# GABA and palmitoyl tripeptide-1

Page: https://lovi.care/skincare/ingredients/gaba-and-palmitoyl-tripeptide-1

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Work well together

Use them together in the same routine, applying [GABA](https://lovi.care/skincare/ingredients/gaba) first and [palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/palmitoyl-tripeptide-1) right after to boost your skin's moisture and firmness. GABA helps plump the skin while the peptide supports firmness, working as a team to make your skin look smoother and healthier. You can keep using them together as long as your skin feels comfortable, but drop down to every other day if you notice any dryness.

- [All about GABA](https://lovi.care/skincare/ingredients/gaba)
- [All about palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/palmitoyl-tripeptide-1)

### [GABA](https://lovi.care/skincare/ingredients/gaba) products

- [Revision Skincare Revox™ Line Relaxer](https://lovi.care/skincare/p/revision-skincare/revoxtm-line-relaxer/for/mature-skin) — High fit

### [Palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/palmitoyl-tripeptide-1) products

- [The Ordinary Multi-Peptide + Copper Peptides 1% Serum](https://lovi.care/skincare/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin) — High fit — [$32.00 at Amazon](https://www.amazon.com/dp/B0C9DXGXZ3?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [The Ordinary Multi-Peptide + HA Serum](https://lovi.care/skincare/p/the-ordinary/multi-peptide-ha-serum/for/dry-skin) — Superior fit — [$19.90 at Amazon](https://www.amazon.com/dp/B0BLHW7JZM?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Medik8 Liquid Peptides](https://lovi.care/skincare/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [$95.00 at Amazon](https://www.amazon.com/dp/B0DT1LYVZ6?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Shiseido Benefiance Wrinkle Smoothing Eye Cream](https://lovi.care/skincare/p/shiseido/benefiance-wrinkle-smoothing-eye-cream/for/mature-skin) — High fit — [$68.00 at Amazon](https://www.amazon.com/dp/B0C9RXV1VY?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Clinique Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [$109.00 at Amazon](https://www.amazon.com/dp/B09FG8TJDD?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Alastin Skincare Regenerating Skin Nectar](https://lovi.care/skincare/p/alastin-skincare/regenerating-skin-nectar/for/mature-skin) — Superior fit
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/p/the-ordinary/matrixyl-10-ha/for/dry-skin) — Superior fit — [$10.90 at Amazon](https://www.amazon.com/dp/B071J1PBQ6?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [ZO Skin Health Daily Power Defense](https://lovi.care/skincare/p/zo-skin-health/daily-power-defense/for/oily-skin) — High fit — [$127.07 at Amazon](https://www.amazon.com/dp/B0GPCPVXB3?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [The INKEY List Collagen Peptide Serum](https://lovi.care/skincare/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin) — High fit
- [Alastin Ultra Nourishing Moisturizer](https://lovi.care/skincare/p/alastin/ultra-nourishing-moisturizer/for/dry-skin) — Superior fit
- [DRMTLGY Needle-less Serum](https://lovi.care/skincare/p/drmtlgy/needle-less-serum/for/dry-skin) — Superior fit — [$69.00 at Amazon](https://www.amazon.com/dp/B0FQKWFFQ6?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Valmont Prime Renewing Pack](https://lovi.care/skincare/p/valmont/prime-renewing-pack/for/mature-skin) — High fit

## Questions and answers

### Can you use GABA and palmitoyl tripeptide-1 together?

[GABA](https://lovi.care/skincare/ingredients/gaba) and [palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/palmitoyl-tripeptide-1) work well together to support structural protein synthesis and moisture balance for all skin types. Lovi rates this combination as Superior.

### Which goes first, GABA or palmitoyl tripeptide-1?

GABA and palmitoyl tripeptide-1 work well together to support structural protein synthesis and moisture balance. Palmitoyl tripeptide-1 may be applied at night for skin benefits.

[Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/)

### Are GABA and palmitoyl tripeptide-1 good for sensitive skin?

GABA and palmitoyl tripeptide-1 work well together by supporting structural protein synthesis and moisture balance for all skin types.

