# numbuz:n Pantothenic B5 Active Soothing Serum for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [numbuz:n](https://lovi.care/skincare/ie/brands/numbuz-n)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your dry skin as Panthenol Vitamin B5 and Glycerin provide excellent humectant action, while Hyaluronic Acid enhances barrier resilience and hydration to address dryness and flakiness.
- The inclusion of Centella Asiatica Extract and its derivatives further soothes and calms the skin, complementing the moisturizing benefits for overall skin comfort.
- The product is safe for your dry skin, containing no harsh ingredients and featuring soothing components like Panthenol Vitamin B5 and Centella Asiatica Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-acne-prone-skin): Superior

## Key ingredients

Pantothenic Acid Vitamin B5, Hyaluronic Acid, Centella Asiatica Extract, Allantoin, Niacinamide

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## What reviewers say

This serum is widely praised by users with oily, acne-prone, and dehydrated skin for its ability to deeply hydrate without clogging pores or leaving a greasy residue. While many report significant improvements in redness and oil control, results vary for those with dry skin or specific sensitivities, with some users finding it insufficiently moisturizing on its own.

- Liked: Lightweight & fast (mostly mentioned)
- Liked: Hydrating for oily (often mentioned)
- Liked: Soothing redness (often mentioned)
- Liked: Oil control (sometimes noted)
- Disliked: Not enough moisture (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Price per volume (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes numbuz:n Pantothenic B5 Active Soothing Serum a great fit for dry skin?

This serum is a great fit because panthenol vitamin b5 and glycerin draw moisture into dry skin, while hyaluronic acid helps keep the skin barrier strong and smooth. Centella asiatica extract and allantoin further soothe and calm irritation, making it very comfortable for dry skin types.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this serum a good fit for dry skin?

This serum is a great fit for dry skin because panthenol vitamin b5 and glycerin draw in moisture, while hyaluronic acid helps keep the skin barrier strong and comfortable. Centella asiatica extract also helps soothe and calm the skin to keep dry, flaky areas feeling soft and smooth.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Pantothenic Acid do for dry skin?

Pantothenic Acid helps keep dry skin soft by holding in moisture and calming irritation. It improves how well the skin barrier holds water and makes rough skin feel smooth.
Sources: [Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29577586/)

### What does Hyaluronic Acid do for dry skin?

Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### Where does this serum go in a skincare routine for dry skin?

This serum goes in your evening routine as a treatment step after cleansing and before moisturizing. Putting it in the evening keeps things simple and avoids extra safety concerns around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate your skin and then following with your retinol treatment. This layering helps reduce irritation and keeps your skin feeling soft and comfortable.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

This serum is a great fit for your dry skin and is applied in the evening as part of your routine. Daily application helps boost moisture, soothe dryness, and improve overall comfort.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to cause breakouts on dry skin because it features soothing components like Panthenol Vitamin B5 and Centella Asiatica Extract with no harsh ingredients. Reviewers occasionally report breakouts, but such reactions are low.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this serum around the eyes or on my body?

Yes, you can safely use this serum around the eyes and on the body because it features gentle soothing components like Panthenol Vitamin B5 and Centella Asiatica Extract with no harsh ingredients. The delicate skin around the eyes and various body areas may benefit from the rich moisturizing action of glycerin and hyaluronic acid to help keep skin smooth and comfortable.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/ie/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-skin) — High fit — €35.40 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ie/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dry-skin) — High fit — €37.20 at Amazon
- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/ie/p/kiehl-s/midnight-recovery-concentrate/for/dry-skin) — Average fit — €77.90 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ie/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €14.68 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/ie/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — €14.28 at Amazon
- SPF: [Thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/ie/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — €32.81 at Amazon

## Where to buy

- Amazon.ie: €17.00 (https://www.amazon.ie/dp/B0D176VZP2?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- Notino: €24.50 (https://www.notino.ie/numbuzin/no-1-pantothenic-b5-active-soothing-serum-intensely-hydrating-serum-with-gel-consistency/p-16311692/)
Prices checked 18 Oct – 1 Nov 2026.

## Ingredients

Water, Panthenol Vitamin B5, Glycerin, Butylene Glycol, Hyaluronic Acid, Allantoin, Centella Asiatica Extract, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Beta-Glucan, Sodium Pca, Tocopherol Vitamin E, Caprylyl Glycol, Ethylhexylglycerin, 1,2-Hexanediol, Carbomer, Arginine, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin (this page)
- Germany: https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin