# Hydroxypinacolone retinoate

Page: https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Hydroxypinacolone retinoate visibly smooths fine lines, refines skin texture, improves hydration and elasticity, evens out dark spots, and clears acne blemishes. This active ingredient suits dry skin and oily skin best, and it comes in [serums](https://lovi.care/skincare/ingredients/serum). You can easily fit it into a daily routine by keeping it apart from [glycolic acid](https://lovi.care/skincare/ingredients/glycolic-acid), [benzoyl peroxide](https://lovi.care/skincare/ingredients/benzoyl-peroxide), and [vitamin C](https://lovi.care/skincare/ingredients/vitamin-c).

[Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37510902/) [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36762391/)

This page shows hydroxypinacolone retinoate products with a Lovi page. For every product, and a routine built for your skin, use the Lovi app.

### Popular hydroxypinacolone retinoate products

- [The Ordinary Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/p/the-ordinary/granactive-retinoid-2-emulsion/for/oily-skin) — High fit — [$12.10 at Amazon](https://www.amazon.com/dp/B071HHSMTT?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [IOPE Retinol Super Bounce Serum](https://lovi.care/skincare/p/iope/retinol-super-bounce-serum/for/dark-spots) — Average fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0GNTW9PPM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [BYOMA Sensitive Retinol Oil](https://lovi.care/skincare/p/byoma/sensitive-retinol-oil/for/dry-skin) — Average fit — [$17.99 at Amazon](https://www.amazon.com/dp/B0CSDWY381?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube Deep Vita A Retinol Serum](https://lovi.care/skincare/p/medicube/deep-vita-a-retinol-serum/for/acne-prone-skin) — Average fit

### Other hydroxypinacolone retinoate products

- [The Ordinary Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/p/the-ordinary/granactive-retinoid-2-emulsion/for/oily-skin) — High fit — [$12.10 at Amazon](https://www.amazon.com/dp/B071HHSMTT?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [IOPE Retinol Super Bounce Serum](https://lovi.care/skincare/p/iope/retinol-super-bounce-serum/for/dark-spots) — Average fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0GNTW9PPM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube Deep Vita A Retinol Serum](https://lovi.care/skincare/p/medicube/deep-vita-a-retinol-serum/for/acne-prone-skin) — Average fit
- [Sunday Riley A+ High-Dose Retinoid Serum](https://lovi.care/skincare/p/sunday-riley/a-high-dose-retinoid-serum/for/oily-acne-prone-skin) — High fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0B7JT39KP?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [BYOMA Sensitive Retinol Oil](https://lovi.care/skincare/p/byoma/sensitive-retinol-oil/for/dry-skin) — Average fit — [$17.99 at Amazon](https://www.amazon.com/dp/B0CSDWY381?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

## What reviewers say about popular hydroxypinacolone retinoate products

The highlight reviewers mention most for each popular hydroxypinacolone retinoate product on Lovi.

- The Ordinary Granactive Retinoid 2% Emulsion Improves texture ★4.5 · 1.5k+ reviews Lightweight consistency Short shelf life “Felt a change in the texture of my skin from the very first use.” [What people say about Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/p/the-ordinary/granactive-retinoid-2-emulsion/for/oily-skin)
- IOPE Retinol Super Bounce Serum Improves firmness ★4.8 · 200+ reviews Hydrating formula Refines texture “made my face feel so much firmer” [What people say about Retinol Super Bounce Serum](https://lovi.care/skincare/p/iope/retinol-super-bounce-serum/for/dark-spots)
- BYOMA Sensitive Retinol Oil Improves texture ★4.6 · 300+ reviews Lightweight, absorbs fast Hydrating, barrier support “skin was soft the next morning” [What people say about Sensitive Retinol Oil](https://lovi.care/skincare/p/byoma/sensitive-retinol-oil/for/dry-skin)
- Medicube Deep Vita A Retinol Serum Gentle, low irritation ★4.8 · 100+ reviews Improves texture Hydrating, non-drying “only retinol my skin can accept” [What people say about Deep Vita A Retinol Serum](https://lovi.care/skincare/p/medicube/deep-vita-a-retinol-serum/for/acne-prone-skin)

