# Niacinamide and zinc oxide

Page: https://lovi.care/skincare/ingredients/niacinamide-and-zinc-oxide

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Work well together

Use them together in the same routine, applying [niacinamide](https://lovi.care/skincare/ingredients/niacinamide) first and [zinc oxide](https://lovi.care/skincare/ingredients/zinc-oxide) second to boost blemish control. Niacinamide and zinc oxide team up to calm redness and keep oiliness under control. If your skin feels sensitive, try using them on alternate days or switch to a gentler formula.

- [All about niacinamide](https://lovi.care/skincare/ingredients/niacinamide)
- [All about zinc oxide](https://lovi.care/skincare/ingredients/zinc-oxide)

### [Niacinamide](https://lovi.care/skincare/ingredients/niacinamide) products

- [La Roche-Posay Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit — [$24.99 at Amazon](https://www.amazon.com/dp/B01N9SPQHQ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [$15.97 at Amazon](https://www.amazon.com/dp/B01N1LL62W?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Cetaphil Gentle Skin Cleanser](https://lovi.care/skincare/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [$13.44 at Amazon](https://www.amazon.com/dp/B099N3NM61?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [$19.99 at Amazon](https://www.amazon.com/dp/B01N7T7JKJ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Dr. Althea 345 Relief Cream](https://lovi.care/skincare/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [$27.00 at Amazon](https://www.amazon.com/dp/B0FKGJYFC8?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — [$19.00 at Amazon](https://www.amazon.com/dp/B0B2RM68G2?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [$23.54 at Amazon](https://www.amazon.com/dp/B007M81B4M?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [CeraVe Resurfacing Retinol Serum](https://lovi.care/skincare/p/cerave/resurfacing-retinol-serum/for/dark-spots) — High fit — [$16.44 at Amazon](https://www.amazon.com/dp/B07VWSN95S?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [$13.62 at Amazon](https://www.amazon.com/dp/B00365DABC?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube PDRN Pink Peptide Serum](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [$18.90 at Amazon](https://www.amazon.com/dp/B0DBF65JYY?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [CeraVe Renewing SA Cleanser](https://lovi.care/skincare/p/cerave/renewing-sa-cleanser/for/oily-acne-prone-skin) — High fit — [$12.37 at Amazon](https://www.amazon.com/dp/B00U1YCRD8?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube Collagen Jelly Cream](https://lovi.care/skincare/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [$14.90 at Amazon](https://www.amazon.com/dp/B0DGPSZVW3?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

### [Zinc oxide](https://lovi.care/skincare/ingredients/zinc-oxide) products

- [Mario Badescu Drying Lotion](https://lovi.care/skincare/p/mario-badescu/drying-lotion/for/oily-skin) — High fit — [$18.00 at Amazon](https://www.amazon.com/dp/B0017SWIU4?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Avène Cicalfate+ Restorative Protective Cream](https://lovi.care/skincare/p/avene/cicalfate-restorative-protective-cream/for/dry-skin) — High fit — [$40.00 at Amazon](https://www.amazon.com/dp/B07YBCJBG2?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Calmoseptine Ointment](https://lovi.care/skincare/p/calmoseptine/ointment/for/dry-skin) — Warning fit
- [Desitin Maximum Strength Diaper Rash Paste](https://lovi.care/skincare/p/desitin/maximum-strength-diaper-rash-paste/for/dry-skin) — Average fit
- [House of HUR Weightless Sun Fluid](https://lovi.care/skincare/p/house-of-hur/weightless-sun-fluid/for/dry-sensitive-skin) — Superior fit
- [Supergoop! Mineral Mattescreen SPF 40](https://lovi.care/skincare/p/supergoop/mineral-mattescreen-spf-40/for/acne-prone-skin) — High fit — [$40.00 at Amazon](https://www.amazon.com/dp/B09J9X2NNR?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Colorescience Total Protection No-Show Mineral Sunscreen SPF 50](https://lovi.care/skincare/p/colorescience/total-protection-no-show-mineral-sunscreen-spf-50/for/dry-sensitive-skin) — Superior fit — [$48.00 at Amazon](https://www.amazon.com/dp/B0C767Y45N?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Blue Lizard Sensitive Mineral Sunscreen SPF 50+](https://lovi.care/skincare/p/blue-lizard/sensitive-mineral-sunscreen-spf-50/for/sensitive-skin) — Superior fit — [$12.91 at Amazon](https://www.amazon.com/dp/B084ZP848Y?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [ISDIN Eryfotona Actinica](https://lovi.care/skincare/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [$46.00 at Amazon](https://www.amazon.com/dp/B0CV8716J5?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Canmake Mermaid Skin Gel UV](https://lovi.care/skincare/p/canmake/mermaid-skin-gel-uv/for/mature-skin) — Superior fit — [$14.51 at Amazon](https://www.amazon.com/dp/B0CQPR397X?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Hero Cosmetics Force Shield Superlight Sunscreen SPF 30](https://lovi.care/skincare/p/hero-cosmetics/force-shield-superlight-sunscreen-spf-30/for/dry-skin) — Superior fit — [$15.74 at Amazon](https://www.amazon.com/dp/B09R4HGZYW?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [EltaMD UV Daily Broad-Spectrum SPF 40](https://lovi.care/skincare/p/eltamd/uv-daily-broad-spectrum-spf-40/for/dry-skin) — High fit — [$42.00 at Amazon](https://www.amazon.com/dp/B00464EC1E?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use niacinamide and zinc oxide together?