## Research on GABA and palmitoyl tripeptide-1

- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026

## Other combinations

- Keep them apart: [Adapalene and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/adapalene-and-palmitoyl-tripeptide-1)
- Keep them apart: [Granactive retinoid and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/granactive-retinoid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Hydroxypinacolone retinoate and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/hydroxypinacolone-retinoate-and-palmitoyl-tripeptide-1)
- Keep them apart: [Pro-retinol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/pro-retinol-and-palmitoyl-tripeptide-1)
- Keep them apart: [Retinal and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/retinal-and-palmitoyl-tripeptide-1)
- Keep them apart: [Retinoid blend and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/retinoid-blend-and-palmitoyl-tripeptide-1)
- Depends on the strength: [Retinol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/retinol-and-palmitoyl-tripeptide-1)
- Keep them apart: [Tretinoin and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/tretinoin-and-palmitoyl-tripeptide-1)
- Keep them apart: [Vitamin A and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/vitamin-a-and-palmitoyl-tripeptide-1)
- Work well together: [Liposome and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/liposome-and-palmitoyl-tripeptide-1)
- Work well together: [Microcapsule and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/microcapsule-and-palmitoyl-tripeptide-1)
- Depends on the strength: [Vitamin C and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/vitamin-c-and-palmitoyl-tripeptide-1)
- Work well together: [Betaine and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/betaine-and-palmitoyl-tripeptide-1)
- Work well together: [Glycerin and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/glycerin-and-palmitoyl-tripeptide-1)
- Work well together: [Hyaluronic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/hyaluronic-acid-and-palmitoyl-tripeptide-1)
- Depends on the strength: [Niacinamide and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/niacinamide-and-palmitoyl-tripeptide-1)
- Work well together: [Panthenol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/panthenol-and-palmitoyl-tripeptide-1)
- Work well together: [Bakuchiol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/bakuchiol-and-palmitoyl-tripeptide-1)
- Work well together: [Acetyl hexapeptide-3 and GABA](https://lovi.care/skincare/ingredients/acetyl-hexapeptide-3-and-gaba)
- Work well together: [Bio-placenta peptides and GABA](https://lovi.care/skincare/ingredients/bio-placenta-peptides-and-gaba)
- Work well together: [Collagen peptide and GABA](https://lovi.care/skincare/ingredients/collagen-peptide-and-gaba)
- Work well together: [Copper peptide and GABA](https://lovi.care/skincare/ingredients/copper-peptide-and-gaba)
- Work well together: [Hexapeptide and GABA](https://lovi.care/skincare/ingredients/hexapeptide-and-gaba)
- Work well together: [Hexapeptide-9 and GABA](https://lovi.care/skincare/ingredients/hexapeptide-9-and-gaba)
- Work well together: [GABA and palmitoyl pentapeptide-4](https://lovi.care/skincare/ingredients/gaba-and-palmitoyl-pentapeptide-4)
- Work well together: [Arginine and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/arginine-and-palmitoyl-tripeptide-1)
- Work well together: [Silk amino acids and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/silk-amino-acids-and-palmitoyl-tripeptide-1)
- Work well together: [Taurine and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/taurine-and-palmitoyl-tripeptide-1)
- Work well together: [Palmitoyl tripeptide-1 and theanine](https://lovi.care/skincare/ingredients/palmitoyl-tripeptide-1-and-theanine)
- Work well together: [Peptide-rich plasma and GABA](https://lovi.care/skincare/ingredients/peptide-rich-plasma-and-gaba)
- Work well together: [Triple peptide blend and GABA](https://lovi.care/skincare/ingredients/triple-peptide-blend-and-gaba)
- Keep them apart: [AHA blend glycolic and citric acids and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/aha-blend-glycolic-and-citric-acids-and-palmitoyl-tripeptide-1)
- Keep them apart: [Citric acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/citric-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Glycolic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/glycolic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Lactic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/lactic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Mandelic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/mandelic-acid-and-palmitoyl-tripeptide-1)
- Work well together: [Coenzyme Q10 and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/coenzyme-q10-and-palmitoyl-tripeptide-1)
- Work well together: [Green tea and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/green-tea-and-palmitoyl-tripeptide-1)