### Hydroxypinacolone retinoate for dry skin

- [The Ordinary Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/p/the-ordinary/granactive-retinoid-2-emulsion/for/dry-skin) — Average fit — [$12.10 at Amazon](https://www.amazon.com/dp/B071HHSMTT?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [BYOMA Sensitive Retinol Oil](https://lovi.care/skincare/p/byoma/sensitive-retinol-oil/for/dry-skin) — Average fit — [$17.99 at Amazon](https://www.amazon.com/dp/B0CSDWY381?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [IOPE Retinol Super Bounce Serum](https://lovi.care/skincare/p/iope/retinol-super-bounce-serum/for/dry-skin) — Average fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0GNTW9PPM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Sunday Riley A+ High-Dose Retinoid Serum](https://lovi.care/skincare/p/sunday-riley/a-high-dose-retinoid-serum/for/dry-skin) — Average fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0B7JT39KP?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube Deep Vita A Retinol Serum](https://lovi.care/skincare/p/medicube/deep-vita-a-retinol-serum/for/dry-skin) — Low fit

### Hydroxypinacolone retinoate for oily skin

- [The Ordinary Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/p/the-ordinary/granactive-retinoid-2-emulsion/for/oily-skin) — High fit — [$12.10 at Amazon](https://www.amazon.com/dp/B071HHSMTT?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Sunday Riley A+ High-Dose Retinoid Serum](https://lovi.care/skincare/p/sunday-riley/a-high-dose-retinoid-serum/for/oily-skin) — Average fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0B7JT39KP?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube Deep Vita A Retinol Serum](https://lovi.care/skincare/p/medicube/deep-vita-a-retinol-serum/for/oily-skin) — Average fit
- [BYOMA Sensitive Retinol Oil](https://lovi.care/skincare/p/byoma/sensitive-retinol-oil/for/oily-skin) — Average fit — [$17.99 at Amazon](https://www.amazon.com/dp/B0CSDWY381?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [IOPE Retinol Super Bounce Serum](https://lovi.care/skincare/p/iope/retinol-super-bounce-serum/for/oily-skin) — Average fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0GNTW9PPM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

### Hydroxypinacolone retinoate for combination skin

- [The Ordinary Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/p/the-ordinary/granactive-retinoid-2-emulsion/for/combination-skin) — High fit — [$12.10 at Amazon](https://www.amazon.com/dp/B071HHSMTT?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Sunday Riley A+ High-Dose Retinoid Serum](https://lovi.care/skincare/p/sunday-riley/a-high-dose-retinoid-serum/for/combination-skin) — Average fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0B7JT39KP?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube Deep Vita A Retinol Serum](https://lovi.care/skincare/p/medicube/deep-vita-a-retinol-serum/for/combination-skin) — Average fit
- [BYOMA Sensitive Retinol Oil](https://lovi.care/skincare/p/byoma/sensitive-retinol-oil/for/combination-skin) — Average fit — [$17.99 at Amazon](https://www.amazon.com/dp/B0CSDWY381?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [IOPE Retinol Super Bounce Serum](https://lovi.care/skincare/p/iope/retinol-super-bounce-serum/for/combination-skin) — Average fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0GNTW9PPM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

### Hydroxypinacolone retinoate for sensitive skin

- [The Ordinary Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/p/the-ordinary/granactive-retinoid-2-emulsion/for/sensitive-skin) — High fit — [$12.10 at Amazon](https://www.amazon.com/dp/B071HHSMTT?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Sunday Riley A+ High-Dose Retinoid Serum](https://lovi.care/skincare/p/sunday-riley/a-high-dose-retinoid-serum/for/sensitive-skin) — Average fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0B7JT39KP?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [IOPE Retinol Super Bounce Serum](https://lovi.care/skincare/p/iope/retinol-super-bounce-serum/for/sensitive-skin) — Average fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0GNTW9PPM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [BYOMA Sensitive Retinol Oil](https://lovi.care/skincare/p/byoma/sensitive-retinol-oil/for/sensitive-skin) — Average fit — [$17.99 at Amazon](https://www.amazon.com/dp/B0CSDWY381?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube Deep Vita A Retinol Serum](https://lovi.care/skincare/p/medicube/deep-vita-a-retinol-serum/for/sensitive-skin) — Average fit

