# numbuz:n No.3 Skin Softening Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Ireland.

Brand: [numbuz:n](https://lovi.care/skincare/ie/brands/numbuz-n)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ie/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- This serum is highly suitable for your oily skin, as Bifida Lysate Ferment and Galactomyces Ferment Filtrate work to moisturize and smooth your skin while niacinamide helps regulate sebum production and repair your skin barrier.
- The inclusion of Alteromonas Extract Ferment and silk extract further supports skin texture and hydration, addressing your concerns with blemishes and breakouts.
- The product has a very safe profile for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Bifida Lysate Ferment, Galactomyces Ferment Filtrate, Niacinamide, Sodium Hyaluronate, Squalane

## What the research says

- Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women. ([Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/))
- Daily application of Galactomyces ferment filtrate-containing skin products for 12 months significantly and cumulatively reversed 11-year facial skin aging parameters of wrinkles, hyperpigmented spots, and roughness, and increased skin hydration in 86 female volunteers. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/36769815/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo. ([Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/))
- Galactomyces ferment filtrate promotes epidermal interconnectivity, barrier development, cell adhesion, keratinocyte differentiation and proliferation, and protects cellular bioenergetics against stress in keratinocytes and ex vivo skin explants compared to untreated controls. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38924095/))
- Galactomyces ferment filtrate activates AHR and NRF2, upregulates filaggrin and terminal differentiation markers, exhibits antioxidative activity, promotes antiinflammatory IL-37, and downregulates CDKN2A, IL-33, CXCL14, and IL6R in epidermal keratinocytes. ([Journal of Clinical Medicine, 2022](https://pubmed.ncbi.nlm.nih.gov/36362566/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Based on a very large amount of data, this serum is highly effective at softening and smoothing skin, providing a radiant glow and deep hydration, with many users achieving a 'glass skin' appearance. However, a moderate number of users report breakouts and fungal acne flare-ups, while a low number experience irritation or find the finish sticky. This summary should be definitely taken into account.

- Liked: Softens skin (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Improves radiance (often mentioned)
- Liked: Elegant texture (sometimes noted)
- Disliked: Causes breakouts (sometimes noted)
- Disliked: Causes irritation (rarely noted)
- Disliked: No results (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes numbuz:n No.3 Skin Softening Serum a great fit for oily acne-prone skin?

This serum is a great fit because Bifida Lysate Ferment and Galactomyces Ferment Filtrate help moisturize and smooth your skin while niacinamide regulates oil and repairs your skin barrier. Alteromonas Extract Ferment and silk extract further support skin texture and hydration to address breakouts, and the formula is very safe with no harsh ingredients.
Sources: [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Bifida Lysate Ferment and Galactomyces Ferment Filtrate make this serum a great fit because they moisturize and smooth your oily skin, while niacinamide helps regulate oil production and repair your skin barrier. Ingredients like Alteromonas Extract Ferment and silk extract further support your skin texture and hydration while addressing breakouts.
Sources: [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### What does Bifida Ferment Lysate do for oily acne-prone skin?

Bifida Ferment Lysate helps calm oily acne-prone skin by strengthening your skin barrier and lowering irritation. It is unlikely to clog pores and may help keep your skin feeling smooth and balanced.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### What does Galactomyces Ferment Filtrate do for oily acne-prone skin?

Galactomyces Ferment Filtrate helps calm redness, smooth rough spots, and balance oily skin while keeping it hydrated. It also helps fade dark spots left behind by acne and supports a clear, even look.
Sources: [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in your evening routine as a treatment step after cleansing and toning, and before moisturizing. Putting it in the evening helps keep your routine simple and adds extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to keep your skin calm and hydrated, followed by your retinol product. This helps reduce potential irritation while supporting your skin barrier during treatment.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this serum?

This serum is a great fit for your oily acne-prone skin, and you can use it in your evening routine for simplicity and safety. Bifida Lysate Ferment and Galactomyces Ferment Filtrate help moisturize and smooth your skin while niacinamide regulates oil and repairs your skin barrier.
Sources: [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is a great fit for your oily acne-prone skin because fermented ingredients and niacinamide help smooth your skin and regulate oil without clogging pores. While some reviewers report breakouts, the formula has a very safe profile with a low risk of irritation and no harsh ingredients.
Sources: [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Can I use this serum around the eyes or on my body?

You can use this serum on your body, but you should use caution around the eyes because the skin there is much thinner than on the body. This moisturizing treatment has a very safe profile with soothing components and no harsh ingredients, making irritation unlikely.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/ie/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — €37.20 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/ie/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-acne-prone-skin) — High fit — €35.40 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/ie/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/oily-acne-prone-skin) — High fit — €32.09 at Amazon

## Pairs well with

- Cleanser: [IS Clinical Cleansing Complex](https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — €95.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ie/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/ie/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-acne-prone-skin) — Superior fit — €15.64 at Amazon

## Where to buy

- Amazon.ie: €22.90 (https://www.amazon.ie/dp/B0915K6WD3?tag=lovi-care-web-product02-21&linkCode=osi&th=1&psc=1)
- Notino: €11.90 (https://www.notino.ie/numbuzin/no-3-skin-softening-serum-smoothing-serum-for-radiance-and-hydration/p-16312710/)
Prices checked 10 Oct – 5 Nov 2026.

## Ingredients

Bifida Lysate Ferment, Galactomyces Ferment Filtrate, Butylene Glycol, Methyl Gluceth-20, Water, Niacinamide, Peg-90, 1,2-Hexanediol, Glycerin, Squalane, Alteromonas Extract Ferment, Silk Extract, Goat Extract Milk, Sodium Hyaluronate, Panthenol, Adenosine, Glycereth-26, Xanthan Gum, Polyglyceryl-3 Distearate, Glyceryl Stearate Se, Glyceryl Stearate Citrate, Polyglyceryl-3 Methylglucose Distearate, Carbomer, Tromethamine, Ethylhexylglycerin, Caprylyl Glycol, Tropolone, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin (this page)
- Germany: https://lovi.care/skincare/de/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin