# Superoxide dismutase and copper peptide

Page: https://lovi.care/skincare/ingredients/superoxide-dismutase-and-copper-peptide

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Keep them apart

Use them at different times of day, applying [copper peptide](https://lovi.care/skincare/ingredients/copper-peptide) in the morning and [superoxide dismutase](https://lovi.care/skincare/ingredients/superoxide-dismutase) at night. Enzymes can break down delicate peptides and stop them from working properly. You can space them out into separate routines or switch to a gentler formula.

- [All about superoxide dismutase](https://lovi.care/skincare/ingredients/superoxide-dismutase)
- [All about copper peptide](https://lovi.care/skincare/ingredients/copper-peptide)

### [Superoxide dismutase](https://lovi.care/skincare/ingredients/superoxide-dismutase) products

- [iS Clinical Reparative Moisture Emulsion](https://lovi.care/skincare/p/is-clinical/reparative-moisture-emulsion/for/dry-skin) — High fit
- [U Beauty Resurfacing Compound](https://lovi.care/skincare/p/u-beauty/resurfacing-compound/for/dark-spots) — High fit — [$148.00 at Amazon](https://www.amazon.com/dp/B089B9MZ1H?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Skinbetter Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/p/skinbetter-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin) — High fit
- [Skin Better Science Alto Advanced Defense and Repair Serum](https://lovi.care/skincare/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-skin) — High fit
- [Skinbetter Science Alto Defense Serum](https://lovi.care/skincare/p/skinbetter-science/alto-defense-serum/for/dark-spots) — High fit
- [NIOD Modulating Glucosides](https://lovi.care/skincare/p/niod/modulating-glucosides/for/mature-skin) — High fit
- [Charlotte Tilbury Magic Eye Rescue](https://lovi.care/skincare/p/charlotte-tilbury/magic-eye-rescue/for/dark-spots) — Average fit — [$65.00 at Amazon](https://www.amazon.com/dp/B0FGG3LFKK?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — [$53.00 at Amazon](https://www.amazon.com/dp/B00EEGEI7C?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Image Skincare Vital C Hydrating Enzyme Masque](https://lovi.care/skincare/p/image-skincare/vital-c-hydrating-enzyme-masque/for/mature-skin) — High fit
- [NIOD Superoxide Dismutase Saccharide Mist](https://lovi.care/skincare/p/niod/superoxide-dismutase-saccharide-mist/for/dry-sensitive-skin) — Average fit
- [Dr. Dennis Gross C + Collagen Biocellulose Brightening Treatment Mask](https://lovi.care/skincare/p/dr-dennis-gross/c-collagen-biocellulose-brightening-treatment-mask/for/mature-skin) — High fit — [$46.00 at Amazon](https://www.amazon.com/dp/B0BS4FVQZ4?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

### [Copper peptide](https://lovi.care/skincare/ingredients/copper-peptide) products

- [The Ordinary Multi-Peptide + Copper Peptides 1% Serum](https://lovi.care/skincare/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin) — High fit — [$32.00 at Amazon](https://www.amazon.com/dp/B0C9DXGXZ3?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Biossance Squalane + Copper Peptide Rapid Plumping Serum](https://lovi.care/skincare/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/dry-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B09PLKS55F?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Good Molecules Super Peptide Serum](https://lovi.care/skincare/p/good-molecules/super-peptide-serum/for/mature-skin) — High fit — [$12.00 at Amazon](https://www.amazon.com/dp/B091MTKS35?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Allies of Skin Copper Tripeptide & Ectoin Advanced Repair Serum](https://lovi.care/skincare/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/oily-acne-prone-skin) — High fit — [$199.00 at Amazon](https://www.amazon.com/dp/B0DDXZB2BJ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [COSRX Advanced Snail Peptide Eye Cream](https://lovi.care/skincare/p/cosrx/advanced-snail-peptide-eye-cream/for/dark-spots) — High fit — [$20.90 at Amazon](https://www.amazon.com/dp/B07ZRF416W?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Hero Cosmetics Rescue Balm](https://lovi.care/skincare/p/hero-cosmetics/rescue-balm/for/mature-skin) — High fit — [$12.88 at Amazon](https://www.amazon.com/dp/B0FG5QGHYL?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Mederma PM Intensive Overnight Scar Cream](https://lovi.care/skincare/p/mederma/pm-intensive-overnight-scar-cream/for/sensitive-skin) — High fit
- [Perricone MD Cold Plasma Plus+](https://lovi.care/skincare/p/perricone-md/cold-plasma-plus/for/mature-skin) — Average fit — [$105.00 at Amazon](https://www.amazon.com/dp/B0BQ8LPM7S?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — [$19.90 at Amazon](https://www.amazon.com/dp/B08RYMSLPG?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [MISSHA Time Revolution Night Repair Ampoule](https://lovi.care/skincare/p/missha/time-revolution-night-repair-ampoule/for/dark-spots) — High fit
- [Peach & Lily Copper Peptide Pro Firming Serum](https://lovi.care/skincare/p/peach-and-lily/copper-peptide-pro-firming-serum/for/mature-skin) — High fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0CRH3PH72?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Theramid Copper Peptide](https://lovi.care/skincare/p/theramid/copper-peptide/for/oily-skin) — High fit