### Hydroxypinacolone retinoate for acne-prone skin

- [The Ordinary Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/p/the-ordinary/granactive-retinoid-2-emulsion/for/acne-prone-skin) — High fit — [$12.10 at Amazon](https://www.amazon.com/dp/B071HHSMTT?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Sunday Riley A+ High-Dose Retinoid Serum](https://lovi.care/skincare/p/sunday-riley/a-high-dose-retinoid-serum/for/acne-prone-skin) — Average fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0B7JT39KP?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube Deep Vita A Retinol Serum](https://lovi.care/skincare/p/medicube/deep-vita-a-retinol-serum/for/acne-prone-skin) — Average fit
- [BYOMA Sensitive Retinol Oil](https://lovi.care/skincare/p/byoma/sensitive-retinol-oil/for/acne-prone-skin) — Average fit — [$17.99 at Amazon](https://www.amazon.com/dp/B0CSDWY381?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [IOPE Retinol Super Bounce Serum](https://lovi.care/skincare/p/iope/retinol-super-bounce-serum/for/acne-prone-skin) — Average fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0GNTW9PPM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)

### Hydroxypinacolone retinoate for mature skin

- [BYOMA Sensitive Retinol Oil](https://lovi.care/skincare/p/byoma/sensitive-retinol-oil/for/mature-skin) — Average fit — [$17.99 at Amazon](https://www.amazon.com/dp/B0CSDWY381?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Sunday Riley A+ High-Dose Retinoid Serum](https://lovi.care/skincare/p/sunday-riley/a-high-dose-retinoid-serum/for/mature-skin) — Average fit — [$50.00 at Amazon](https://www.amazon.com/dp/B0B7JT39KP?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [IOPE Retinol Super Bounce Serum](https://lovi.care/skincare/p/iope/retinol-super-bounce-serum/for/mature-skin) — Average fit — [$49.00 at Amazon](https://www.amazon.com/dp/B0GNTW9PPM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [The Ordinary Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/p/the-ordinary/granactive-retinoid-2-emulsion/for/mature-skin) — Average fit — [$12.10 at Amazon](https://www.amazon.com/dp/B071HHSMTT?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medicube Deep Vita A Retinol Serum](https://lovi.care/skincare/p/medicube/deep-vita-a-retinol-serum/for/mature-skin) — Low fit

