# CeraVe vs Sesderma

Page: https://lovi.care/skincare/it/compare/cerave-vs-sesderma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

CeraVe and Sesderma are trusted skincare brands that offer reliable daily routines and advanced treatments, respectively. The American brand, founded in 2005, is known for dependable moisturizers, gentle cleansers, targeted [serums](https://lovi.care/skincare/it/ingredients/serum), and protective sunscreens enriched with [hyaluronic acid](https://lovi.care/skincare/it/ingredients/hyaluronic-acid) and [glycerin](https://lovi.care/skincare/it/ingredients/glycerin), suiting mature and dry skin best. Meanwhile, the Spanish brand, founded in 1989, is beloved for advanced serums and meticulously engineered formulas that suit sensitive, hyperpigmented, and aging skin. While both deliver proven results through active compounds and botanical [extracts](https://lovi.care/skincare/it/ingredients/extract), the former relies on barrier-supporting ingredients like glycerin, whereas the latter specializes in synergistic treatments like the Azelac RU Serum.

CeraVe is an American skincare brand founded in 2005 and owned by L'Oréal since 2017.

[en.wikipedia.org](https://en.wikipedia.org/wiki/CeraVe) [happi.com](https://www.happi.com/exclusives/cerave-celebrates-20-years-in-business-with-birthday-tour/) [loreal-finance.com](https://www.loreal-finance.com/eng/news-release/loreal-finalizes-acquisition-cerave-acnefree-and-ambi) [cerave.com](https://www.cerave.com/about-cerave/developed-with-dermatologists)

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

This page compares some of the most popular CeraVe and Sesderma products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgf869d55c3b).

### Popular CeraVe vs Sesderma products

#### CeraVe

- [Moisturising Cream](https://lovi.care/skincare/it/p/cerave/moisturising-cream/for/dry-sensitive-skin) — Superior fit — [€12.89 at Amazon](https://www.amazon.it/dp/B07CH9XWHR?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Hydrating Facial Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [€9.19 at Amazon](https://www.amazon.it/dp/B07C5R51Q9?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Foaming Facial Cleanser](https://lovi.care/skincare/it/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€24.75 at Amazon](https://www.amazon.it/dp/B0CRSJ46YD?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Daily Moisturizing Lotion](https://lovi.care/skincare/it/p/cerave/daily-moisturizing-lotion/for/dry-skin) — Superior fit — [€10.19 at Amazon](https://www.amazon.it/dp/B07CG2TD9F?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Resurfacing Retinol Serum](https://lovi.care/skincare/it/p/cerave/resurfacing-retinol-serum/for/dark-spots) — High fit — [€21.60 at Notino](https://www.notino.it/cerave/blemish-control-siero-attivo-con-retinolo/p-16142856/)
- [Healing Ointment](https://lovi.care/skincare/it/p/cerave/healing-ointment/for/dry-skin) — High fit
- [Renewing SA Cleanser](https://lovi.care/skincare/it/p/cerave/renewing-sa-cleanser/for/oily-acne-prone-skin) — High fit — [€16.89 at Amazon](https://www.amazon.it/dp/B00U1YCRD8?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [PM Facial Moisturizing Lotion](https://lovi.care/skincare/it/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [€14.20 at Amazon](https://www.amazon.it/dp/B07C5XYT19?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/it/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€46.00 at Notino](https://www.notino.it/sesderma/azelac-ru-siero-depigmentante/p-514983/)

### CeraVe vs Sesderma [serums](https://lovi.care/skincare/it/ingredients/serum) and treatments

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/it/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€46.00 at Notino](https://www.notino.it/sesderma/azelac-ru-siero-depigmentante/p-514983/)

#### CeraVe

- [Resurfacing Retinol Serum](https://lovi.care/skincare/it/p/cerave/resurfacing-retinol-serum/for/dark-spots) — High fit — [€21.60 at Notino](https://www.notino.it/cerave/blemish-control-siero-attivo-con-retinolo/p-16142856/)
- [Skin Renewing Vitamin C Serum](https://lovi.care/skincare/it/p/cerave/skin-renewing-vitamin-c-serum/for/acne-prone-skin) — High fit — [€19.99 at Amazon](https://www.amazon.it/dp/B0FHPZ4KGH?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Skin Renewing Retinol Serum](https://lovi.care/skincare/it/p/cerave/skin-renewing-retinol-serum/for/dark-spots) — Average fit — [€25.41 at Amazon](https://www.amazon.it/dp/B0FHPRRNX8?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- [Skin Renewing Nightly Exfoliating Treatment](https://lovi.care/skincare/it/p/cerave/skin-renewing-nightly-exfoliating-treatment/for/acne-prone-skin) — High fit
- [Acne Control Gel](https://lovi.care/skincare/it/p/cerave/acne-control-gel/for/oily-acne-prone-skin) — Superior fit — [€14.70 at Notino](https://www.notino.it/cerave/blemish-control-gel-gel-anti-imperfezioni/p-16139491/)

