# Charlotte Tilbury vs Sesderma

Page: https://lovi.care/skincare/it/compare/charlotte-tilbury-vs-sesderma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Charlotte Tilbury is a British skincare brand founded in 2013 and owned by Puig since 2020.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Puig_(company)) [cosmeticsbusiness.com](https://cosmeticsbusiness.com/puig-to-fully-own-charlotte-tilbury-by-2031)

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

This page compares some of the most popular Charlotte Tilbury and Sesderma products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgfebf68129a).

### Popular Charlotte Tilbury vs Sesderma products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/it/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€46.00 at Notino](https://www.notino.it/sesderma/azelac-ru-siero-depigmentante/p-514983/)

#### Charlotte Tilbury

- [Charlotte's Magic Cream](https://lovi.care/skincare/it/p/charlotte-tilbury/charlotte-s-magic-cream/for/mature-skin) — Superior fit — [€181.72 at Amazon](https://www.amazon.it/dp/B0GM8SW85X?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Collagen Superfusion Facial Oil](https://lovi.care/skincare/it/p/charlotte-tilbury/collagen-superfusion-facial-oil/for/dry-sensitive-skin) — High fit
- [Magic Eye Rescue](https://lovi.care/skincare/it/p/charlotte-tilbury/magic-eye-rescue/for/dark-spots) — Average fit — [€91.54 at Amazon](https://www.amazon.it/dp/B0DGY5J7MV?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Charlotte Tilbury or Sesderma: which is better?

Charlotte Tilbury is the better choice for mature skin, where Charlotte's Magic Cream achieves a Superior Lovi fit. Reviewers frequently praise the brand for its hydrating moisturizers, though they note a high price point.

### What is the difference between Charlotte Tilbury and Sesderma?

Charlotte Tilbury's products on this page are completely fragrance-free and offer a Superior fit for mature skin, whereas Sesderma's Azelac RU [Serum](https://lovi.care/skincare/it/ingredients/serum) contains fragrance and achieves a High fit for acne-prone skin and skin with dark spots. Reviewers often note that Charlotte Tilbury provides hydrating moisturizers at a high price point.

### Which is more affordable, Charlotte Tilbury or Sesderma?

Reviewers note that Charlotte Tilbury has a high price point. The page facts do not mention pricing for Sesderma, so a direct comparison cannot be made.

### Which causes fewer breakouts, Charlotte Tilbury or Sesderma?

Sesderma has Azelac RU Serum, which helps with acne-prone skin at a High Lovi fit level, whereas Charlotte Tilbury's products on this page only reach an Average fit for acne-prone and oily acne-prone skin. [Azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid) is used to treat acne vulgaris.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Which brand has been around longer, Charlotte Tilbury or Sesderma?

Sesderma has been around longer, having been founded in Spain in 1989, whereas Charlotte Tilbury was founded in the United Kingdom in 2013.

### Do Charlotte Tilbury and Sesderma products contain fragrance?

Every product on the Charlotte Tilbury page lists no fragrance in its ingredients, whereas the Azelac RU Serum by Sesderma does contain fragrance.

### Which brand offers a facial oil, Charlotte Tilbury or Sesderma?

Charlotte Tilbury offers a facial oil in its range on this page, the [Collagen](https://lovi.care/skincare/it/ingredients/collagen) Superfusion Facial Oil, while Sesderma does not.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Polyglycerol Ester-Based Low Energy Nanoemulsions with Red Raspberry Seed Oil and Fruit Extracts: Formulation Development toward Effective In Vitro/In Vivo Bioperformance](https://pubmed.ncbi.nlm.nih.gov/33467701/) Raspberry seed oil · Nanomaterials, 2021
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015
- [Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil](https://pubmed.ncbi.nlm.nih.gov/31957954/) Avocado oil · Journal of Cosmetic Dermatology, 2020
- [Topical application of superoxide dismutase mediated by HIV-TAT peptide attenuates UVB-induced damages in human skin](https://pubmed.ncbi.nlm.nih.gov/27460952/) Superoxide dismutase · European Journal of Pharmaceutics and Biopharmaceutics, 2016
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis oil · Biomaterials Advances, 2022
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Melanogenesis effects of rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys on UVB-induced human epidermal melanocyte cells](https://pubmed.ncbi.nlm.nih.gov/32955075/) Hydrolyzed rice protein · Food & Function, 2020
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41319188/) Camellia oleifera seed oil · International Journal of Cosmetic Science, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter, African shea butter · Lasers in Medical Science, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025

## The brands

- British skincare: [Charlotte Tilbury](https://lovi.care/skincare/it/brands/charlotte-tilbury)
- Spanish skincare: [Sesderma](https://lovi.care/skincare/it/brands/sesderma)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/charlotte-tilbury-vs-sesderma
- United Kingdom: https://lovi.care/skincare/uk/compare/charlotte-tilbury-vs-sesderma
- Ireland: https://lovi.care/skincare/ie/compare/charlotte-tilbury-vs-sesderma
- Germany: https://lovi.care/skincare/de/compare/charlotte-tilbury-vs-sesderma
- France: https://lovi.care/skincare/fr/compare/charlotte-tilbury-vs-sesderma
- Italy: https://lovi.care/skincare/it/compare/charlotte-tilbury-vs-sesderma (this page)
- Netherlands: https://lovi.care/skincare/nl/compare/charlotte-tilbury-vs-sesderma
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