Yes, [niacinamide](https://lovi.care/skincare/ingredients/niacinamide) and [zinc oxide](https://lovi.care/skincare/ingredients/zinc-oxide) work well together to improve acne control and reduce inflammation. You can find both ingredients combined in products like DRMTLGY Broad Spectrum SPF 45 and SKIN1004 Madagascar [Centella](https://lovi.care/skincare/ingredients/centella-asiatica) Air-Fit Suncream Plus.

### Which goes first, niacinamide or zinc oxide?

Niacinamide and zinc oxide work well together and can be combined in light gels or [serums](https://lovi.care/skincare/ingredients/serum) to help improve acne control and inflammation reduction. Products containing both ingredients include DRMTLGY Broad Spectrum SPF 45, Hera Sun Mate Airy Sun Milk, and SKIN1004 Soothing Sun Milk.

### Are niacinamide and zinc oxide good for sensitive skin?

Niacinamide and zinc oxide work well together and help improve acne control and inflammation reduction, making them beneficial for oily and acne-prone skin types.

## Research on niacinamide and zinc oxide

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025

## Other combinations

- Depends on the strength: [Retinol and niacinamide](https://lovi.care/skincare/ingredients/retinol-and-niacinamide)
- Depends on the strength: [AHA blend glycolic and citric acids and niacinamide](https://lovi.care/skincare/ingredients/aha-blend-glycolic-and-citric-acids-and-niacinamide)
- Depends on the strength: [Niacinamide and citric acid](https://lovi.care/skincare/ingredients/niacinamide-and-citric-acid)
- Depends on the strength: [Glycolic acid and niacinamide](https://lovi.care/skincare/ingredients/glycolic-acid-and-niacinamide)
- Depends on the strength: [Niacinamide and lactic acid](https://lovi.care/skincare/ingredients/niacinamide-and-lactic-acid)
- Depends on the strength: [Niacinamide and mandelic acid](https://lovi.care/skincare/ingredients/niacinamide-and-mandelic-acid)
- Depends on the strength: [Niacinamide and salicylic acid](https://lovi.care/skincare/ingredients/niacinamide-and-salicylic-acid)
- Depends on the strength: [Niacinamide and gluconolactone](https://lovi.care/skincare/ingredients/niacinamide-and-gluconolactone)
- Depends on the strength: [Niacinamide and lactobionic acid](https://lovi.care/skincare/ingredients/niacinamide-and-lactobionic-acid)
- Work well together: [Niacinamide and cholesterol](https://lovi.care/skincare/ingredients/niacinamide-and-cholesterol)
- Work well together: [Niacinamide and lauric acid](https://lovi.care/skincare/ingredients/niacinamide-and-lauric-acid)
- Work well together: [Niacinamide and linoleic acid](https://lovi.care/skincare/ingredients/niacinamide-and-linoleic-acid)
- Work well together: [Niacinamide and tri-ceramide complex](https://lovi.care/skincare/ingredients/niacinamide-and-tri-ceramide-complex)
- Depends on the strength: [Adapalene and niacinamide](https://lovi.care/skincare/ingredients/adapalene-and-niacinamide)
- Depends on the strength: [Niacinamide and granactive retinoid](https://lovi.care/skincare/ingredients/niacinamide-and-granactive-retinoid)
- Depends on the strength: [Niacinamide and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/niacinamide-and-hydroxypinacolone-retinoate)
- Depends on the strength: [Niacinamide and pro-retinol](https://lovi.care/skincare/ingredients/niacinamide-and-pro-retinol)
- Depends on the strength: [Niacinamide and retinal](https://lovi.care/skincare/ingredients/niacinamide-and-retinal)
- Depends on the strength: [Niacinamide and retinoid blend](https://lovi.care/skincare/ingredients/niacinamide-and-retinoid-blend)
- Depends on the strength: [Niacinamide and tretinoin](https://lovi.care/skincare/ingredients/niacinamide-and-tretinoin)
- Depends on the strength: [Niacinamide and vitamin A](https://lovi.care/skincare/ingredients/niacinamide-and-vitamin-a)
- Work well together: [Salicylic acid and zinc oxide](https://lovi.care/skincare/ingredients/salicylic-acid-and-zinc-oxide)
- Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/ingredients/niacinamide-and-acetyl-hexapeptide-3)
- Depends on the strength: [Niacinamide and bio-placenta peptides](https://lovi.care/skincare/ingredients/niacinamide-and-bio-placenta-peptides)
- Depends on the strength: [Niacinamide and collagen peptide](https://lovi.care/skincare/ingredients/niacinamide-and-collagen-peptide)
- Depends on the strength: [Niacinamide and copper peptide](https://lovi.care/skincare/ingredients/niacinamide-and-copper-peptide)
- Depends on the strength: [Niacinamide and hexapeptide](https://lovi.care/skincare/ingredients/niacinamide-and-hexapeptide)
- Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/ingredients/niacinamide-and-hexapeptide-9)
- Depends on the strength: [Niacinamide and palmitoyl pentapeptide-4](https://lovi.care/skincare/ingredients/niacinamide-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Niacinamide and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/niacinamide-and-palmitoyl-tripeptide-1)
- Depends on the strength: [Niacinamide and peptide-rich plasma](https://lovi.care/skincare/ingredients/niacinamide-and-peptide-rich-plasma)
- Depends on the strength: [Niacinamide and triple peptide blend](https://lovi.care/skincare/ingredients/niacinamide-and-triple-peptide-blend)
- Work well together: [Niacinamide and hyaluronic acid](https://lovi.care/skincare/ingredients/niacinamide-and-hyaluronic-acid)
- Work well together: [Niacinamide and bakuchiol](https://lovi.care/skincare/ingredients/niacinamide-and-bakuchiol)
- Work well together: [Niacinamide and zinc](https://lovi.care/skincare/ingredients/niacinamide-and-zinc)
- Work well together: [Niacinamide and zinc gluconate](https://lovi.care/skincare/ingredients/niacinamide-and-zinc-gluconate)
- Work well together: [Niacinamide and zinc sulfate](https://lovi.care/skincare/ingredients/niacinamide-and-zinc-sulfate)
- Work well together: [Benzoyl peroxide and niacinamide](https://lovi.care/skincare/ingredients/benzoyl-peroxide-and-niacinamide)
- Keep them apart: [Niacinamide and lipohydroxy acid](https://lovi.care/skincare/ingredients/niacinamide-and-lipohydroxy-acid)
- Work well together: [Ferulic acid and niacinamide](https://lovi.care/skincare/ingredients/ferulic-acid-and-niacinamide)
- Work well together: [Green tea and niacinamide](https://lovi.care/skincare/ingredients/green-tea-and-niacinamide)
- Work well together: [Niacinamide and vitamin E](https://lovi.care/skincare/ingredients/niacinamide-and-vitamin-e)
- Keep them apart: [Niacinamide and isopropyl alcohol](https://lovi.care/skincare/ingredients/niacinamide-and-isopropyl-alcohol)
- Work well together: [Benzoyl peroxide and zinc oxide](https://lovi.care/skincare/ingredients/benzoyl-peroxide-and-zinc-oxide)
- Work well together: [Niacinamide and ascorbyl glucoside](https://lovi.care/skincare/ingredients/niacinamide-and-ascorbyl-glucoside)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/niacinamide-and-zinc-oxide (this page)
- United Kingdom: https://lovi.care/skincare/uk/ingredients/niacinamide-and-zinc-oxide
- Ireland: https://lovi.care/skincare/ie/ingredients/niacinamide-and-zinc-oxide
- Germany: https://lovi.care/skincare/de/ingredients/niacinamide-and-zinc-oxide
- France: https://lovi.care/skincare/fr/ingredients/niacinamide-and-zinc-oxide
- Italy: https://lovi.care/skincare/it/ingredients/niacinamide-and-zinc-oxide
- Netherlands: https://lovi.care/skincare/nl/ingredients/niacinamide-and-zinc-oxide
- Spain: https://lovi.care/skincare/es/ingredients/niacinamide-and-zinc-oxide
- Canada: https://lovi.care/skincare/ca/ingredients/niacinamide-and-zinc-oxide
- Australia: https://lovi.care/skincare/au/ingredients/niacinamide-and-zinc-oxide
- Singapore: https://lovi.care/skincare/sg/ingredients/niacinamide-and-zinc-oxide
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/niacinamide-and-zinc-oxide
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/niacinamide-and-zinc-oxide