# Perricone MD Rejuvenating Moisturizer for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Perricone MD](https://lovi.care/skincare/ie/brands/perricone-md)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your oily skin, as glycerin and dimethicone provide excellent hydration and smoothing without exacerbating oiliness.
- While it addresses general hydration and soothing for your acne concerns with S-Palmitoylglutathione, it lacks specialized ingredients for directly combating blemishes.
- The product is generally safe for your oily skin, though lactic acid and parfum carry a slight risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Acyl-Glutathione, Tetrahexyldecyl Ascorbate, Ribose, Lactic Acid, Macadamia Ternifolia Seed Oil

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin. ([Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15027519/))
- Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties. ([Journal of the American Academy of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1597538/))
- A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33178384/))

## Why other moisturizers fit oily acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

This moisturizer is praised for its rich texture that plumps, firms, and smooths aging or dry skin without greasiness. Many users report reduced fine lines and improved radiance. Some users experienced product pilling or sensitivity to the fragrance.

- Liked: Deeply hydrating (often mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Non-greasy formula (sometimes noted)
- Liked: Reduces lines (sometimes noted)
- Disliked: Product pilling (sometimes noted)
- Disliked: Fragrance sensitivity (rarely noted)
- Disliked: White cast (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Perricone MD Rejuvenating Moisturizer work for oily acne-prone skin?

Perricone MD Rejuvenating Moisturizer works reasonably well for oily acne-prone skin, as glycerin and dimethicone provide good hydration and smoothing without making your skin more oily. While it helps with general hydration and soothing, it lacks specialized ingredients to directly fight breakouts and carries a slight risk of irritation from lactic acid and parfum. To work best for this skin, a moisturizing treatment needs ingredients that clear blemishes and calm redness without clogging pores or adding heavy oils.

### Which ingredients make this cream a good fit for oily acne-prone skin?

Glycerin and dimethicone make this cream a good fit for your oily skin because they provide smooth hydration without making you oily, and S-Palmitoylglutathione helps soothe your acne concerns. To be a better fit for oily acne-prone skin, a moisturizing treatment needs ingredients that actively combat blemishes and avoid heavy oils and irritation risks.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Acyl-Glutathione do for oily acne-prone skin?

Acyl-glutathione helps protect the skin against sun-induced redness and may improve overall tone. This type of product for oily, acne-prone skin needs ingredients that reduce breakouts and soothe irritation while balancing oil.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/), [Giornale Italiano Di Dermatologia E Venereologia, 2019](https://pubmed.ncbi.nlm.nih.gov/28399620/)

### What does Vitamin C do for oily acne-prone skin?

Vitamin C helps calm red and irritated skin and may improve the look of post-acne marks when used as part of your routine. For oily and acne-prone skin, this type of product also needs soothing ingredients and lightweight hydrators that keep pores clear without feeling heavy.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/28385617/), [Archives of Dermatological Research, 2024](https://pubmed.ncbi.nlm.nih.gov/39708096/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This moisturizer goes after your cleanser and hydrating toner in the morning, and after your evening treatment and cleanser at night. Oily acne-prone skin needs a lightweight moisturizer with blemish-clearing ingredients like salicylic acid or niacinamide.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this cream with retinol, and in what order?

You can use this moisturizing treatment with retinol, applying it after your retinol step to help smooth your skin and keep it hydrated without causing extra oiliness. A product of this type for oily acne-prone skin needs specialized blemish-fighting ingredients alongside light hydrators and soothing agents.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

This cream works well for your oily skin when used twice a day, providing smooth hydration without making you greasy. However, because it lacks specialized ingredients for breakouts, oily acne-prone skin needs products that contain targeted blemish-fighting ingredients and oil-controlling elements to stay clear.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can it clog pores, cause breakouts or purging for oily acne-prone skin?

This moisturizer is unlikely to clog pores or cause breakouts on oily skin, as glycerin and dimethicone provide hydration and smoothing without making skin more oily. However, it lacks specialized ingredients for actively fighting blemishes, and an oily acne-prone skin type needs targeted blemish-fighting ingredients and oil-balancing agents to stay clear.

### Can I use this cream around the eyes or on my body?

You can use this cream on the body, but it is not specifically designed for the very thin skin around the eyes where the eyelid is thinnest. While glycerin and dimethicone provide hydration, this type of product needs specialized targeted ingredients for delicate areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, limonene, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ie/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — €14.07 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ie/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — €18.99 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/ie/p/belif/the-true-cream-aqua-bomb/for/oily-acne-prone-skin) — High fit — €35.01 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — €95.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ie/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ie/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-acne-prone-skin) — Superior fit — €15.64 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, Peg-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum Seed Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin (this page)
- Germany: https://lovi.care/skincare/de/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin
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- Netherlands: https://lovi.care/skincare/nl/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin