Sulwhasoo Timetreasure Renovating Eye Cream Ex for mature skin

Questions and answers

What the research says

• Transdermal emulgel preparations containing 5% ascorbic acid and sodium ascorbyl phosphate both effectively reduced wrinkle depth and enhanced skin elasticity in human volunteers with no statistically significant difference between them.

  Journal of Cosmetic Dermatology, 2021

• Panax ginseng root extract induced Type I procollagen synthesis and COL1A2 promoter activity through Smad2 phosphorylation in human dermal fibroblast cells.

  Journal of Ethnopharmacology, 2007

• A mixture of Panax ginseng and Crataegus pinnatifida prevented skin aging by improving procollagen type I expression, diminishing matrix metalloproteinase-1 secretion, reducing skin roughness and photodamage scores, and decreasing loss of skin moisture in human dermal fibroblasts and healthy human skin.

  Journal of Ginseng Research, 2017

• Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects.

  Rejuvenation Research, 2015

• A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects.

  Journal of Ginseng Research, 2022

• A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline.

  Journal of Toxicology and Environmental Health. Part A, 2020

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism.

  Evidence-based Complementary and Alternative Medicine, 2015

• Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo.

  Experimental Dermatology, 2015

• Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide.

  Advanced Science, 2025

• Topical application of CoQ10 improves mitochondrial function in aging skin in vivo, combating cellular signs of aging caused by an age-dependent shift to a functionally anaerobic energy metabolism.

  BioFactors, 2008

• Encapsulating coenzyme Q10 in lipid nanoparticles for topical use improves skin compatibility, protects against degradation, increases skin penetration, and provides controlled release to counteract aging effects.

  Colloids and Surfaces. B, Biointerfaces, 2023

• Review of topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles highlights their improved bioavailability, chemical stability, skin absorption, and photoprotective effects.

  Antioxidants, 2021

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

Ingredients

Glycyrrhiza Glabra Root Extract Licorice Root Extract, Glyceryl Stearate, Glyceryl Caprylate, Honey, Dextrin, Dimethiconol, Disodium Edta, Portulaca Oleracea Extract, Ophiopogon Japonicus Root Extract, Limnanthes Alba Seed Oil, Behenyl Alcohol, Cetearyl Glucoside, Cetearyl Alcohol, Sodium Ascorbyl Phosphate, Tricholoma Matsutake Extract, Butyrospermum Parkii Butter Shea Butter, Silica Silylate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Ammonium Acryloyldimethyltaurate Vp Copolymer, Ethylhexylglycerin, Nelumbo Nucifera Seed Extract, Ubiquinone, Panax Ginseng Root Extract, Water, Rehmannia Glutinosa Root Extract, Theobroma Cacao Extract, Calcium Pantetheine Sulfonate, Butylene Glycol, Pentaerythrityl Tetraethylhexanoate, Potassium Cetyl Phosphate, Polyglyceryl-3 Methylglucose Distearate, Hydroxypropyl Phosphate Starch, Hydrolyzed Rice Protein, Polygonatum Officinale Root Extract Rhizome, Paeonia Albiflora Root Extract, Pinus Sylvestris Bark Extract, Pinus Sylvestris Leaf Extract, Cyclomethicone, Cyclohexasiloxane, Dimethicone, Cyclopentasiloxane, Urea, Tocopheryl Acetate Vitamin E, Potassium Hydroxide, Phenoxyethanol, Methoxy Peg-114 Polyepsilon Caprolactone, Lilium Tigrinum Stem Extract Flower Leaf, Hydrogenated Poly C6-14 Olefin, Hydrolyzed Ginseng Saponins

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.