/it/compare/some-by-mi-vs-clinique)
- [Some By Mi vs SK-II](https://lovi.care/skincare/it/compare/some-by-mi-vs-sk-ii)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/clinique-vs-sk-ii
- United Kingdom: https://lovi.care/skincare/uk/compare/clinique-vs-sk-ii
- Ireland: https://lovi.care/skincare/ie/compare/clinique-vs-sk-ii
- Germany: https://lovi.care/skincare/de/compare/clinique-vs-sk-ii
- France: https://lovi.care/skincare/fr/compare/clinique-vs-sk-ii
- Italy: https://lovi.care/skincare/it/compare/clinique-vs-sk-ii (this page)
- Netherlands: https://lovi.care/skincare/nl/compare/clinique-vs-sk-ii
- Spain: https://lovi.care/skincare/es/compare/clinique-vs-sk-ii
- Canada: https://lovi.care/skincare/ca/compare/clinique-vs-sk-ii
- Australia: https://lovi.care/skincare/au/compare/clinique-vs-sk-ii
- Singapore: https://lovi.care/skincare/sg/compare/clinique-vs-sk-ii
- Saudi Arabia: https://lovi.care/skincare/sa/compare/clinique-vs-sk-ii
- United Arab Emirates: https://lovi.care/skincare/ae/compare/clinique-vs-sk-ii