# Sesderma skincare

Page: https://lovi.care/skincare/it/brands/sesderma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

Sesderma is beloved for its advanced [serums](https://lovi.care/skincare/it/ingredients/serum) and meticulously engineered formulas. Its products suit sensitive, hyperpigmented, and aging skin types best. The standout products for particular concerns include the Azelac RU Serum for acne-prone skin. Its botanical [extracts](https://lovi.care/skincare/it/ingredients/extract) and active compounds work synergistically to refine skin texture and promote a radiant complexion.

This page covers some of the most popular Sesderma products; for the whole Sesderma range, with a fit score for every product, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=brand&af_sub3=selection_note&af_sub4=pgc02906d8a1).

### Sesderma [serums](https://lovi.care/skincare/it/ingredients/serum) and treatments

#### Serums and treatments

- [Azelac RU Serum](https://lovi.care/skincare/it/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€46.00 at Notino](https://www.notino.it/sesderma/azelac-ru-siero-depigmentante/p-514983/)

## Questions and answers

### Is Sesderma worth it?

Sesderma rates Superior for dry, oily, sensitive, combination, and acne-prone skin, making it a strong choice for these skin types. The Sesderma products on this page include fragrance.

### What are Sesderma's best products?

Sesderma offers the Azelac RU [Serum](https://lovi.care/skincare/it/ingredients/serum), which Lovi rates High for acne-prone skin, dark spots, and combination skin. Lovi rates the Sesderma-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Does Sesderma cause breakouts?

No, Azelac RU Serum helps manage blemishes, and Lovi rates acne-prone skin High for this product. Sesderma-focused routines also rate Superior for acne-prone skin.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Is Sesderma fragrance-free?

No, the Sesderma products on this page contain fragrance, as seen with Azelac RU Serum.

### What are the key ingredients in Sesderma products?

Sesderma uses [azelaic acid](https://lovi.care/skincare/it/ingredients/azelaic-acid) and [4-butylresorcinol](https://lovi.care/skincare/it/ingredients/butylresorcinol) in its Azelac RU Serum to target dark spots and acne-prone areas. Azelaic acid helps manage blemishes, while 4-butylresorcinol reduces skin pigmentation.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### How do I build a Sesderma skincare routine?

To build a Sesderma skincare routine, you can use the Azelac RU Serum, which helps care for various skin concerns. Lovi rates the Sesderma-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.

### Where can I buy Sesderma, and how much does it cost?

Sesderma products are available through stores in Italy. Prices on this page range from €46.00 to €46.00.

### What are good alternatives to Sesderma?

Good alternatives to Sesderma include ISDIN, Heliocare, Theramid, Mesoestetic, Endocare, and ISDIN Isdinceutics. These similar brands also have pages on Lovi.

### Sesderma vs ISDIN: which is better?

Both Sesderma and ISDIN offer great options, as Lovi rates a Sesderma-focused routine as Superior for dry, oily, sensitive, combination, and acne-prone skin, matching the Superior fit levels of an ISDIN-focused routine across all these skin types.

### Who owns Sesderma, and where is it from?

Sesderma is a Spanish brand founded in 1989, owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

### Is Sesderma cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Sesderma as cruelty-free.

## Research behind Sesderma's key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024

## Similar brands

- Spanish skincare: [ISDIN](https://lovi.care/skincare/it/brands/isdin)
- Spanish skincare: [Heliocare](https://lovi.care/skincare/it/brands/heliocare)
- Spanish skincare: [Theramid](https://lovi.care/skincare/it/brands/theramid)
- Spanish skincare: [Mesoestetic](https://lovi.care/skincare/it/brands/mesoestetic)
- Spanish skincare: [Endocare](https://lovi.care/skincare/it/brands/endocare)
- Spanish skincare: [ISDIN Isdinceutics](https://lovi.care/skincare/it/brands/isdin-isdinceutics)
- Spanish skincare: [Natura Bissé](https://lovi.care/skincare/it/brands/natura-bisse)
- Spanish skincare: [Noche Y Dia](https://lovi.care/skincare/it/brands/noche-y-dia)

