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Superoxide dismutase and palmitoyl pentapeptide-4

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Superoxide dismutase and palmitoyl pentapeptide-4: keep them apart

Keep them apart

Use them at different times of day, applying superoxide dismutase first and palmitoyl pentapeptide-4 later, to prevent the enzyme from breaking down the peptide. Superoxide dismutase can act like a pair of scissors, chopping up the peptide and stopping it from smoothing wrinkles. The shopper can separate them by using one in the morning and the other at night.

Superoxide dismutase products

Palmitoyl pentapeptide-4 products

Questions and answers

Can you use superoxide dismutase and palmitoyl pentapeptide-4 together?

Keep superoxide dismutase and palmitoyl pentapeptide-4 apart because enzymes can degrade peptide bonds and render the peptides inactive. Avoid combining enzymatic ingredients with peptides in the same routine.

Which goes first, superoxide dismutase or palmitoyl pentapeptide-4?

Keep superoxide dismutase and palmitoyl pentapeptide-4 apart because enzymes like superoxide dismutase can degrade peptides.

Are superoxide dismutase and palmitoyl pentapeptide-4 good for sensitive skin?

Keep superoxide dismutase and palmitoyl pentapeptide-4 apart in your routine because enzymes can break down peptides and make them inactive. Both ingredients individually help improve skin signs, but they should not be combined.

Research on superoxide dismutase and palmitoyl pentapeptide-4

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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