## What to combine hydroxypinacolone retinoate with

Ingredient Together How to use them

[Niacinamide](https://lovi.care/skincare/ingredients/niacinamide) Depends Use them at different times of day, applying [niacinamide](https://lovi.care/skincare/ingredients/niacinamide) in the morning and the retinoid at night, because their combined strength can cause irritation. [Hydroxypinacolone retinoate and niacinamide](https://lovi.care/skincare/ingredients/niacinamide-and-hydroxypinacolone-retinoate) [Glycolic acid](https://lovi.care/skincare/ingredients/glycolic-acid) Keep apart Use them on alternate nights because they are too strong to put on your face at the same time. [Hydroxypinacolone retinoate and glycolic acid](https://lovi.care/skincare/ingredients/glycolic-acid-and-hydroxypinacolone-retinoate) [Benzoyl peroxide](https://lovi.care/skincare/ingredients/benzoyl-peroxide) Keep apart Use them at different times of day, applying [benzoyl peroxide](https://lovi.care/skincare/ingredients/benzoyl-peroxide) in the morning and hydroxypinacolone retinoate at night, because they cancel each other out. [Hydroxypinacolone retinoate and benzoyl peroxide](https://lovi.care/skincare/ingredients/benzoyl-peroxide-and-hydroxypinacolone-retinoate) [Vitamin C](https://lovi.care/skincare/ingredients/vitamin-c) Keep apart Use them at different times of day, applying [vitamin C](https://lovi.care/skincare/ingredients/vitamin-c) in the morning and hydroxypinacolone retinoate at night, because combining them causes skin irritation. [Hydroxypinacolone retinoate and vitamin C](https://lovi.care/skincare/ingredients/vitamin-c-and-hydroxypinacolone-retinoate) [AHA blend glycolic and citric acids](https://lovi.care/skincare/ingredients/aha-blend-glycolic-and-citric-acids) Keep apart Use them on alternate nights because combining them can cause severe skin irritation. [Hydroxypinacolone retinoate and aha blend glycolic and citric acids](https://lovi.care/skincare/ingredients/aha-blend-glycolic-and-citric-acids-and-hydroxypinacolone-retinoate) [Salicylic acid](https://lovi.care/skincare/ingredients/salicylic-acid) Keep apart Use them on alternate nights because they can cause too much dryness when layered together. [Hydroxypinacolone retinoate and salicylic acid](https://lovi.care/skincare/ingredients/salicylic-acid-and-hydroxypinacolone-retinoate) [Bio-placenta peptides](https://lovi.care/skincare/ingredients/bio-placenta-peptides) Keep apart Use them at different times of day by applying [bio-placenta peptides](https://lovi.care/skincare/ingredients/bio-placenta-peptides) in the morning and hydroxypinacolone retinoate at night, to avoid extra skin irritation. [Hydroxypinacolone retinoate and bio-placenta peptides](https://lovi.care/skincare/ingredients/bio-placenta-peptides-and-hydroxypinacolone-retinoate) [Hexapeptide](https://lovi.care/skincare/ingredients/hexapeptide) Keep apart Use them at different times of day by applying your peptide product in the morning and your hydroxypinacolone retinoate at night. [Hydroxypinacolone retinoate and hexapeptide](https://lovi.care/skincare/ingredients/hexapeptide-and-hydroxypinacolone-retinoate) [Lactic acid](https://lovi.care/skincare/ingredients/lactic-acid) Keep apart Use them on alternate nights because combining them can cause skin irritation. [Hydroxypinacolone retinoate and lactic acid](https://lovi.care/skincare/ingredients/lactic-acid-and-hydroxypinacolone-retinoate) [Acetyl hexapeptide-3](https://lovi.care/skincare/ingredients/acetyl-hexapeptide-3) Keep apart Use them at different times of day by applying the peptide product in the morning and the retinoid at night to avoid skin irritation. [Hydroxypinacolone retinoate and acetyl hexapeptide-3](https://lovi.care/skincare/ingredients/acetyl-hexapeptide-3-and-hydroxypinacolone-retinoate) [Mandelic acid](https://lovi.care/skincare/ingredients/mandelic-acid) Keep apart Use them on alternate nights, with [mandelic acid](https://lovi.care/skincare/ingredients/mandelic-acid) on one evening and hydroxypinacolone retinoate on the next, because combining them causes irritation. [Hydroxypinacolone retinoate and mandelic acid](https://lovi.care/skincare/ingredients/mandelic-acid-and-hydroxypinacolone-retinoate) [Collagen peptide](https://lovi.care/skincare/ingredients/collagen-peptide) Keep apart Use them at different times of day by applying the peptide product in the morning and the retinoid at night to avoid skin irritation. [Hydroxypinacolone retinoate and collagen peptide](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-collagen-peptide) [Copper peptide](https://lovi.care/skincare/ingredients/copper-peptide) Keep apart Use them at different times of day with [copper peptide](https://lovi.care/skincare/ingredients/copper-peptide) in the morning and hydroxypinacolone retinoate at night, because combining them can cause irritation. [Hydroxypinacolone retinoate and copper peptide](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-copper-peptide) [Citric acid](https://lovi.care/skincare/ingredients/citric-acid) Keep apart Use them on alternate nights because combining them can cause skin irritation. [Hydroxypinacolone retinoate and citric acid](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-citric-acid) [Hexapeptide-9](https://lovi.care/skincare/ingredients/hexapeptide-9) Keep apart Use them at different times of day by applying [hexapeptide-9](https://lovi.care/skincare/ingredients/hexapeptide-9) in the morning and hydroxypinacolone retinoate at night, to avoid extra skin irritation. [Hydroxypinacolone retinoate and hexapeptide-9](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-hexapeptide-9) [Peptide-rich plasma](https://lovi.care/skincare/ingredients/peptide-rich-plasma) Keep apart Use them at different times of day, applying the peptide [serum](https://lovi.care/skincare/ingredients/serum) in the morning and the retinoid at night, to avoid extra skin irritation. [Hydroxypinacolone retinoate and peptide-rich plasma](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-peptide-rich-plasma) [Triple peptide blend](https://lovi.care/skincare/ingredients/triple-peptide-blend) Keep apart Use them at different times of day, applying the peptide blend in the morning and the retinoid at night, to avoid extra skin irritation. [Hydroxypinacolone retinoate and triple peptide blend](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-triple-peptide-blend) [Palmitoyl pentapeptide-4](https://lovi.care/skincare/ingredients/palmitoyl-pentapeptide-4) Keep apart Use them at different times of day by applying the peptide serum in the morning and the retinoid at night to prevent irritation. [Hydroxypinacolone retinoate and palmitoyl pentapeptide-4](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-palmitoyl-pentapeptide-4) [Palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/palmitoyl-tripeptide-1) Keep apart Use them at different times of day by applying the peptide in the morning and the retinoid at night, because combining them can cause irritation. [Hydroxypinacolone retinoate and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-palmitoyl-tripeptide-1)