## Compare Sesderma

- [SKIN1004 vs Sesderma](https://lovi.care/skincare/it/compare/skin1004-vs-sesderma)
- [Anua vs Sesderma](https://lovi.care/skincare/it/compare/anua-vs-sesderma)
- [Medicube vs Sesderma](https://lovi.care/skincare/it/compare/medicube-vs-sesderma)
- [The Ordinary vs Sesderma](https://lovi.care/skincare/it/compare/the-ordinary-vs-sesderma)
- [Beauty of Joseon vs Sesderma](https://lovi.care/skincare/it/compare/beauty-of-joseon-vs-sesderma)
- [COSRX vs Sesderma](https://lovi.care/skincare/it/compare/cosrx-vs-sesderma)
- [CeraVe vs Sesderma](https://lovi.care/skincare/it/compare/cerave-vs-sesderma)
- [La Roche-Posay vs Sesderma](https://lovi.care/skincare/it/compare/la-roche-posay-vs-sesderma)
- [Dr. Althea vs Sesderma](https://lovi.care/skincare/it/compare/dr-althea-vs-sesderma)
- [Some By Mi vs Sesderma](https://lovi.care/skincare/it/compare/some-by-mi-vs-sesderma)
- [Torriden vs Sesderma](https://lovi.care/skincare/it/compare/torriden-vs-sesderma)
- [celimax vs Sesderma](https://lovi.care/skincare/it/compare/celimax-vs-sesderma)
- [Purito vs Sesderma](https://lovi.care/skincare/it/compare/purito-vs-sesderma)
- [Cetaphil vs Sesderma](https://lovi.care/skincare/it/compare/cetaphil-vs-sesderma)
- [Paula's Choice vs Sesderma](https://lovi.care/skincare/it/compare/paula-s-choice-vs-sesderma)
- [Neutrogena vs Sesderma](https://lovi.care/skincare/it/compare/neutrogena-vs-sesderma)
- [Kiehl's vs Sesderma](https://lovi.care/skincare/it/compare/kiehl-s-vs-sesderma)
- [Caudalie vs Sesderma](https://lovi.care/skincare/it/compare/caudalie-vs-sesderma)
- [Dermalogica vs Sesderma](https://lovi.care/skincare/it/compare/dermalogica-vs-sesderma)
- [Good Molecules vs Sesderma](https://lovi.care/skincare/it/compare/good-molecules-vs-sesderma)

## Popular brands

- Korean skincare: [SKIN1004](https://lovi.care/skincare/it/brands/skin1004)
- Korean skincare: [Anua](https://lovi.care/skincare/it/brands/anua)
- Korean skincare: [Medicube](https://lovi.care/skincare/it/brands/medicube)
- Canadian skincare: [The Ordinary](https://lovi.care/skincare/it/brands/the-ordinary)
- Korean skincare: [Beauty of Joseon](https://lovi.care/skincare/it/brands/beauty-of-joseon)
- Korean skincare: [COSRX](https://lovi.care/skincare/it/brands/cosrx)
- American skincare: [CeraVe](https://lovi.care/skincare/it/brands/cerave)
- French skincare: [La Roche-Posay](https://lovi.care/skincare/it/brands/la-roche-posay)
- Korean skincare: [Dr. Althea](https://lovi.care/skincare/it/brands/dr-althea)
- Korean skincare: [Some By Mi](https://lovi.care/skincare/it/brands/some-by-mi)
- Korean skincare: [Torriden](https://lovi.care/skincare/it/brands/torriden)
- Korean skincare: [celimax](https://lovi.care/skincare/it/brands/celimax)
- Korean skincare: [Purito](https://lovi.care/skincare/it/brands/purito)
- Korean skincare: [ROUND LAB](https://lovi.care/skincare/it/brands/round-lab)
- American skincare: [Cetaphil](https://lovi.care/skincare/it/brands/cetaphil)
- American skincare: [Paula's Choice](https://lovi.care/skincare/it/brands/paula-s-choice)
- American skincare: [Neutrogena](https://lovi.care/skincare/it/brands/neutrogena)
- Korean skincare: [AXIS-Y](https://lovi.care/skincare/it/brands/axis-y)
- American skincare: [Kiehl's](https://lovi.care/skincare/it/brands/kiehl-s)
- Korean skincare: [d'Alba](https://lovi.care/skincare/it/brands/d-alba)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi rates every product from its full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind these ratings: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/brands/sesderma
- United Kingdom: https://lovi.care/skincare/uk/brands/sesderma
- Ireland: https://lovi.care/skincare/ie/brands/sesderma
- Germany: https://lovi.care/skincare/de/brands/sesderma
- France: https://lovi.care/skincare/fr/brands/sesderma
- Italy: https://lovi.care/skincare/it/brands/sesderma (this page)
- Netherlands: https://lovi.care/skincare/nl/brands/sesderma
- Spain: https://lovi.care/skincare/es/brands/sesderma
- Canada: https://lovi.care/skincare/ca/brands/sesderma
- Australia: https://lovi.care/skincare/au/brands/sesderma
- Singapore: https://lovi.care/skincare/sg/brands/sesderma
- Saudi Arabia: https://lovi.care/skincare/sa/brands/sesderma
- United Arab Emirates: https://lovi.care/skincare/ae/brands/sesderma