- Work well together: [Vitamin E and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/vitamin-e-and-palmitoyl-tripeptide-1)
- Work well together: [Beta-sitosterol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/beta-sitosterol-and-palmitoyl-tripeptide-1)
- Work well together: [Ceramide-building complex and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/ceramide-building-complex-and-palmitoyl-tripeptide-1)
- Work well together: [Cholesterol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/cholesterol-and-palmitoyl-tripeptide-1)
- Work well together: [Phytosphingosine and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/phytosphingosine-and-palmitoyl-tripeptide-1)
- Work well together: [Phytosterol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/phytosterol-and-palmitoyl-tripeptide-1)
- Work well together: [Squalene and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/squalene-and-palmitoyl-tripeptide-1)
- Work well together: [Tri-ceramide complex and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/tri-ceramide-complex-and-palmitoyl-tripeptide-1)
- Keep them apart: [Salicylic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/salicylic-acid-and-palmitoyl-tripeptide-1)
- Work well together: [AHA blend glycolic and citric acids and GABA](https://lovi.care/skincare/ingredients/aha-blend-glycolic-and-citric-acids-and-gaba)
- Work well together: [Citric acid and GABA](https://lovi.care/skincare/ingredients/citric-acid-and-gaba)
- Work well together: [Glycolic acid and GABA](https://lovi.care/skincare/ingredients/glycolic-acid-and-gaba)
- Work well together: [Lactic acid and GABA](https://lovi.care/skincare/ingredients/lactic-acid-and-gaba)
- Work well together: [Mandelic acid and GABA](https://lovi.care/skincare/ingredients/mandelic-acid-and-gaba)
- Keep them apart: [Baking soda and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/baking-soda-and-palmitoyl-tripeptide-1)
- Keep them apart: [Bleach and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/bleach-and-palmitoyl-tripeptide-1)
- Keep them apart: [Potassium hydroxide and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/potassium-hydroxide-and-palmitoyl-tripeptide-1)
- Keep them apart: [Behenyl alcohol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/behenyl-alcohol-and-palmitoyl-tripeptide-1)
- Keep them apart: [Isopropyl alcohol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/isopropyl-alcohol-and-palmitoyl-tripeptide-1)
- Keep them apart: [Polyvinyl alcohol and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/polyvinyl-alcohol-and-palmitoyl-tripeptide-1)
- Keep them apart: [Copper and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/copper-and-palmitoyl-tripeptide-1)
- Work well together: [Hyaluronic acid and GABA](https://lovi.care/skincare/ingredients/hyaluronic-acid-and-gaba)
- Keep them apart: [Benzoyl peroxide and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/benzoyl-peroxide-and-palmitoyl-tripeptide-1)
- Keep them apart: [Magnesium and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/magnesium-and-palmitoyl-tripeptide-1)
- Keep them apart: [Zinc and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/zinc-and-palmitoyl-tripeptide-1)
- Keep them apart: [Zinc sulfate and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/zinc-sulfate-and-palmitoyl-tripeptide-1)
- Keep them apart: [Azelaic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/azelaic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Protease and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/protease-and-palmitoyl-tripeptide-1)
- Keep them apart: [Superoxide dismutase and palmitoyl tripeptide-1](https://lovi.care/skincare/ingredients/superoxide-dismutase-and-palmitoyl-tripeptide-1)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/gaba-and-palmitoyl-tripeptide-1 (this page)
- United Kingdom: https://lovi.care/skincare/uk/ingredients/gaba-and-palmitoyl-tripeptide-1
- Ireland: https://lovi.care/skincare/ie/ingredients/gaba-and-palmitoyl-tripeptide-1
- Germany: https://lovi.care/skincare/de/ingredients/gaba-and-palmitoyl-tripeptide-1
- France: https://lovi.care/skincare/fr/ingredients/gaba-and-palmitoyl-tripeptide-1
- Italy: https://lovi.care/skincare/it/ingredients/gaba-and-palmitoyl-tripeptide-1
- Netherlands: https://lovi.care/skincare/nl/ingredients/gaba-and-palmitoyl-tripeptide-1
- Spain: https://lovi.care/skincare/es/ingredients/gaba-and-palmitoyl-tripeptide-1
- Canada: https://lovi.care/skincare/ca/ingredients/gaba-and-palmitoyl-tripeptide-1
- Australia: https://lovi.care/skincare/au/ingredients/gaba-and-palmitoyl-tripeptide-1
- Singapore: https://lovi.care/skincare/sg/ingredients/gaba-and-palmitoyl-tripeptide-1
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/gaba-and-palmitoyl-tripeptide-1
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/gaba-and-palmitoyl-tripeptide-1