## Questions and answers

### CeraVe or Sesderma: which is better?

CeraVe has a much broader lineup of fragrance-free products on this page and fits mature, dry, and acne-prone skin best. Sesderma offers fewer options here, with only Azelac RU [Serum](https://lovi.care/skincare/it/ingredients/serum) listed, and its formula includes fragrance.

### What is the difference between CeraVe and Sesderma?

CeraVe offers a broad range of fragrance-free cleansers, moisturizers, and serums with a Superior or High Lovi fit for mature, dry, and acne-prone skin, while Sesderma features just one serum with fragrance listed on this page.

### Which is more affordable, CeraVe or Sesderma?

This page does not provide pricing or affordability information for either CeraVe or Sesderma.

### Which causes fewer breakouts, CeraVe or Sesderma?

CeraVe helps provide gentle, fragrance-free products on this page with high-fit options for acne-prone skin, whereas Sesderma lists fewer options and includes fragrance, which may sometimes irritate sensitive or acne-prone skin.

### How do the founding years and countries of origin compare between CeraVe and Sesderma?

CeraVe was founded in 2005 in the United States, whereas Sesderma was founded in 1989 in Spain.

### Which brand offers a greater variety of products for dry skin according to the page?

CeraVe offers a greater variety of products for dry skin on this page, including multiple cleansers and moisturizers with High to Superior Lovi fit levels for dry skin. Sesderma features only a single serum on the page, which has a Low fit level for dry skin.

### Do both CeraVe and Sesderma products include fragrance-free options?

Yes, CeraVe offers fragrance-free options across the products on this page, while Sesderma does not list any fragrance-free options for its products.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Peptide complex · International Journal of Cosmetic Science, 2005
- [Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/18489348/) Phytosphingosine · International Journal of Cosmetic Science, 2007
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides, Ceraplex 5-ceramide blend · Scientific Reports, 2022
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np, Ceramide eop · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Licorice root extract · Experimental Dermatology, 2015
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Encapsulation and controlled release of retinol from silicone particles for topical delivery](https://pubmed.ncbi.nlm.nih.gov/29604311/) Encapsulated retinol · Journal of Controlled Release, 2018
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Vitamin b5 · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) 3 essential ceramides, Ceramide np · Skin Pharmacology and Physiology, 2022
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study](https://pubmed.ncbi.nlm.nih.gov/36698447/) Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids](https://pubmed.ncbi.nlm.nih.gov/12482041/) Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study](https://pubmed.ncbi.nlm.nih.gov/40682399/) 3 essential ceramides · Journal of Cosmetic Dermatology, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride, Capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study](https://pubmed.ncbi.nlm.nih.gov/41487026/) Zinc gluconate · Journal of Cosmetic Dermatology, 2026
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octocrylene · Archives of Dermatological Research, 2024
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Saccharide isomerate · Lasers in Medical Science, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Tripeptide-1, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu](https://pubmed.ncbi.nlm.nih.gov/42573538/) Tripeptide-1 · Skin Research and Technology, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Octisalate · Journal of Drugs in Dermatology, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Hectorite clay · Journal of Cosmetic Dermatology, 2025

## The brands

- American skincare: [CeraVe](https://lovi.care/skincare/it/brands/cerave)
- Spanish skincare: [Sesderma](https://lovi.care/skincare/it/brands/sesderma)

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- [CeraVe vs Some By Mi](https://lovi.care/skincare/it/compare/cerave-vs-some-by-mi)
- [CeraVe vs Torriden](https://lovi.care/skincare/it/compare/cerave-vs-torriden)
- [CeraVe vs celimax](https://lovi.care/skincare/it/compare/cerave-vs-celimax)
- [CeraVe vs Purito](https://lovi.care/skincare/it/compare/cerave-vs-purito)
- [CeraVe vs Cetaphil](https://lovi.care/skincare/it/compare/cerave-vs-cetaphil)
- [CeraVe vs Paula's Choice](https://lovi.care/skincare/it/compare/cerave-vs-paula-s-choice)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

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- Spain: https://lovi.care/skincare/es/compare/cerave-vs-sesderma
- Canada: https://lovi.care/skincare/ca/compare/cerave-vs-sesderma
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