## Questions and answers

### Can you use superoxide dismutase and copper peptide together?

No, you should keep [superoxide dismutase](https://lovi.care/skincare/ingredients/superoxide-dismutase) and [copper peptide](https://lovi.care/skincare/ingredients/copper-peptide) apart in your routine because enzymes can degrade peptides and render them inactive.

### Which goes first, superoxide dismutase or copper peptide?

Keep superoxide dismutase and copper peptide apart in your routine because mixing them may degrade peptide bonds and render the actives inactive.

### Are superoxide dismutase and copper peptide good for sensitive skin?

Superoxide dismutase and copper peptide should be kept apart in your routine because enzymes can degrade peptide bonds and render them inactive.

## Research on superoxide dismutase and copper peptide

- [Topical application of superoxide dismutase mediated by HIV-TAT peptide attenuates UVB-induced damages in human skin](https://pubmed.ncbi.nlm.nih.gov/27460952/) Superoxide dismutase · European Journal of Pharmaceutics and Biopharmaceutics, 2016
- [Use of the synthetic superoxide dismutase/catalase mimetic EUK-134 to compensate for seasonal antioxidant deficiency by reducing pre-existing lipid peroxides at the human skin surface](https://pubmed.ncbi.nlm.nih.gov/18492138/) Superoxide dismutase · International Journal of Cosmetic Science, 2004
- [Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin](https://pubmed.ncbi.nlm.nih.gov/16847171/) Copper peptide · Archives of Facial Plastic Surgery, 2006
- [Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu](https://pubmed.ncbi.nlm.nih.gov/42573538/) Copper peptide · Skin Research and Technology, 2026

