# Osmosis Skincare Renew Level 4 Vitamin A Serum for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: Osmosis Skincare
Category: [Serums and treatments](https://lovi.care/skincare/ie/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily skin; a few serums fit it even better.

## Why this fit

- Excellent suitability for your oily skin is provided by niacinamide and retinal, which work to regulate sebum production and improve skin texture, addressing your oily shine concerns.
- The inclusion of palmitoyl tripeptide-38 and lactic acid further supports skin rejuvenation by promoting cell turnover and collagen synthesis, enhancing overall skin health.
- This formula is safe for your skin, with no reported risks of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-acne-prone-skin): High

## Key ingredients

Vitamin A, Niacinamide, Retinal, Palmitoyl Tripeptide-38, Sodium Hyaluronate

## What the research says

- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on limited data, users find this serum to be a highly effective anti-aging treatment that smooths fine lines and refines skin texture without causing irritation. It is frequently praised for its gentle, hydrating formula and its ability to deliver a noticeable glow. Some users report peeling if the product is overused, and a moderate number find the price point to be high.

- Liked: Gentle & non-irritating (mostly mentioned)
- Liked: Effective anti-aging (often mentioned)
- Liked: Improves texture & tone (often mentioned)
- Liked: Hydrating formula (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Dispenser issues (rarely noted)
- Disliked: Peeling if overused (rarely noted)
- Disliked: Yellow tint (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Osmosis Renew Level 4 a great fit for oily skin?

Osmosis Renew Level 4 is a great fit for oily skin because it contains niacinamide and retinal, which help control excess oil and smooth out skin texture. Lactic acid and peptides also support skin renewal by encouraging fresh cell turnover, keeping your skin healthy and balanced without harsh irritation.
Sources: [International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39102921/), [Aesthetic Surgery Journal, 2025](https://pubmed.ncbi.nlm.nih.gov/40580932/)

### Which ingredients make this serum a good fit for oily skin?

Niacinamide and retinal make this serum a great fit by helping to regulate oil production and improve skin texture to reduce oily shine. Lactic acid and palmitoyl tripeptide-38 further support your skin by promoting cell turnover and collagen synthesis.
Sources: [International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39102921/), [Aesthetic Surgery Journal, 2025](https://pubmed.ncbi.nlm.nih.gov/40580932/)

### What does Vitamin A do for oily skin?

Vitamin A helps manage oily skin by regulating sebum production and preventing clogged pores. It is unlikely to cause excessive dryness when used correctly, and it helps keep skin smooth and clear.
Sources: [Journal of Dermatological Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23473858/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for oily skin?

This serum goes in the evening routine after cleansing and before moisturizing, which keeps things simple and lowers sun sensitivity risks. It helps manage oily shine and smooths texture through ingredients like niacinamide and retinal, with a safe profile that is unlikely to cause irritation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38406974/)

### Can I use this serum with vitamin C, and in what order?

You can use this serum with vitamin C, but it is best to apply vitamin C in the morning and save this treatment for your evening routine to help prevent any potential irritation. Using them at separate times of day allows each active ingredient to work effectively without overloading your skin.

### How often should I use this serum?

This treatment serum works best in your evening routine, starting just once a week so your oily skin can adjust safely. You may gradually use it more often if your skin tolerates it well and shows good results.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38406974/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to clog pores or cause breakouts on oily skin, as its ingredients help control excess oil and smooth texture safely. It may cause mild peeling if you overuse it, but it generally supports clear, healthy skin without harsh reactions.

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (benzyl alcohol) and drying alcohol (alcohol denat).

## Alternatives for oily skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/ie/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — €14.94 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/ie/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — €52.57 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/ie/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — €185.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ie/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €21.45 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/ie/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — €19.99 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ie/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — €16.50 at Amazon

## Where to buy

No store in Ireland has a checked price for this product, so the page shows none.

## Ingredients

Water, Pentylene Glycol, Niacinamide, Phosphatidylcholine, Glycerin, Asiaticoside, Cyclodextrin, Caprooyl Tetrapeptide-3, Chlorella Vulgaris Extract, Epilobium Angustifolium Stem Extract Flower Leaf, Palmitoyl Tripeptide-38, Sodium Hyaluronate, Lactic Acid, Thioctic Acid, Fulvic Acid, Dimethyl Sulfone, Retinal, Beta-Glucan, Hydroxyproline, Grapefruit Peel Oil, Santalum Austrocaledonicum Oil Wood Sandalwood Oil Wood, Rubus Chamaemorus Berry Seed Oil Cloud Berry Seed Oil, Lonicera Caprifolium Flower Extract Honeysuckle Flower Extract, Lonicera Japonica Flower Extract Honeysuckle Flower Extract, Dextran, Hydroxypropyl Cyclodextrin, Xanthan Gum, Alcohol Denat, Potassium Sorbate, Sodium Hydroxide, Benzyl Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin (this page)
- Germany: https://lovi.care/skincare/de/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/osmosis-skincare/renew-level-4-vitamin-a-serum/for/oily-skin