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Hexapeptide-9 and baking soda

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Hexapeptide-9 and baking soda: keep them apart

Keep them apart

Use them at different times of day, applying the peptide first and the baking soda later, because the baking soda is too harsh for the peptide. Baking soda makes the skin's surface too basic, which stops the peptide from working and can cause irritation or dryness. You can switch to a gentler cleanser or wait longer between using them.

Hexapeptide-9 products

Baking soda products

Questions and answers

Can you use hexapeptide-9 and baking soda together?

No, you should keep hexapeptide-9 and baking soda apart in your routine because peptides lose stability and activity in the highly alkaline environment of baking soda. This high pH causes deamidation and oxidation that can ruin the peptide formula.

Which goes first, hexapeptide-9 or baking soda?

Keep hexapeptide-9 and baking soda apart in your routine because baking soda creates a highly alkaline environment that causes peptides to lose their stability and activity.

Are hexapeptide-9 and baking soda good for sensitive skin?

No, you should keep hexapeptide-9 and baking soda apart in your routine because baking soda creates a highly alkaline environment that causes peptides to lose stability and activity. Lovi rates the compatibility of these two ingredients as low.

Research on hexapeptide-9 and baking soda

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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