# Perricone MD High Potency Retinol Recovery Overnight Moisturizer for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [Perricone MD](https://lovi.care/skincare/ie/brands/perricone-md)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing and treatment for your combination skin due to retinol and sodium hyaluronate, which help smooth texture and hydrate, though they may not fully address oiliness in certain areas.
- Ingredients like squalane and glycerin provide general skincare benefits such as hydration, supporting your skin's overall condition.
- The product is safe for your combination skin with no risks of irritation, as it lacks prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Dmae, Sodium Hyaluronate, Squalane, Ceramide Np

## What the research says

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Daily application of 3% DMAE facial gel for 16 weeks safely and efficaciously mitigates forehead lines and periorbital fine wrinkles, improves lip shape and fullness and overall aging skin appearance, and increases skin firmness compared to placebo. ([American Journal of Clinical Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/15675889/))
- A gel containing 3% 2-dimethylaminoethanol (DMAE) increased skin firmness, demonstrated by increased shear wave velocity in 30 volunteers compared to a formulation without DMAE. ([Skin Research and Technology, 2002](https://pubmed.ncbi.nlm.nih.gov/12236885/))
- A DMAE-based formulation increased dermal and collagen fiber thickness in hairless mice and enhanced stratum corneum water content in human forearm skin compared to control formulations, without significantly modifying mechanical properties. ([Die Pharmazie, 2009](https://pubmed.ncbi.nlm.nih.gov/20095140/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Perricone MD Retinol Recovery Overnight Moisturizer work for combination skin?

This moisturizer works moderately well for combination skin by smoothing texture and hydrating, though it may not fully control oily areas. A product of this type needs brightening and moisturizing ingredients that reduce oily shine without causing irritation, along with soothing agents and antioxidants for well-rounded care.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Which ingredients make this cream a good fit for combination skin?

Retinol and sodium hyaluronate make this cream a good fit by helping smooth texture and hydrate your skin. To work best for combination skin, this type of product also needs brightening ingredients and soothing agents to reduce oily shine and address multiple concerns without causing irritation.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Retinol do for combination skin?

Retinol helps smooth fine lines, even out skin tone, and improve firmness in combination skin. It works by encouraging faster skin renewal and boosting collagen, though it may occasionally cause mild dryness or scaling while your skin adjusts.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does DMAE do for combination skin?

DMAE helps firm combination skin and smooth out fine lines when used daily, though a product of this type needs added hydrating ingredients to keep dry areas soft while balancing oilier zones.
Sources: [American Journal of Clinical Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/15675889/), [Skin Research and Technology, 2002](https://pubmed.ncbi.nlm.nih.gov/12236885/)

### Where does this cream go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and toning, followed by a moisturizer. A product for combination skin needs balancing ingredients that hydrate dry areas while helping control oil and shine.

### Can I use this cream with vitamin C, and in what order?

You can use this cream with vitamin C by applying your vitamin C serum in the morning and saving this retinol treatment for your evening routine. Using them at different times of day helps prevent stinging and irritation while keeping your skin calm and smooth.

### How often should I use this cream?

Use this cream as an evening treatment in your nighttime routine. For combination skin, a product of this type needs lightweight hydrators and oil-balancing ingredients that hydrate dry areas without making oily zones greasy.

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to cause irritation or breakouts on combination skin, as it lacks harsh ingredients, though it may not fully control oiliness in oily areas. Combination skin of this type needs lightweight hydrators and balancing ingredients that smooth texture without feeling heavy.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Can I use this cream around the eyes or on my body?

This cream is safe to use around the eyes or on the body, as it is unlikely to cause irritation on these areas. However, because combination skin needs a balanced formula that hydrates dry spots without making oily zones greasy, a product of this type needs lightweight hydrators and oil-balancing ingredients for the best fit.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, geraniol, and eugenol). Cetearyl alcohol and behenyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for combination skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/ie/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — €18.99 at Amazon
- [Anua Heartleaf 78% Soothing Cream](https://lovi.care/skincare/ie/p/anua/heartleaf-78-soothing-cream/for/combination-skin) — High fit — €35.21 at Amazon
- [Allies of Skin Peptides & Antioxidants Firming Daily Treatment](https://lovi.care/skincare/ie/p/allies-of-skin/peptides-and-antioxidants-firming-daily-treatment/for/combination-skin) — High fit — €136.85 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/ie/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €56.86 at Amazon
- Hydrating Toner: [La Mer The Tonic](https://lovi.care/skincare/ie/p/la-mer/the-tonic/for/combination-skin) — Superior fit — €115.30 at Amazon
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/ie/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — €22.67 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Water, Caprylic Capric Triglyceride, C12-15 Alkyl Benzoate, Propanediol, Shea Ethyl Esters Butter, Dicaprylyl Carbonate, Cetearyl Alcohol, Dimethicone, Squalane, Behenyl Alcohol, Hydrogenated Glycerides, Isoamyl Laurate, Aleurites Moluccana Seed Oil, Glyceryl Stearate, Peg-100 Stearate, Hydrogenated Oil, Hydrogenated Soybean Oil, Ceteareth-20, Glycerin, Phenoxyethanol, Polysilicone-11, Sodium Stearoyl Glutamate, Hydrogenated Olive Oil, Citric Acid, Dimethyl Mea, Petrolatum, Hydrogenated Jojoba Oil, Ethylhexylglycerin, Retinol, Retinyl Linoleate, Xanthan Gum, Polysorbate 20, Parfum, Tetrasodium Glutamate Diacetate, Helianthus Annuus Seed Oil Sunflower Seed Oil, Glycine Soja Soybean Lipids, Maltodextrin, Pentylene Glycol, Cetyl Palmitate, Laureth-23, Disodium Acetyl Glucosamine Phosphate, Sodium Glucuronate, Nephelium Lappaceum Leaf Extract, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Ceramide Np, Sodium Hydroxide, Trideceth-6 Phosphate, Magnesium Aspartate, Zinc Gluconate, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Magnesium Sulfate, Sodium Hyaluronate Crosspolymer, Phytosterols, Tocopherol, Copper Gluconate, Citronellol, Geraniol, Hydroxycitronellal, Eugenol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin (this page)
- Germany: https://lovi.care/skincare/de/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- France: https://lovi.care/skincare/fr/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/perricone-md/high-potency-retinol-recovery-overnight-moisturizer/for/combination-skin