## Other combinations

- Keep them apart: [Adapalene and copper peptide](https://lovi.care/skincare/ingredients/adapalene-and-copper-peptide)
- Keep them apart: [Granactive retinoid and copper peptide](https://lovi.care/skincare/ingredients/granactive-retinoid-and-copper-peptide)
- Keep them apart: [Hydroxypinacolone retinoate and copper peptide](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-copper-peptide)
- Keep them apart: [Pro-retinol and copper peptide](https://lovi.care/skincare/ingredients/pro-retinol-and-copper-peptide)
- Keep them apart: [Retinal and copper peptide](https://lovi.care/skincare/ingredients/retinal-and-copper-peptide)
- Keep them apart: [Retinoid blend and copper peptide](https://lovi.care/skincare/ingredients/retinoid-blend-and-copper-peptide)
- Depends on the strength: [Retinol and copper peptide](https://lovi.care/skincare/ingredients/retinol-and-copper-peptide)
- Keep them apart: [Tretinoin and copper peptide](https://lovi.care/skincare/ingredients/tretinoin-and-copper-peptide)
- Keep them apart: [Vitamin A and copper peptide](https://lovi.care/skincare/ingredients/vitamin-a-and-copper-peptide)
- Work well together: [Liposome and copper peptide](https://lovi.care/skincare/ingredients/liposome-and-copper-peptide)
- Work well together: [Microcapsule and copper peptide](https://lovi.care/skincare/ingredients/microcapsule-and-copper-peptide)
- Keep them apart: [Vitamin C and copper peptide](https://lovi.care/skincare/ingredients/vitamin-c-and-copper-peptide)
- Work well together: [Betaine and copper peptide](https://lovi.care/skincare/ingredients/betaine-and-copper-peptide)
- Work well together: [Glycerin and copper peptide](https://lovi.care/skincare/ingredients/glycerin-and-copper-peptide)
- Work well together: [Hyaluronic acid and copper peptide](https://lovi.care/skincare/ingredients/hyaluronic-acid-and-copper-peptide)
- Depends on the strength: [Niacinamide and copper peptide](https://lovi.care/skincare/ingredients/niacinamide-and-copper-peptide)
- Work well together: [Panthenol and copper peptide](https://lovi.care/skincare/ingredients/panthenol-and-copper-peptide)
- Work well together: [Bakuchiol and copper peptide](https://lovi.care/skincare/ingredients/bakuchiol-and-copper-peptide)
- Work well together: [Arginine and copper peptide](https://lovi.care/skincare/ingredients/arginine-and-copper-peptide)
- Work well together: [Copper peptide and GABA](https://lovi.care/skincare/ingredients/copper-peptide-and-gaba)
- Work well together: [Silk amino acids and copper peptide](https://lovi.care/skincare/ingredients/silk-amino-acids-and-copper-peptide)
- Work well together: [Taurine and copper peptide](https://lovi.care/skincare/ingredients/taurine-and-copper-peptide)
- Work well together: [Copper peptide and theanine](https://lovi.care/skincare/ingredients/copper-peptide-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and copper peptide](https://lovi.care/skincare/ingredients/aha-blend-glycolic-and-citric-acids-and-copper-peptide)
- Keep them apart: [Copper peptide and citric acid](https://lovi.care/skincare/ingredients/copper-peptide-and-citric-acid)
- Keep them apart: [Glycolic acid and copper peptide](https://lovi.care/skincare/ingredients/glycolic-acid-and-copper-peptide)
- Keep them apart: [Lactic acid and copper peptide](https://lovi.care/skincare/ingredients/lactic-acid-and-copper-peptide)
- Keep them apart: [Mandelic acid and copper peptide](https://lovi.care/skincare/ingredients/mandelic-acid-and-copper-peptide)
- Work well together: [Coenzyme Q10 and copper peptide](https://lovi.care/skincare/ingredients/coenzyme-q10-and-copper-peptide)
- Work well together: [Green tea and copper peptide](https://lovi.care/skincare/ingredients/green-tea-and-copper-peptide)
- Work well together: [Vitamin E and copper peptide](https://lovi.care/skincare/ingredients/vitamin-e-and-copper-peptide)
- Work well together: [Copper peptide and beta-sitosterol](https://lovi.care/skincare/ingredients/copper-peptide-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and copper peptide](https://lovi.care/skincare/ingredients/ceramide-building-complex-and-copper-peptide)
- Work well together: [Cholesterol and copper peptide](https://lovi.care/skincare/ingredients/cholesterol-and-copper-peptide)
- Work well together: [Phytosphingosine and copper peptide](https://lovi.care/skincare/ingredients/phytosphingosine-and-copper-peptide)
- Work well together: [Phytosterol and copper peptide](https://lovi.care/skincare/ingredients/phytosterol-and-copper-peptide)