From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app.

## Questions and answers

### What does hydroxypinacolone retinoate do for the skin?

Hydroxypinacolone retinoate helps improve skin wrinkles, smoothness, elasticity, and hydration while reducing signs of photoaging and blemishes. It may also enhance skin barrier function and reduce microscopic acne features.

[Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37510902/) [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36762391/)

### How do you use hydroxypinacolone retinoate?

You use hydroxypinacolone retinoate at night, and you can pair it with [retinyl propionate](https://lovi.care/skincare/ingredients/vitamin-a) for anti-aging benefits.

[Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36762391/)

### Should you use hydroxypinacolone retinoate in the morning or at night?

You should use hydroxypinacolone retinoate at night. It is typically applied in the evening because certain daytime partner ingredients and sunlight exposure can interact with retinoids.

### Can you use hydroxypinacolone retinoate every day?

Yes, you can use hydroxypinacolone retinoate every day, as studies show it improves skin wrinkles, smoothness, and elasticity over weeks of regular use without causing adverse reactions.

[Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36762391/)

### Does hydroxypinacolone retinoate cause purging or irritation?

Hydroxypinacolone retinoate helps improve skin aging and may cause skin irritation when combined with certain active ingredients. Using it at night while applying incompatible ingredients in the morning helps avoid this issue.

[Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36762391/)

### Which skin types is hydroxypinacolone retinoate best for?

Hydroxypinacolone retinoate is best for oily, combination, sensitive, and acne-prone skin types, with Lovi giving the highest fit rating to The Ordinary [Granactive Retinoid](https://lovi.care/skincare/ingredients/granactive-retinoid) 2% Emulsion for these skin concerns. Sunday Riley A+ High-Dose Retinoid [Serum](https://lovi.care/skincare/ingredients/serum) also achieves a high fit for oily, acne-prone, and dark spot-prone skin.

### Can you use hydroxypinacolone retinoate with glycolic acid?

No, you should keep them apart and use them on alternate nights because they are too strong to put on your face at the same time.

## Research on hydroxypinacolone retinoate

- [Characterization of Acne-Prone Skin with Reflectance Confocal Microscopy and Optical Coherence Tomography and Modifications Induced by Topical Treatment and Probiotic Supplementation](https://pubmed.ncbi.nlm.nih.gov/37510902/) Hydroxypinacolone retinoate · Journal of Clinical Medicine, 2023
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025

## Combining hydroxypinacolone retinoate

- Keep them apart: [Acetyl hexapeptide-3 and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/acetyl-hexapeptide-3-and-hydroxypinacolone-retinoate)
- Keep them apart: [Bio-placenta peptides and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/bio-placenta-peptides-and-hydroxypinacolone-retinoate)
- Keep them apart: [Hydroxypinacolone retinoate and collagen peptide](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-collagen-peptide)
- Keep them apart: [Hydroxypinacolone retinoate and copper peptide](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-copper-peptide)
- Keep them apart: [Hexapeptide and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/hexapeptide-and-hydroxypinacolone-retinoate)
- Keep them apart: [Hydroxypinacolone retinoate and hexapeptide-9](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-hexapeptide-9)
- Keep them apart: [Hydroxypinacolone retinoate and palmitoyl pentapeptide-4](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Hydroxypinacolone retinoate and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-palmitoyl-tripeptide-1)
- Keep them apart: [Hydroxypinacolone retinoate and peptide-rich plasma](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-peptide-rich-plasma)
- Keep them apart: [Hydroxypinacolone retinoate and triple peptide blend](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-triple-peptide-blend)
- Depends on the strength: [Niacinamide and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/niacinamide-and-hydroxypinacolone-retinoate)
- Keep them apart: [AHA blend glycolic and citric acids and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/aha-blend-glycolic-and-citric-acids-and-hydroxypinacolone-retinoate)
- Keep them apart: [Hydroxypinacolone retinoate and citric acid](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-citric-acid)
- Keep them apart: [Glycolic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/glycolic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Lactic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/lactic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Mandelic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/mandelic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Salicylic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/salicylic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Vitamin C and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/vitamin-c-and-hydroxypinacolone-retinoate)
- Keep them apart: [Benzoyl peroxide and hydroxypinacolone retinoate](https://lovi.care/skincare/ingredients/benzoyl-peroxide-and-hydroxypinacolone-retinoate)

