# REJURAN DUAL EFFECT AMPOULE for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [REJURAN](https://lovi.care/skincare/ie/brands/rejuran)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration and soothing benefits for your normal skin, with hyaluronic acid and niacinamide supporting moisture retention and texture refinement, while aloe and calendula extracts provide general comfort for redness and irritation.
- Squalane and ceramide NP further aid in barrier repair and emollience, contributing to overall skin health.
- The product is safe for your sensitive skin, as it lacks harsh ingredients and includes soothing components like bisabolol and calendula.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Extract Licorice Extract, Calendula Officinalis Flower Extract

## What the research says

- A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin. ([Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- A blackberry and dill extract combination synergistically increased skin elasticity and induced elastogenesis compared to each ingredient alone and placebo. ([International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/32583541/))
- Tropical highland blackberry juice reduced UVB-mediated DNA damage and increased apoptosis in human epidermal keratinocytes and a reconstituted skin equivalent model. ([Photochemistry and Photobiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23711186/))
- Strawberry and blackberry crude extracts, anthocyanin-enriched fractions, and proanthocyanidin-enriched fractions demonstrated anti-inflammatory effects through ROS reduction, gene expression inhibition, and NO suppression, while anthocyanin fractions promoted fibroblast migration in vitro. ([Food Research International, 2019](https://pubmed.ncbi.nlm.nih.gov/31108769/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical application of Calendula officinalis extract cream significantly improved skin hydration and firmness (reflected in significant changes in R0 and R6 parameters) in 21 healthy human volunteers compared to a base cream. ([Acta Poloniae Pharmaceutica, 2011](https://pubmed.ncbi.nlm.nih.gov/21928714/))
- Treatment with standardized extract of Calendula officinalis L. led to a shorter epithelization time and faster healing speed compared to mineral oil in patients with acute skin loss wounds of the hand and fingers healing by secondary intention. ([Tissue Barriers, 2022](https://pubmed.ncbi.nlm.nih.gov/34674610/))
- Topical administration of Calendula provides weak evidence of effectiveness in acute and chronic wounds compared to standard treatments based on a narrative review of available trials. ([Wounds, 2008](https://pubmed.ncbi.nlm.nih.gov/25941793/))

## What reviewers say

This ampoule is widely praised for delivering the "glass skin" look, with users reporting immediate improvements in hydration, radiance, and skin texture. It is particularly favored by those with aging or damaged skin for its ability to smooth fine lines and repair the skin barrier using its signature salmon DNA (PDRN) formula, though its high price point is a common contention.

- Liked: Instant Glow (mostly mentioned)
- Disliked: High price point (mostly mentioned)
- Liked: Deep Hydration (often mentioned)
- Liked: Texture Smoothing (often mentioned)
- Disliked: Packaging issues (often mentioned)
- Liked: Fast Absorption (sometimes noted)
- Liked: Soothing & Repair (sometimes noted)
- Disliked: Breakouts/Irritation (rarely noted)
- Disliked: Heavy/Sticky finish (rarely noted)
- Disliked: Not hydrating enough (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Rejuran Dual Effect Ampoule work for sensitive skin?

REJURAN DUAL EFFECT AMPOULE works okay for sensitive skin, though other products fit it better. To truly thrive, sensitive skin needs a moisturizing treatment with deeply calming extracts and barrier-strengthening ingredients that soothe irritation without causing any adverse reactions.
Sources: [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/), [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Which ingredients make this ampoule a good fit for sensitive skin?

This ampoule fits sensitive skin well because it includes soothing and calming ingredients like bisabolol, calendula, aloe, and licorice extract that help ease redness and irritation. A product of this type needs rich hydrating and barrier-supporting ingredients like ceramides and hyaluronic acid to fully protect and comfort sensitive skin without causing a reaction.
Sources: [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/), [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### What does Blackberry Leaf Extract do for sensitive skin?

Blackberry Leaf Extract helps calm sensitive skin by reducing redness and soothing irritation. Its antioxidant properties help protect delicate skin from everyday stress.

### What does Licorice Extract do for sensitive skin?

Licorice extract helps calm red and irritated skin and may ease itching. It is generally well-tolerated and works well for soothing sensitive skin.
Sources: [The Journal of Dermatological Treatment, 2003](https://pubmed.ncbi.nlm.nih.gov/14522625/), [Journal of the European Academy of Dermatology and Venereology, 2016](https://pubmed.ncbi.nlm.nih.gov/26805417/)

### Where does this ampoule go in a skincare routine for sensitive skin?

This ampoule goes in the evening routine after your soothing toner and before your moisturizer. Putting treatments in the evening keeps things simple and helps avoid extra irritation around sun exposure.

### Can I use this ampoule with retinol, and in what order?

You can use this ampoule with retinol by applying the ampoule before your retinol treatment at night to help keep your skin comfortable and smooth. Using a hydrating moisturizer beforehand is unlikely to reduce your retinol results and may help prevent dryness and redness as your skin adjusts.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this ampoule?

This treatment is used in the evening as part of your routine. Daily application helps keep sensitive skin calm and soft.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this ampoule clog pores, cause breakouts or purging for sensitive skin?

This ampoule is unlikely to cause breakouts or clogged pores for sensitive skin, as reviewer complaints of breakouts and irritation are low. A product of this type for sensitive skin needs calming extracts and barrier-repairing ingredients to keep skin comfortable.

### Can I use this ampoule around the eyes or on my body?

You can use this moisturizing treatment around the eyes, though sensitive skin on the body and thin areas like eyelids benefit most from products with rich hydrators and barrier-repairing ceramides to keep moisture locked in.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### Is this ampoule fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ie/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/sensitive-skin) — High fit — €37.20 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/ie/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/sensitive-skin) — High fit — €35.40 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/ie/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/sensitive-skin) — High fit — €32.09 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ie/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — €56.86 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/ie/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €21.81 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/ie/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €39.35 at Amazon

## Where to buy

- Amazon.ie: €55.36 (https://www.amazon.ie/dp/B09Z5N7KYD?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Extract Licorice Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract, Peg-6, Glycerin, Water, Hyaluronic Acid, Niacinamide, Dipropylene Glycol, Butylene Glycol, 1,2-Hexanediol, Carbomer, Gerotine Hydrolyzed Dna, Hydrolyzed Dna, Xanthan Gum, Polysorbate 20, Adenosine, Tocopheryl Acetate, Bisabolol, Arbutin, Ethylhexylglycerin, Caprylyl Glycol, Hexylene Glycol, Trehalose, Urea, Serine, Pentylene Glycol, Glyceryl Polyacrylate, Algin, Pullulan, Disodium Phosphate, Potassium Phosphate, Squalane, Hydrogenated Lecithin, Ceramide Np, Oleic Acid, Inulin Lauryl Carbamate, Cholesterol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/sensitive-skin (this page)
- Germany: https://lovi.care/skincare/de/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/rejuran/dual-effect-ampoule/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rejuran/dual-effect-ampoule/for/sensitive-skin