- Work well together: [Copper peptide and squalene](https://lovi.care/skincare/ingredients/copper-peptide-and-squalene)
- Work well together: [Copper peptide and tri-ceramide complex](https://lovi.care/skincare/ingredients/copper-peptide-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and copper peptide](https://lovi.care/skincare/ingredients/salicylic-acid-and-copper-peptide)
- Keep them apart: [Copper peptide and baking soda](https://lovi.care/skincare/ingredients/copper-peptide-and-baking-soda)
- Keep them apart: [Bleach and copper peptide](https://lovi.care/skincare/ingredients/bleach-and-copper-peptide)
- Keep them apart: [Potassium hydroxide and copper peptide](https://lovi.care/skincare/ingredients/potassium-hydroxide-and-copper-peptide)
- Keep them apart: [Copper peptide and behenyl alcohol](https://lovi.care/skincare/ingredients/copper-peptide-and-behenyl-alcohol)
- Keep them apart: [Copper peptide and isopropyl alcohol](https://lovi.care/skincare/ingredients/copper-peptide-and-isopropyl-alcohol)
- Keep them apart: [Polyvinyl alcohol and copper peptide](https://lovi.care/skincare/ingredients/polyvinyl-alcohol-and-copper-peptide)
- Keep them apart: [Copper and copper peptide](https://lovi.care/skincare/ingredients/copper-and-copper-peptide)
- Keep them apart: [Benzoyl peroxide and copper peptide](https://lovi.care/skincare/ingredients/benzoyl-peroxide-and-copper-peptide)
- Keep them apart: [Magnesium and copper peptide](https://lovi.care/skincare/ingredients/magnesium-and-copper-peptide)
- Keep them apart: [Zinc and copper peptide](https://lovi.care/skincare/ingredients/zinc-and-copper-peptide)
- Keep them apart: [Zinc sulfate and copper peptide](https://lovi.care/skincare/ingredients/zinc-sulfate-and-copper-peptide)
- Keep them apart: [Azelaic acid and copper peptide](https://lovi.care/skincare/ingredients/azelaic-acid-and-copper-peptide)
- Keep them apart: [Acetyl hexapeptide-3 and superoxide dismutase](https://lovi.care/skincare/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase)
- Keep them apart: [Bio-placenta peptides and superoxide dismutase](https://lovi.care/skincare/ingredients/bio-placenta-peptides-and-superoxide-dismutase)
- Keep them apart: [Superoxide dismutase and collagen peptide](https://lovi.care/skincare/ingredients/superoxide-dismutase-and-collagen-peptide)
- Keep them apart: [Copper peptide and protease](https://lovi.care/skincare/ingredients/copper-peptide-and-protease)
- Keep them apart: [Hexapeptide and superoxide dismutase](https://lovi.care/skincare/ingredients/hexapeptide-and-superoxide-dismutase)
- Keep them apart: [Superoxide dismutase and hexapeptide-9](https://lovi.care/skincare/ingredients/superoxide-dismutase-and-hexapeptide-9)
- Keep them apart: [Superoxide dismutase and palmitoyl pentapeptide-4](https://lovi.care/skincare/ingredients/superoxide-dismutase-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Superoxide dismutase and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/superoxide-dismutase-and-palmitoyl-tripeptide-1)
- Keep them apart: [Superoxide dismutase and peptide-rich plasma](https://lovi.care/skincare/ingredients/superoxide-dismutase-and-peptide-rich-plasma)
- Keep them apart: [Superoxide dismutase and triple peptide blend](https://lovi.care/skincare/ingredients/superoxide-dismutase-and-triple-peptide-blend)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/superoxide-dismutase-and-copper-peptide (this page)
- United Kingdom: https://lovi.care/skincare/uk/ingredients/superoxide-dismutase-and-copper-peptide
- Ireland: https://lovi.care/skincare/ie/ingredients/superoxide-dismutase-and-copper-peptide
- Germany: https://lovi.care/skincare/de/ingredients/superoxide-dismutase-and-copper-peptide
- France: https://lovi.care/skincare/fr/ingredients/superoxide-dismutase-and-copper-peptide
- Italy: https://lovi.care/skincare/it/ingredients/superoxide-dismutase-and-copper-peptide
- Netherlands: https://lovi.care/skincare/nl/ingredients/superoxide-dismutase-and-copper-peptide
- Spain: https://lovi.care/skincare/es/ingredients/superoxide-dismutase-and-copper-peptide
- Canada: https://lovi.care/skincare/ca/ingredients/superoxide-dismutase-and-copper-peptide
- Australia: https://lovi.care/skincare/au/ingredients/superoxide-dismutase-and-copper-peptide
- Singapore: https://lovi.care/skincare/sg/ingredients/superoxide-dismutase-and-copper-peptide
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/superoxide-dismutase-and-copper-peptide
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/superoxide-dismutase-and-copper-peptide