## Brands with hydroxypinacolone retinoate

- Canadian skincare: [The Ordinary](https://lovi.care/skincare/brands/the-ordinary)
- Korean skincare: [Medicube](https://lovi.care/skincare/brands/medicube)
- British skincare: [BYOMA](https://lovi.care/skincare/brands/byoma)
- Korean skincare: [IOPE](https://lovi.care/skincare/brands/iope)
- American skincare: [Sunday Riley](https://lovi.care/skincare/brands/sunday-riley)

## Related ingredients

- [Glycolic acid](https://lovi.care/skincare/ingredients/glycolic-acid)
- [Benzoyl peroxide](https://lovi.care/skincare/ingredients/benzoyl-peroxide)
- [Vitamin C](https://lovi.care/skincare/ingredients/vitamin-c)
- [AHA blend glycolic and citric acids](https://lovi.care/skincare/ingredients/aha-blend-glycolic-and-citric-acids)
- [Niacinamide](https://lovi.care/skincare/ingredients/niacinamide)
- [Salicylic acid](https://lovi.care/skincare/ingredients/salicylic-acid)
- [Bio-placenta peptides](https://lovi.care/skincare/ingredients/bio-placenta-peptides)
- [Hexapeptide](https://lovi.care/skincare/ingredients/hexapeptide)
- [Lactic acid](https://lovi.care/skincare/ingredients/lactic-acid)
- [Acetyl hexapeptide-3](https://lovi.care/skincare/ingredients/acetyl-hexapeptide-3)
- [Mandelic acid](https://lovi.care/skincare/ingredients/mandelic-acid)
- [Collagen peptide](https://lovi.care/skincare/ingredients/collagen-peptide)
- [Copper peptide](https://lovi.care/skincare/ingredients/copper-peptide)
- [Citric acid](https://lovi.care/skincare/ingredients/citric-acid)
- [Hexapeptide-9](https://lovi.care/skincare/ingredients/hexapeptide-9)
- [Peptide-rich plasma](https://lovi.care/skincare/ingredients/peptide-rich-plasma)
- [Triple peptide blend](https://lovi.care/skincare/ingredients/triple-peptide-blend)
- [Palmitoyl pentapeptide-4](https://lovi.care/skincare/ingredients/palmitoyl-pentapeptide-4)
- [Palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/palmitoyl-tripeptide-1)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every ingredient with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this ingredient guide: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate (this page)
- United Kingdom: https://lovi.care/skincare/uk/ingredients/hydroxypinacolone-retinoate
- Ireland: https://lovi.care/skincare/ie/ingredients/hydroxypinacolone-retinoate
- Germany: https://lovi.care/skincare/de/ingredients/hydroxypinacolone-retinoate
- France: https://lovi.care/skincare/fr/ingredients/hydroxypinacolone-retinoate
- Italy: https://lovi.care/skincare/it/ingredients/hydroxypinacolone-retinoate
- Netherlands: https://lovi.care/skincare/nl/ingredients/hydroxypinacolone-retinoate
- Spain: https://lovi.care/skincare/es/ingredients/hydroxypinacolone-retinoate
- Canada: https://lovi.care/skincare/ca/ingredients/hydroxypinacolone-retinoate
- Australia: https://lovi.care/skincare/au/ingredients/hydroxypinacolone-retinoate
- Singapore: https://lovi.care/skincare/sg/ingredients/hydroxypinacolone-retinoate
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/hydroxypinacolone-retinoate
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/hydroxypinacolone-retinoate